• International Journal of Computer Science & Network Security
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• v.22 no.5
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• pp.127-134
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• 2022

Generally developed for medical testing, electrocardiogram (ECG) recordings seizure the cardiac electrical signals from the surface of the body. ECG study can consequently be a vital first step to support analyze, comprehend, and expect cardiac ailments accountable for 31% of deaths globally. Different tools are used to analyze ECG signals based on computational methods, and explicitly machine learning method. In all abovementioned computational simulations are prevailing tools for cataloging and clustering. This review demonstrates the different effective methods for heart disease based on computational methods for ECG analysis. The accuracy in machine learning and three-dimensional computer simulations, among medical inferences and contributions to medical developments. In the first part the classification and the methods developed to get data and cataloging between standard and abnormal cardiac activity. The second part emphases on patient analysis from entire ECG recordings due to different kind of diseases present. The last part represents the application of wearable devices and interpretation of computer simulated results. Conclusively, the discussion part plans the challenges of ECG investigation and offers a serious valuation of the approaches offered. Different approaches described in this review are a sturdy asset for medicinal encounters and their transformation to the medical world can lead to auspicious developments.

• Applied Microscopy
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• v.52
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• pp.9.1-9.5
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• 2022

The compact smooth muscle 10S myosin II is a type of a monomer with folded tail and the heads bending back to interact with each other. This inactivated form is associated with regulatory and enzymatic activities affecting myosin processivity with actin filaments as well as ATPase activity. Phosphorylation by RLC can however, shuttle myosin from the inhibited 10S state to an activated 6S state, dictating the equilibrium. Multiple studies contributed by TEM have provided insights in the structural understanding of the 10S form. However, it is only recently that the true potential of Cryo-EM in deciphering the intramolecular interactions of 10S myosin state has been realized. This has led to an influx of new revelations on the 10S inactivation, unfolding mechanism and association in various diseases. This study reviews the gradual development in the structural interpretation of 10S species from TEM to Cryo-EM era. Furthermore, we discuss the utility of Cryo-EM in future myosin 10S studies and its contribution to human health.

• East Asian Journal of Business Economics (EAJBE)
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• v.10 no.1
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• pp.71-81
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• 2022

Purpose - Foodservice production is predominantly susceptible to rampant calamities since it trusts on social gatherings and interactions. This research aims to elaborate a brief framework of the literature review on the research conducted for the Coronavirus outburst regarding the food service sector. Research design, Data, and methodology - The method used in research involving interpretation of the subject content in a text data through a systematic process of classification to identify the themes and coding is referred to as the qualitative content analysis. It can also be defined as a useful research approach method of analysis instead of an empirical analysis. Result - Based on ultimate systematic literature analysis, the author figured out that the vendors should be given importance to the digital traveling interventions as the shortest factor in foodservice processing firms. Designing new sources of revenue and implementing numerous canceled regulations are other resolution that helps challenges in food service industries Conclusion - The Coronavirus pandemic has affected the foodservice business leading to the permanent closure of some businesses. There is a need for a stimulus package from the state to revive these businesses since they play a great role in the economy's growth and are regarded as part of the economy, and most of their activity is undocumented.

• Biomolecules & Therapeutics
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• v.32 no.4
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• pp.492-498
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• 2024

Bioassay and HPLC-UV guided fractionations of the crude extract of marine-derived Streptomyces sp. SNA-077 have led to the isolation of a red pigment, undecylprodigiosin (1). The chemical structure of undecylprodigiosin (1) was revealed by the interpretation of NMR and mass spectroscopic (MS) data. Further, anti-melanogenic effects of undecylprodigiosin (1) were investigated. First, the melanin contents of undecylprodigiosin (1)-treated B16 cells were evaluated. Furthermore, undecylprodigiosin (1) significantly inhibited the key enzymes involved in melanogenesis, including tyrosinase, tyrosinase related protein-1 (TYRP-1), and dopachrome tautomerase (DCT). The mRNA and protein expression levels of Microphthalmia-associated transcriptian factor (MiTF), a critical transcription factor for tyrosinase gene expression, were also suppressed by undecylprodigiosin (1) treatment in B16 analyses. Collectively, our results suggest for the first time that undecylprodigiosin (1), a potent component isolated from an extract of marine Streptomyces sp. SNA-077, critically exerts the anti-melanogenic ability for melanin synthesis.

