• Title/Summary/Keyword: administered channels

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Consumer Acceptance of Cosmetics Labels and Satisfaction Levelwith Cosmetics after Purchase:Viewed by the Type of Distribution Channel

  • Jeong, Hyo-Won;Hwang, Choon-Sup
    • Journal of the Korean Society of Clothing and Textiles
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    • v.35 no.12
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    • pp.1486-1496
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    • 2011
  • The present study analyzed the consumer acceptance of labels, satisfaction with cosmetics after purchase, the relationship between consumer acceptance of cosmetics labels and satisfaction with cosmetics as viewed by type of distribution channel. The study was implemented through a descriptive survey method based on a self-administered questionnaire. The sample consisted of 759 women between the ages of 21 and 49, residing in the area of Seoul, Gwangju, and Gyeonggi Province. There were significant differences in the levels of consideration of labels among consumers from each type of distribution channel. Consumers that prefer door-to-door sales consider the information about ingredients more crucial than consumers who prefer other types of distribution channels, department store consumers consider manufacturer information more important, and consumers who prefer specialty stores/chains and discount stores consider the date of manufacture less important than other types of distribution channels. Significant differences were found in consumer satisfaction with cosmetics after purchasing among consumers from each type of distribution channels. A significant relationship was found between the level of considering the product information listed on the labels and the satisfaction with the cosmetics. With respect to most of the factors, a higher level of label consideration was correlated with a higher satisfaction with cosmetics after purchase.

Influence of $1{\alpha}$, 25-dihydroxyvitamin $D_3$ [1, $25(OH)_2D_3$] on the expression of Sox 9 and the transient receptor potential vanilloid 5/6 ion channels in equine articular chondrocytes

  • Hdud, Ismail M.;Loughna, Paul T.
    • Journal of Animal Science and Technology
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    • v.56 no.8
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    • pp.33.1-33.8
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    • 2014
  • Background: Sox 9 is a major marker of chondrocyte differentiation. When chondrocytes are cultured in vitro they progressively de-differentiate and this is associated with a decline in Sox 9 expression. The active form of vitamin D, 1, 25 $(OH)_2D_3$ has been shown to be protective of cartilage in both humans and animals. In this study equine articular chondrocytes were grown in culture and the effects of 1, 25 $(OH)_2D_3$ upon Sox 9 expression examined. The expression of the transient receptor potential vanilloid (TRPV) ion channels 5 and 6 in equine chondrocytes in vitro, we have previously shown, is inversely correlated with de-differentiation. The expression of these channels in response to 1, 25 $(OH)_2D_3$ administration was therefore also examined. Results: The active form of vitamin D (1, 25 $(OH)_2D_3$ when administered to cultured equine chondrocytes at two different concentrations significantly increased the expression of Sox 9 at both. In contrast 1, 25 $(OH)_2D_3$ had no significant effect upon the expression of either TRPV 5 or 6 at either the protein or the mRNA level. Conclusions: The increased expression of Sox 9, in equine articular chondrocytes in vitro, in response to the active form of vitamin D suggests that this compound could be utilized to inhibit the progressive de-differentiation that is normally observed in these cells. It is also supportive of previous studies indicating that $1{\alpha}$, 25-dihydroxyvitamin $D_3$ can have a protective effect upon cartilage in animals in vivo. The previously observed correlation between the degree of differentiation and the expression levels of TRPV 5/6 had suggested that these ion channels may have a direct involvement in, or be modulated by, the differentiation process in vitro. The data in the present study do not support this.

