• Journal of Pharmaceutical Investigation
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• v.31 no.3
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• pp.181-184
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• 2001

The purpose of this study was to develop transdermal drug delivery system (TDDS) for the combination of physostigmine and procyclidine. The effects of various pressure sensitive adhesives (PSA) on the percutaneous absorption of procyclidine across hairless mouse skin were evaluated to select an appropriate PSA. In addition, the influences of various vehicles on the percutaneous absorption of procyclidine from PSA matrix across hairless mouse skin were evaluated using flow-through diffusion cell system at $37^{\circ}C$. Physostigmine did not have any influence on the permeation rate of procyclidine. The flux of procyclidine was the highest in silicone and PIB and was relatively lower in SIS, Acryl, and SBS adhesive matrices, however, their use was limited by the crystallization of the drug in the matrix. Among acrylic adhesives, the permeability of procyclidine was the highest from poly (ethylene oxide) grafted acrylic adhesive. Some enhancers show different enhancing effect depending on the drug, however, many of the tested enhancers showed enhancing effect for the permeation of both procyclidine and physostigmine to some extent. $Crovol^{\circledR}$ EP 40 showed the highest enhancing effect on the permeation of both compounds. The size of TDDS to provide required permeation rate was estimated to be $35\;cm^2$ based on available information.

• Journal of the Korea Institute of Building Construction
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• v.6 no.4 s.22
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• pp.85-92
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• 2006

Urethane, epoxy, acrylic have common property to adhere on the concrete dried surface in the waterproofing materials at present. In the wet condition, however, the materials such as urethane, epoxy, acrylic need a long hardening time and it become a reason of water leakage as the materials breaking down. it is one of the problem to adhere to the substrate. Therefore, in this thesis, I focused to assure the structural safety and durability and quality for waterproofing and safe of construction cost by cut down the cost of labor and reduce the term of works as searching the application of field condition for high adhesive spray type of degenerated and rubberized asphalt membrane material.

• Journal of the Korean Wood Science and Technology
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• v.35 no.1
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• pp.44-50
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• 2007

The objective of this study was to investigate the influence of the vehicle resin on the coating performance of Dan-Chung. The starch glue (F), fish glue (G), and aqueous acrylic resin emulsion (E) were used as vehicle resins. Panels coated with Dan-Chung were tested at accelerated weathering and outdoor conditions. Aqueous acrylic resin was proved as an excellent vehicle resin for Dan-Chung, because there was no flaking in Dan-Chung film after accelerated weathering and outdoor exposure. Discoloration of Dan-Chung using E was the smallest among the acceleratedly weathered panels. Adhesive property of Dan-Chung film using G was. remarkably improved by G-undercoating. On the contrary, G-undercoating lowered adhesive property of Dan-Chung film using E.

• Polymer(Korea)
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• v.33 no.1
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• pp.45-51
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• 2009

Water soluble adhesive was polymerized from butyl acrylate (BA), methyl methacrylate (MMA) and one of various functional monomers such as acrylic acid (AA), 2-hydroxylethyl methacrylate (2-HEMA), glycidyl methacrylic acid (GMA) and acrylamide (AAm). The amount of the functional monomers was 1$\sim$5 wt%/monomer. In order to improve the adhesive power, a substrate was treated using atmospheric flat plasma method. The adhesive power was improved by the addition of the functional monomers with an order of AA> 2-HEMA> GMA> AAm. The holding power of the adhesives, which is related with the thermal properties of the adhesives, increased with the amount of the functional monomers. The effectiveness in improving the holding power has an order of AA > AAm > GMA > 2-HEMA. By treating a substrate with atmospheric flat plasma method, the adhesives containing each of AA, 2-HEMA, GMA and AAm showed the increases of the final adhesion strength by 9.1, 9.4, 9.4, and 1.8%, respectively. In conclusion, the mechanical properties such as adhesive power and holding power could be controlled by introducing.