• The korean journal of orthodontics
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• v.36 no.3 s.116
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• pp.218-227
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• 2006

Although the submentovertex radiograph and surface EMG are not often used due to the difficulty of interpretation, they are accepted as useful diagnostic and analytic aids for skeletal asymmetry. There have been reports which state that they were also useful for the evaluation of vertical skeletal relations. The purpose of this study was to evaluate the correlations between EMG data, measurements from submentovertex radiographs, facial types and facial asymmetry following examination of 60 asymmetric patients. The radiographic corpus length were greater in the nonaffected sides (p<0.001), gonion to interspinosum axis were greater in the affected sides and the mandibular condyle and gonion were located more anteriorly in the non-affected sides than in the affected sides but not significant (p=0.07). The activity of the anterior temporal muscle in rest position was higher in the affected sides than in the non-affected sides (p<0.01). The activity of the masseter muscle at maximum clenching was found to be nonsignificant but it was higher in the affected sides than in the non-affected sides (p=0.09). There was positive correlation between facial index and the intercondylar axes angle (p<0.01). There was positive correlation between masseter muscle activity in maximum occlusion and facial index in the affected and non-affected sides (p<0.05). The results demonstrate that the submentovertex radiograph and EMG can provide useful information for the evaluation of horizontal and vertical skeletal relations.

• Journal of the Korean Chemical Society
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• v.39 no.4
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• pp.244-251
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• 1995

The palladium(II) complexes(where, [Pd(L)2X2], L=isoxazole(isox), 3,5-dimethylisoxazole(3,5-diMeisox), 3-methyl, 5-phenylisoxazole(3-Me, 5-Phisox), and 4-amino, 3,5-dimethylisoxazole(4-ADI); X=Cl, Br] with isoxazole and its derivatives are investigated on antitumor activity by EHMO calculation. It is found that the net charge of the two halogen atoms in trans-isomers are greater than those in cis-ones, indicating that ionic character of Pd-X bond in trans-isomers is greater than that of cis-ones, and so dissociation of Cl- ion is easier than that of Br- ion in aqueous solution in body. Furthermore, it is found that the ${\sigma}MO$ energy of Pd(dx2-y2)-X(px) bond $(E{\sigma}(Pd-X))$ is higher than that of Pd(dx2-y2)-N(px) bond $(E{\sigma}(Pd-N))$ without exception, about all the complexes, and also the $E{\sigma}(Pd-X)$ of trans-isomers is higher than that of cis-isomers. From the above facts, the degree of dissociation in Pd-X bond would be related to antitumor activity. In fact, the linear equation of correlation coefficient 0.96 is fairly established between ${\Delta}E{\sigma}(N-X)(E\sigma(Pd-N)－E{\sigma}(Pd-X))$ and inhibitory activity coefficient, logIA.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.11 no.4
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• pp.149-165
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• 2016

The objectives of this study is to assess the influence of individual characteristics and economic environment on the entrepreneurship such as entrepreneurial Intention and behavior based on the theory of Planned behaviors. This study used a country-level merged data set composed of GEM(Global Entrepreneurship Monitor) data and the OECD Statistics data. And this used the fixed effect model to analyze the panel data of 31 OECD countries during the period from 2005 to 2014. Our findings show that subjective norm has a significantly positive effect on entrepreneurial intention. In individual characteristics, the perceived opportunities has a significantly positive effect on early-stage entrepreneurial activity(TEA) and improvement-driven opportunity entrepreneurial activity. We identify the differences of between necessity-driven and improvement-driven opportunity entrepreneurial activity. For example, the effect on necessity-driven entrepreneurial activity is significantly negative. We also find the differences of between necessity-driven and improvement-driven opportunity entrepreneurial activity in economic environment variables. While real GDP growth as a demand variable has a significantly positive effect on necessity-driven entrepreneurial activity, unemployment rate as a supply variable has a significantly negative effect on early-stage entrepreneurial activity(TEA) and improvement-driven opportunity entrepreneurial activity. And GDP per capita as a supply variable has a significantly positive effect on early-stage entrepreneurial activity(TEA) and improvement-driven opportunity entrepreneurial activity. But the effect on necessity-driven entrepreneurial activity is significantly negative. We provide an interpretation of these empirical findings, emphasizing the importance of considering individual characteristics and economic environment simultaneously in promoting entrepreneurship.

