• 제목/요약/키워드: acute inflammatory polyneuropathy

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Subacute Inflammatory Demyelinating Polyneuropathy Combined with Optic Neuritis (시신경염이 동반된 아급성염증탈수초다발신경병)

  • Kim, Sieun;Park, Kang Min;Park, Jinse;Ha, Sam Yeol;Kim, Sung Eun;Kim, Jong Kuk;Shin, Kyong Jin
    • Annals of Clinical Neurophysiology
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    • v.15 no.1
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    • pp.13-18
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    • 2013
  • It was sometimes difficult to differentiate between acute-onset chronic inflammatory demyelinating polyneuropathy (A-CIDP) and subacute inflammatory demyelinating polyneuropathy (SIDP). The CNS involvement of these polyneuropathies has rarely reported in the literature. We present the case of a 42-year-old man who developed rapidly developing inflammatory demyelinating polyneuropathy followed by right optic neuritis. This case showed progressive motor weakness and sensory dysfunction with time to nadir at 8 weeks, demyelination in nerve conduction study, no other etiology of neuropathy, no relapse during follow-up of 18 months, good response to steroid and complete recovery which favor SIDP more than A-CIDP. We experienced the case of SIDP associated with optic neuritis.

A Case of IgA λ Monoclonal Gammopathy of Undetermined Significance Mimicking Acute Inflammatory Demyelinating Polyradiculoneuropathy (급성 염증성 탈수초성 다발성 신경병의 임상 양상을 보인 IgA λ형 Monoclonal Gammopathy of Undetermined Significance 1례)

  • Lee, Yeong-Bae;Jeon, Seong-Ho;Han, Dong-Chul;Shin, Dong-Jin
    • Annals of Clinical Neurophysiology
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    • v.7 no.1
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    • pp.17-19
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    • 2005
  • Polyneuropathy that is associated with monoclonal gammopathy of undetermined significance (MGUS) similar to chronic inflammatory demyelinating polyneuropathy (CIDP) has been reported before, whereas a connection to acute inflammatory demyelinating polyneuropathy (AIDP) has not been. A 52 year-old man was presented with ascending paralysis beginning 1 day ago. Neurological examinations showed facial diplegia and decreased motor power and deep tendon reflexes in all extremities. On electrophysiologic study, sensorimotor polyneuropathy was observed. Protein-and immunoelectrophoresis revealed IgA $\lambda$ monoclonal gammopathy. High dose steroid therapy was given and the symptoms improved slightly.

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A Clinical Case Study of Guillain-Barré Syndrome with Chronic Progression (만성적 경과관찰을 보이는 Guillain-Barré Syndrome 환자 1례)

  • Roh, Ji-ae;Jang, Jae-won;Lee, Gi-eon;Hong, Jung-soo;Kim, Dong-jin
    • The Journal of Internal Korean Medicine
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    • v.39 no.1
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    • pp.76-83
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    • 2018
  • Objectives: This case study reports on one patient presenting atypical and chronic disorders after being diagnosed with $Guillain-Barr{\acute{e}}$ Syndrome (GBS). Methods: One patient was treated by Yeongseonjetong-eum-gami, Taklisodok-eum-gami, electroacupuncture, and physical therapy. Any improvement in symptoms was assessed by measuring changes in the motor grade of upper limb weakness, the numerical rating scale (NRS) of lower limb numbness, and GBS scores. Results: After 24 days of treatment, the patient's symptoms of GBS showed little improvement. Conclusions: Traditional Korean medical treatment appeared to be effective in reducing GBS symptoms, but more research is required to confirm these results. When treating GBS patients, the clinician should put effort into distinguishing GBS from other nervous disorders, such as acute onset Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).

Acute-onset chronic inflammatory demyelinating polyneuropathy following hepatitis A virus infection

  • Jung, Eui Sung;Kim, Ye Sel;Min, Ju-Hong;Kang, Kyusik;Lee, Jung Ju;Park, Jong-Moo;Kim, Byung-Kun;Kwon, Ohyun
    • Annals of Clinical Neurophysiology
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    • v.19 no.1
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    • pp.50-53
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    • 2017
  • An infection is less likely to elicit chronic inflammatory demyelinating polyneuropathy (CIDP) than Guillain-$Barr{\acute{e}}$ syndrome. We here report a case of acute-onset CIDP following hepatitis A virus infection and briefly comment on the potential mechanisms regarding the induction and chronicity of autoimmunity after a viral infection.

