• Convergence Security Journal
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• v.8 no.4
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• pp.51-56
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• 2008

A combination of VPNs and dial-up access, such as DSL and Cable, usually provides the cost-effective solution as the substitution of private networks on high-cost leased line. The business demand for high availability has increased with VPN spreading. This paper presents the schemes for a high availability of network access and a load balancing of network traffic in VPN gateways by using multiple links or multihoming capability based on active-active approach. The high availability and load balancing of network links can be achieved by duplicating external network access into multiple independent links. This can provide a continuous network connection to internal users even if one of the links is failed. Moreover, it can provide twice network bandwidth by distributing the traffic into the links. Static and dynamic algorithms are proposed as the load balancing algorithms.

• Herbal Formula Science
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• v.26 no.3
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• pp.237-250
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• 2018

Objectives : This study is a pharmacological network approach, aimed to identify the potential active compounds contained in Curcumae Radix, and their associated targets, to predict the various bio-reactions involved, and finally to establish the cornerstone for the deep-depth study of the representative mechanisms. Methods : The active compounds of Curcumae Radix have been identified using Traditional Chinese Medicine System Pharmacology Database and Analysis Platform. The UniProt database was used to collect each of information of all target proteins associated with the active compounds. To find the bio-metabolic processes associated with each target, the DAVID6.8 Gene Functional classifier tool was used. Compound-Target and Target-Pathway networks were analyzed via Cytoscape 3.40. Results : The target information from 32 potential active compounds of Curcumae Radix was collected through TCMSP analysis. The active compounds interact with 133 target genes engaging in total of 885 biological pathways. The most relevant pathway was the lipid-related metabolism, in which 3 representative active compounds were naringenin, oleic acid, and ${\beta}-sitosterol$. The mostly targeted proteins in the lipid pathway were ApoB, AKT1 and PPAR. Conclusions : The pharmacological network analysis is convenient approach to predict the overall metabolic mechanisms in medicinal herb research, which can reduce the processes of various experimental trial and error and provide key clues that can be used to validate and experimentally verify the core compounds.

• Korean Journal of Exercise Nutrition
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• v.25 no.3
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• pp.28-35
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• 2021

[Purpose] As Panax ginseng C. A. Meyer (ginseng) exhibits various physiological activities and is associated with exercise, we investigated the potential active components of ginseng and related target genes through network pharmacological analysis. Additionally, we analyzed the association between ginseng-related genes, such as the G-protein-coupled receptors (GPCRs), and improved exercise capacity. [Methods] Active compounds in ginseng and the related target genes were searched in the Traditional Chinese Medicine Database and Analysis Platform (TCMSP). Gene ontology functional analysis was performed to identify biological processes related to the collected genes, and a compound-target network was visualized using Cytoscape 3.7.2. [Results] A total of 21 ginseng active compounds were detected, and 110 targets regulated by 17 active substances were identified. We found that the active compound protein was involved in the biological process of adrenergic receptor activity in 80%, G-protein-coupled neurotransmitter in 10%, and leucocyte adhesion to arteries in 10%. Additionally, the biological response centered on adrenergic receptor activity showed a close relationship with G protein through the beta-1 adrenergic receptor gene reactivity. [Conclusion] According to bioavailability analysis, ginseng comprises 21 active compounds. Furthermore, we investigated the ginseng-stimulated gene activation using ontology analysis. GPCR, a gene upregulated by ginseng, is positively correlated to exercise. Therefore, if a study on this factor is conducted, it will provide useful basic data for improving exercise performance and health.

• Journal of KIISE:Information Networking
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• v.31 no.4
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• pp.384-392
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• 2004

Mobile contents service providers have some difficulties to timely and proper service deployment due to rapid development cycle of diverse portable devices with different capabilities. A way to resolve the problem is to introduce a mobile contents service paltform that can adapt original mobile contents to diverse devices dynamically and automatically. In this paper, we propose a mobile contents service platform based on active network mechanisms, called Mobile Content Adaptation Network(MobiCAN). The MobiCAN node provides effective service deployment, execution, and maintenance features and accommodates service layering and service customization capabilities for easy deployment. The basic functional units of the MobiCAN node are micro services with well-defined service interfaces and service layering features. For reliable services among the MobiCAN nodes, we design new distributed and robust Overlay Management Protocols(OMPs). As an example of practical MobiCAN applications, we finally describe Dynamic Contents Customization Proxy(DCCP) service.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.36 no.1
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• pp.50-63
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• 2023

