• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.26 no.5
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• pp.239-248
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• 2023

Purpose: The parents of adolescents with inflammatory bowel disease may experience impaired mental health and quality of life. This longitudinal study aimed to verify whether the mental health and quality of life of the parents of adolescents with inflammatory bowel disease declined when their children had active disease. Methods: Sociodemographic data, parental anxiety, depression, and quality of life were analyzed using validated questionnaires for each variable. After the baseline survey, the second and follow-up surveys were conducted at 3 and 12 months, respectively. The active disease group comprised eight parents whose children had active disease during the baseline and second surveys. The remission group comprised 14 parents whose children remained in remission during both surveys. The improved group comprised nine parents whose children experienced active disease at baseline and remission during the second survey. Parental mental health and quality of life were compared among the groups. Results: Significantly higher levels of anxiety were observed in the active disease group in all surveys (p<0.050). Although depression levels and quality of life did not differ significantly among the three groups, pairing the active disease group with other groups showed some large effect sizes. Conclusion: Parents tended to experience decreased mental health and quality of life when their adolescents experienced active inflammatory bowel disease. Consequently, our hypothesis was partially verified. Therefore, parents need support when their children have active disease; this finding highlights the need for parental support systems.

• Journal of Microbiology and Biotechnology
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• v.24 no.5
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• pp.719-723
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• 2014

Caspases are a family of cysteine proteases that play an important role in the apoptotic pathway. Caspase-6 is an apoptosis effector that cleaves a variety of cellular substrates. The active form of the enzyme is required for use in research. However, it has been difficult to obtain sufficient quantities of active caspase-6 from Escherichia coli. In the present study, we constructed a caspase-6 with a 23-amino-acid deletion in the pro-domain. This engineered enzyme was expressed as a soluble protein in E. coli and was purified using affinity resin. In vitro enzyme assay and cleavage analysis revealed that the engineered active caspase-6 protein had characteristics similar to those of wild-type caspase-6. This novel method can be a valuable tool for obtaining active caspase-6 that can be used for screening caspase-6-specific substrates, which in turn can be used to elucidate the function of caspase-6 in apoptosis.

• Journal of the Optical Society of Korea
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• v.18 no.6
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• pp.793-798
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• 2014

To generate finite-power Airy beams, a novel holographic method is proposed. We record the interference pattern between an Airy beam (signal beam) and plane wave (reference beam) on a photopolymer, then decode the hologram by illuminating with the reference beam. The reconstructed beams still present the non-diffraction, acceleration, and self-healing features of optical Airy beams. In addition, angular multiplexing of two Airy beams with opposite acceleration directions is presented.

• Analytical Science and Technology
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• v.5 no.4
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• pp.359-366
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• 1992

Using micro-Raman spectrometer, we investigated the evaluation of microstress on silicon surface after the local thermal oxidation. The induced stress of silicon surface after local thermal oxidation shows maximum value at the interface of silicon oxide and active area. The smaller the size of active area, the larger stress. From the evaluation of three other device isolation processes, A, B and moB, whose active size has $0.45{\mu}m$ in length, moB process is turned out to have the lowest stress value and the smallest bird's beak effect.

• Journal of the Korean Society for Precision Engineering
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• v.30 no.10
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• pp.1051-1059
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• 2013

In general, lateral ride comfort of railway vehicle is mainly influenced by a secondary suspension placed between the bogie and carbody. Higher operating speeds of train results in increased vibration of carbody, which has a negative impact related to the ride comfort. To solve this problem, researches to replace the conventional passive suspension with (semi)active technology in the secondary suspension of a railway vehicle have been carried out. The semi-active suspension using the magneto-rheological damper is relatively simpler system and has advantage in maintenance compared to the hydraulic type semi-active damper. This study was performed to reduce lateral vibration acceleration of carbody related to ride comfort of railway vehicles with a semi-active suspension system. The numerical analysis was conducted by replacing passive lateral damper with semi-active MR damper, and robust control with the MR damper was applied to the 1/5 scaled railway vehicle model.

• Proceedings of the KIPE Conference
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• 2003.07a
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• pp.73-76
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• 2003

A zero voltage soft switching inverter using active clamp is presented for induction heating application. This converter have long been attractive because of its simplicity, high efficiency, and low cost compared to other schemes. In addition to those merits, Input power factor can be improved with a variable frequency control. In this paper, it describe the control method and operational principle to improve a power factor with a single stage US converter using active clamp for induction heating application.

• Proceedings of the IEEK Conference
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• 2002.07a
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• pp.345-348
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• 2002

A complementary VHF CMOS active inductor is described. The proposed circuit employs 'p-type' and 'n-type' active inductor to obtain enlarged signal handling ability. Under the same inductance, Q value, and power consumption, the proposed circuit shows more than 12-㏈ improvement in dynamic range while maintaining high-frequency operation. Further enhancement is obtained by using a fully differential floating inductor structure. A 1-㎓ 4$\^$th/-order coupled-resonator filter is designed to demonstrate the potential of the proposed active inductor.

• The Transactions of the Korean Institute of Power Electronics
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• v.18 no.5
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• pp.477-484
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• 2013

This paper proposes a novel switching method of active clamp snubber for efficiency improvement of PV module integrated converter(MIC) system. Recently, MIC solar system is researched about the efficiency and safety. PV MIC system is used active clamp method of snubber circuit for the price and reliability of the system. But active clamp snubber circuit has the disadvantage that system efficiency is decreased for switch operating time because of heat loss of resonant between snubber capacitor and leakage inductance. To solve this problem, this paper proposes a novel switching method of the active clamp. The proposed method is a technique to reduce power consumption by reducing the resonance of the snubber switch operation time and through simulations and experiments proved the validity.

• Korean Journal of Materials Research
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• v.25 no.3
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• pp.132-137
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• 2015

The effects of the mixing of an active material and a conductive additive on the electrochemical performance of an electric double layer capacitor (EDLC) electrode were investigated. Coin-type EDLC cells with an organic electrolyte were fabricated using the electrode samples with different ball-milling times for the mixing of an active material and a conductive additive. The ball-milling time had a strong influence on the electrochemical performance of the EDLC electrode. The homogeneous mixing of the active material and the conductive additive by ball-milling was very important to obtain an efficient EDLC electrode. However, an EDLC electrode with an excessive ball-milling time displayed low electrical conductivity due to the characteristic change of a conductive additive, leading to poor electrochemical performance. The mixing of an active material and a conductive additive played a crucial role in determining the electrochemical performance of EDLC electrode. The optimal ball-milling time contributed to a homogeneous mixing of an active material and a conductive additive, leading to good electrochemical performance of the EDLC electrode.

• Journal of Life Science
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• v.12 no.6
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• pp.682-687
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• 2002

We analyzed improvement on the enzyme activity of CPase Taq by addition of various metal ions. The enzyme activity was increased more then four times by 1 mM cobalt ion and almost three times by 1 mM calcium ion. However, the active center metal zinc ion did not affect the enzyme activity. In order to investigate whether the active center metal affects the enzyme activity, zinc ion which is occupied the active center of the enzyme was replaced by cobalt ion which activates the enzyme activity very effectively. Since the cobalt ion in the active center of the cobalt-substituted CPase Taq did not affect the enzyme activity, it could act as the natal metal ion in the active center of the enzyme.