• Korean Journal of Acupuncture
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• 제27권3호
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• pp.97-108
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• 2010

Background : The location of acupoints on rat, which may differ from that of human body due to anatomical structure, is defined variously among researchers, which may cause the problem of low repeatability and objectivity. Design : The measurement of hind limb consist of measuring the distance between knee joint and tibia tubercle in order to set the knee joint as common criteria. Based on it, the three mostly referred location of ST36 were represented with the knee joint as a datum point and compared. The electroacupuncture stimulation was administrated after the abdominal pain was induced by acetic acid. And the analgesic activity of each ST36 acupoint was evaluated by measuring the number of writhing reflex, in order to observe the differences of treatment effect in accordance with the location of ST36 acupoints. Results : The result of measurement confirmed the differences in the acupoint location of ST36 among researchers. The writhing reflex test using the acetic acid-induced abdominal pain stimulated with electroacupuncture of 100Hz showed that there were statistically significant differences in the analgesic effect between control group and three ST36 groups (P<0.05). However there were no differences observed among three mostly referred location of ST36 acupoints (P>0.05). Conclusions : We recommend "the point located 6.5 mm below the knee joint at the anterior tibial muscle" as a standard ST36 acupoint location qualified by the WHO Standard Acupuncture Point Locations in 2008.

• Journal of Acupuncture Research
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• 제27권2호
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• pp.143-154
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• 2010

Objectives : The main purpose of this research is to make a survey of the effective way of the Oriental medical care and to enlarge the range of Oriental medical treatment about neck pain patients caused by traffic accident. Methods : In following research. we surveyed 197 neck pain patients of traffic accident who admitted in Daegu Hanny University Oriental Medical Hospital from May, 1, 2008 to september, 30, 2009 according to medical chart. Results : 1. In distribution of gender and age, the rate of female was 74.6%, that of male was 25.4% and the majority of the patients were thirties. In results of treatment according to gender and age, the effective rate of female was higher than the male. that of teens was highest. 2. In total results of treatment, the highest distribution was fair with 40.1%, the effective rate was 90.9%. 3. In category of traffic accident patterns, the highest distribution was car to car crash with 81.7%. The results of treatment according to the significance test were shown statistical significance. 4. In admission days, the highest distribution was 6~10 days with 41.1%. The highest effective rate was 21~25days with 100%. The results of treatment according to the significance test were shown statistical significance. Conclusions : This study suggested that Oriental medical treatments are effective in patients of neck pain caused by traffic accident. Further studies are needed for progress report that after accident patients are discharged from the Oriental Medical Hospital.

• 여성건강간호학회지
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• 제9권2호
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• pp.128-137
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• 2003

The purpose of this study was to identify effects of the SP-6 acupressure on dysmenorrhea, skin temperature at th e CV2 acupoint. This study was a pretest-post test study design wit h a nonequivalent control group. Data were collected from May 1 to August 31, 2002. A total of 58 female student s from two universities participated in the study. Among them, 30 female students were assigned as the experimental group an d the other 28 students to the control group. Both groups were pretested before the intervention for three variables, the degree of dysmenorrhea, and skin temperature at the CV2 acupoint. Then, the SP-6 acupressure was provided for 20 minutes for students in the experimental group. The instruments used in this study included the Visual Analogue Scale developed by Johnson(1974), skin thermometer by Simson Eectric CO., Menstrual Attitudes Questionnaire Scale developed by Brooks-Gunn & Ruble(1980), and Stress scale developed by Chun and Kim(1990). The data were analyzed with the SAS program using Chi-square test, t-test, and ANCOVA and Bonferroni method were used to determine significant differences between the two groups. The results of this study are as follows ; 1. There was a statistically significant difference in the intensity of dysmenorrhea after the intervention with the experimental group having a lower intensity than the control group. 2. There was a statistically significant difference in skin temperature at the CV2 acupoint 30min (F=4.87, p=0.03) after the intervention with the experimental group having a higher temperature. In conclusion, the SP-6 acupressure has proved to be an effective nursing intervention to reduce dysmenorrhea. Therefore, it is recommended women suffering from dysmenorrhea use the SP-6 acupressure.

