• 한국건축시공학회:학술대회논문집
• /
• 한국건축시공학회 2021년도 봄 학술논문 발표대회
• /
• pp.289-290
• /
• 2021

The PC system has advantages in terms of project management, such as shortening the construction period and reducing costs. However, it is difficult to activate the technology due to insufficient application of the technology. Therefore, there is a need for a strategy to expand and activate the PC system. This study is a basic research for PC construction project management, and its purpose is to derive the entire construction process from factory production of PC components to on-site construction. In this study, the construction process of the PC system was derived through literature review, and the main matters for the construction process management of PC system were confirmed in the analysis process. In the future, the results of this study are expected to be used as basic data for research for PC project management, such as deriving construction classification and calculating construction periods.

• 한국디자인학회:학술대회논문집
• /
• 한국디자인학회 2003년도 봄 학술발표대회논문집
• /
• pp.16-17
• /
• 2003

• 건축사
• /
• 통권615호
• /
• pp.160-163
• /
• 2020

• 한국작물학회:학술대회논문집
• /
• 한국작물학회 2020년도 추계학술대회
• /
• pp.153-153
• /
• 2020

• Journal of Microbiology and Biotechnology
• /
• 제27권10호
• /
• pp.1855-1866
• /
• 2017

The synergistic activation mediator (SAM) system can robustly activate endogenous gene expression by a single-guide RNA. This transcriptional modulation has been shown to enhance gene promoter activity and leads to epigenetic changes. Human $interferon-{\gamma}$ is a common natural glycoprotein involved in antiviral effects and inhibition of cancer cell growth. Large quantities of high-purity $interferon-{\gamma}$ are important for medical research and clinical therapy. To investigate the possibility of employing the SAM system to enhance endogenous human $interferon-{\gamma}$ with normal function in innate immunity, we designed 10 single-guide RNAs that target 200 bp upstream of the transcription start sites of the $interferon-{\gamma}$ genome, which could significantly activate the $interferon-{\gamma}$ promoter reporter. We confirmed that the system can effectively and highly activate $interferon-{\gamma}$ expression in several humanized cell lines. Moreover, we found that the $interferon-{\gamma}$ induced by the SAM system could inhibit tumorigenesis. Taken together, our results reveal that the SAM system can modulate epigenetic traits of non-immune cells through activating $interferon-{\gamma}$ expression and triggering JAK-STAT signaling pathways. Thus, this strategy could offer a novel approach to inhibit tumorigenesis without using exogenous $interferon-{\gamma}$.

• 한국진공학회:학술대회논문집
• /
• 한국진공학회 2015년도 제49회 하계 정기학술대회 초록집
• /
• pp.158-158
• /
• 2015

Myoblast are myogenic precursors that proliferate, activate, and differentiate on muscle injury to sustain the regenerative capacity of skeletal muscle; The neuronal isoform of nitric oxide synthase (nNOS, termed also NOS-I) is expressed in normal adult skeletal muscle, suggesting important functions for Nitric oxide (NO) in muscle biology1,2,3. However, the expression and subcellular localization of NO in muscle development and myoblast differentiation are largely unknown. In this study, we examined effects of the nitric oxide generated by a microwave plasma torch, on proliferation/differentiation of rat myoblastic L6 cells. Experimental data pertaining to nitric oxide production are presented in terms of the oxygen input in units of cubic centimetres per minute. The various levels of nitric oxide are observed depending on the flow rate of nitrogen gas, the ratio of oxygen gas, and the microwave power4. In order to evaluate the potential of nitric oxide as an activator of cell differentiation, we applied nitric oxide generated from the microwave plasma torch to L6 skeletal muscles. Differentiation of L6 cells into myotubes was significantly enhanced the differentiation after nitric oxide treatment. Nitric oxide treatment also increase the expression of myogenesis marker proteins and mRNA level, such as myogenin and myosin heavy chain (MHC), as well as cyclic guanosine monophosphate (cGMP), However during the myotube differentiation we found that NO activate oxidative stress signaling erks expression. Therefore, these results establish a role of NO and cGMP in regulating myoblast differentiation and elucidate their mechanism of action, providing a direct link with oxidative stress signalling, which is a key player in myogenesis. Based on these findings, nitric oxide generated by plasma can be used as a possible activator of cell differentiation and tissue regeneration.