Effect of Hwangryunhaedok-tang on Blood Pressure and Renal Functions in Spontaneously Hypertensive Rats (황연해독탕(黃連解毒湯)이 자발적(自發的) 고혈압(高血壓) 백서(白鼠)의 혈압(血壓) 신장(腎臟) 기능(機能)에 미치는 영향(影響))

  • Kook Yoon-Bum
    • Herbal Formula Science
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    • v.10 no.1
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    • pp.113-129
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    • 2002
  • The present study designed to investigate whether hwangryunhaedok-tang show an anti-hypertensive effect and elucidate its possible mechanism in spontaneously hypertensive rats. The systolic blood pressures (SBP) were significantly decreased as an oral administration of hwangryunhaedok-tang compared with their control group. The urine volume was significantly increased by administration of hwangryunhaedok-tang but urinary sodium (UNaV), potassium (UKV), chloride excretion (UCIV) were not remarkably affected. The urinary creatinine excretion rate (UcrV) was significantly increased in rats administered with hwangryunhaedok-tang in association with increase of creatinine clearance (Ccr). The urine osmolality (Uosmol) was significantly decreased in SHR administered with hwangryunhaedok-tang without being changed in solute-free water reabsorption ( TcH20). The expressions of Aquaporin 2 (AQP-2). 3 and ${\alpha}\;1$, ${\beta}\;1$ subunits of Na.K-ATPase were determined by Western blot analysis to assess the role of these proteins in association with changes of renal functions in SHR administered with hwangryunhaedok-tang. The expression of AQP-2 and 3 protein was significantly down-regulated in the kidney of SHR administered with hwangryunhaedok-tang compared with those in control rats without being altered expression of ${\alpha}\;1$, ${\beta}\;1$ subunits of Na,K-ATPase. In the in vitro assay, Angiotensin converting enzyme (ACE) was inhibited by hwangryunhaedok-tang in a dose-dependent manner. Berberine and/or palmatine, which are well known as a main components of hwangryunhaedok-tang, also have an ACE inhibitory effects in a dose-dependent manner. Taken together, these results suggest that hwangryunhaedok-tang lowered blood pressure through the increase of diuresis caused by down-regulation of water channels and the inhibition of Angiotensin converting enzyme.

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A Study on the Benefits Sought Information Sources Utilized by Consumers Based on the Distribution Channels of Herbal Cosmetics (유통경로에 따른 한방 화장품 추구혜택 및 정보원에 관한 연구)

  • Lee, Seung-Min
    • Journal of the Korean Home Economics Association
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    • v.45 no.10
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    • pp.33-44
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    • 2007
  • The aims of this study were to examine the characteristics of consumer groups by distribution channel and to identify the variables that influence consumers' intentions to purchase herbal cosmetics. Self-administered questionnaires were distributed to 1,000 women between ages of 20 and 50 years who had purchased herbal cosmetics between November 6, 2006 and December 15, 2006 and currently live in Seoul, Kyung-gi, Pusan, Kyung-Nam, Daegu and Kyung-pook province. A total of 900 questionnaires were used in the final analysis. Factor analysis, $x^2$-test, t-test, frequency, one-way ANOVA and stepwise regression analysis were utilized. The results were as follows: 1. There was a correlation between the demographic characteristics of the consumers and the distribution channel they utilized. 2. There was a correlation between the benefits sought by consumers and the distribution channel they utilized. 3. There was a relationship between the sources of the consumer information leading to the purchase and the distribution channel utilized. 4. There was a relationship between the variables influencing consumers' intentions to purchase the products and the distribution channel they utilized.

Systemic Administration of the Potassium Channel Activator in the Polystyrene Latex Bead-Induced Cerebral Vasospasm (Polystyrene Latex Bead에 의한 뇌혈관연축 모델에서 K+ 통로활성제의 전신투여)

  • Jang, Sung Jo;Kang, Sung Don;Yun, Ki Jung
    • Journal of Korean Neurosurgical Society
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    • v.29 no.6
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    • pp.719-724
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    • 2000
  • Objectives : It has been reported that the presence of a pharmacologically inactive foreign substance, polystyrene latex bead, in subarachnoid space activates a non-specific immunological response and elicits arterial narrowing. Recently the activation of potassium($K^+$) channels may be of benefit in relieving cerebral vasospasm. The present study examined the effects of systemic administration of a ATP-sensitive $K^+$ channel activator, cromakalim, on the polystyrene latex bead-induced cerebral vasospasm. Methods : The spasm models similar to that caused by subarachnoid blood injection were created by injection of bead into rabbit cisterna magna. Intravenous injections of cromakalim were administered twice daily(bid) 30 minutes after induction of vasospasm. Animals were killed by perfusion-fixation 2 days after vasospasm. Basilar arteries were removed and sectioned, and the luminal cross-sectional areas were measured. Results : Injection of bead elicited an arterial constriction, reducing arterial diameter to 33.3% of resting tone. Cromakalim inhibited bead-induced constriction at a dose of 0.3mg/kg(Mann-Whitney test, p<0.01). Conclusion : These results support the concept that the cellular events triggered by inactivation of ATP-sensitive $K^+$ channels are responsible for the pathogenesis of vasospasm. The findings also indicate that cromakalim represents a potential therapeutic agents for the treatment of cerebral vasospasm.

