• Title/Summary/Keyword: active components

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Therapeutic Potential of Active Components from Acorus gramineus and Acorus tatarinowii in Neurological Disorders and Their Application in Korean Medicine

  • Cheol Ju Kim;Tae Young Kwak;Min Hyeok Bae;Hwa Kyoung Shin;Byung Tae Choi
    • Journal of Pharmacopuncture
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    • v.25 no.4
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    • pp.326-343
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    • 2022
  • Neurological disorders represent a substantial healthcare burden worldwide due to population aging. Acorus gramineus Solander (AG) and Acorus tatarinowii Schott (AT), whose major component is asarone, have been shown to be effective in neurological disorders. This review summarized current information from preclinical and clinical studies regarding the effects of extracts and active components of AG and AT (e.g., α-asarone and β-asarone) on neurological disorders and biomedical targets, as well as the mechanisms involved. Databases, including PubMed, Embase, and RISS, were searched using the following keywords: asarone, AG, AT, and neurological disorders, including Alzheimer's disease, Parkinson's disease, depression and anxiety, epilepsy, and stroke. Meta-analyses and reviews were excluded. A total of 873 studies were collected. A total of 89 studies were selected after eliminating studies that did not meet the inclusion criteria. Research on neurological disorders widely reported that extracts or active components of AG and AT showed therapeutic efficacy in treating neurological disorders. These components also possessed a wide array of neuroprotective effects, including reduction of pathogenic protein aggregates, antiapoptotic activity, modulation of autophagy, anti-inflammatory and antioxidant activities, regulation of neurotransmitters, activation of neurogenesis, and stimulation of neurotrophic factors. Most of the included studies were preclinical studies that used in vitro and in vivo models, and only a few clinical studies have been performed. Therefore, this review summarizes the current knowledge on AG and AT therapeutic effects as a basis for further clinical studies, and clinical trials are required before these findings can be applied to human neurological disorders.

Design of active intelligent decision support system for investment evaluation

  • 조현석;서의호
    • Proceedings of the Korean Operations and Management Science Society Conference
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    • 1996.10a
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    • pp.214-217
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    • 1996
  • Early decision support systems (DSS) were the "passive" decision support systems in the sense that the systems only able to do what the users explicitly direct them to do. But some researchers such as Raghav Rao et al. [51 showed architectures to suggest general idea of the innovative DSS systems which offer active form of decision support, say, "active Intelligent Decision Support Systems(active IDSS)". The system can perform not only what the users want to do but some voluntary (or involuntary) intelligent works. This paper presents the issues in the design of the active IDSS in the domain of investment evaluation, a domain area where few researchers have suggested frameworks or architectures to discriminate good investment from bad one. We propose a new paradigm, by utilizing historical investment results using neural network and Multivariate Discriminant Analysis(MDA), to identify goodness of investment. A new active IDSS architecture which consists of neural network, expert system and three components of the traditional passive DSS is suggested with some scenario based results.nario based results.

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Detailed Design of an Active Rotor Blade for Reducing Helicopter Vibratory Loads

  • Natarajan, Balakumaran;Eun, Won-Jong;Shin, Sang-Joon
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2011.10a
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    • pp.236-241
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    • 2011
  • An active trailing-edge flap blade named as Seoul National University Flap (SNUF) blade is designed for reducing helicopter vibratory loads and the relevant aeroacoustic noise. Unlike the conventional rotor control, which is restricted to 1/rev frequency, an active control device like the present trailing-edge flap is capable of actuating each individual blade at higher harmonic frequencies i.e., higher harmonic control (HHC) of rotor. The proposed blade is a small scale blade and rotates at higher RPM. The flap actuation components are located inside the blade and additional structures are included for reinforcement. Initially, the blade cross-section design is determined. The aerodynamic loads are predicted using a comprehensive rotorcraft analysis code. The structural integrity of the active blade is verified using a stress-strain recovery analysis.

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Development of High Frequency Active Filter for Multimedia (멀티미디어용 고주파 Active Filter개발에 관한 연구)

  • 윤종남
    • Journal of the Microelectronics and Packaging Society
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    • v.9 no.1
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    • pp.1-7
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    • 2002
  • The purpose of this work is to develop High-Frequency Active Filter and super-miniaturation technology(SMD Type) of Filter which are essential for the key R/F Microwave components in the Mobile telecommunication system. The cut-off frequency of high frequency active filter for multimedia is 2.5 MHz, the gain is 0.5dB at 100 kHz, the passband ripple is 1.2 dB max at 100 kHz~2.0 kHz, GDT is 60 nsec at 100 kHz-2.0 MHz, the attenuation is 40 dB min at 3.75 MHz.