• Journal of Acupuncture Research
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• 제32권1호
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• pp.109-118
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• 2015

Objectives : This study aimed to investigate the correlation between fear-avoidance beliefs and neck pain/neck disability caused by traffic accidents. Methods : We surveyed 52 patients who were injured in traffic accidents. The patients completed baseline measures of pain, disability, fear-avoidance beliefs according to the visual analogue scale(VAS), neck disability index(NDI) and a fear-avoidance beliefs questionnaire (FABQ). At the end of medical treatment, VAS and NDI were reassessed. In order to determine the relationship between FABQ(including its subscales), change of VAS and NDI, Pearson correlation coefficients were used. To examine the accuracy of previously reported cut-off scores, we classified the patients into low and high groups and analyzed the change of VAS and NDI. The relationship was measured by Mann-Whitney U-test and a student's T-test. Results : FABQ and its subscales(total, physical activity and work) were significantly correlated with final VAS and NDI. FABQ-T showed low significant negative correlation with change of NDI. Previously reported cut-off scores did not show a statistical significance in this study Conclusions : This study suggests that screening for fear-avoidance beliefs may be useful for identifying patients at risk of prolonged pain after traffic accidents.

• Korean Journal of Acupuncture
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• 제31권4호
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• pp.195-207
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• 2014

Objectives : The purpose of this study is to examine the effects of laser acupuncture according to the wavelength(532 nm, 650 nm, 830 nm, 904 nm, and 1064 nm) at the acupoint of GB34 GB39 on neuropathic pain rat induced by tibial and sural nerve transection(TST). Methods : Neuropathic pain in rats was induced by tibial nerve and sural nerve transection. The rats were divided into the intact group, the TST control group, and the laser acupuncture therapy group. The laser acupuncture therapy groups were then divided into subgroups with 532 nm(L532), 650 nm(L650), 830 nm(L830), 904 nm(L904), and 1064 nm(L1064) laser acupuncture therapy. The acupoint of GB34 GB39 was selected, and laser acupuncture therapy was provided on both sides alternatively twice a week in a total of 6 sessions. Results : All the laser acupuncture groups showed a significant decrease in reaction time and force intensity. L532, L904, and L1064 groups showed a significant decrease in Bax, the L532 group showed a significant increase in Bcl-2, L532 and L1064 groups showed a significant decrease in the Bax/Bcl-2 ratio, and L532 and L650 groups showed a significant increase in mGluR5, as compared with the TST control group, among nerve tissue reaction. Conclusions : These results showed that laser acupuncture therapy at each of the wavelengths had some significance on neuropathic pain.

• 한국임상수의학회지
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• 제18권4호
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• pp.368-373
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• 2001

To study the immunomodulatory effect of aquapuncture with canine parvovirus killed vaccine, the vaccine was inoculated into the dogs twice with on 2-week interval. The 6 dogs in the experimental group were inoculated through the Jiao-Chao acupoint, and 5 dogs in the control group were done subcutaneously. The antibody titer was determined by the hemagglutination inhibition test. The HI titers of the experimental group showed significantly higher on days 21 and 28 than those of the control group. The biochemical test on serum total protein, protein fractions and the A/G ration showed a slightly increased in $\gamma$-globulin on days 21 and 28. The hematological findings on total leukocytes and differential counts showed no significance. It was thought that the aquapuncture of the canine parvovirus killed vaccine through the Jiao-Cho acupoint may stimulate the antibody production.

• Korean Journal of Acupuncture
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• 제20권3호
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• pp.29-34
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• 2003

Objectives : The purpose of this study was to investigate the Effect of Acupuncture Chok-samni(ST36) on Skin temperature(ST), Galvanic skin response(GSR) and Heart rate(HR) in humans. ST36 is used in uneasiness, high fever, stroke, paralysis on oriental medicine. Methods : Subjects were 18 healthy oriental medical students volunteers(15male, 3female, mean age-28). Under sequence of ST36 acupuncture, the first group was observed ST, the second group was observed GSR and the third group was observed HR. Skin temperature was measured on Haegye acupoint(ST41) before and after acupuncture stimulation. Each test took 15minutes. This test was performed twice in order to increase the statistical authenticity. Results : Our result indicates that acupuncture stimulation of ST36 statistically decreased skin temperature on ST41. Also statistically decreased in HR. The change of GSR after ST36 acupuncture was decreased, but there is no statistical. Conclusions : These results suggested that acupuncture stimulation of ST 36 has effect on ST and HR in human body, and may be used by treatment as control the nerve system.

