• Journal of Trauma and Injury
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• 제30권4호
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• pp.158-165
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• 2017

Purpose: The purpose of this study was to evaluate the diagnostic accuracy of X-rays in patients with acute traumatic vertebral fractures visiting the emergency department and to analyze the diagnostic value of X-rays for each spine level. Methods: We retrospectively analyzed basal characteristics by reviewing medical records of 363 patients with adult traumatic vertebral fractures, admitted to the emergency center from March 1, 2014 to February 28, 2017. We analyzed spine X-rays and magnetic resonance imaging (MRI) scans to determine distribution according to the vertebral level, and we evaluated the efficacy of X-rays by comparing discrepancies between X-rays and MRI scans. Results: For a total of 363 patients, the mean age was 56.65 (20-93) and 214 (59%) were males. On the basis of X-rays, 67 cases (15.1%) were of the cervical spine, 133 cases (30.0%) were of the thoracic spine, and 243 cases (54.9%) were of the lumbar spine. In particular, the thoracolumbar region (T11-L2) was the most common, with 260 cases (58.7%). In X-rays, fractures were the least in the upper thoracic region (T1-T3), whereas MRI scans revealed fairly uniform distribution across the thoracic spine. Sensitivity of X-rays was lowest in the upper thoracic spine and specificity was almost always greater than 98%, except for 94.7% in L1. Positive predictive value was lower in the mid-thoracic region (T4-T9) and negative predictive value was slightly lower in C6, T2, and T3 than at other sites. Diagnostic accuracy of X-rays by vertebral body, transverse process, and spinous process according to fractured vertebral structures was significantly different according to vertebral level. Conclusions: Diagnostic accuracy of X-rays was lower in the upper thoracic region than in other parts. Further studies are needed to identify better methods for diagnosis considering cost and neurological prognosis.

• Journal of Chest Surgery
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• 제49권4호
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• pp.273-279
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• 2016

Background: The use of extracorporeal life support (ECLS) in the setting of cardiopulmonary resuscitation (CPR) has shown improved outcomes compared with conventional CPR. The aim of this study was to determine factors predictive of survival in extracorporeal CPR (E-CPR). Methods: Consecutive 85 adult patients (median age, 59 years; range, 18 to 85 years; 56 males) who underwent E-CPR from May 2005 to December 2012 were evaluated. Results: Causes of arrest were cardiogenic in 62 patients (72.9%), septic in 18 patients (21.2%), and hypovolemic in 3 patients (3.5%), while the etiology was not specified in 2 patients (2.4%). The survival rate in patients with septic etiology was significantly poorer compared with those with another etiology (0% vs. 24.6%, p=0.008). Septic etiology (hazard ratio [HR], 2.84; 95% confidence interval [CI], 1.49 to 5.44; p=0.002) and the interval between arrest and ECLS initiation (HR, 1.05 by 10 minutes increment; 95% CI, 1.02 to 1.09; p=0.005) were independent risk factors for mortality. When the predictive value of the E-CPR timing for in-hospital mortality was assessed using the receiver operating characteristic curve method, the greatest accuracy was obtained at a cutoff of 60.5 minutes (area under the curve, 0.67; 95% CI, 0.54 to 0.80; p=0.032) with 47.8% sensitivity and 88.9% specificity. The survival rate was significantly different according to the cutoff of 60.5 minutes (p=0.001). Conclusion: These results indicate that efforts should be made to minimize the time between arrest and ECLS application, optimally within 60 minutes. In addition, E-CPR in patients with septic etiology showed grave outcomes, suggesting it to be of questionable benefit in these patients.

• 말소리와 음성과학
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• 제11권4호
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• pp.97-108
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• 2019