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Over Current Protection Schemes for Active Filters with Series Compensators

  • Lee, Woo-Cheol;Lee, Taeck-Kie
    • KIEE International Transaction on Electrical Machinery and Energy Conversion Systems
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    • v.4B no.3
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    • pp.134-145
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    • 2004
  • This paper presents and analyses protection schemes for a series active compensator, which consists of a Unified Power Quality Conditioner (UPQC) or a hybrid active power filter. The proposed series active compensator operates as a high impedance "k(D)" for the fundamental components of the power frequency during over current conditions in the distribution system. Two control strategies are proposed in this paper. The first strategy detects the fundamental source current using the p-q theory. The second strategy detects the fundamental component of the load current in the Synchronous Reference Frame (SRF). When over currents occur in the power distribution system momentarily, the proposed schemes protect the series active compensator without the need for additional protection circuits, and achieves excellent transient response. The validity of the proposed protection schemes is investigated through simulation and compared with experimental results using a hybrid active power filter systems.

Concept Design of an Active Steering Bogie for Urban Railway Vehicles (도시형 전동차용 능동조향대차의 개념설계)

  • Park, Joon-Hyuk;Hur, Hyun-Moo;Koh, Hyo-In;You, Won-Hee
    • Journal of the Korean Society for Railway
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    • v.10 no.6
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    • pp.709-716
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    • 2007
  • An active steering bogie has been theoretically proved to improve both stability and steering performance remarkably. However, It has not been commercialized yet even though many researchers have been trying to develop it because some technical difficulties still exist such as information acquisition fer active control, increasing mechanical components, high energy consumption, fail-safe problem and so on. To solve those problems, an advanced active steering mechanism is proposed in this paper. With this mechanism, required control force is small enough to use direct drives. Therefore, the number of additional mechanical components can be minimized since mechanical transducers like gears are not necessary. Fail-safe function can be also inserted easily. In this paper, concept design of the proposed active steering bogie is introduced and the possibility is verified through computer simulation using linear dynamic model.

A Study on the Image of Uniforms of Female Flight Attendants (항공사 여승무원 유니폼에 관한 이미지 연구)

  • Lee, Hwa-Jin;Kim, Yoon-Kyung;Lee, Kyung-Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.29 no.9_10 s.146
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    • pp.1265-1273
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    • 2005
  • The objective of this study is to examine the images of the current uniforms and to provide the basic references in designing female flight attendants uniforms. In Incheon International Airlines, 11 of the major airlines with the most passengers along with the highest capacity were chosen and 22 pieces of photographs were collected, two photos coming from each airline companies. The semantic differential scale has been formed by 16 pairs of adjectives. Then, it has conducted a statistical analysis using a SPSS WINDOWS that contains 475 copies of the selected questionnaires (375 of the non-flight attendants, and 100 of the female flight attendants). The following are the results and the conclusion of this study. According to this study, four main components of the uniforms of the female flight attendants were attractiveness, femininity, noticeability, and activity, which have occupied $65.9\%$ of the total variance. It was concluded that attractiveness and femininity were two main factors in perceiving the females' uniforms. According to the results of the uniform image difference, it was shown that Asiana Airline's uniform is the most attractive and Cathay Pacific Airline uniform is the most feminine. The most noticeable uniform was from Singapore airline which included cultural and traditional components of its own national colors. Pants suits of Lufthansa airline and Northwest airline were shown as the most active uniforms. There were significant differences in uniform images according to subjects' gender, age, education, and occupation. Men perceived uniforms more attractive, feminine, and active than women. People over 40 perceived uniforms more attractive, feminine, and active, and the High School graduates perceived uniforms more feminine and active. On occupational basis, Federal workers and Educators perceived uniforms more active on uniforms. Passengers who take planes once a month perceived uniforms more attractive, feminine, and active.