A Case of Critical Illness Polyneuropathy and Myopathy (중환자 다발신경병증 및 근육병 1예)

  • Moon, So-Young;Lee, Sang-Soo;Lee, Sung-Hyun;Shin, Dong-Ick
    • Annals of Clinical Neurophysiology
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    • v.9 no.1
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    • pp.19-22
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    • 2007
  • Critical illness polyneuropathy (CIP) and critical illness myopathy (CIM) occur commonly in the patients who have been on mechanical ventilation for more than 1 week. Even in some patients diagnosed with CIP, an underlying myopathy may be the primary cause of the muscle weakness. The cormorbid status of CIP and CIM is called as critical illness polyneuropathy and critical illness myopathy (CIPNM). We describe a 56-year-old man with acute quadriparesis and areflexia after systemic inflammatory response syndrome. The diagnosis of CIPNM is important to avoid unnecessary investigations and unreasonably pessimistic prognosis. Electrophysiologic studies are essential for the diagnosis and for planning further clinical management.

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Chronic inflammatory demyelinating polyneuropathy in children: a report of four patients with variable relapsing courses

  • Chang, Soo Jin;Lee, Ji Hyun;Kim, Shin Hye;Lee, Joon Soo;Kim, Heung Dong;Kang, Joon Won;Lee, Young Mock;Kang, Hoon-Chul
    • Clinical and Experimental Pediatrics
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    • v.58 no.5
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    • pp.194-198
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    • 2015
  • Chronic inflammatory demyelinating polyneuropathy (CIDP) is a chronically progressive or relapsing symmetric sensorimotor disorder presumed to occur because of immunologic antibody-mediated reactions. To understand the clinical courses of CIDP, we report variable CIDP courses in children with respect to initial presentation, responsiveness to medical treatment, and recurrence interval. Four patients who were diagnosed with acute-onset and relapsing CIDP courses at Severance Children's Hospital, Seoul, Korea, were enrolled in this retrospective study. We diagnosed each patient on the basis of the CIDP diagnostic criteria developed in 2010 by the European Federation of Neurological Societies/Peripheral Nerve Society Guidelines. We present the cases of four pediatric patients diagnosed with CIDP to understand the variable clinical course of the disease in children. Our four patients were all between 8 and 12 years of age. Patients 1 and 2 were diagnosed with acute cerebellar ataxia or Guillain-$Barr{\acute{e}}$ syndrome as initial symptoms. While patients 1 and 4 were given only intravenous dexamethasone (0.3 mg/kg/day) for 5 days at the first episode, Patients 2 and 3 were given a combination of intravenous immunoglobulin (2 g/kg) and dexamethasone (0.3 mg/kg/day). All patients were maintained with oral prednisolone at 30 mg/day, but their clinical courses were variable in both relapse intervals and severity. We experienced variable clinical courses of CIDP in children with respect to initial presentation, responsiveness to medical treatment, and recurrence interval.

Atypical Guillain-Barr$\acute{e}$ Syndrome Misdiagnosed as Lumbar Spinal Stenosis

  • Jung, Dae Young;Cho, Keun-Tae;Lee, Seung Chul
    • Journal of Korean Neurosurgical Society
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    • v.53 no.4
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    • pp.245-248
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    • 2013
  • Guillain-Barr$\acute{e}$ syndrome (GBS) is an acute inflammatory demyelinating polyneuropathy. In typical cases, the first symptoms of GBS are pain, numbness, paresthesia, weakness in the limbs. Autonomic involvement is common and causes urinary retention and ileus. Much of these symptoms overlap with those of lumbar spinal stenosis. Therefore, correct diagnosis of GBS in a patient with symptomatic lumbar spinal stenosis or in a patient with atypical manifestations of GBS can be difficult, especially early in the course of GBS. Here, we report on a case of atypical GBS in a 74-year-old previously healthy patient with lumbar spinal stenosis and discuss the differential diagnosis of the GBS and lumbar spinal stenosis.