• Korean Journal of Acupuncture
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• 제24권4호
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• pp.151-162
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• 2007

Objectives : The purpose of this study was to examine the anti-allergic effect in vivo, and to observe single toxicity in mice of Armeniacae Semen herbal acupuncture solution (ASHA). Methods : We investigated anti DNP IgE-mediated passive cutaneous anaphylaxis in rodents and compound 48/80-induced active systemic anaphylatic shock in mice after treatment at both BL13 with ASHA of 25 ${\mu}{\ell}$(mice) or 50 ${\mu}{\ell}$(rats) 3 times for 5 days. To ascertain safety and toxicity of ASHA, we examined single toxicity test. In single test, three groups were treated with different dosages of ASHA (ASHA250, ASHA500 and ASHA1000) according to on Korean Food and Drug Administration, respectively. We observed attentively motality, abnormal clinical sign, body weight change, and organ weight of mice after ASHA treatment. Results : ASHA inhibited passive cutaneous anaphylaxis and active systemic anaphylatic shock by oral administration. During toxicity experiment period, there was no difference in body weight change, and organ weight among different dose groups. Death were not found in single test i.p. group. (ASHA250, ASHA500 and ASHA1000). Several individuals of single test i.p. group were observed yellow brown discharge around anus in early period after administration. Conclusions : These results indicate that ASHA have inhibition effects on passive cutaneous anaphylaxis and active systemic anaphylatic shock, and suggest that has some toxicity in high dosage.

• Korean Journal of Acupuncture
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• 제26권2호
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• pp.75-89
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• 2009

Objectives: Warm needling combines simultaneously the effects of acupuncture and moxibustion. This study was to investigate whether warm needling could relieve acute knee arthritis induced by carrageenan in rats. Methods: To illuminate the underlying mechanisms of the warm needling-induced antinociception, weight bearing force (WBF) was observed on the acute knee arthritic rat model. Under general anesthesia, ST36, SP9, Hakjung extra point, LI4 were punctured and stimulated with 30 mg moxa ball combustion on top of the needle (${\emptyset}0.18{\times}8mm$). Results: In behavioral test, rats subsequently showed a reduced stepping force of the affected limb 3 hours after the induction of arthritis. Warm needling on the contralateral or ipsilateral ST36 failed to show antinociceptive effect on the acute knee arthritis. Warm needling on the contralateral SP9 or LI4 increased WBF values to normal level in the acute stage of the arthritis. Warm needling on the Hakjung extra-point resulted in the significant antinociceptive effects through acute stage. These effects of warm needling were suppressed by opioids receptor antagonist naltrexone (10 mg/kg, i.p.) and alpha adrenoceptor antagonist phentolamine (5 mg/kg, i.p.). Conclusion: The data suggest that warm needling-induced antinociception is differently mediated by acupoints and accomplished by activating the descending inhibitory systems including endogenous opioids and $\alpha$-adrenoceptors.

• Journal of Acupuncture Research
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• 제33권2호
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• pp.97-108
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• 2016

Objectives : This study was performed to investigate the analgesic effect of Styrax japonica pharmacopuncture on formalin induced pain in rats and to figure out efficient extraction method. Methods : The subjects were divided into 5 groups ; normal group(treated with normal saline at KI03, and injected normal saline at right hindpaw after 35 minutes), control group(treated with normal saline at KI03, and injected with formalin at right hindpaw after 35 minutes), water group(treated by hot water extraction pharmacopuncture at KI03, and injected with formalin at right hindpaw after 35 minutes), ethanol group(treated with ethanol extraction pharmacopuncture at KI03, and injected with formalin at right hindpaw after 35 minutes), and ultrasound group(treated with ultrasound extraction pharmacacupuncture and injected with fromalin formalin at right hindpaw after 35 minutes). We conducted a formalin test with ultrasonic vocalization( USV), and after the test checked for substance P, Aspartate aminotransferase(AST), and Alanine aminotransferase(ALT) concentration in the blood for each of the groups. Results : There was a significant analgesic effect of Styrax japonica pharmacopuncture in the early phase of the formalin test, and pharmacopuncture made with an ultrasound extracting method was observed to have a better analgesic effect than other extracting methods in early phases. The substance P concentration decreased significantly in the Styrax japonica pharmacopuncture treated group and no difference was found in the AST and ALT concentration of each group. Conclusion : These results demonstrated that Styrax japonica pharmacopuncture had analgesic effects in noxious nociceptors stimulation. Also pharmacopuncture made with an ultrasound extracting method had a better analgesic effect than others.