• 제목/요약/키워드: activity coefficient model

검색결과 164건 처리시간 0.023초

학령기 아동을 위한 활동 참여 평가도구(Activity Participation Assessment)의 타당도 연구 (The Validity of Activity Participation Assessment for School-Age Children)

  • 김세연
    • 대한감각통합치료학회지
    • /
    • 제17권1호
    • /
    • pp.19-29
    • /
    • 2019
  • 목적 : 본 연구의 목적은 학령기 아동을 위한 활동 참여 평가도구(Activity Participation Assessment; APA)의 타당도를 알아보는 것이다. 연구방법 : 초등학생 207명을 대상으로 APA 30문항, PACS(Pediatric Activity Card Sort) 75문항, CAPE(Children's Assessment of Participation and Enjoyment) 55문항으로 구성된 설문지를 실시하였다. APA의 구인타당도를 알아보기 위해 확인적 요인분석을 실시하였으며, 수렴타당도와 판별타당도는 평균분산추출과 상관계수 제곱값을 통해 검증하였으며, 공인타당도는 APA와 PACS 및 CAPE의 피어슨의 상관계수를 통해 검증하였다. 연구결과 : 구인타당도는 확인적 요인분석 결과 수정된 위계적 2차 모형이 적합한 수준으로 나타났으며(p<.001), 수렴타당도는 모든 하위요인에서 평균분산 추출값이 .50이상으로 나타나 입증되었으며, 판별타당도는 평균분산 추출값이 결정계수인 0.239보다 더 크게 나타나 입증되었다. 공인타당도 분석에서 APA 항목 전체와 PACS의 자기관리는 .494(p<.01), 학교/생산성 .575(p<.01), 취미/사회 활동 .647(p<.01), 스포츠 .303(p<.01)으로 모두 정적 상관이 있는 것으로 나타났다. 또한 APA 항목 전체와 CAPE의 여가활동은 .490(p<.01), 신체적 활동 .329(p<.01), 사회 활동 .571(p<.01), 기술에 기초한 활동 .401(p<.01), 자기계발 활동 .390(p<.01)으로 모두 정적 상관관계를 보였다. 결론 : APA는 구인타당도, 수렴타당도, 변별타당도와 공인타당도가 입증되어 국내 학령기 아동의 활동 참여를 측정하는 검사로써 타당한 도구로 사용될 수 있다.

Urokinase Inhibitor Design Based on Pharmacophore Model Derived from Diverse Classes of Inhibitors

  • Shui, Liu;Bharatham, Nagakumar;Bharatham, Kavitha;Lee, Keun-Woo
    • Bioinformatics and Biosystems
    • /
    • 제1권2호
    • /
    • pp.115-122
    • /
    • 2006
  • A three-dimensional pharmacophore model was developed based on 24 currently available inhibitors, which were rationally selected from 472 compounds with diverse molecular structure and bioactivity, for generating pharmacophore of uPA (Urokinase Plasminogen Activator) inhibitors. The best hypothesis (Hypo1) comprised of five features, namely, one positive ionizable group, one hydrogen-bond acceptor group and three hydrophobic aromatic groups. The correlation coefficient, root mean square deviation and cost difference were 0.973, 0.695, and 94.291 respectively, suggesting that a highly predictive pharmacophore model was successfully obtained. The application of the model showed great success in predicting the activities of 251 known uPA inhibitors (test set) with a correlation coefficient of 0.837, and there was also none of the outcome hypotheses that had similar cost difference and RMS deviation (RMSD) with that of the initial hypothesis generated by Cat-Scramble validation test with 95% confidence level. Accordingly, our model should be reliable in identifying structurally diverse compounds with desired biological activity.