• 산경연구논집
• /
• 제8권6호
• /
• pp.61-73
• /
• 2017

Purpose - Aviation control, navigation, and aircraft control in the air transportation area are very specialized. Each part is in progress for safety, efficiency, automation, and further. On the other hand co-work among each part including knowledge sharing has been inattentive for many reasons. The purpose of this research is to show how practicians and professionals in the air transportation area perceive the issue of knowledge sharing and to recall the necessity of knowledge sharing in the area. And we try to find ways to activate the knowledge sharing in the area. Research design, data, methodology - For the research, we inquired into whether practicians and professionals think knowledge sharing can effect safe aviation positively or not and what steps are necessary to activate knowledge sharing in the area. We adopted survey method using questionnaires for current practicians and interview for specialists. The survey and interview results were analyzed using regression analysis and AHP method. The interview for specialists and analyzing the results using AHP was to investigate what are the precedence factors to activate the knowledge sharing. Results - First, practicians perceive that knowledge sharing will affect aviation safe positively. Second objective knowledges such as, tower air traffic control procedure of aviation control area, flight principle and structure of aircraft control area, instrument landing system of navigation area, for knowledge sharing of each area were identified. Also the precedence factors such as, knowledge absorbability of personal factor, personal expectation of result of expectation factor, leadership of management of Structure factor, method of knowledge spread of application factor for knowledge sharing were found. Conclusions - Knowledge sharing for practicians and professionals in the aviation area is very important especially from the perspective of safety. However, for various many reasons including the environment of each special area that focusing on their own area, knowledge sharing has not been emphasized. We found that practicians in the area feel that knowledge sharing is necessary and helpful. For it, each practician's active participation is the most important and many ways such as chatting room to share knowledge are to be developed. And the organization culture should be changed to encourage knowledge sharing.

• 대한교통학회지
• /
• 제23권5호
• /
• pp.93-104
• /
• 2005

최근 제시되고 있는 역 중심 개발모델은 저밀확산형 도시에 적용할 수 있는 모델이므로, 고밀다핵도시를 지향하는 서울시에서는 적용이 어렵다. 이러한 배경에서, 본 연구는 서울시 역세권 지구단위계획의 운영실태를 분석하여 역 중심 개발정책의 문제점을 분석하고, 대중교통이용률이 높은 싱가폴 홍콩의 역 중심 개발정책을 분석하여 서울시의 역 중심 개발 유도방안을 제시하였다. 우선은 고용중심 역세권과 근린중심 역세권의 역 중심 개발방안을 달리 마련해야 하며, 고용기능을 육성할 필요가 있는 역세권을 대중교통 중심의 전략 육성중심지로 지정할 것을 제시하였다. 또한, 역 주변 낙후지역의 정비를 유도하여 복합개발 및 환승시설을 설치할 수 있도록, 재개발사업 추진이 가능한 균형발전촉진지구로 지정하고, 환승시설 설치를 촉진할 수 있는 인센티브제도 도입을 제시하였다.

• 한국조경학회지
• /
• 제31권5호
• /
• pp.31-42
• /
• 2003

This study looked at worked on remaining landscapes in terms of landscape ecology. It presented some ways to conserve and to activate remaining landscapes with examples of agricultural lands in Hwa-won Gun, Ok-po Myun. The results are as follows: We investigated 20 remaining landscape types and 90 remaining landscapes, and classified them in terms of forest and water zones. To evaluate the investigated remaining landscapes, we produced a grading system using 8 criteria such as vitality, stability, field suitability, type of inner scenery formation, connection, recreation, and culture/tradition. Our evaluation of the vitality found that Grade I had the mast remaining landscapes; Grade II had 28, Grade III had 16, Grade V had four, and Grade IV had none. We evaluated the outer landscape influence using 3 criteria such as divisibility, vitality, and indication. We found from evaluating the type of inner scenery formation that most of the landscapes superior to Grade III were adjacent to water zones and that linear landscapes evaluated as Grade I, and II played an important role in this connection. We evaluated the recreation probability using marks, frequencies, and emergencies of peculiar types. Based on the results, we proposed some ways to conserve and to activate the remaining landscapes classified by grades using the results of the last evaluation. Additionally, we proposed some ways to activate the restoration of the linear axis of the green space function the formation of a buffer green space around matric space, the improvement of the axis of the green space center, and the formation of additional green tracts of land to play the role of stepping stones. We proposed the possibility of improving uniformed farm land structures. This study did not consider the weighting values of the evaluation index. Therefore a more objective study will be needed with an expert-survey in the future.

• 한국건축시공학회지
• /
• 제18권1호
• /
• pp.59-65
• /
• 2018

라돈가스는 암석이나 토양 등에 존재하는 자연 방사성 물질인 우라늄이 붕괴할 때 발생하는 무색, 무취, 무미의 가스이다. 인체가 연간 노출되는 방사선의 85%는 자연 방사선에 의한 것이고, 그 중 50%가 라돈가스이다. 미국 환경보호청(EPA)의 조사결과에 의하면, 라돈가스에 장시간 노출될 경우 흡연자는 1,000명 중 62명, 비흡연자는 1,000명 중 7명이 폐암 발병률에 노출된다. 이러한 라돈가스의 위해성을 저감하고자 활성탄소를 사용하여 경화체를 제작하여 그에 대한 공극 특성과 라돈가스 저감 특성에 대한 실험을 진행하였다. 활성탄소를 활용하였을 경우, 측정기간이 길어질수록 라돈가스 농도는 급격한 저감과 그래프 상의 변화를 확인할 수 있었다. 또한 활성탄소의 재료적 특성 중 하나인 공극 분포와 미세공 특성을 파악할 수 있다.