• Title/Summary/Keyword: acute effect

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May Low Level Laser Therapy be the Candidate of First Choice for the Acute Stroke? (중풍 급성기에 있어서 레이저치료에 대한 최신지견 고찰 : 임상 논문을 중심으로)

  • Yang, Chang-Sop;Jang, In-Soo;Sun, Seung-Ho
    • The Journal of Internal Korean Medicine
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    • v.31 no.3
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    • pp.612-619
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    • 2010
  • Background : Low level laser therapy may be an effective method to protect tissue damage in acute stroke. Recently, series of clinical studies on the basis of animal experiments report efficacy and safety of laser therapy at early stages of acute stroke. Laser promotes mitochondrial ATP synthesis to reduce cell death by ischemic infarction. Objectives : To report possibility of non-invasive laser therapy for acute stroke by reviewing literature about its effectiveness, safety and mechanism. Methods : We searched papers using PubMed and 'Web of Knowledge' of Thomson ISI, using the keywords "Laser Therapy, Low-Level" and "Stroke". Limitations were last 10 years of publications and only in English. Search range includes RCTs, clinical reports, reviews and animal experiments. Papers not matched with inclusion criteria were excluded. Results : A total 223 studies were found, 203 excluded during title and extract screening. After scanning 20 papers the final 2 serial RCTs were selected and analyzed. They reported that transcranial laser therapy led in neuroprotective effect for acute stroke patents. Clinical evaluation factors showed favorable trend and initial safety. Conclusions : Non-invasive laser secured safety of clinical application. It may be a favorable choice for the acute stage of stroke.

Case Report of Sinsimtong with The Acute Glomerulonephritis Patient (신심통(腎心痛)으로 변증된 급성 사구체 신염 환자 치험 1례)

  • Cho, Gook-Ryung;Jung, Jong-An;Kim, Nam-Uk;Hong, Seok;Jung, Min-Young;Wi, Jun;Jeon, Sang-Yun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.22 no.1
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    • pp.212-215
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    • 2008
  • This study was designed to evaluate of oriental treatment on the sinsimtong With Acute glomerulonephritis Patient. We used oriental treatment for a patient who have the sinsimtong which has been caused by the Acute glomerulonephritis. After treated with oriental treatment, the symptoms of the Acute glomerulonephritis are disappeared. Form the above result, it could be suggest that oriental treatment have good effect on the sinsimtong With Acute glomerulonephritis Patient.

Design of Moir${\acute{e}}$- and Starburst-Free Metal Meshes for Touch Screen Panels (모아레, 스타버스트 현상이 없는 터치스크린 패널용 메탈 메쉬 설계)

  • Shin, Dong-Kyun;Park, Jong-Woon;Seo, Hwa-Il
    • Journal of the Semiconductor & Display Technology
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    • v.13 no.1
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    • pp.83-90
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    • 2014
  • Using a ray tracing simulation, we have investigated the moir${\acute{e}}$ and starburst phenomena of touch screen panels (TSPs) based on opaque metallic grids (square, hexagonal, and random grids). It is demonstrated that employing a random metal mesh is the most effective way to suppress the moir${\acute{e}}$ and starburst phenomena at the same time. At high crossing angles between metal mesh of TSPs and black matrix (BM) of displays, however, a random metal mesh brings in stronger moir${\acute{e}}$ phenomenon than a square metal mesh due to point defects. Though the square metal mesh suppresses the moir${\acute{e}}$ effect substantially at high crossing angles, yet it results in the strongest starburst patterns. We have also provided the simulation scheme that can capture the moir${\acute{e}}$ and starburst patterns observed experimentally and useful design guidelines for metal grids.