한국인 성인을 대상으로 최적의 포먼트 분석이 가능하도록 자동화된 프랏 스크립트를 구현하였다. 최적의 포먼트 분석이란 프랏에서 포먼트 분석 시 설정하는 2가지 세팅 파라미터(최대 포먼트, 포먼트 개수)를 조합하여 측정된 제1, 제2 포먼트의 편차합이 최소일 때를 가리킨다. 포먼트 분석의 신뢰성을 높이기 위해서는 성별이나 모음의 종류에 따라 LPC 차수를 다르게 설정해야 하는데 프랏 매뉴얼에서는 최대 포먼트 설정 값으로 남성 5,000 Hz, 여성 5,500 Hz, 측정개수는 5개를 권고한다. 그러나 이렇게 권고된 포먼트 세팅 설정이 한국어 모음에 대해서도 타당한지 검증이 필요하다. 본 연구에서 구현한 4가지 스크립트를 적용한 결과, 각 모음별 포먼트 산점도로 확인하였을 때 특히 여성의 경우 스크립트에 따라 측정된 포먼트 변이의 폭이 두드러지는 차이를 보였다. 포먼트 산점도와 통계 결과를 통해 linear_script와 qtone_script가 포먼트 측정에서 더 신뢰성이 높은 것을 알 수 있었다. Linear_script, qtone_script에서 최적의 세팅으로 설정된 최대 포먼트와 포먼트 개수의 데이터 경향성을 살펴보면, 전설 모음 [이, 에]의 경우 권고 설정보다 최대 포먼트 값은 높게, 포먼트 개수의 값은 적게 설정되었다. 반면 후설모음 [오, 우]의 경우, 권고 설정보다 최대 포먼트 값은 낮게, 포먼트 개수의 값은 많게 설정되는 것을 확인할 수 있었다.

• 대한골관절종양학회지
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• 제3권1호
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• pp.18-25
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• 1997

Prosthetic replacement is one of the most common methods of reconstruction after resection of malignant tumor around the knee. Gait analysis provides a relative objective data about the gait function of patients with prosthesis. The purpose of this study was to compare the gait pattern of the patients who underwent limb salvage surgery with prosthesis for distal femur and that of patients with prosthesis for proximal tibia. This study included ten patients (4 males, 6 females, mean age 22.7 years, range 14-36) who underwent a wide resection and Kotz hinged modular reconstruction prosthesis replacement and six normal adult(Control). The site of bone tumor was the distal femur (Group 1) in six patients and proximal tibia (Group 2) in 4 patients. The follow-up period ranged from 15 to 82 months (mean : 33 months). The evaluation consisted of clinical assessment, radiographic assessment, gait analysis using VICON 370 Motion Analysis System. The gait analysis included the linear parameters such as, walking velocity, cadence, step length, stride length, stance time, swing time, single support and double support time and the three-dimensional kinematics (joint rotation angle, velocity of joint rotation) of ankle, knee, hip and pelvis in sagittal, coronal and transverse plane. For the kinetic evaluation, the moment of force (unit: Nm/kg) and power (unit: Watt/kg) of ankle, knee and hip joint in sagittal, coronal and transverse plane. In the linear parameters, cadence, velocity, step time and single support were decreased in both group 1 and group 2 compared with control. Double support decreased in group 2 compared with control significantly(p<.05). In contrast to our hypothesis, there was no significant difference between group 1 and group 2. In Kinematics, we observed significant difference (p<.05) of decreased knee flexion in loading response (G2

• Asian Pacific Journal of Cancer Prevention
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• 제13권3호
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• pp.827-831
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• 2012

To determine the relationship between comorbidity and outcome after radical cystectomy in Chinese patients by using the Adult Comorbidity Evaluation (ACE)-27 index. Two-hundred-and-forty-six patients treated with radical cystectomy at the Second Xiangya Hospital of Central South University, Hunan Province, China between 2000 and 2010 were retrospectively analyzed. Medical records were reviewed for age, gender, delayed time of radical cystectomy, urinary diversion type, pelvic lymphadenectomy status, TNM stage, and pathological grade. Comorbidity information was assessed by the ACE-27 index. The outcome measurement was overall survival. Univariate and multivariate Cox proportional hazards regression analyses were used to determine the association between comorbidity and outcome. The study population consisted of 215 (87.40%) males and 31 (12.60%) females with a mean age of $62{\pm}11$ years. Median duration of follow-up was $47{\pm}31$ months. A total of 151 (61.38%) patents died during follow-up. Of those, 118 (47.97%) had at least one comorbidity. According to the ACE-27 scores, 128 (52.03%) patients had no comorbidity, 79 (32.11%) had mild, 33 (13.41%) had moderate, and 6 (2.45%) had severe comorbidities. Multivariate analysis indicated that moderate (p=0.002) and severe (p<0.001) comorbidity was significantly associated with decreased overall survival. In addition, age ${\geq}70$ years (p=0.002), delayed time of radical cystectomy >12 weeks (p=0.044), pelvic lymphadenectomy status (p=0.014), and TNM stage >T3 (p<0.001) were determined to be independent risk factors of overall survival. Increasing severity of comorbidity statistically correlated with decreased overall survival after radical cystectomy.