  • PDF

THERMOSPHERIC NEUTRAL WINDS WITHIN THE POLAR CAP IN RELATION TO SOLAR ACTIVITY

  • Won, Young-In;Killeen, T.L.;Niciejewski, R.J.
    • International Union of Geodesy and Geophysics Korean Journal of Geophysical Research
    • /
    • 제23권1호
    • /
    • pp.1-11
    • /
    • 1995
  • Thermospheric neutral winds and temperatures have been collected from the ground-based Fabry-Perot interferometer (FPI) at Thule Air Base ($76.5^{\circ}N{\;}69.0^{\circ}W$), Greenland since 1985. The thermospheric observations are obtained by determining the Doppler characteristics f the [OI] 6300 ${\AA}$ emissions of atomic oxygen. The FPI operates routinely during the winter season, with a limitation in the observation by the existence of clouds. For this study, data acquired from 1985 to 1991 were analyzed. The neutral wind measurements from these long-term measurements are used to investigate the influence of solar cycle variation on the high-latitude thermospheric dynamics. These data provide experimental results of the geomagnetic polar cap are also compared with the predictions of two semiempirical models : the vector spherical harmonics (VSH) model of Killeen et al. (1987) and the horizontal wind model (HWM) of Hedin et al. (1991). The experimental results show a good positive correlation between solar activity and thermospheric wind speed over the geomagnetic polar cap. The calculated correlation coefficient indicates that an increase of 100 in F10.7 index corresponds to an increase in wind speed of about 100 m/s. The model predictions reveal similar trends of wind speed variation as a function of solar activity, with the VSH and HWM models tending to overestimate and underestimate the wind speed, respectively.

  • PDF

Accuracy Analysis of Predicted CODE GIM in the Korean Peninsula

  • Ei-Ju Sim;Kwan-Dong Park;Jae-Young Park;Bong-Gyu Park
    • Journal of Positioning, Navigation, and Timing
    • /
    • 제12권4호
    • /
    • pp.423-430
    • /
    • 2023
  • One recent notable method for real-time elimination of ionospheric errors in geodetic applications is the Predicted Global Ionosphere Map (PGIM). This study analyzes the level of accuracy achievable when applying the PGIM provided by the Center for Orbit Determination of Europe (CODE) to the Korean Peninsula region. First, an examination of the types and lead times of PGIMs provided by the International GNSS Service (IGS) Analysis Center revealed that CODE's two-day prediction model, C2PG, is available approximately eight hours before midnight. This suggests higher real-time usability compared to the one-day prediction model, C1PG. When evaluating the accuracy of PGIM by assuming the final output of the Global Ionosphere Map (GIM) as a reference, it was found that on days with low solar activity, the error is within ~2 TECU, and on days with high solar activity, the error reaches ~3 TECU. A comparison of the errors introduced when using PGIM and three solar activity indices-Kp index, F10.7, and sunspot number-revealed that F10.7 exhibits a relatively high correlation coefficient compared to Kp-index and sunspot number, confirming the effectiveness of the prediction model.

Relationship of Phenolic Compounds and Free-radical Scavenging Activity in Black and Red Rice Extract

  • Hu, Gao-Sheng;Xu, Kai-Xiu;Jeong, Soon Jae;Kim, Doh-Hoon
    • 한국육종학회지
    • /
    • 제42권2호
    • /
    • pp.129-138
    • /
    • 2010
  • Total phenolic content, total anthocyanin content and antioxidant activity were analyzed from rice samples collected in Korea, Japan and China. The results showed that the total phenolic content and free-radical scavenging activity differed significantly in these rice lines. The correlation between content and activity was subsequently investigated. The results showed that in black rice, anthocyanin was the major phenolic component and that both phenolic content and anthocyanin content were closely correlated with free-radical scavenging activity. Reverse Phase High Performance Liquid Chromatography (RP-HPLC) data showed that cyanidin-3-O-glucoside and peonidin-3-O-glucoside composed about 90% of the total anthocyanin content in black rice and in red rice. In the red rice extract, the total phenolic content produced a high correlation coefficient with antioxidant activity but correlated very poorly with the total anthocyanin content. The $OD_{458}$ and the $OD_{500}$ values which represent the proanthocyanidin content of the rice extract, produced high correlation coefficients with antioxidant activity and total phenolic content. These results suggest that the $OD_{458}$ and the $OD_{500}$ values can be used to evaluate the quality of red rice. In addition, based on the data obtained, a competitive accumulation model of anthocyanin and proanthocyanidin in black and red rice was proposed.

