• Journal of the Korean Institute of Landscape Architecture
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• v.46 no.3
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• pp.103-116
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• 2018

The Park Act (1967~1980) was the first law to define urban parks in Korea. The urban parks of that time were similar to a reservation area used for other purposes after giving regulation. Because 'the urban park as a reservation area' in the past is a repeated park issue in the present, it is necessary to consider the issues of the original law system that created the cause. From this perspective, this study analyzed the legislation to reserve an urban park by collecting bills and information about the factual relationship between 1960 70s park issues and the Park Act. Analysis showed that the reason for the adoption of different kinds of urban parks in the law of a nature park is that a negative list separated from the Urban Planning Act is required to curb private usage. Inherent in the Park Act, however, was the problem of allowing the encroachment of urban parks by governmental power. (1) The Park Act sets out a wide range of cases to abolish urban park. (2) Unclear setting of governmental power could abuse the urban park. (3) Insufficient standards were able to erode the urban park with large for-profit facilities. (4) The inactivity of the Urban Public Park Committee had reduced democratic decision-making and professional judgement on park issues. Therefore, the Park Act was characterized as infringing on the environment and right to urban parks and took a passive attitude in creating parks and in citizen usage thereof. The Park Act had limitations as a progenitor for establishing the characteristics and concepts of urban parks.

• Journal of KIISE:Software and Applications
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• v.31 no.8
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• pp.1092-1100
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• 2004

An E-mails have regarded as one of the most popular methods for exchanging information because of easy usage and low cost. Meanwhile, exponentially growing unwanted mails in user's mailbox have been raised as main problem. Recognizing this issue, Korean government established a law in order to prevent e-mail abuse. In this paper we suggest hybrid spam mail filtering system using weighted Bayesian classifier which is extended from naive Bayesian classifier by adding the concept of preprocessing and intelligent agents. This system can classify spam mails automatically by using training data without manual definition of message rules. Particularly, we improved filtering efficiency by imposing weight on some character by feature extraction from spam mails. Finally, we show efficiency comparison among four cases - naive Bayesian, weighting on e-mail header, weighting on HTML tags, weighting on hyperlinks and combining all of four cases. As compared with naive Bayesian classifier, the proposed system obtained 5.7% decreased precision, while the recall and F-measure of this system increased by 33.3% and 31.2%, respectively.

• Clinical and Experimental Pediatrics
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• v.49 no.5
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• pp.489-493
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• 2006

Purpose : The purpose of this study was to determine those factors which could contribute to the development of necrotizing enterocolitis(NEC) in fullterm. Methods : We retrospectively reviewed the medical record of 20 full-terms with NEC(${\geq}$modified Bell's staging criteria IIa) who were admitted to the Neonatal Intensive Care Unit of Il Sin Christian hospital from January 1998 through July 2005, and for each case, the next 2 healthy newborns were matched as controls. Results : Mean gestational age and birth weight in the fullterm with NEC group was 38.42 weeks and 2,915 g; in the healthy fullterm without NEC group, it was 38.61 weeks and 3,148 g. When compared with the control group, NEC infants had a significantly higher frequency of chorioamnionitis, protracted diarrhea. As for Apgar score at 1 min <7, respiratory problem, congenital heart disease. there were no differences in frequency of preeclampsia, maternal diabetes, maternal drug abuse, meconium-stained amniotic fluid, polycythemia or exchange transfusion. Conclusion : Most of these full term infants have a predisposing factor before developing NEC. Our study suggested that NEC in fullterm infants was significantly associated with protracted diarrhea, and congenital heart disease.