The Effect of Acute Coagulopathy in Profoundly Traumatic Patients on Acute and Early Deaths (고도 중증외상 환자에서 급성 혈액응고장애가 초기 및 조기 사망에 미치는 영향)

  • Noh, Minsu;Yang, Song-Soo;Kyoung, Kyu-Hyouck
    • Journal of Trauma and Injury
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    • v.27 no.4
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    • pp.158-164
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    • 2014
  • Purpose: Numerous studies have investigated the pattern of traumatic death with a focus on the injury mechanism, the severity of the injury and the presence of hemorrhage. Acute coagulopathy has been treated as only one of many complications. The purpose of this study was to investigate the influence of acute coagulopathy on acute and early death due to trauma. Methods: A retrospective analysis of trauma patients with injury severity score (ISS)${\geq}25$ who had been treated between January 2011 and December 2012 was conducted. Based on the time of injury, traumatic death was categorized into acute (within 48 hours) and early (from 3 to 7 days). The correlations between various parameters within 24 hours after injury and time of death were analyzed. Results: A total of 124 patients were enrolled. Of them, 8.1% (n=10) of the patients experienced acute mortality. For those patients, significant differences in initial systolic blood pressure, coagulopathy score, amount of transfusion, abbreviated injury scale of the head and neck, the abdomen and the extremities were noted. Early mortality was experienced by 7.0% (n=8) of the patients, only coagulopathy score was found to be a significant independent risk factor for acute (odds ratio: 3.127; 95% confidence interval: 1.185-8.252; p=0.021) and early mortality (odds ratio: 2.470; 95% confidence interval: 1.029-5.929; p=0.043). Conclusion: Acute traumatic coagulopathy has an important role in the mortality, even after the acute phase. Early management and prevention of acute coagulopathy may improve survival of trauma patients.

Therapeutic Effect of 30 Cases of Scalp and Do-ma Acupuncture Related with Governor Vessel(Dok) and Bladder Meridian(Chok-taeyang) on Acute Low Back Pain (급성(急性) 요부(腰部) 염좌(捻挫) 환자 30례(例)의 두부(頭部) 독맥경(督脈經), 족태양방광경(足太陽膀胱經) 경혈(經穴) 도마침법(倒馬鍼法) 치료효능에 대한 임상적(臨床的) 고찰(考察))

  • Kang, Min-Wan;Kim, Sung-Lae;Choi, Ka-Wan;Song, Hyong-Gun;Kim, Jeong-Ho;Yang, Ki-Young;Yim, Yun-Kyoung;Hong, Kwon-Eui;Lee, Hyeon;Kim, Young-Il
    • Journal of Acupuncture Research
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    • v.23 no.3
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    • pp.207-214
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    • 2006
  • Objectives : This study is designed in order to evaluate the therapeutic effect of Scalp Acupuncture and Do-ma Acupuncture related with Governer Vessel(Dok) and Bladder Meridian(Chok-taeyang) on acute low back pain Methods : We investigated 30 patients suffering from acute low back pain were admitted to Dunsan O.M.hospital from March. 1st 2005 to December. 30th 2005. We divided into two groups: one group was treated with Scalp acupunture, another group was treated with common acupuncture. 30 patients, were diagnosed only straightened curvature on lateral view of lumbar spine X -ray. Scalp acupunture related with Governer Vessel(Dok) and Bladder Meridian(Chok-taeyang) and Do-ma acupuncture. To estimate the efficacy of treatment that applied for two groups, we compared the visual analog scale(VAS), Oswestry disabiliby index(ODI) and Straight Leg Raising Test(SLRT) score of two groups statistically. Results : Both Scalp acupuncture related with Governer Vessel(Dok) and Bladder Meridian (Chok-taeyang) and Do-ma acupuncture therapy showed good effect on acute low back pain. It was proved by the difference between VAS, ODI and SLRT score checked before treatment and what checked after treatment on each groups. Conclusion: The therapeutic effect of Scalp Acupuncture and Do-ma Acupuncture on acute low back pain can be recommended as a useful therapy to treat acute low back pain.