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Antecedents of Purchase Decision of Over-The-Counter (OTC) Medicine from Pharmaceutical Distribution Channels in Jordan

  • ALMRAFEE, Mohammad Nabeel Ibrahim
    • Journal of Distribution Science
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    • v.21 no.1
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    • pp.1-12
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    • 2023
  • Purpose: The primary purpose of this research is to understand the potential influence of various factors, namely, pharmacies' recommendations, families' and friend recommendations, price, country of origin, and past experience, on the purchasing decision of nonprescription medicines in the Jordanian context. Research design, data, and methodology: A survey was conducted among 220 Jordanian consumers through a self-administered questionnaire. Further, the authors utilized the mall intercept method as a convenience sampling technique to recruit the respondents who shop at different pharmacies. The data were analyzed using various statistical techniques, such as frequency and percentage for describing the demographics of the sample, Cronbach's alpha for testing the reliability of the data, skewness and kurtosis to check the normality of data, and further, multiple regression using SPSS version 25 was performed for examining the hypotheses. Results: The findings revealed that pharmacists' recommendation, recommendations from friends and family, and price positively influenced consumers' purchase decisions of OTC medicines in Jordan, whereas consumers' past experience and country of origin had no influence on consumers' purchasing decisions of OTC medicines. Conclusions: The paper examines the influence of various factors on customers' purchase decisions of OTC medicines, draws conclusions, and makes recommendations. Also, research limitations are mentioned.

A Study on Characteristics of Fashion Opinion Leaders (패션 의견선도자(意見先導者)의 특성(特性)에 관한 연구(硏究) - 인구통계적(人口統計的).심리적(心理的).패션 커뮤니케이션 경로(經路) 변인(變因)을 중심으로 -)

  • Chung, Hyei-Young
    • Journal of the Korean Society of Costume
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    • v.14
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    • pp.185-198
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    • 1990
  • The purpose of this study is to identify and profile Korean women's fashion opinion leaders on demographic, psychological and communication channels dimensions. The questionnaire was administered to 1204 students from a purposively selected. women's universities in Seoul. The data was analyzed using $X^2$-test, t-test, multiple regression analysis and discriminant analysis, The significance level was set at. 05. The major findings derived from analysis are as follows: 1. Fashion opinion leaders are generally come from families with higher income, more education and higher occupational status than followers. 2. Fashion opinion leaders are more likely to be exhibitionistic, self-confident, individualistic, risk taking and gregarious than followers. 3. Fashion opinion leaders are more exposed to impersonal communication media, especially to fashion magazines than followers. These findings imply an obvious usefulness for both manufacturers in the apparel industry as well as retailers to help them in the identification of their target market for the introduction and acceptance of fashion items.

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A Study on the Recognition about Food Preparation and Cooking Ability of College Students majoring in Food & Nutrition and Others (식품영양학전공 및 비전공대학생들의 식품조리에 관한 의식과 조리능력 수준에 대한 조사)