• Journal of Adhesion and Interface
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• v.21 no.4
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• pp.135-142
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• 2020

Recently, people's interest in eco-friendly plastics derived from nature to replace petroleum-based plastics is increasing due to environmental problems such as microplastics. In line with this trend, eco-friendly adhesives using natural materials and processes are also being developed in the adhesive field. Among them, maltose is a natural substance derived from starch and is the main component of starch syrup used as a food additive. Due to its lower molecular weight than starch, it is easily soluble in water, and above all, there is a possibility that it can be copolymerized with other monomers through solution polymerization. However, researches related to the application of maltose to adhesives are very rare. In this study, after modifying maltose using acrylic anhydride, the product was analyzed through FT-IR and H-NMR. And the modified maltose was copolymerized with two kinds of acrylic monomers. The synthesized adhesive was applied on the wood and the adhesive performance were investigated.

• Journal of Adhesion and Interface
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• v.20 no.4
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• pp.135-139
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• 2019

In this work, flame retardant acrylic emulsion pressure sensitive adhesives were newly polymerized combining phosphorous flame retardant monomer and acrylic monomer like butyl acrylate, 2-ethylhexyl acrylate, methyl methacrylate, acrylic acid, and 2-hydroxyethyl methacrylate. The process of polymerization showed 100% of conversion at solid content of 65%, and viscosity of acrylic emulsion was increased up to 5500 cps when phosphorous flame retardant monomer was added into acrylic emulsion. The structure of flame retardant acrylic emulsion was identified using FT-IR and thermal properties like glass transition temperature (Tg) were checked by differential scanning calorimeter (DSC). Acrylic emulsion without phosphorous flame retardant monomer had Tg of -44.1℃ and peel strength of 2,100gf/inch, however, flame retardant acrylic emulsion showed maximum Tg (-31.4℃) and peel strength of 200gf/inch when 15 part of phosphorous flame retardant monomer was added. Flammability test was also conducted to confirm the application of flame retardant acrylic emulsion as the flame retardant addtive.

• Polymer(Korea)
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• v.32 no.4
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• pp.313-321
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• 2008

Acrylic pressure sensitive adhesive(PSA) was prepared by UV radiation curing and the peel energy and physical properties of PSA were investigated. The increase of amount of acrylic acid leads to improve the peel energy, associated with the substrate having smooth surface and high layer thickness. The high peel energy is obtained when the direction of irregularity in substrate is horizontal with the peeling direction. This is attributed to the increase of resistance to peeling in spite of decrease of wetting and the result corresponds to our supposition.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2009.10a
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• pp.695-696
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• 2009

• Proceedings of the Korean Institute of Building Construction Conference
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• 2017.11a
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• pp.35-36
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• 2017

This study used Geopolymer to study tile waterproofing adhesives. The materials used in this study were polymer and acrylic resin, and were evaluated based on adhesion and water resistance. In particular, the adhesion was evaluated under various conditions, and the substrate was comparatively evaluated on the concrete and tile surface conditions.

• Korean Chemical Engineering Research
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• v.48 no.5
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• pp.609-614
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• 2010

In this study, emulsion polymerizations for synthesizing acrylic pressure-sensitive adhesive(PSA) were carried out using 2-ethylhexyl acrylate(2-EHA), n-butyl acrylate(n-BA), methyl metacrylate(MMA) as fundamental monomers and acrylic acid(AAc) as a functional monomer in the presence of anionic SLS (sodium lauryl sulfate). To obtain the optimized synthetic condition in the polymerization, we analyzed the polymerization variables such as the effect of surfactant concentration and hydrophilic lipophilic values(HLB). At the same time, the final adhesive properties were also analyzed by the function of the initiator concentration and buffer concentration. In the results, the most stable emulsion was obtained at the surfactant concentrations between 3 and 5 wt%. It was also determined the effect of HLB value of nonionic surfactant and the initiator concentrations on the gel content. Stable emulsion is obtained using the surfactant having HLB value of 12.3. The rate of emulsion polymerization was increased at the initiator concentration greater than 1 wt%, but the stability of the emulsion was decreased. Finally, the effect of the buffer concentrations on the pH and the conversion of the acrylic emulsion product were experimentally measured. At the sodium bicarbonate concentration above 0.4 wt%, the buffer infulence was apparent. The buffer effect was fully acceptable at the concentrations between 0.6 and 0.8 wt% regardless of the monomer composition.