• Title/Summary/Keyword: acquisition process

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Use of Real-Time Quantitative PCR to Identify High Expressed Genes in Head and Neck Squamous Cell Carcinoma Cell Lines

  • Lee, Yong-Gyoo;Chun, So-Young;Lee, Hae-Ahm;Sohn, Yoon-Kyung;Kang, Ku-Seong;Kim, Joung-Ok;Yun, Sang-Mo;Kim, Jung-Wan;Jang, Hyun-Jung
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.32 no.1
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    • pp.69-75
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    • 2006
  • Head and neck squamous cell carcinoma(HNSCC) is the sixth most common cancer among men in the developed world affecting the tongue, pharynx, larynx and oral cavity. HNSCC is thought to represent a multistep process whereby carcinogen exposure leads to genetic instability in the tissue and accumulation of specific genetic events, which result in dysregulation of proliferation, differentiation, and cell loss and the acquisition of invasive capacity. Despite therapeutic and diagnostic progress in oncology during the past decades, the prognosis of HNSCC remains poor. Thus it seems that finding a biological tumor markers which will increase the early diagnosis and treatment monitoring rates, is of paramount importance in respect to improving prognosis. In an effort to identify gene expression signatures that may serve as biomarkers, this study several genes were selected, such as H3,3A, S100A7, UCHL1, GSTP1, PAI-2, PLK, TGF${\beta}$1 and bFGF, and used 7 HNSCC cell lines that were established various anatomical sites, and also 17 other cancer cell lines were used for control group using real-time quantitative RT-PCR and immunocytochemical analysis with a monoclonal antibody. In this study, S100A7 showed a clearly restricted occurrence in tongue originated cell line, and GSTP1 expression level in the pharynx originated cell line was very increased, relative to corresponding other cell lines. These results suggest that S100A7 and GSTP1 genes' expression can occur during tongue and pharynx originated head and neck tumorigenesis and that genetic change is an important driving force in the carcinogenesis process. This data indicate that S100A7 and GSTP1 expression pattern in HNSCC reflect both diagnostic clue and biological marker. And this is provides a foundation for the development of site-specific diagnostic strategies and treatments for HNSCC.

Generation of the Ortho-Rectified Photo Map and Analysis of the Three-Dimensional Image Using the PKNU 2 Imagery (PKNU2호 영상을 이용한 정사영상 지도 제작 및 3차원 입체 분석)

  • Lee, Chang Hun;Choi, Chul Uong
    • Journal of the Korean Association of Geographic Information Studies
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    • v.7 no.4
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    • pp.77-87
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    • 2004
  • It is important for hydrographers to extract the accurate cross section of a river for the hydrographical analysis of the topography. Aerial photographs were used to extract the cross section of a river for the advantages of the accuracy and economical efficiency in this study, while the direct measurement has been used in existing studies. An ortho-rectified photo map using imageries taken by the PKNU 2 (High-resolution, multi-spectral, aerial photographic system developed by our laboratory) was generated using the surveyed data and a digital map. The cross section of a river that was obtained from the ortho-rectified by the surveyed Kinematic data of GPS was compared with the result using ImageStation stereo-plotter of corp. Z/I Imaging. As a result of this study, the RMSE in the ortho-rect process using the surveyed GPS data was lowered as from 5.5788 pixels (about 2m) to 2.84 (about 1m) in comparison with it in the process using a digital map. The surveyed kinematic GPS in extraction of the cross section of a river was excellent as 6.6cm of the planimetric and precision in the confidence level of 95%. The correlation coefficient between the result from the using stereo-plotter and the extraction of cross section of a river using aerial photos was 0.8 hydrographical acquisition of it using PKNU 2 imagery will be possible.

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The LVC Linkage for the Interoperability of the Battle Lab (Battle Lab에서의 상호운용성을 위한 LVC 연동방안)

  • Yun, Keun-Ho;Shim, Shin-Woo;Lee, Dong-Joon
    • Journal of the Korea Society for Simulation
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    • v.21 no.1
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    • pp.81-88
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    • 2012
  • In the M&S filed, The Battle Lab is available for acquisition, design, development tool, validation test, and training in the weapon system of development process. Recently, the Battle Lab in the military of Korea is still in an early stage, in spite of importance of battle lab construction. In the environment of network centric warfare, a practical use of the M&S which is connecting live, virtual and constructive model can be applied to all field of System Engineering process. It is necessary thar the Battle Lab is not restricted by time and space, and is possible for the technical implementation. In this paper, to guarantee the interoperability of live and virtual simulation, virtual simulators connect live simulators by using the tactical data link. To guarantee the interoperability of virtual and constructive simulation, both virtual simulators and constructive simulators use the RTI which is the standard tool of M&S. We propose the System that constructed the Air Defence Battle Lab. In case of the approach of target tracks, The Air Defence Battle Lab is the system for the engagement based on a command of an upper system in the engagement weapon system. Constructive simulators which are target track, missile, radar, and launcher simulator connect virtual simulators which are MCRC, battalion, and fire control center simulators using the RPR-FOM 1.0 that is a kind of RTI FOM. The interoperability of virtual simulators and live simulators can be guaranteed by the connection of the tactical data links which are Link-11B and ATDL-1.

