• Bulletin of the Korean Chemical Society
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• v.16 no.11
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• pp.1093-1099
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• 1995

The polycondensations of bis(2-hydroxyethyl) naphthalate were kinetically investigated in the presence of various metallic compounds as catalysts at 295 ℃. The effect of the catalyst nature in the polycondensation has been studied. The order of catalytic activity on the formation of poly(ethylene 2,6-naphthalate) was found to be related to the stability constants which are indicated in an index of the catalytic activity.

• The Journal of Asian Finance, Economics and Business
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• v.8 no.2
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• pp.737-745
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• 2021

This study aims to determine whether there are differences in the average abnormal return, trading volume activity, and trading frequency activity in pharmaceutical stocks before and after the announcement of the first case of the coronavirus (COVID-19) in Indonesia. The sample was selected using a purposive sampling method and collected as many as nine pharmaceutical companies listed on the Indonesia Stock Exchange during 2019-2020. The data used in this study were secondary data in the form of daily data on stock closing prices, Composite Stock Price Index (IHSG), stock volume trading, number of shares outstanding, and stock trading frequency. This study was an event study with an observation period of 14 days, namely seven days before and seven days after the announcement of the coronavirus's first positive case in Indonesia. Hypothesis testing employed the paired sample t-test method. Based on the results, it was found that there was no difference in the average abnormal return of pharmaceutical stocks before and after the announcement of the first case of COVID-19. However, there was a difference in the average trading volume activity and the average trading frequency activity in pharmaceutical stocks before and after the announcement of the first case of COVID-19.

• The Journal of Korean Physical Therapy
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• v.32 no.6
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• pp.329-334
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• 2020

Purpose: The purpose of this study is to provide basic evidence on the need to approach osteoarthritis patients through a psychological factors-considering rehabilitation program by understanding how activity restrictions in osteoarthritis affect health-related quality of life and depression. Methods: This study assessed 3,761 osteoarthritis patients from the Korea National Health and Nutrition Examination Survey. The subjects were divided into two categories: with and without activity restriction. Results: The prevalence of osteoarthritis in women was higher than that of men (men: 19.7%; women: 80.3%), and high BMI increased the prevalence of osteoarthritis. The EQ-5D index of subjects with activity restriction was 0.84±0.18 (points), while in those without activity restriction was 0.93±0.12, and the diagnosis of depression was 15.8%, 8.2%. There was a statistically significant difference in the odds ratio for each item in the EQ-5D. Moreover, the odds ratio for depression with activity restriction was 2.098 compared with no activity restriction. Conclusion: Activity restriction of osteoarthritis patients significantly decreases the health-related quality of life and increase the probability of depression. Therefore, early diagnosis of depression symptoms to prevent deterioration of symptoms in patients with osteoarthritis and to increase compliance with rehabilitation treatment, and to provide arbitration, including treatment that can alleviate depression.

• Korean Journal of Animal Reproduction
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• v.19 no.2
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• pp.95-104
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• 1995

Mouse mammary epithelial cells(NMuMG) were maintained onto 6-well plates (3$\times$105 cells/well) or chambered slide (1$\times$104 cells/well), in DMEM supplemented with 10% fetal calf serum. After serum starvation for 24 hours, DMNB (1$\mu$M) was added and exposed to UV light (300nm, 3 second pulse) after 2 hours from DMNB addition in order to activate DMNB which induces a rapid transient increase in intracellular cAMP upon UV irradiation. EGF (100ng/ml) and/or IGF-I (10ng/ml) were treated at the time of UV irradiation. Nuclear labeling index was estimated as percent of nuclear labeled cells(percent of S phase of cells) by incorporation of 3H-thymidine into DNA(1 hour pulse with 1$\mu$Ci/ml). DMNB(1$\mu$M), EGF (100ng/ml) and/or IGF-I (10ng/ml) signifciantly increased nuclear labeling index than those of control (P<0.05). Addition of DMNB＋EGF or DMNB＋EGF＋IGF-I showed the interaction effect in nuclear labeling index (P<0.05). Protein kinase A activities by addition of EGF, IGF-I or EGF＋IGF-I were 10.5, 9.8 or 9.4 unit/mg protein, respectively, and no statistical difference was found in comparison with control (P>0.05). Additon of DMNB＋EGF showed the moderate interaction effect on tyrosyl kinase activity (P<0.1). In the fluorography analysis, there were no specific protein phosphorylation patterns were found at 1 or 15 minute by addition of DMNB. EGF and/or IGF-I. These results suggest that the interaction effect in nuclear labeling index by addition DMNB and EGF could be mediated through the modulation of tyrosyl kinase activity by cAMP.

