• Journal of Ginseng Research
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• v.17 no.3
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• pp.196-202
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• 1993

A study was performed to compare the anticancer effects of Korean and Chinese red ginseng roots. The whole crude extracts or chloroform, methanol and acetone fractions of the crude extracts were added in the culture medium of three cancer cell lines, a mouse leukemia cell line ($P_{388}$), a human colon carcinoma cell line (HT-29) and a human rectal carcinoma cell line (HRT-18), to screen the growth inhibition effects. The results are summarized as follows : 1. Crude extracts of both Korean and Chinese red ginseng roots inhibited the proliferation of all the three cancer cell lines tested in a dose dependent manner. However, the growth inhibition effects of Korean red ginseng extracts were significantly greater than that of Chinese red ginseng. 2. An acetone fraction showed the greatest antiproliferative effects among the 11'hole crude extracts, chloroform, methanol and acetone fractions of the crude extracts. 3. These results suggest that the active antiproliferative components of the crude extracts are present mostly in the acetone fraction.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1986.12a
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• pp.509.2-509
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• 1986

Owing to the growing interest in the production of fuels and chemicals from biomass the well-know butanol-acetone fermentation as carried out by Clostridium acetobutylicum has been intensely studied again in recent years. Several solvent-yielding fermentation processes were established which are operated by using batch cultures or continuous cultures. 1 could be shown that under conditions of phosphate limitation an asporogenous mutant of C. acetobutylicum establishes itself in a chemostat which produces the solvents continuously. Attempts have been made to change the butanol/acetone ratio in favor of butanol production. A corresponding shift of the product spectrum can be achieved by carbon monoxide addition to the head space of the fermentation (B.H. Kim et al., App. Envioron. Microbiol. 48, 764-770 1984) or by iron limitation. Progress has been made in understanding the mechanism underlying the shift from acid to solvent prodcction. Experimental results are in agreement with the view that intracellular accumulation of acetic and butyric acid results in a shortage of phosphate and coenzyme A. This shortage may serve then as signal for the synthesis of the enzymes involved in the formation of acetone and butanol.

• Korean Journal of Agricultural Science
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• v.39 no.3
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• pp.377-386
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• 2012

To reduce the saturation level of lard, solvent fractionation with hexane and acetone was carried out. The fatty acid compositions of lard were 1.5% myristic acid, 26.0% palmitic acid, 2.2%, palmitoleic acid, 12.1% stearic acid, 44.7% oleic acid, and 12.7% linoleic acid. Lard was fractionated by various conditions such as different fractionation temperatures (-15, 5, 10, $15^{\circ}C$), solvent ratios (1:1, 1:3, 1:5, 1:10, lard : solvent, w/v), and fractionation time (3, 6, 24 hr). At $-15^{\circ}C$, acetone was better for reducing the content (11.2%) of saturated fatty acids (SFA) than hexane (10.8%) when the 1:5 solvent ratio was used at 24 hr. Triacylglycerol (TAG) profiles were analyzed by reversed-phase high performance liquid chromatography based on the partition number (PN) of TAG molecules. The PN of major TAG species in lard were 46 (24.4%), 48 (55.7%), and 50 (19.9%). However, after fractionation (1:5, $5^{\circ}C$ and 24 hr), TAG species with a PN of 46 (34.2%), 48 (54.4%), and 50 (6.9%) were major components in acetone-fractionated lard (liquid part), while TAG species with a PN of 46 (26.0%), 48 (50.3%), and 50 (19.0%) were in hexane-fractionated lard, suggesting that fractionation with acetone resulted in maximal reduction of saturation level in lard.

