• The Journal of the Acoustical Society of Korea
• /
• 제24권2E호
• /
• pp.46-53
• /
• 2005

Agency for Defense Development (ADD) developed the Submarine Acoustic Information Management System (SAIMS Version 1.0) capable of interfacing some submarine sensors in operation and predicting detection environments for sonars. The major design concepts are as follows: 1) A proper acoustic model is examined and optimized to cover wide spectra of frequency ranges for both active and passive sonars. 2) Interfacing the submarine sensors to an electric navigation chart, the system attempts to maximize the applicability of the information produced. 3) The state-of-the-art database in large area is built and managed on the system. 4) An algorithm, which is able to estimate a full sound speed profile from the limited oceanographic data, is developed and employed on the system. This paper briefly describes design concepts and algorithms embedded in the SAIMS. The applicability of the SAIMS was verified through three sea experiments in October 2003-February 2004.

• Journal of Advanced Marine Engineering and Technology
• /
• 제38권5호
• /
• pp.581-588
• /
• 2014

Extensive researches toward pool boiling characteristics have been widely investigated. However, the correct understanding of its boiling crisis by Critical Heat Flux (CHF) phenomenon during steady and transient heat transfer as a fundamental database for designing heat generation systems is still need to be clarified. The pool boiling CHFs were investigated to clarify the generalized phenomena of transition to film boiling at transient condition. The CHFs were measured on 1.0 mm diameter horizontal cylinder of platinum for exponential heat generation rates with various periods for saturated liquids at atmospheric pressure. The incipience of boiling processes was completely different depending on pre-pressurization. Also, the dependence of pre-pressure in transient CHFs changed due to the wettability of boiling liquids. The trend of typical CHFs were clearly divided into the first, second and third groups for long, short and intermediate periods, respectively. By the effect of pre-pressurization, the boiling incipience mechanism was replaced from that by active cavities entraining vapor to that by the HSN in originally flooded cavies.

• Journal of Microbiology
• /
• 제44권4호
• /
• pp.432-438
• /
• 2006

Twelve actinomycete strains were isolated from Egyptian soil. The isolated actinomycete strains were then screened with regard to their potential to generate antibiotics. The most potent of the producer strains was selected and identified. The cultural and physiological characteristics of the strain identified. the strain as a member of the genus Streptomyces. The nucleotide sequence of the 16S rRNA gene (1.5kb) of the most potent strain evidenced a 99% similarity with Streptomyces spp. and S. aureofaciens 16S rRNA genes, and the isolated strain was ultimately identified as Streptomyces sp. MAR01. The extraction of the fermentation broth of this strain resulted in the isolation of one major compound, which was active in vitro against gram-positive, gram-negative representatives and Candida albicans. The chemical structure of this bioactive compound was elucidated based on the spectroscopic data obtained from the application of MS, IR, UV, $^1H$ NMR, $^{13}C$ NMR, and elemental analysis techniques. Via comparison to the reference data in the relevant literature and in the database search, this antibiotic, which had a molecular formula of $C_{19}H_{29}NO_2$ and a molecular weight of 303.44, was determined to differ from those produced by this genus as well as the available known antibiotics. Therefore, this antibiotic was designated Meroparamycin.

• 중소기업융합학회논문지
• /
• 제5권4호
• /
• pp.37-42
• /
• 2015

ICT의 발달로 인해 다양한 공격들이 발달되고 있고, 활발해 지고 있다. 최근에 악성코드를 이용한 APT공격들이 빈번하게 발생하고 있다. 지능형 지속 위협은 해커가 다양한 보안 위협을 만들어 특정 기업이나 조직의 네트워크에 지속적으로 공격하는 것을 의미한다. 악성코드나 취약점을 이용하여 기업이나 기관의 조직 내부 직원의 PC를 장악한 후 그 PC를 통해 내부에서 서버나 데이터베이스에 접근한 뒤 기밀정보 등을 빼오거나 파괴한다. 본 논문에서는 APT 공격과정을 통하여 APT 공격에 어떻게 대응할 수 있는 지 방안을 제시하였다. 악성코드 공격자의 공격소요 시간을 지연시키는 방안을 모색하고, APT 공격에 대한 탐지 및 제거 할 수 있는 방안을 제시하였다.

• 한국컴퓨터정보학회논문지
• /
• 제11권2호
• /
• pp.153-158
• /
• 2006

인터넷을 통한 문제풀이와 학습의 효과는 나날이 늘어가고 있는 추세이다. 본 논문에서는 자격증에 대한 정보와 필기 및 실기평가 문제가 데이터베이스화되어 있어 쉽게 접근할 수 있는 능동적인 학습 방법을 제시한다. 먼저, 가중치에 의한 사용자 프로파일의 정보를 이용하여 사용자의 특성에 맞는 문제를 필터링하여 제공함으로써 개별 평가가 가능하고 학습의 동기를 증진시키고 성취감을 느끼게 해준다. 그리고 자격증취득에 대한 지도와 관리를 통해 자격증 취득률을 향상시키고 진로에 대한 적극적인 관심과 인식을 새롭게 할 것이다. 본 논문의 방법을 이용한 경우 자격증 취득 시험 성적이 10점정도 상승한 것으로 나타났다.