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Anti-Inflammatory Effect of Haepyoejin-tang plus Antler water extract in Xylene-Application Mouse Ear Acute Inflammation Model (해표이진탕가녹용(解表二陳湯加鹿茸)이 Xylene으로 유발된 마우스의 급성 염증에 미치는 영향)

  • Jung, Bong-Gyun;Jeon, Kwi-Ok;Park, Mee-Yeon;Choi, Hae-Yun;Kim, Jong-Dae;Cho, Dong-Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.4
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    • pp.985-991
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    • 2006
  • In the present study, the anti-inflammatory effect of Haepyoeiin-tang plus Antler water extract water extract was tested in Xylene-Application mouse ear acute inflammation model. The test articles were once dosed before Xylene-Application, and the changes on Dody weight and weights and histopathological observation of induced ear were conducted with ear histomorphometry, The increases of absolute and relative ear weight detected in vehicle control compared to that of sham, were significantly and dose-dependently inhibited by Haepyoejin-tang plus Antler in the present study, A classic acute inflammatory histological changes such as subcutaneous edema, hypertrophy and infiltration of inflammatory cells, was detected in vehicle control. However, these histological changes were significantly and dose-dependently inhibited by Haepyoeiin-tang plus Antler. In addition, the increases of ear thickness half and thickness full detected in the vehicle control, were also dose-dependently decreased in the all Haepyoeiin-tang plus Antler-dosing groups. Base on these results, it is concluded that Haepyoeiin-tang plus Antler water extracts have a clear anti-inflammatory effect on the acute inflammation. However, somewhat lower anti-inflammatory effects were detected in Haepyoeiin-tang plus Antler water extracts compare to that of Dethamethason and Dicrofenac. About 500 mg/kg of Haepyoeiin-tang plus Antler water extracts have similar effect compared to that of Dicrofenac 15 mg/kg.

Anti-Inflammatory Effect of 'Jungcheonhwadamgangki-tang'in Xylene-Application Mouse Ear Acute Inflammation Model (정서화담강기탕(定瑞化痰降氣湯)이 Xylene으로 유발된 마우스의 급성 염증에 미치는 영향)

  • Song, Muh-Sik;Jeon, Kwi-Ok;Park, Mee-Yeon;Choi, Hae-Yun;Kim, Jong-Dae;Cho, Dong-Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.20 no.4
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    • pp.875-881
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    • 2006
  • In the present study, the anti-inflammatory effect of 'Jungcheonhwadamgangki -tang' water extract was tested in Xylene-Application mouse ear acute inflammation model. The test articles were once dosed before Xylene-Application, and the changes on body weight and ear weights and histopathological observation of induced ear were conducted with ear histomorphometry. The increases of absolute and relative ear weight detected in vehicle control compared to that of sham , were significantly and dose-dependently inhibited by Jungcheonhwadarn -gangki-tang in the present study. A classic acute inflammatory histological changes such as subcutaneous edema, hypertrophy and infiltration of inflammatory cells, was detected in vehicle control. However, these histological changes were significantly and dose-dependently inhibited by Jungcheonhwadam-gangki-tang. In addition, the increases of ear thickness half and thickness full detected in the vehicle control, were also dose-dependently decreased in the all Jungcheonhwadamgangki-tang-dosing groups. Base on these results, it is concluded that Jungcheonhwadamgangki-tang water extracts have clear anti-inflammatory effect on the acute inflammation, and about 500 mg/kg of Jungcheonhwadamgangki-tang water extracts have similar effect compared to that of Dicrofenac 15 mg/kg.

Egg phospholipids exert an inhibitory effect on intestinal cholesterol absorption in mice