  • 윤계순
    • Korean journal of food and cookery science
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    • v.17 no.6
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    • pp.639-647
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    • 2001
  • The purpose of this study was to examine the recognition about food preparation and cooking ability of college students majoring in food & nutrition and others. Data were collected from 729 students residing in Chonbuk area by using a self-administered questionnaire. Food and nutrition major students got significantly higher scores than non-major. ones in the recognition of significance and interest in cooking activity. Both food and nutrition major and non-major female students recognized the necessity of cooking ability than non-major male students. Sixty eight percent of the subjects answered that they have aided often his or her family to cook at home. The students majoring in food and nutrition were interested in various fields such as Korean, western style and fusion food. Most of the respondents teamed how to cook from family at home; however major students have learned cooking not only from family but also from various channels such as culinary school, TV and books. The practical use of knowledge about food science was very low in most respondents. The cooking methods used frequently were sauteing, broiling and deep-fat-frying. This study showed that both food and nutrition major and non-major students recognized the necessity of cooking ability and had interests in cooking activity, but cooking ability of non-major ones was significantly lower than that of major students, and the traditional consciousness that women have to take charge of cooking at home tends to be decreasing.

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Predictors of Smoking Cessation Counselling Activities among Community Health Practitioners (보건진료원의 금연지도활동에 영향을 주는 요인 - 광주$\cdot$전남지역을 중심으로 -)

  • 김진선
    • Korean Journal of Health Education and Promotion
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    • v.20 no.3
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    • pp.239-254
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    • 2003
  • Purposes: The purposes of this study were to investigate the smoking cessation counselling activities among community health practitioners(CHP) and to identify the predictors of their smoking cessation counselling activities. Method: A descriptive-correlation study using self-administered questionnaires was conducted. Questionnaires were mailed to all the CHP in a community. A total of 330 CHPs participated in this survey. Results: Of the CHPs surveyed, 245(74.2%) returned completed questionnaires. Most CHPs(90.7%) believed that if a health professional advises their patient to quit, the patient's chances of quitting smoking are increased. While the majority of CHPs “asked, advised, and assessed” their clients, a minority of CHPs “assisted, arranged, and recorded”. In the final stepwise multiple regression model, attitude about smoking cessation policies and counselling activities, self-efficacy of smoking cessation counselling knowledge and skills, and perceived barriers of smoking cessation counselling activities were identified as significant predictors of smoking cessation counselling activities among CHPs. Conclusion: Smoking cessation counselling activities are not a routine part of CHP practice. Efforts should be made to increase the self-efficacy of smoking cessation counselling knowledge and skills among CHPs. Helping CHPs to overcome their barriers to smoking counselling may open up new channels for smoking intervention.

Development of an EEG Based Discriminant-Scale for Scientifically Gifted Students in Elementary School (초등학교 과학 영재아의 뇌파 기반 변별 척도 개발)

  • Kwon, Suk-Won;Kang, Min-Jung;Shin, Dong-Hoon;Kwon, Yong-Ju
    • Journal of Korean Elementary Science Education
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    • v.25 no.spc5
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    • pp.556-566
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    • 2007
  • The purpose of this study was to develop an electroencephalogram (EEG) based differential-scale for scientifically gifted students in elementary school. For this study, signals of EEG with 19 channels were recorded during the generation of our scientific hypothesis using 22 scientifically gifted students, and with 49 average students being used as the control group. IQ, TCT and knowledge generation (KG) as constructs of the scientifically gifted were administered for both the scientifically gifted and the normal, control group elementary students. A 'gifted' value was added to paper test scores of the IQ, TCT, and KG constructs in order to make a personal standardization score for the gifted students. As a dependent variable, the groups were divided by means of the standardization scores thus produced and as an autonomous variable, various EEG parameters were presented through linear analysis, nonlinear analysis, and interdependency measures of the EEG. Multiple linear regression analysis was applied successfully to explain the EEG parameters and to show the characteristics of the scientifically-gifted. The discrimination analysis was administered through the results of multiple linear regression of the EEG parameters thus produced. This study represents the foundation of the development of an EEG based discriminant-scale for scientifically gifted students in elementary school, because it will be able to faithfully discriminate between scientifically-gifted and average students. The results of this study indicates that most of the EEG parameters produced can contribute to predicting the characteristics of the scientifically-gifted in that they express the degree of mutual information and the coherence of mutuality. Accordingly, mutual connectivity which appears to originate in the brain seems to the core of discrimination.

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