• 대한치과교정학회지
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• 제38권2호
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• pp.83-94
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• 2008

본 연구는 중안면 함몰이 있는 골격성 III급 부정교합자의 중안면의 형태를 정상 표본과 비교하고, 악교정수술에 의하여 연조직이 어떤 변화를 보이는 지를 알아보기 위하여 시행하였다. 골격성 III급 부정교합으로 진단 받고 상악 전진술과 하악 후퇴술을 시행 받은 환자 34명(남자:15명, 여자:19명)을 대상으로 수술 전후 측모 두부방사선 계측사진을 분석하였다. 골격성 III급 부정교합자의 중안면의 경조직 계측치 S'-Or, Or${\bot}$NA, S'Or/SN, ${\angle}$SNOr에서 남녀모두에서 정상 교합자와 큰 차이가 있었다. 상악골이 평균 5.03 mm 전방이동 될 때 연조직 Orbitale는 2.26 mm전방으로 이동하였으며 상관계수는 0.599였다 (p<0.05). 상악 평면각의 변화(시계방향으로 회전)와 상악골의 수직이동은 연조직 Orbitale의 전방이동과 유의성있는 상관관계가 없었다. 상악골 전방이동에 대한 연조직 Orbitale와 Subnasale의 전방이동 비율은 각각 43.57%, 81.54%였다. 이상의 결과에서 중안면 함몰이 있는 환자는 상악골 전방이동시 상순과 비부 외에도 연조직 Orbitale를 포함한 중안면 연조직이 전방으로 이동하지만, 상악골의 회전이동 및 수직이동에 대해서는 연조직의 변화량이 적었다는 것을 알 수 있었다. 이는 상악골의 수술에 따른 중안면 함몰의 해소를 예측하는데 도움이 될 것이다.

• 대한치과교정학회지
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• 제38권2호
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• pp.121-132
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• 2008

양악 수술 시 상악골의 상방이동을 시행하였을 경우에 상기도의 공간적 구조변화를 평가하기 위하여, 술전, 술후, 술후 6개월 후의 간격으로 두부규격방사선사진을 촬영하여 그 변화량을 분석해 보았다. 술전 교정치료를 시행하여 상악은 Le Fort I 골절단술로 상방이동 시행하였고 동시에 하악은 후방이동 시키는 수술을 시행 받은 24명을 대상으로 하였다 (평균 연령22세 1개월, 남자 9명 여자 15명). 상악골 상방이동에 대한 상기도 공간의 변화와 그에 따른 관련성을 조사한 결과, PAS (R)부위는 술후 (T1) 감소하였으나 (p<0.01) 술후 6개월 후(T2)에는 다시 증가하여 술전과 비교 시, 크기 변화를 관찰할 수 없었고, PAS (NL) 부위는 술후(T1)와 술후 6개월 후(T2)에서 유의성 있는 크기 증가를 보였다. PAS (OL)의 경우, 술후 (T1)증가를 보이다가 술후 6개월 이후(T2)에서 감소하였다. 연구개의 두께는 술후 (T1) 증가를 보이다가 6개월 이후 (T2) 처음과 같거나 약간 감소하는 것으로 나타났으며 FH-uvular 각도는 술후 6개월 이후 증가하였다. 또한 상악골 상방이동에 대한 상기도 공간의 변화를 회귀분석 시행한 결과 양악수술 시 평균 $4.40{\pm}1.14mm$의 상악골 상방이동은 양악 수술 후 상기도 공간의 변화에 큰 영향을 미치지 않는 것으로 나타났다.