A case report of Guillain-Barre syndrome (Guiillain-Barre 증후군 환자의 치험 1례)

  • Kim, Ki-Hoon;Shin, Dong-Gil;Lee, Jin-Yong;Cho, Baek-Gun
    • The Journal of Pediatrics of Korean Medicine
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    • v.17 no.2
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    • pp.199-211
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    • 2003
  • Objective : This is clinical report about the Wei syndrome(?證)-patient diagnosed as Guillian-Barre syndrome. Guillain-Barre syndrome(GBS), what is called acute inflammatory polyneuritis, is a disorder in which the body's immune system attacks parts of peripheral nervous system. GBS is subclassified into acute inflammatory demyelinating polyneuropathy(AIDP), acute motor or motor-sensory axonal neuropathy(AMAN, AMSAN), and the other variants. The cause and mechanism of this syndrome are unknown yet. The typical Guillain-Barre syndrome could be diagnosed by the patient's syndroms and physical exams as the rapid onset of weakness, paralysis and loss of reflexes. The analysis of CSF and electrical test of nerve and muscle function can be performed to confirm the diagnosis. Most of the cases usually occur shortly after a viral infection. Method & Result : This is the clinical report about the one patient daignosed as Guillain-Barre syndrome. The patient, 9-year-old girl had the hemiparesis after upper respiratory infection. We characterized her as Wei syndrom(?證). The patient was treated by acupunture, indirect moxibustion, herb medication(通竅湯 加味方, 四物湯合檳蘇散 加味方) and had significant improvement in the Wei syndrome(?證). Conclusion : We report that we had good effects of oriental medical treatment on Guillain-Barre syndrome.

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A case of the patient with Wei symptom suspected Guillain-Barre syndrome (Guillain-Barre syndrome으로 추정되는 계증 치험 1례(例))

  • Jeong, Byoung-Mu;Sin, Won-Yong;Choi, En-Young;Yoon, Cheol-Ho;Jeong, Ji-Cheon;Hyun, Min-Kyung
    • The Journal of Internal Korean Medicine
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    • v.25 no.4
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    • pp.450-456
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    • 2004
  • Guillain-Barre syndrome, or acute inflammatory polyneuritis, is a disorder in which the body's immune system attacks parts of the peripheral nervous system. The causes and mechanisms of this syndrome are unknown. Typically, Guillain-Barre syndrome can be diagnosed from the patient's symptoms and physical examination such as the rapid onset of weakness, paralysis and loss of reflexes. The analysis of CSF and electrical tests on nerve and muscle function can be performed to confirm the diagnosis. Most cases occur shortly after a viral infection. This is a clinical report about one patient suspected as having Guillain-Barre syndrome. The patient, a 62-year-old man had weakness in both legs after gastroduodenal disease. His weakness and general condition improved after Korean medical treatments, so this is reported as a potential treatment.

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Review on Wei Symptom in General with this Rare Clinical Study on 1case of Patient with Wei symptom Finally Dianosed as Guillain-Barre Syndrome and Whether Distinction should be Made in Treatment and Categorizating in Clinical Aspect (길리안 바레 증후군으로 최종 진단된 위증 환자의 고찰 1례와 이를 통한 위증 질환의 범주 책정 및 치료의 차등성 여부에 대한 논의)

  • Lee, Seung-Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.1
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    • pp.298-302
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    • 2007
  • To see whether this rare clinical case of patient with guillain Barre syndrome which is a type of acute inflammatory demyelinating polyneuropathy could provide further insight in categorizing Wei symptom(위증) in general. To treat Wei symptom(위증) using traditional herbal medicine Bojoongikgi-tangkami(補中益氣湯加味) and electronic acupuncture applied on the yangmyung channel(陽明經) selected in the Yellow Emperor's of internal medicine and on Panggwang chanel considered as painful lesion. There was significant improvement in motor grade of patient in spite of the period it took to recover and there was sequoia left behind as well. The basic concept of ‘treating yangmyung channel(陽明經) most of all(獨取陽明)’ is emphasized in treatment of Wei symptom(위증) and contains nourishment of middle warmer energy(補中益氣), clear yangmyung(淸化陽明).