• Journal of Nuclear Fuel Cycle and Waste Technology
• /
• 제1권1호
• /
• pp.9-27
• /
• 2013

Nagra was established in 1972 by the Swiss nuclear power plant operators and the Federal Government to implement permanent and safe disposal of all types of radioactive waste generated in Switzerland. The Swiss Nuclear Energy Act specifies that these shall be disposed of in deep geological repositories. A number of different geological formations and sites have been investigated to date and an extended database of geological characteristics as well as data and state-of-the-art methodologies required for the evaluation of the long-term safety of repository systems have been developed. The research, development, and demonstration activities are further supported by the two underground research facilities operating in Switzerland, the Grimsel Test Site and the Mont Terri Project, along with very active collaboration of Nagra with national and international partners. A new site selection process was approved by the Federal Government in 2008 and is ongoing. This process is driven by the long-term safety and feasibility of the geological repositories and is based on a step-wise decision-making approach with a strong participatory component from the affected communities and regions. In this paper a brief history and the current status of the Swiss radioactive waste management program are presented and special characteristics that may be useful beyond the Swiss program are highlighted and discussed.

• Bulletin of the Korean Chemical Society
• /
• 제31권12호
• /
• pp.3644-3652
• /
• 2010

The metallo-$\beta$-lactamases ($M{\beta}Ls$) are clinically significant enzymes which readily hydrolyze most $\beta$-lactam antibiotics. Discovering potential inhibitors for the $M{\beta}Ls$ is an expensive, time consuming endeavor. Virtual screening can sieve out inhibitor candidates with incompatible features prior to synthesis, decreasing these costs. Using Autodock 4.0, the binding locations and energies of four previously-studied potential inhibitors and four additional compounds obtained from the National Cancer Institute (NCI) database were computationally calculated. Based on the docking models of these eight compounds, we then designed several hypothetical inhibitor structures, compounds A through F, and performed their respective docking experiments. The docking results for compound F showed that it binds to the zinc containing active sites with a lowest predicted binding energy of -6.70 kcal/mol, suggesting F is the most likely potential $M{\beta}L$ inhibitor.

• Journal of Preventive Medicine and Public Health
• /
• 제40권4호
• /
• pp.278-284
• /
• 2007

Despite extensive researches and pre-market clinical trials, only limited information on the adverse drug reactions (ADRs) of a drug can be collected at the time of market approval from regulatory agency. ADRs constitute a major public health problem. Post-marketing surveillance of drugs is important to detect signals for ADR. In Korea, one of the main methods for monitoring the safety of marketed drugs is spontaneous reporting system of suspected ADRs. Re-examination and re-evaluation system are in force for monitoring safety of new market approval drugs and currently under marketing drugs, respectively. Recently, regional pharmacovigilance centers were designated from Korean Food and Drug Administration for facilitating ADR surveillance. Over recent years, with the development of information technology, there has been an increased interest in establishing data mining system for detecting signals from Health Insurance Review Agency database. The purpose of this paper is to review the current status of Korean ADR surveillance system and suggest the possible solutions for developing active pharmacovigilance system in Korea.

• 한국주거학회논문집
• /
• 제14권4호
• /
• pp.77-85
• /
• 2003

The facade design of apartment is getting more important, since residents'needs on raising the quality of housing have increased, and also public interests on urban landscape are higher than before. As a way of improving facade design the necessity of remodeling consequently has been risen. The government also relieves the regulations related to remodeling. A apartment facade design should address how to express both identities and aesthetic tastes of residents, so they want to reflect their own ideas and opinions on the apartment facade design during the remodeling process. It is not always easy, unfortunately, to reflect residents'ideas and opinions due to the public characteristics of apartment facades and absence of tools that support effective design participation. This paper proposes an internet-based collaborative design process that supports residents'active participation in the exterior remodeling process of apartment. We outline three main issues involved in developing the design system: 1) a semantic facade database built upon classification of building facades; 2) an Internet-based facade modeler based on a real-time, rule-based procedural modeling method; and finally 3) the virtual reality(VR) simulation that allows a group of designers and residents to design in a collaborative fashion.

• Journal of Information Science Theory and Practice
• /
• 제4권2호
• /
• pp.53-65
• /
• 2016

The authors in this paper aim to identify the growth of literature on Intellectual Property Rights (IPRs). The research publications on IPRs were downloaded from the Scopus online citation database and the authors found that there were 1,513,138 records contributed globally over a period of 10 years from 2005 to 2014. The distribution of publications based on the year, country, and document type were studied. Relative growth rate (RGR) of the publications and doubling time (T_d) were calculated. Most productive organizations, source titles, and the productive authors on IPR research were studied. Most cited articles in the study area were identified. The results show that a number of publications under the subjects Medicine and Engineering were produced. The developed countries are very active in IPR research and producing publications. It is found that one institution which holds the sixth place among the top 10 most productive institutions belongs to Brazil, a developing country. Two developing countries such as China and India hold second and tenth positions respectively in the top 10 countries contributing literature on IPRs.