• Parasites, Hosts and Diseases
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• 제50권3호
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• pp.191-197
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• 2012

Seroepidemiological changes of Toxoplasma gondii infection among the residents of the islands of Gangwha-gun, Incheon for 2 years were surveyed and evaluated by ELISA using a crude extract antigen. In 2010, sera of 919 adult residents in Gyodong-myeon and 313 adults in Samsan-myeon were collected and checked for IgG antibody titers, which showed 14.5% (133 sera) and 19.8% (62 sera) positive rates, respectively. In 2011, sera of 955 adults in Gyodong-myeon and 341 adults in Samsan-myeon were examined, which showed an increase of positive rates to 23.8% (227 sera) and 31.7% (108 sera), respectively. Totally, the seroprevalence of the first year was 15.8% and it increased rapidly to 25.8% in the second year. The positive rates of both sexes increased simultaneously with the significant ratio of males to females by 1.7-2.2 fold (P<0.05). In both myeons, 661 sera were collected every year and showed changes in optical density (OD) in 177 sera; newly found as positives in 73 persons (11.0%), negative conversion in 10 persons (1.5%), and maintained or increased in 94 persons (14.2%). This rapid increase in the prevalence of toxoplasmosis in Gangwha islands may be due to in part peculiar changes in the toxoplasmic environment of the islands and presumably the consumption of the pork bred domestically within the islands or imported from high endemic nations. It is necessary to find out symptomatic toxoplasmic patients and confirm the risk factors for further infection in the islands of Gangwha-gun.

• Parasites, Hosts and Diseases
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• 제53권4호
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• pp.439-445
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• 2015

A survey of intestinal helminths was undertaken in riparian people in Xieng Khouang Province, Lao PDR. Fecal specimens were collected from 643 people (289 males and 354 females) residing in 4 districts (Nonghet, Kham, Phoukout, and Pek) and were examined by the Kato-Katz technique. The overall helminth egg positive rate was 41.2%, and hookworms revealed the highest prevalence (32.7%) followed by Trichuris trichiura (7.3%) and Ascaris lumbricoides (5.6%). The positive rate for small trematode eggs (STE), which may include Opisthorchis viverrini, heterophyids, and lecithodendriids, was 4.4%. For recovery of adult helminths, 12 STE or nematode/cestode egg-positive people were treated with 40 mg/kg praziquantel and 15 mg/kg pyrantel pamoate, and then purged. Mixed infections with 2 Haplorchis species (H. pumilio and H. taichui), Centrocestus formosanus, Opisthorchis viverrini, a species of cestode (Taenia saginata), and several species of nematodes including hookworms and Enterobius vermicularis were detected. The worm load for trematodes was the highest for H. pumilio with an average of 283.5 specimens per infected person followed by C. formosanus, H. taichui, and O. viverrini. The worm load for nematodes was the highest for hookworms (21.5/infected case) followed by E. vermicularis (3.2/infected case). The results revealed that the surveyed areas of Xieng Khouang Province, Lao PDR are endemic areas of various species of intestinal helminths. The STE found in the surveyed population were verified to be those of heterophyids, particularly H. pumilio.

• 대한후두음성언어의학회지
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• 제20권1호
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• pp.57-62
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• 2009

Background and Objectives : There are few studies reported that specifically examine the laryngeal function in patients with profound hearing loss or deafness, This study was designed to examine videostroboscopic findings and phonetic characteristics in adult patients with prelingually deaf. Materials and Method: Sixteen patients (seven males, nine females) diagnosed as prelingually deaf aged from 19 to 54 years, and were compared with a 20 normal control group with no laryngeal pathology and normal hearing group, Videostroboscopic evaluations were rated by experienced judges on various parameters describing the structure and function of the laryngeal mechanism during comfortable pitch and loudness phonations. Acoustic analysis test were done, and a nasalance test performed to measure rabbit, baby, and mother passage. CSL were measured to determine the first and two formant frequencies of vowels /a/, /i/, /u/, Statistical analysis was done using Mann-Whitney U or Wilcoxon signed ranks test. Results: Videostroboscopic findings showed phase symmetry but significantly more occurrences decrement in the amplitude of vibration, mucosal wave, irregularity of the vibration and increased glottal gap size during the closed phase of phonation, In addition, group of prelingually deaf patients were observed to have significantly more occurrences of abnormal supraglottic activities during phonation. The percentage of shimmer in the group of prelingually deaf patients were higher than in the control group. Characteristics of vowels were lower of the second formant of the vowel /i/. Nasalance in prelingually deaf patients showed normal nasality for all passages, Conclusion: Prelingually deaf patients show stroboscopic abnormal findings without any mucosal lesion, suggesting that they have considerable functional voice disorder. We suggest that prelingually deaf adults should perform vocal training for normalized laryngeal function after cochlear implantation.