3.5-Inch QCIF AMOLED Panels with Ultra-low-Temperature Polycrystalline Silicon Thin Film Transistor on Plastic Substrate

  • Kim, Yong-Hae;Chung, Choong-Heui;Moon, Jae-Hyun;Lee, Su-Jae;Kim, Gi-Heon;Song, Yoon-Ho
    • ETRI Journal
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    • v.30 no.2
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    • pp.308-314
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    • 2008
  • In this paper, we describe the fabrication of 3.5-inch QCIF active matrix organic light emitting display (AMOLED) panels driven by thin film transistors, which are produced by an ultra-low-temperature polycrystalline silicon process on plastic substrates. The over all processing scheme and technical details are discussed from the viewpoint of mechanical stability and display performance. New ideas, such as a new triple-layered metal gate structure to lower leakage current and organic layers for electrical passivation and stress reduction are highlighted. The operation of a 3.5-inch QCIF AMOLED is also demonstrated.

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Seasonal Changes in Biochemical Components of the Adductor Muscle and Visceral Mass Tissues in the Female Cyclina sinensis, in Relation to Gonad Developmental Phases (암컷 가무락조개, Cyclina sinensis의 난소 발달단계에 따른 폐각근 조직과 내장낭 조직의 생화학적 성분의 계절적 변화)

  • Chung, Ee-Yung;Park, Kwan-Ha;Kim, Jong-Bae;Lee, Chang-Hoon
    • The Korean Journal of Malacology
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    • v.20 no.1
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    • pp.85-92
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    • 2004
  • We investigated the reproductive cycle with gonadal development of the female Cyclina sinensis by histological observations and seasonal changes in biochemical components of the adductor muscle and visceral mass tissues were studied by biochemical analysis, from January to December, 2001. The reproductive cycle of this species can be classified into five successive stages: early active stage (February to April), late active stage (March to June), ripe stage (May to August), partially spawned stage (July to October) and spent/inactive stage (September to February). Total protein contents in the adductor muscle tissues reached the maximum in February (early active stage) and appeared the minimum in June (ripe stage), while their contents in the visceral mass tissues reached the maximum in the late active and ripe stages (June) and gradually decreased from July (partially spawned stage) to November (spent/inactive stage). Changes in total protein contents showed a negative correlationship between the adductor muscle and visceral mass tissues (r = -0.499, p = 0.099). Total lipid contents in the adductor muscle tissues reached the maximum in January (the inactive stages) and their contents gradually decreased from February. Their contents in the visceral mass tissues, however, reached the maximum in June (late active and ripe stage) and gradually decreased from July (the partially spawned stage). On the whole, total lipid contents showed a negative correlationship between the adductor muscle and visceral mass tissues (r = -0.631, p < 0.05). Therefore, These results indicate that the nutrient contents of the adductor muscle and visceral muscle tissues change in response to gonadal energy needs. Glycogen contents in the adductor muscle tissue reached the maximum in March (early and late active stages) and decreased from July to September (partially spawned stage). while their contents in the visceral mass tissues reached the maximum in June (late active and ripe stages) and gradually decreased from July (partially spawned stage). Thereafter, their levels gradually increased in November (spent/inactive stage). On the whole, changes in glycogen contents appeared negative correlationship between the adductor muscle and visceral mass tissues. However, they showed no significant different (r = -0.307, p = 0.331).

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Terahertz Transmission Imaging with Antenna-Coupled Bolometer Sensor (안테나 결합형 볼로미터 방식 테라헤르츠 센서를 이용한 이차원 주사 방식의 투과형 테라헤르츠 영상 취득에 관한 연구)

  • Lee, Kyoung Il;Lim, Byung Jik;Won, Jongsuk;Hong, Sung Min;Park, Jae Hyoun;Lee, Dae Sung
    • Journal of Sensor Science and Technology
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    • v.27 no.5
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    • pp.311-316
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    • 2018
  • An antenna-coupled bolometer-type terahertz sensor was designed, fabricated, evaluated, and utilized to obtain terahertz transmission images. The sensor consists of a thin film bowtie antenna that resonates accordingly in response to an incident terahertz beam, a heater that converts the applied current in the antenna into heat, and a microbolometer that converts the rise in temperature into a change in resistance. The device is fabricated by a bulk micromachining process on a 4-inch silicon wafer. The fabricated sensor chip has a size of $2{\times}2mm$ and an active area of $0.1{\times}0.1mm^2$. The temperature coefficient of resistance (TCR) of the bolometer film (VOx) is 2.0%, which is acceptable for bolometer applications. The output sensor signal is proportional to the power of the incident terahertz beam. Transmission images were obtained with a 2-axis scanning imaging system that contained the sensor. The small active area of the sensor will enable the development of highly sensitive focal plane array sensors in terahertz imaging cameras in the future.