Validation of the Developed Evaluation Method for Competition Intelligence of Sport Talented Children (체육영재의 영재성 평가도구에 대한 타당도 검증)

  • Kim, Kwang-Hoi;Kim, Won-Hyun;Kim, Do-Youn
    • Journal of Digital Convergence
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    • v.15 no.2
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    • pp.465-473
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    • 2017
  • The purpose of this study was to verify the validity of the developed evaluation method for competition intelligence of sport talented children of of Kim et al.(2015). For this purpose, total 3 times of observation by sports leaders were accomplished for evaluation of competition intelligence. After finishing final observation, the correlation between the sub-factors(practice intelligence, learning intelligence, and training intelligence) and gifted students' physical fitness and KOSTASS were examined. First, as the reliability, the correlations between leaders' observation results were significantly higher than 0.8 in all sub-factors. Second, all sub-factors of competition intelligence showed significant positive correlation with in standing jump, 50m dash and side step test improvement(p<.05). Third, all sub-factors showed no significant correlation with KOSTASS(p>.05). These results showed that the evaluation tool by Kim et al.(2015) didn't not fully reflect the improvement level of basic physical fitness factors of the gifted students. However, the results of correlation between physical fitness factors requiring technical learning process showed that the gymnastic gauging tools included learning process and task acquisition level.

Accurate Camera Calibration Method for Multiview Stereoscopic Image Acquisition (다중 입체 영상 획득을 위한 정밀 카메라 캘리브레이션 기법)

  • Kim, Jung Hee;Yun, Yeohun;Kim, Junsu;Yun, Kugjin;Cheong, Won-Sik;Kang, Suk-Ju
    • Journal of Broadcast Engineering
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    • v.24 no.6
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    • pp.919-927
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    • 2019
  • In this paper, we propose an accurate camera calibration method for acquiring multiview stereoscopic images. Generally, camera calibration is performed by using checkerboard structured patterns. The checkerboard pattern simplifies feature point extraction process and utilizes previously recognized lattice structure, which results in the accurate estimation of relations between the point on 2-dimensional image and the point on 3-dimensional space. Since estimation accuracy of camera parameters is dependent on feature matching, accurate detection of checkerboard corner is crucial. Therefore, in this paper, we propose the method that performs accurate camera calibration method through accurate detection of checkerboard corners. Proposed method detects checkerboard corner candidates by utilizing 1-dimensional gaussian filters with succeeding corner refinement process to remove outliers from corner candidates and accurately detect checkerboard corners in sub-pixel unit. In order to verify the proposed method, we check reprojection errors and camera location estimation results to confirm camera intrinsic parameters and extrinsic parameters estimation accuracy.

Improvement on performance management through quantitative evaluation method for technologies acquired from defense offset program (절충교역 획득기술 활용성과 정량화를 통한 성과관리 제고 방안)

  • Park, Tae-Woan;Jung, Tae-Yun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.2
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    • pp.609-618
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    • 2017
  • This paper presents the quantitative evaluation method for technologies acquired from the defense offset program. We firstly deduced the consideration in development by gathering the opinions of 128 experts by conducting a survey. Next, we made up an additional 49 experts for developing a performance management system of the offset program. The management system covered 4 technology fields which are defense R&D, depot maintenance, performance improvement, and manufacturing. The development procedure was composed of 4 parts: setting-up of work process, defining performance indicators, calculating weighted values of each indicator, and devising quantitative method. The results of this research could be used for enhancing the effectiveness of the offset program in 3 ways: establishing a systematic work process after acquisition of technology in offset program, establishing the positive feedback architecture by providing incentives to superior institute or company which is appointed through quantitative performance evaluating, and publicizing and promoting quantified outstanding performances for contributing to advance the offset program.

The Robust Skin Color Correction Method in Distorted Saturation by the Lighting (조명에 의한 채도 왜곡에 강건한 피부 색상 보정 방법)

  • Hwang, Dae-Dong;Lee, Keunsoo
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.2
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    • pp.1414-1419
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    • 2015
  • A method for detecting a skin region on the image is generally used to detect the color information. However, If saturation lowered, skin detection is difficult because hue information of the pixels is lost. So in this paper, we propose a method of correcting color of lower saturation of skin region images by the lighting. Color correction process of this method is saturation image acquisition and low-saturation region classification, segmentation, and the saturation of the split in the low saturation region extraction and color values, the color correction sequence. This method extracts the low saturation regions in the image and extract the color and saturation in the region and the surrounding region to produce a color similar to the original color. Therefore, the method of extracting the low saturation region should be correctly preceding. Because more accurate segmentation in the process of obtaining a low saturation regions, we use a multi-threshold method proposed Otsu in Hue values of the HSV color space, and create a binary image. Our experimental results for 170 portrait images show a possibility that the proposed method could be used efficiently preprocessing of skin color detection method, because the detection result of proposed method is 5.8% higher than not used it.