여성의 개인적 특성과 생활양식요인을 이용한 골량감소 예측모형 (Prediction Model for Reduced Bone mass in Women using Individual Characteristics & Life Style Factors)

  • 이은남;이은옥
    • 근관절건강학회지
    • /
    • 제5권1호
    • /
    • pp.83-109
    • /
    • 1998
  • This study was carried out to identify the Important modifiable risk factors for reduced bone mass and to construct prediction model which can classify women with either low or high bone mass. Through the literature review, individual characteristics such as age, body weight, height, education level, family history, age of menarche, postmenopausal period, gravity, parity, menopausal status, and breast feeding period were identified and factors of life style such as past milk consumption, past physical activity, present daily activity, present calcium intake, alcohol intake, cigarette smoking, coffee consumption were identified as influencing factors of reduced bone mass in women. Four hundred and eighty women aged between 28 and 76 who had given measurement bone mineral density by dual energy x-ray absortiometry in lumbar vertebrae and femur from July to October, 1997 at 4 general hospitals in Seoul and Pusan were selected for this study. Women were excluded if they had a history of any chronic illness such as rheumatoid arthritis, diabetes mellitus, hyperthroidism, & gastrointestinal disorder and any medication such as calcium supplements, calcitonin, estrogen, thyroxine, antacids, & corticosteroids known affect bone. As a result of these exclusion criteria, four hundred and seventeen women were used for analysis. Multiple logistic regression model was developed for estimating the likelihood of the presence or absence of reduced bone mass. A SAS procedure was used to estimate risk factor coefficient. The results are as follows For lumbar spine, the variables significant were age, body weight, menopause status, daily activity, past milk consumption, and past physical activity(p<0.01), while for femoral Ward's triangle, age, body weight, level of education, past milk consumption, past physical activity(p<0.001). Past physical activity, present daily activity and past milk consumption are the most powerful modifiable predictors in vertebrae and femur among the predictors. When the model performance was evaluated by comparing the observed outcome with predicted outcome, the model correctly identified 74.1% of persons with reduced bone mass and 84.5% of persons with normal bone mass in the lumbar vertebrae and 82.9% of persons with reduced bone mass and 75.0% of persons with normal bone mass in the femoral Ward's triangle. On the basis of these results, a number of recommendations for the management of reduced bone mass may be made : First, those woman who are classified as high risk group of the reduced bone mass in the prediction model should examine the bone mineral density to further examine the usefulness of this model. Second, the optimal amount of milk consumption and a regular weight bearing exercise in childhood, adolescence, and early adult should be ensured.

  • PDF

Orbit determination for the KOMPSAT-1 Spacecraft during the period of the solar maximum

  • Kim, Hae-Dong;Kim, Eun-Kyou;Choi, Hae-Jin
    • International Journal of Aeronautical and Space Sciences
    • /
    • 제6권1호
    • /
    • pp.71-76
    • /
    • 2005
  • The KOMPSAT-1 satellite, launched into a circular sun synchronous orbit on Dec. 21, 1999, entered its$6^{th}$year of successful operation this year. The purposes of the mission are to collect earth images (6.6 m resolution), multi-spectral images of the ocean, and to collect information on the particle environment of the low earth orbit. For normal operation, KOMPSAT-1 orbits are determined using GPS navigation solutions. However, at the start of the life of KOMPSAT-1, the 11-year solar activity cycle was at a maximum. Solar flux was maintained at this level until 2002, and thereafter reduced to a moderate level by 2004. Thus, the OD (Orbit Determination) accuracy has varied according to the solar activity. This paper presents the degree to which the OD accuracy could be degraded during a high solar activity period compared with that of a (relatively) low solar activity period. We investigated the effect of the use of solve-for parameters such as a drag coefficient ($C_D$), solar radiation coefficient ($C_R$), and the general accelerations ($G_A$) on OD accuracy with solar activity. For the evaluation of orbit determination accuracy, orbit overlap comparison is used since no independent orbits of comparable accuracy are available for comparison. The effect of the use of a box-wing model instead of a constant cross-sectional area is also investigated.