Objectives : This study used a network pharmacology approach to explore the active compounds and therapeutic mechanisms of Yijin-tang on Meniere's disease. Methods : The active compounds of Yijin-tang were screened via the TCMSP database and their target proteins were screened via the STITCH database. The GeneCard was used to establish the Meniere's disease-related genes. The intersection targets were obtained through Venny 2.1.0. The related protein interaction network was constructed with the STRING database, and topology analysis was performed through CytoNCA. GO biological function analysis and KEGG enrichment analysis for core targets were performed through the ClueGO. Results : Network analysis identified 126 compounds in five herbal medicines of Yijin-tang. Among them, 15 compounds(naringenin, beta-sitosterol, stigmasterol, baicalein, baicalin, calycosin, dihydrocapsaicin, formononetin, glabridin, isorhamnetin, kaempferol, mairin, quercetin, sitosterol, nobiletin) were the key chemicals. The target proteins were 119, and 7 proteins(TNF, CASP9, PARP1, CCL2, CFTR, NOS2, NOS1) were linked to Meniere's disease-related genes. Core genes in this network were TNF, CASP9, and NOS2. GO/KEGG pathway analysis results indicate that these targets are primarily involved in regulating biological processes, such as excitotoxicity, oxidative stress, and apoptosis. Conclusion : Pharmacological network analysis can help to explain the applicability of Yijin-tang on Meniere's disease.

• Proceedings of the Korea Information Processing Society Conference
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• 2003.05b
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• pp.1161-1164
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• 2003

본 논문은 ALAN(Application Level Active Network)상에서 GME(Generic Modeling Environment)라고 불리는 컴포지션 메커니즘을 이용하는 AWCS(Adaptive Web Caching Service)에 관하여 언급하였다. ALAN상의 웹 캐싱의 요구사항은 자치 구성성(self-configuration)과 자치 적응성(self-adaptation)이다 이러한 요구사항을 지원하기 위해서 본 논문에서는 친AN상에서 IN(Intelligent Inetwork)에서 유래된 SCE(Service Creation Environment)와 유사한 서비스 컴포지션 메커니즘인 GME를 이용하여 AWCS 의 설계 및 구현에 관하여 언급하였다

• Journal of the Korean Institute of Telematics and Electronics
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• v.14 no.4
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• pp.32-37
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• 1977

A generalized product graph of the network containing active and/or coupled elements has been presented. This graph is obtained directly from the current graph and voltage graph and can be used to determine the Mason's determinant. An example is presented and discussed.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2005.06a
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• pp.519-522
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• 2005

Decentralized Dynamic Surface Control(DDSC) for a class of nonlinear system interconnected via sensor network is presented in this paper. While a centralized design approach of DSC was developed in [1], the decentralized approach to deal with complex large-scale systems is proposed under the assumption that interconnected functions among subsystems are known via sensor network. As shown in [2], the separation principle for DDSC will allow us to design an estimation filter independently. Furthermore, the theoretical results are used to design and simulate an active vibration isolator under the assumption that many embedded sensors are distributed and communicate each other via wireless communication.

• International Journal of Contents
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• v.11 no.1
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• pp.52-61
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• 2015

In the past decade, East Asian Research has received attention from researchers as well as in South Korea society-at-large. The broad category of East Asian Research includes various disciplinary fields, such as "history, economics, and politics; however, few studies have used quantitative analysis to explore its development. In this paper, we used network analysis to identify the disciplines and active research areas, focusing on productivity, collaboration patterns, and citation networks of East Asian Research in South Korea. For this study, 6,646 journal publications related with East Asian Research and indexed by KCI (Korean Citation Index) during the 10-year period of 2004-2013 were considered. Results show that East Asian Research was led during this period by sole-researchers, rather than interdisciplinary studies. Moreover, a co-institution network represents active institutions with a high degree and collaborative centrality. In terms of journal-journal citation networks, journals belonging to both "history" and "Korean literature" disciplines were dominant.

• Information and Communications Magazine
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• v.19 no.8
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• pp.128-136
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• 2002

It is an active security that has the research field which has more powerful responding mechanism comparing to current network security technology, has an ability to introduce new security mechanism according to changing our environments, and can support effective security management. Our goal is to introduce a new category of internet security technologies on network survivability: active security technology. It is a new security technology that blocking network or computers. before malicious traffics are reached to them, including protecting hosts or small area network from hackers.