• Journal of the Korea Society for Simulation
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• v.5 no.1
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• pp.43-50
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• 1996

2-propanol/acetone/hydrogen 반응계로 구성된 화학적 열펌프 시스템은 낮은 온도(82.5~$90^{\circ}C$)에서의 2-propanol의 탈수소화 반응과 높은 온도(약 $200^{\circ}C$ 부근)에서의 acetone의 수소화반응을 이용하여 열을 고품위화 시키는 장치이다. 본 연구에서는 이 시스템의 해석 및 설계를 목적으로 이 시스템에 대한 수치적인 모델들을 세우고 Sequential modular approach를 이용하여 시스템의 모사를 수행하였다. 또한 에너지 효율을 최대화하기 위하여 열펌프 시스템에서의 환류비의 영향을 규명하였다. 모사결과 이 시스템의 scale up을 위한 정량적인 정상상태 운전조건들을 구할수 있었으며 두 반응의 반응 전화율이 다르더라도 반응물의 유량의 차이를 통하여 두 반응열이 거의 같아지는 것을 알수 있었다. 아울러 주어진 운전조건에서 증류의 환류비는 최소환류비 근처의 최적값이 존재함을 알수 있었다.

• Mycobiology
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• v.38 no.4
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• pp.295-301
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• 2010

We evaluated the antioxidant activity and tyrosinase inhibitory effects of Pleurotus ostreatus fruiting bodies extracted with acetone, methanol, and hot water. The antioxidant activities were tested against $\beta$-carotene-linoleic acid, reducing power, 1,1-diphenyl-2-picrylhydrazyl free radical scavenging activity, and ferrous chelating ability. Furthermore, phenolic acid and flavonoid contents were also analyzed. The methanol extract showed the strongest $\beta$-carotene-linoleic acid inhibition as compared to the other exracts. The acetone extract (8 mg/mL) showed a significantly high reducing power of 1.54 than the other extracts. The acetone extract was more effective than other extracts for scavenging on 1,1-diphenyl-2-picrylhydrazyl radicals. The strongest chelating effect (85.66%) was obtained from the acetone extract at 1.0 mg/mL. The antioxidant activities of the extracts from the P. ostreatus fruiting bodies increased with increasing concentration. A high performance liquid chromatography analysis detected seven phenolic compounds, including gallic acid, protocatechuic acid, chlorogenic acid, naringenin, hesperetin, formononetin, and biochanin-A in an acetonitrile and 0.1 N hydrochloric acid (5 : 1) solvent extract. The total phenolic compound concentration was $188{\mu}g$/g. Tyrosinase inhibition of the acetone, methanol, and hot water P. ostreatus extracts increased with increasing concentration. The results revealed that the methanol extract had good tyrosinase inhibitory ability, whereas the acetone and hot water extracts showed moderate activity at the concentrations tested. The results suggested that P. ostreatus may have potential as a natural antioxidant.

• Korean Chemical Engineering Research
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• v.56 no.3
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• pp.376-380
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• 2018

The astaxanthin recovery efficiencies were compared in acetonitrile, acetone, methanol, dichloromethane : methanol (1:3, v/v) and ethylacetate : ethanol (1:1, v/v) as a extraction solvent after the grinding of the H. pluvialis cells. The astaxanthin extraction yield in acetone was 1.13~1.29 times higher than other extraction solvents. It was also found that 96.7% of astaxanthin accumulated in H. pluvialis could be recovered by a single extraction. Since astaxanthin exists mainly as astaxanthin esters in H. pluvialis, a gradient reversed-phase HPLC analysis was carried out for the separation of astaxanthin esters from the extracts of H. pluvialis. Among the astaxanthin inside the H. pluvialis cell, free astaxanthin was 45.9% and astaxanthin esters were the rest.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.26 no.3
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• pp.301-306
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• 2016

