• 대한약학회:학술대회논문집
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.173-174
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• 2002

Oxidative modification of cellular structures and functions by redox imbalance is the basis of the current oxidative stress hypothesis of aging. The experimental support for this hypothsis has been generated from recent molecular probing on the interrelation between the age-related functional impairments and the pathogenesis. (omitted)

• 한국응용약물학회:학술대회논문집
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• 한국응용약물학회 1996년도 춘계학술대회
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• pp.202-202
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• 1996

The antihistaminic action of eighteen herbal medicines was investigated by the radioligand binding and functional assays. The hexane fractions of Trichosanthis radix, Mori cortex radicis and Evodiae fructus dose-dependently inhibited [$^3$H]mepyramine binding to H$_1$ receptor and histamine-induced contraction in guinea-pig brain homogenates and isolated guinea-pig ilea, respectively. Antihistaminic action of the hexane and ethylacetate fractions of Mori cortex radicis and the hexane fraction of Evodiae fructus was more potent than their antimuscarinic action evaluated from the inhibition of [$^3$H]QNB binding and carbachol response. The ethylacetate and chloroform fractions and six known flavonoids from Scutellariae radix also inhibited histamine-induced contraction, but antihistaminic potencies of these fractions and compounds were almost identical with their antimuscarinic potencies. The hexane fractions of Mori cortex radicis and Evodiae fructus, as shown in ketotifen, inhibited selectively the increase of cutaneous vascular permeability induced by histamine. However, wogonin (SC-1) from Scutellariae radix was a nonselective inhibitor for the effect of histamine and serotonin on the vascular permeability. These results demonstrate that the hexane and ethylacetate fractions of Mori cortex radicis and the hexane fraction of Evodiae fructus have the selective histamine H$_1$ receptor blocking activities.

• Journal of Dairy Science and Biotechnology
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• 제37권3호
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• pp.187-195
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• 2019

Seeds and leaves of Raphanus raphanistrum subsp. sativus (radish) are known to contain "raphanin," which has the potential to inhibit pathogenesis associated with foodborne pathogenic bacteria and fungi. In this study, ethanol extracts from R. raphanistrum subsp. sativus (radish) powder was evaluated for antimicrobial action against 6 different foodborne pathogenic bacteria. The current study demonstrated the potential of R. raphanistrum subsp. sativus (radish) in inhibiting the growth of Salmonella enteritidis 110, Cronobacter sakazakii KCTC 2949, Bacillus cereus ATCC 10876, and Staphylococcus aureus ATCC 6538. However, these antimicrobial action were not observed against Listeria monocytogenes ATCC 51776 and Escherichia coli 23716. Hence, this study indicates that R. raphanistrum subsp. sativus (radish) could be used as a natural biopreservative with antimicrobial effects for improving food safety, and as a functional food in the commercial food industry.

• 패션비즈니스
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• 제17권4호
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• pp.124-139
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• 2013

Teenage girls under the influence of the physical changes due to the rapid physical development and appearance are interested. 200 parts were used for the statistical analysis of this research against the common excitation high school student positioned in Seoul. First, there was lots of the girl student managing the appearance due to the psychological satisfaction. And the girl student without the friend of the opposite sex managed the appearance at the psychological satisfaction. Because to be more important, thing including the studying, and etc. was the priority the girl student who doesn't the appearance management did not do the appearance management. Second, the factor found out over one month allowance 50,000 circle to be the very important factor through the beauty action high of the high beauty product concern degree and girl student action of the beauty product concern degree and girl student where there is the friend of the opposite sex. Third, the more the concern degree about the beauty product was high as the concern degree about the beauty was high, the girl student in high school could know that beauty action was high as the concern degree about the multi function beauty product was high.

• International Journal of Advanced Culture Technology
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• 제10권4호
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• pp.383-388
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• 2022

This thesis explores the principle of a performer's organic action by means of his/her bodily responses on stage. This research has been developed to define the nature of a performer's central task in order to constitute empirical understanding of acting and the purpose of training in addressing the question of what sort of qualitative bodily training is necessary to be in a state of the full body involvement. This study investigates to articulate a performer's fundamental task at the most rudimentary level by utilizing those theatre artists' concepts with practical assumptions. In particular, the key terms, happen and change signifies the quality of a performer's body that has to fit into the given environment in which the performer's body can be subordinated through the moment on stage. Here, we argue that a performer's essential task parallel to make the following moment to happen and change by means of progressing a set of the next moment. In this manner, we also argue that a moment of displaying the performer's conscious effort, forceful and externalizing the visible elements under the use of erroneous language leads his/her body not to function on stage, a state of disengagement from his/her body. Finally, we provide a way to facilitate a performer's organic action by focused on his/her lived experience to create the functional moment which is opposite to the predominance of a representation, maintaining the performer's intellectual sense.

• 한국전문물리치료학회지
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• 제19권1호
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• pp.86-93
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• 2012

The purpose of this study was to assess the feasibility of task-oriented arm training for chronic hemiparetic stroke patients. The experimental design in this study was the pre-test and post-test with control group for 4-week intervention. Thirty patients with chronic hemiparetic stroke were recruited from 2 rehabilitation units. The subjects were divided randomly into experimental and control groups. The experimental group conducted task-oriented approach, involving 3 subparts of upper extremity activities, and the control group involved in the general upper extremity exercises. Functional movements of the upper extremities were assessed using clinical measures, including the Fugl-Meyer Assessment-Upper Extremity Section, Box and Block Test, and Action Research Arm Test. The score of Fugl-Meyer Assessment showed greater increases in the experimental group than in the control group after training. The improvement in Box and Block Test between pre-test and post-test measurements was significantly greater after task-oriented arm training compared to general upper extremity exercises. Action Research Arm Test scores also improved after task-oriented arm training compared to exercises in the control group. The task-oriented arm training improves the gross and fine motor activities and encouraging the use of the paretic arm through activity dependent intervention expedites the recovery of functional activities in the upper extremities for chronic hemiparetic stroke.