• Korean Journal of Pharmacognosy
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• v.30 no.1
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• pp.40-47
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• 1999

To search for less toxic antiherpetic agents, the inhibitory effects of natural hesperetin on the plaque formation of herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in Vero cells were examined by the plaque reduction assay in vitro. Hesperetin inhibited plaque formations of HSV-1 and HSV-2 in a dose dependent manner. It also exhibited more potent antiherpetic activity on HSV-2 with selectivity index (SI) of 9.8 than on HSV-1 with SI of 8.4. The combined antiherpetic effects of hesperetin with nucleoside antiherpetic agents, acyclovir and vidarabine, were examined on the multiplication of these two strains of herpesviruses in Vero cells by the combination assay. The results of combination assay were evaluated by the combination index (CI) that was calculated by the multiple drug effect analysis. The combinations of hesperetin with acyclovir on HSV-1 and HSV-2 showed synergistic effects with CI values of $0.29{\sim}0.73$ for 50%, 70%, 90% effective levels and those with vidarabine showed partially synergistic or additive effects with CI values of $0.83{\sim}1.33$.

• Journal of the Korean Society of Food Science and Nutrition
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• v.39 no.2
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• pp.274-280
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• 2010

This study was to investigate the quality characteristics of noodles prepared with germinated brown rice and rice bran, and to determine the changes in GABA content and antioxidant activity of the noodles. These noodles were evaluated for cooking properties (cooking loss, swelling index, water holding capacity), total polyphenols, antioxidant activities (radical scavenging of ABTS and DPPH), and GABA contents. The addition of germinated rice bran in the range of 5, 10, and 15% showed a significant influence on cooking loss, although no effect on swelling index was observed. The raw and cooked noodles containing germinated brown rice and rice bran contained more GABA contents (2751.6~4176.7 and 5522.0~9617.8 nmol/20 g of fresh noodle, respectively) than those of non-germinated brown rice and rice bran. Noodles made with germinated brown rice and rice bran had similar total polyphenolics contents and antioxidant activities compared to noodles made with non-germinated brown rice and rice bran. Overall, the germinated brown rice could be used as a good ingredient to increase the nutritional value and antioxidant properties of wheat flour noodle without affecting the cooking properties.

• The Journal of the Korea Contents Association
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• v.13 no.11
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• pp.510-521
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• 2013

The awareness of education service is undergoing a transition from demand side to supply side. This study 1) develops an evaluation model of education service composed of three core factors(curriculum content, professor activities, job search activity) and additional factors(public welfare, education environment, campus life), 2) verifies a model using the structural equation model, 3) calculates the satisfaction measurement index of education service, and 4) proposes the results of IPA for evaluating the satisfaction measurement of education service. The results show significant notions that core factors(curriculum content, professor activities, job search activities) and additional factors(public welfare, education environment, campus life) determine students satisfaction, and that student satisfaction effects the recommend purpose significantly. Especially, student satisfaction influenced curriculum content, job search activity, campus life, public welfare, professor activities, education environment in order. This study provides improved strategic implications based on the calculated results of component satisfaction measurement index, and the results of IPA.