섬유조직염환자의 수면장애에 영향을 미치는 요인 (Affecting Factor on Sleep Disorder in Patients with Fibromyalgia)

  • 한상숙
    • 근관절건강학회지
    • /
    • 제11권2호
    • /
    • pp.176-186
    • /
    • 2004
  • Purpose: The purpose this research was to provide with basic data in the control of the sleep disorder found in the patients with fibromyalgia by analysing the main factors that affect that. Method: At two university medical center, appointed 171 out-patients diagnosed of fibromyalgia according to the conditions by American College of Rheumatology(1990). The research instruments used in this study were VAS Scale(Anxiety, fatigue, pain, joint stiffness and depression), physical activity family support, the number of tender points and Self-efficacy scale. In data analysis, SPSS 11.0 program was utilized and data were analyzed using descriptive statistics, Pearson's correlation coefficient and multiple regression. Result: The main factors that affect the sleep disorder of patients with fibromyalgia were fatigue, physical activity, and depressions which explained 46.2% of the sleep disorder. Conclusion: It has been confirmed that the regression equation model of this research may serve as a sleep disorder prediction factors in patients with fibromyalgia.

  • PDF

Dimethyl Sulfoxide와 Ethylene Glycol을 이용하여 에탄올 수용액으로부터 고순도 에탄올을 생산하기 위한 추출증류공정 (Extractive Distillation Process for the Production of Highly Purified Ethanol from Aqueous Solution using Dimethyl Sulfoxide and Ethylene Glycol)

  • 노상균
    • 청정기술
    • /
    • 제22권4호
    • /
    • pp.241-249
    • /
    • 2016
  • 본 연구에서는 디메틸설폭사이드(dimethyl sulfoxide, DMSO)와 에틸렌글리콜(ethylene glycol, EG)을 이용하여 에탄올 수용액으로부터 99.7 wt% 이상의 고순도 에탄올을 생산하기 위한 추출증류공정에 대해서 2기의 증류탑 배열과 3기의 증류탑 배열 사이의 공정을 비교하였다. 두 가지 용매를 사용한 3기의 증류탑 배열에 대해서는 총 재비기의 heat duty의 합이 최소가 되는 농축기 상부에서의 에탄올의 조성을 최적화 작업을 통해서 결정하였다. 열역학 모델식으로는 NRTL 액체활동도계수 모델식을 사용하였으며 Schneider electric 사의 PRO/II with PROVISION 9.4를 사용하였다. 용매의 성능은 EG보다는 DMSO가 더 좋은 것으로 나타났으며, 전체적인 유틸리티 소모량에 있어서는 농축기 하부에서 원료 중에 포함되어 있는 액상의 물의 일부를 액상으로 제거하기 때문에 3기의 증류탑 배열이 2기의 증류탑 배열보다 더 우수한 것을 알 수 있었다.

CalTOX 모델을 이용한 대산 석유화학단지의 활동단계에 따른 벤젠 흡입 노출평가 (Prediction of Inhalation Exposure to Benzene by Activity Stage Using a Caltox Model at the Daesan Petrochemical Complex in South Korea)

  • 이진헌;이민우;박창용;박상현;송영호;김옥;신지훈
    • 한국환경보건학회지
    • /
    • 제48권3호
    • /
    • pp.151-158
    • /
    • 2022
  • Background: Chemical emissions in the environment have rapidly increased with the accelerated industrialization taking place in recent decades. Residents of industrial complexes are concerned about the health risks posed by chemical exposure. Objectives: This study was performed to suggest modeling methods that take into account multimedia and multi-pathways in human exposure and risk assessment. Methods: The concentration of benzene emitted at industrial complexes in Daesan, South Korea and the exposure of local residents was estimated using the Caltox model. The amount of human exposure based on inhalation rate was stochastically predicted for various activity stages such as resting, normal walking, and fast walking. Results: The coefficient of determination (R2) for the CalTOX model efficiency was 0.9676 and the root-mean-square error (RMSE) was 0.0035, indicating good agreement between predictions and measurements. However, the efficiency index (EI) appeared to be a negative value at -1094.4997. This can be explained as the atmospheric concentration being calculated only from the emissions from industrial facilities in the study area. In the human exposure assessment, the higher the inhalation rate percentile value, the higher the inhalation rate and lifetime average daily dose (LADD) at each activity step. Conclusions: Prediction using the Caltox model might be appropriate for comparing with actual measurements. The LADD of females was higher ratio with an increase in inhalation rate than those of males. This finding would imply that females may be more susceptible to benzene as their inhalation rate increases.