• 한국생활과학회지
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• 제6권1호
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• pp.111-127
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• 1997

This study was to examine home economics (HE) teachers' and the 1st-grade students' needs perception toward the purposes of HE education in middle school which has been practced since 1995 for both male and female students. This study, attempted (1) to analyze needs priority among the educational purposes of HE subject in relation to three systems of actions; (2) to compare differences between HE teachers' and students' perception concerning the degree of importance and achievement of the educational purposes of HE subject: and (3) to examine what they conceive as the problems In the current HE education. The survey was conducted with the samples of 600 1st-grade middle school students and 101 middle school HE teachers during the period of February-March 1996. The questionnaire used in this study was a modified version which had already been developed along with the 6th HE curriculum. For data analyses, SAS program was utilized to get Means and to perform both discrepancy test and t-test. The findings of this study were summarized as follows: first, with respect to each group's perception of the importance of the purposes related to three systems of action, HE teachers emphasized the importance of the purposes related to emancipatory action, while students placed more emphasis on the purposes related to technical action. Second, in terms of the degree of achievement, students had more positive perception on the degree of achievement of the purposes related to technical action than HE teachers did. Both groups marked low level of recognition on the degree of achievement of the purposes related to emancipatory action. Third, with respect to needs priority, HE teachers placed the first priority on emancipatory action, the second on technical action, and the last on communicative action: in the case of students, the first priority was on technical action, the second on communicative action, and the last on emancipatory action. In addition, the analysis of the opinions on the 6th curriculum revealed that most respondents found it necessary to secure adequate amount of classes for HE education. Also they shared the recongnition that HE curriculum should be renovated into the one which would fully appreciate the purposes of HE education from the perspective of the practical concerns of action which are distinct from the functional and technical concerns of passive learning. The findings of this study can serve as basic data for establishing the new purposes of HE education which put more emphasis on the purposes related to emancipatory action: as well as for developing an enhanced curriculum and reinforcing the identity of HE education.

• 복식문화연구
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• 제8권4호
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• pp.517-536
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• 2000

The purpose of this study is to investigate the internal and external line beauty of men's dress of the Chosun period from the views of dress design and dress aesthetics. 1) External Line Beauty of Men's Dress of the Chosun Period ① Functional Beauty : Having the beauty of functional line in terms of convenience, action, effectiveness, practivce and sanitation. ② Structural Beauty : Having the beauty harmonizing between lines of internal and external structures. ③ Ornamental Beauty : Having the beauty of simple line by matching accessories (gat, fan, sejodae, shoes) with a simple dress. ④ Wearing Beauty : Making tall-looking or expressing a mature masculine beauty by a visual mistake caused by a combination of internal and external structural beauty lines. 2) Internal Line Beauty of Men's Dress of the Chosun Period Including a simple but natural beauty based on natural philosophy, the beauty of courtesy emphasizing official hat and dress and the beauty of dress having aesthetic consciousness with which people enjoy an idyllic life.

• 대한후두음성언어의학회지
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• 제28권2호
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• pp.71-78
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• 2017

Voice disorder is classified into three categories, structural, neurogenic and functional dysphonia. Neurogenic dysphonia refers to a disruption in the nerves controlling the larynx. Common examples of this include complete or partial vocal cord paralysis, spasmodic dysphonia. Also it occurs as part of an underlying neurologic condition such as Parkinson's disease, myasthenia gravis, Lou Gehrig's disease or disorder of the central nervous system that causes involuntary movement of the vocal folds during voice production. Functional dysphonia is a voice disorder in the absence of structual or neurogenic laryngeal characteristics. A near consensus exist that Muscle tension dysphonia (MTD) is functional voice disorder wherein hyperfunctional laryngeal muscle activity whereas Spasmodic dysphonia (SD) is neurogenic, action-induced focal laryngeal dystonia including several subtype. Both Adductor type spasmodic dysphonia (AdSD) and MTD may be associated with excessive supraglottic contraction and compensation, resulting in a strained voice quality with spastic voice breaks. It makes these two disorders extremely difficult to differentiate based on clinical interpretation alone. Because treatment for AdSD and MTD are quite different, correct diagnosis is important. Clinician should be aware of the specific vocal characteristics of each disease to improve therapeutic outcome.

• Genomics & Informatics
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• 제12권4호
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• pp.225-230
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• 2014

Platelets are derived from the fragments that are formed from the cytoplasm of bone marrow megakaryocytes-small irregularly shaped anuclear cells. Platelets respond to vascular damage, contracts blood vessels, and attaches to the damaged region, thereby stopping bleeding, together with the action of blood coagulation factors. Platelet activation is known to affect genes associated with vascular risk factors, as well as with arteriosclerosis and myocardial infarction. Here, we performed a genome-wide association study with 352,228 single-nucleotide polymorphisms typed in 8,842 subjects of the Korea Association Resource (KARE) project and replicated the results in 7,861 subjects from an independent population. We identified genetic associations between platelet count and common variants nearby chromosome 4p16.1 ($p=1.46{\times}10^{10}$, in the KIAA0232 gene), 6p21 ($p=1.36{\times}10^{-7}$, in the BAK1 gene), and 12q24.12 ($p=1.11{\times}10^{-15}$, in the SH2B3 gene). Our results illustrate the value of large-scale discovery and a focus for several novel research avenues.