• Journal of the Ergonomics Society of Korea
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• v.25 no.4
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• pp.51-62
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• 2006

The concept of universal design has recently emerged as an important aspect of product design. Universal design is considerably analogous to ergonomic design in a way that it takes the capabilities and limitations of users into consideration during the product development process. However, relatively few studies have been devoted to reflect the practical use of ergonomic principles on universal design. This research attempts to develop a universal design index for mobile phone design to quantify how well a product complies with principles of universal design. The research also emphasizes on ergonomic principles as a basis of evaluation. A generation of the evaluation items was done by cross-checking among the personal, activity and product components. Personal components consist of human characteristics including age, physique, perceptual capacity, life-style, etc. Activity components were derived from those scenarios of mobile phone use while product components were composed of the parts to which a user interacts. Further analysis systematically generated a universal index from relationship matrices among the three components. The index was then used to test its suitability by applying to the evaluation of mobile phones currently on the market. This study demonstrates a development process through which evaluations can be made possible for universal design. The research suggests an improved approach to the appraisal of how well mobile phones are universally designed based on ergonomic principles.

• Safety and Health at Work
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• v.7 no.1
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• pp.43-48
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• 2016

Background: Work Ability Index (WAI) is a well-known and valid self-report tool that has been widely used in various studies to identify and avoid early retirement and work-related disability. Nevertheless, very few studies have been carried out to evaluate work ability in Iran. We aimed to investigate the WAI and the effect of work-related stress on it among Iranian workers. Methods: A cross-sectional, descriptive and analytic study was carried out among 449 workers from five working sectors in three big cities of Iran. Work ability and work-related stress were measured using the Persian version of WAI and the Persian version of Health and Safety Executive Stress Indicator Tool. Results: More than a third of the workers surveyed (34.70%) did not have an appropriate level of work ability (WAI < 37). There was a significant correlation between subscales of work-related stress and the mean score of WAI. Furthermore, the variables of body mass index, sleep quality, exercise activity, job tenure, and three subscales of work-related stress including demands, supervisor support, and role were significant predictors of WAI. Conclusion: According to the results of this study, the interventional programs must be focused on improving supervisors support, eliminating ambiguity and conflicts in the role of workers in their job and organization, reducing job demands, improving sleep quality, and increasing exercise activity.

• Journal of Forest and Environmental Science
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• v.34 no.6
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• pp.435-450
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• 2018

Phenological events of four Rhododendron tree species (viz. R. arboreum, R. arboreum ssp. delavayi var. delavayi, R. barbatum and R. kesangiae) was monitored in temperate mixed broad-leaved forests of Arunachal Pradesh, India. Phenological events like flower bud formation, flowering, fruit setting, fruit maturing, seed dispersal, leaf bud formation, leaf flushing, and leaf shedding were recorded. Indices i.e., phenophase sequence index (PSI), active phenophasic period of the species (APS) and index of reproductive/vegetative activity (RVA) were also calculated. Present study revealed that bark consistency, growth form and leaf pattern of the studied species have showed variations among the species. Rhododendron species exhibited the phenological events overlapping with other phenophases. The peak flower bud formation was observed during the winter; R. arboreum ssp. delavayi var. delavayi start flowering from December, while the flowering in rest three species exhibited during February to April. Fruit setting occurred during summer to autumn while fruit maturation revealed peak during November. Leaf bud formation illustrated two peaks in April and May, leaf flushing exhibited peak in June, while leaf shedding peaked during October to November. Active phenophasic period of the species were found 12 months, which revealed that species engage in various phenophase activities throughout the year. Phenophase sequence index ranged between 0.8 to 0.9 (PSI ${\geq}0.6$), signifies that species have a sequential arrangement of phenophases. Index of reproductive/vegetative activity of the species exemplified >1, indicate that the reproductive phenophases were dominance over vegetative phenophases. The study have provided substantial insight on the life cycle events of Rhododendron species and ecological approaches for further scientific study with recent climate change and effective management and conservation.