  • Lee, Yoojin;Han, Catherine Y.;Bae, Minkyung;Park, Young-Ki;Lee, Ji-Young
    • Nutrition Research and Practice
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    • v.13 no.4
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    • pp.295-301
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    • 2019
  • BACKGROUND/OBJECTIVES: Consumption of cholesterol-rich foods, such as eggs, has a minimal effect on circulating cholesterol levels in healthy humans. To gain insight, we investigated whether phospholipids rich in eggs (EPL) interfere with intestinal cholesterol absorption in vivo. MATERIALS/METHODS: To investigate the acute effect of EPL on intestinal cholesterol absorption, male C57BL/6J mice were orally administered with 6, 11, or 19 mg of EPL for three days. We also tested the effect of chronic EPL consumption on cholesterol metabolism in the small intestine and the liver in mice with diet-induced hypercholesterolemia. Male C57BL/6J mice were fed a high fat/high cholesterol (HF/HC; 35% fat, 0.25% cholesterol, w/w) diet for 4 weeks to induce hypercholesterolemia, and subsequently the mice were either fed 0, 0.4 or 0.8% (w/w) of EPL for 6 weeks. RESULTS: Intestinal cholesterol absorption was significantly decreased by the highest dose of acute EPL administration compared to control. Chronic EPL supplementation did not significantly alter intestinal cholesterol absorption nor plasma levels of total cholesterol and low-density lipoprotein cholesterol. In the small intestine and the liver, EPL supplementation minimally altered the expression of genes which regulate cellular cholesterol levels. CONCLUSION: Although chronic EPL consumption was not able to counteract hypercholesterolemia in HF/HC-fed mice, acute EPL administration decreased intestinal cholesterol absorption. This study provides in vivo evidence that acute administration of PLs in eggs prevent cholesterol absorption in the intestine, suggesting a mechanism for a minimal effect of egg consumption on circulating cholesterol levels.

The Comparative Study on the Effect of Acupuncture Treatment with or without Indirect Moxibustion Treatment for Acute Ankle Sprain (급성 족관절 염좌에 대한 침구병행 치료와 침 단독 치료 효과의 비교 연구)

  • Woo, Chang-Hoon;Kwon, O-Gon;An, Hee-Duk
    • Journal of Korean Medicine Rehabilitation
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    • v.20 no.1
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    • pp.141-152
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    • 2010
  • Objectives : The purpose of this study is to compare with the effect of acupuncture treatment with or without indirect moxibustion treatment for acute ankle sprain. Methods : This study was carried out on the 48 patients who had been treated for acute ankle sprain from June 1st to November 30th 2009 in the Dept. of Oriental Rehabilitation, Pohang Oriental Medical Hospital, Daegu Hanny University. The patients were divided into 3 groups ; Group A took near acupuncture point_needling, Group B took remote acupuncture point needling, Group C took remote acupuncture point needling with indirect moxibustion. 3 Groups had been co-treated with rest, ice, compression and elevation(RICE) therapy, physical treatment and administered Ojeok-san(Wuji-san) extract granule. To evaluating the efficiency of each treatment, Ankle-Hindfoot Scale(AHS) and Visual Analogue Scale(VAS) were applied before treatment and after 3rd treatment. Results : In results, the AHS scores were increased and the VAS scores were decreased after 3rd treatment in all group. Also, AHS scores and the VAS scores of intergroup were showed no significant change. Conclusions : In this study, there is no significant effect between only acupuncture treatment and moxibustion co-treatment for acute ankle sprain.

The Effect of Combined Acupuncture Treatment on Acute Ankle Sprain: Case Series (급성 족관절 염좌에 대한 복합 침치료의 효과: 사례군 연구)

  • Cho, Nam-Hoon;Kim, Mi-Riong;Jeong, Hoon;Kim, Dong-Sub;Kim, Eun-Soo;Park, Ji-Yong;Park, Hyun-Min;Lee, Jin-Ho;Ha, In-Hyuk
    • Journal of Korean Medicine Rehabilitation
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    • v.24 no.1
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    • pp.119-123
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    • 2014
  • The purpose of this study is to report the effect of combined acupuncture treatment on acute ankle sprain patients. The subjects included in this study were 15 acute ankle sprain patients who visited Jaseng Hospital of Korean Medicine from Oct. 15th, 2012 to Feb. 8th, 2013. We treated 15 patients with combined acupuncture treatment. The treatment consisted of Hwangrunhaedok-tang (Huanglianjiedutang) pharmacupuncture, electroacupuncture (applied to GB39, ST36 on the affected side), acupuncture (applied to TE17, SI6 on the unaffected side with Dong-Qi therapy). To assess the effect of treatment, the numeric rating scale (NRS) was applied before and after treatment. After first combined acupuncture treatment, the NRS scores significantly decreased from $8.33{\pm}0.94$ to $2.26{\pm}0.44$ (p<0.01). We suggested that Combined acupuncture treatment are effective and useful on acute ankle sprain. And, further studies will be needed.