Range Stabbing Technique for Continuous Queries on RFID Streaming Data) (RFID 스트리밍 데이타의 연속질의를 위한 영역 스태빙 기법)

  • Park, Jae-Kwan;Hong, Bong-Hee;Lee, Ki-Han
    • Journal of KIISE:Databases
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    • v.36 no.2
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    • pp.112-122
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    • 2009
  • The EPCglobal leading the development in RFID standards proposed Event Cycle Specification (ECSpec) and Event Cycle Reports (ECReports) for the standard about RFID middleware interface. ECSpec is a specification for filtering and collecting RFID tag data and is treated as a Continuous Query (CQ) processed during fixed time intervals repeatedly. ECReport is a specification for describing the results after ECSpec is processed. Thus, it is efficient to apply Query Indexing technique designed for the continuous query processing. This query index processes ECSpecs as data and tag events as queries for efficiency. In logistics environment, the similar or same products are transferred together. Also, when RFID tags attached to the products are acquired, the acquisition events occur massively for the short period. For these properties, it is inefficient to process the massive events one by one. In this paper, we propose a technique reducing similar search process by considering tag events which are collected by the report period in ECSpec, as a range query. For this group processing, we suggest a queuing method for collecting tag events efficiently and a structure for generating range queries in the queues. The experiments show that performance is enhanced by the proposed methods.

A Study on the Measurement and Comparison(IEC 60079-32-2) of Flammable Liquid Conductivity (인화성 액체 도전율에 관한 측정 및 비교(IEC 60079-32-2) 연구)

  • Lee, Dong Hoon;Byeon, Junghwan
    • Journal of the Korean Society of Safety
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    • v.34 no.4
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    • pp.22-31
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    • 2019
  • The flammable liquid conductivity is an important factor in determining the generation of electrostatic in fire and explosion hazardous areas, so it is necessary to study the physical properties of flammable liquids. In particular, the relevant liquid conductivity in the process of handling flammable liquids in relation to the risk assessment and risk control in fire and explosion hazard areas, such as chemical plants, is classified as a main evaluation item according to the IEC standard, and it is necessary to have flammable liquid conductivity measuring devices and related data are required depending on the handling conditions of the material, such as temperature and mixing ratio for preventing the fire and explosion related to electrostatic. In addition, IEC 60079-32-2 [Explosive Atmospheres-Part 32-2 (Electrostatic hazards-Tests)] refers to the measuring device standard and the conductivity of a single substance. It was concluded that there is no measurement data according to the handling conditions such as mixing ratio of flammable liquid and temperature together with the use and measurement examples. We have developed the measurement reliability by improving the structure, material and measurement method of measuring device by referring to the IEC standard. We have developed a measurement device that is developed and manufactured by itself. The test results of flammable liquid conductivity measurement and the data of the NFPA 77 (Recommended Practice on Static Electricity) Annex B Table B.2 Static Electric Characteristic of Liquids were compared and verified by conducting the conductivity measurement of the flammable liquid handled in the fire and explosion hazardous place by using Measuring / Data Acquisition / Processing / PC Communication. It will contribute to the prevention of static electricity related disaster by taking preliminary measures for fire and explosion prevention by providing technical guidance for static electricity risk assessment and risk control through flammable liquid conductivity measurement experiment. In addition, based on the experimental results, it is possible to create a big data base by constructing electrostatic physical characteristic data of flammable liquids by process and material. Also, it is analyzed that it will contribute to the foundation composition for adding the specific information of conductivity of flammable liquid to the physical and chemical characteristics of MSDS.

A Case Study of Service Education Activities Applying Mathematics into a Place-Based Earth Science Program: Measuring the Earth's Size (수학과 연계한 장소기반 지구과학 프로그램에 대한 교육봉사활동 사례 연구: 지구의 크기 측정)

  • Yu, Eun-Jeong;Kim, Kyung Hwa
    • Journal of the Korean earth science society
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    • v.40 no.5
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    • pp.518-537
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    • 2019
  • This study examined the implications of a place-based earth science program integrated with Mathematics. 11 pre-service earth science teachers and 22 middle school students participated in the service education activities of earth science for 30 hours focusing on the measurement of the earth's size through earth science experiments as part of the middle school curriculum. In order to minimize errors that may occur during the earth's size measurement experiments using Eratosthenes's shadows length method of the ancient Greek era, the actual data were collected after triangulation ratios were conducted in the locations of two middle schools: one in remote metropolitan and the other in rural area. The two schools' students shared the final estimate result. Through this process, they learned the mathematical method to express the actual data effectively. Participants, experienced the importance and difficulty of the repetitive and accurate data acquisition process, and also discussed the causes of errors included in the final results. It implies that a Place-Based Earth Science Program activity can contribute to students' increased-understanding of the characteristics of earth science inquiry and to developing their problem solving skills, thinking ability, and communication skills as well, which are commonly emphasized in science and mathematics in the 2015 reunion curriculum. It is expected that a place-based science program can provide a foundation for developing an integrated curriculum of mathematics and science.