Objectives: Direct-reading instrument(Photoionization detectors, PID) and quantitative analysis using active type air sampling (Gas chromatography-flame ionization detector, GC-FID) were tested to evaluate their ability to detect volatile organic compounds(VOCs) in a semiconductor manufacturing plant. Methods: The organic compounds used were acetone and ethanol which are normally used as cleaning solutions in the semiconductor manufacturing. The evaluation was based on the preparation of test solutions of known acetone and ethanol concentration in a chamber($600{\times}600{\times}1150mm$). Samples were prepared that would be equivalent to 5~100 ppm for acetone and 10~ 200 ppm ethanol. GC-FID and PID were evaluated simultaneously. Quantitative analysis was performed after sampling and the direct-reading instrument was checked using real-time data logging. Results: Positive correlations between PID and GC-FID were found for acetone and ethanol at 0.04~2.4% for acetone(TLV: 500 ppm) and 0.1~8.3% for ethanol(TLV: 1000 ppm). When the sampling time was 15 min, concentration of test solution was the most similar between measurement methods. However, the longer the sampling time, the less similar the results. PID and GC-FID had similar exposure patterns. Conclusions: The results indicate that PID and GC-FID have similar exposure pattern and positive correlation for detection of acetone and ethanol. Therefore, PID can be used for exposure monitoring for VOCs in the semiconductor manufacturing industry. This study has significance in that it validates measuring occupational exposure using a portable device.

• Korean Journal of Food Science and Technology
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• v.17 no.2
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• pp.95-100
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• 1985

Effects of number of washings with solvents on drying rates and physicochemical properties of dried soymilk residues(SMR) were investigated. The dried soymilk residue was prepared by washing the residue with acetone or ethanol, followed by drying at $60^{\circ}C$. Increase of number of washings with a residue/solvent ratio of 1/1.5 resulted in an increase in drying rate and in protein content of the residue while the lipid content decreased. The brightness of the dried residue and the properties of water and oil absorption were also improved by washing with acetone which was advantageous to ethanol for all of the properties measured. Washings more than 3 times with acetone or 2 times with ethanol were found to be less effective in terms of quality improvement. The more addition of dried residue into the mixture of SMR-wheat flour resulted in a linear increase of water and oil absorption characteristics.

• Applied Chemistry for Engineering
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• v.19 no.5
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• pp.539-546
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• 2008

A study on the selection of an optimal entrainer as the third component among water, aniline, 1,3-diethylbenzene, furfural, and MEK, for the extractive distillation of an azeotropic acetone/methanol system was performed using both the entrainer effect vapor-liquid equilibrium (VLE) and the relative volatility. In the case of water as the entrainer, a VLE curve without azeotropic point in the range of water composition from 0.3 up to 0.7 mole fraction could be obtained by both the experiment and the calculation using modified-UNIFAC model. For aniline and 1,3-diethylbenzene, however, VLE curve without azeotropic point could be obtained only at compositions above 0.7 mole fraction, which exhibited that they could be hardly utilized as the entrainer. Moreover, both furfural and MEK were verified to be improper entrainer since they formed an azeotropic phase. Relative volatility of water showed greater than 1.0 and increased with compositions, while those of the others decreased non-linearly, exhibiting that only water could be utilized as the proper entrainer for the extractive distillation of azeotropic acetone/methanol system.

• Journal of Environmental Science International
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• v.16 no.3
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• pp.377-383
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• 2007

In this study, the relationship between the pore size distribution and the adsorption amount of adsorbates is investigated in detail. Adsorption amounts of non-polar adsorbates were greater than those of polar adsorbates because of slight negative charge on surfaces of adsorbents. The adsorption of benzene on the surface of absorbents was largely influenced by the specific pore size of $2{\sim}4$ times of benzene diameter. But in case of toluene, the adsorption of toluene was affected by pore sizes of $2{\sim}4$ times as well as $4{\sim}6$ times of the diameter of toluene. Both acetone and MEK were examined by the same method. The adsorption of acetone was influenced by pore sizes of $2{\sim}4$ times of the diameter of acetone. But acetone does not look to be built up multi-layer on those pore sizes. Since acetone molecule is small and its mobility is so fast, it is assumed that the adsorption and desorption of acetone is simultaneously occurred at the same time even at room temperature. In case of MEK, MEK was effected by pore sizes of $2{\sim}4$ times of the diameter of MEK.