• Economic and Environmental Geology
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• v.53 no.5
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• pp.585-596
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• 2020

The 2017 Pohang Earthquakes occurred near a drill site in the Pohang Enhanced Geothermal System. Water injected for well stimulation was believed to have reactivated the buried near-critically stressed Miocene faults by the accumulation of the Quaternary tectonic strain. However, surface expressions of the Quaternary tectonic activity had not been reported near the epicenter of the earthquakes before the site construction. Unusual, large-scale water-escaped structures were identified 4 km away from the epicenter during a post-seismic investigation. The water-escaped structures comprise Miocene mudstones injected into overlying Pleistocene coastal sediments that formed during Marine Isotope Stage 5. This indicates the vulnerable state of the mudstones long after deposition, resulted from the combined effects of rapid tectonic uplift (before significant diagenesis) and the development of an aquifer at their unconformable interface of the mudstone. Based on the detailed field analysis and consideration of all possible endogenic triggers, we interpreted the structures to have been formed by elevated pore pressures in the mudstones (thixotropy), triggered by cyclic ground motion during the earthquakes. This interpretation is strengthened by the presence of faults 400 m from the study area, which cut unconsolidated coastal sediment deposited after Marine Isotope Stage 5. Geological context, including high rates of tectonic uplift in SE Korea, paleo-seismological research on Quaternary faults near the study area, and historical records of paleoearthquakes in SE Korea, also support the interpretation. Thus, epicenter and surrounding areas of the 2017 Pohang Earthquake are considered as a paleoseismologically active area, and the causative fault of the 2017 Pohang Earthquakes was expected to be nearly critical state.

• Journal of Science Education
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• v.41 no.3
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• pp.318-333
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• 2017

In this study, we analyzed activities in life science chapters of middle school 'science' textbooks for the 2009 revised Korea national curriculum and examined the difference between the analysis based on scientific practices and the analysis based on inquiry skills. As a results, there was a lot of inquiry skills in the order of 'reasoning', 'observing', 'classification' in the all of grade. In scientific practices, 'data analysis and interpretation' and 'constructing explanations and devising problem solving' were biased. This shows that life science inquiry activities in middle school 'science' textbooks are lacking in diversity in scientific practice elements as well as inquiry skills, and that the goals of the activities are limited. In addition, through the interrelationships between scientific inquiry skills and scientific practice elements, we examined contents relevance in the transition from inquiry function center to scientific practice, and compared with the results of inquiry activities in textbook, The results of this study were matched monotonously due to the tendency to basic inquiry-data interpretation / basic inquiry-explanation. This comes from results of the lack of diversity in activities presented in middle school 'science' textbooks. In this study, it is suggested that efforts should be made to include diverse scientific practice elements in the process of realizing 2015 revised Korea national curriculum from the simple and diversity-less inquiry activity through analyzing the textbooks of the 2009 revised Korea national curriculum.

• The Journal of the Korea Contents Association
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• v.17 no.1
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• pp.701-717
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• 2017

Criticism is related with recognition activity which is interpreting and evaluating the text based on the particular criteria. It reflects the awareness system of a particular time-period in that it is a work of social meanings beyond individual impressions. However, the standards of criticism have changed, like the awareness system has changed as economy, culture or technology has evolved. The emergence of SNS has influenced the field of popular culture. It improves the role and participation of the public in criticism. Moreover, it breaks the previous paradigm of production and consumption in cultural industry. These changes bring not only the positive ones, such as improvement of diversity and freedom of criticism, but also the negative one, confusion of values due to the absence of criteria. This study mainly concerned debates and discourses of SNS on , a new song of IU, and focused on changes of aesthetic evaluations of culture performer, producer and audience. Especially, the authors tried to find out how such new technology has changed the criticism, and how it has influenced on our aesthetic consciousness.