• Toxicological Research
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• v.17
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• pp.47-57
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• 2001

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, and its pathology is characterized by the presence of numerous numbers of senile plaques and neurofibrillary tangles. Several genetic and transgenic studies have indicated that excess amount of $\beta$-amyloid protein (A$\beta$) is produced by mutations of $\beta$TEX>$\beta$-amyloid precursor protein and causes learning impairment. Moreover, $A\beta$ has a toxic effect on cultured nerve cells. To prepare AD model animals, we have examined continuous (2 weeks) infusion of $A\beta$ into the cerebral ventricle of rats. Continuous infusion of $A\beta$ induces learning impairment in water maze and passive avoidance tasks, and decreases choline acetyltransferase activity in the frontal cortex and hippocampus. Immunohistochemical analysis revealed diffuse depositions of $A\beta$ in the cerebral cortex and hippocampus around the ventricle. Furthermore, the nicotine-evoked release of acetylcholine and dopamine in the frontal cortex/hippocampus and striatum, respectively, is decreased in the $A\beta$-infused group. Perfusion of nicotine (50 $\mu\textrm{M}$) reduced the amplitude of electrically evoked population spikes in the CA1 pyramidal cells of the control group, but not in those of the $A\beta$-infused group, suggesting the impairment of nicotinic signaling in the $A\beta$-infused group. In fact, Kd, but not Bmax, values for ［$^3H$］ cytisine binding in the hippocampus significantly increased in the $A\beta$-infused rats. suggesting the decrease in affinity of nicotinic acetylcholine receptors. Long-term potentiation (LTP) induced by tetanic stimulations in CA1 pyramidal cells, which is thought to be an essential mechanism underlying learning and memory, was readily observed in the control group, whereas it was impaired in the $A\beta$-infused group. Taken together, these results suggest that $A\beta$ infusion impairs the signal transduction mechanisms via nicotinic acetylcholine receptors. This dysfunction may be responsible, at least in part, for the impairment of LTP induction and may lead to learning and memory impairment. We also found the reduction of glutathione- and Mn-superoxide dismutase-like immunoreactivity in the brains of $A\beta$-infused rats. Administration of antioxidants or nootropics alleviated learning and memory impairment induced by $A\beta$ infusion. We believe that investigation of currently available transgenic and non-transgenic animal models for AD will help to clarify the pathogenic mechanisms and allow assessment of new therapeutic strategies.

• The Journal of the Korea Contents Association
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• v.13 no.12
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• pp.715-723
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• 2013

Following the social consensus for the need to stop sexual violence, the government has amended juvenile sex protection laws to impose fees on education practitioners who do not report sexual crimes against women, and amended the 'domestic violence prevention and victim protection laws' (2012. 2) so that the police can investigate on site. However, regardless of these wide efforts, the reality is that sexual crimes against the socially weak do not seem to be dwindling, raising concerns of the effectiveness of such amendments. Generally sexual crimes are hard to prove, and even if reports are filed, most cases are dropped with non-prosecution disposition. Victims are usually limited to women and children and this leads to secondary victims. As this thesis states, developed countries have a more systematic protection methods than our country. Therefore, the purpose of this thesis lies on the construction of public safety infrastructure for the protection of sexual abuse victims (enhancing safety protocols with related organizations, implementing a bill of rights for the victims, prevention-centered police education, amendments to current law) to limit human rights violations and criminal injuries.

• Korean Journal of Clinical Laboratory Science
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• v.48 no.4
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• pp.335-342
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• 2016

Staphylococcus aureus, which is generally susceptible to the involvement route in community, is mostly MSSA. However, CA-MRSA is recently increased. Abuse of antibiotics and glycopeptides may increase VISA and VRSA. This study was conducted to investigate the changes on the antibiotic resistance prevalence and antibiotic susceptibility patterns of Staphylococcus aureus isolated from the wound of patients in a university hospital for the past 10 years. This study showed that antibiotic resistance was higher in males than in females; moreover, the antibiotic resistance rates increased with age. The resistance rate for penicillin, oxacillin, erythromycin, gentamicin, clindamycin, tetracycline, ciprofloxacin, fusidic acid, trimethoprim/sulfamethoxazole, clindamycin, and rifampicin was, respectively, 97.7%, 60.5%, 57.4%, 48.8%, 41.1%, 44.2%, 44.2%, 14.7%, 13.2% and 3.9% in 2006. The resistance rate for penicillin, oxacillin, erythromycin, gentamicin, clindamycin, tetracycline, ciprofloxacin, fusidic acid, trimethoprim/sulfamethoxazole, fusidic acid, clindamycin, and rifampicin was, respectively 95.9%, 62.6%, 55.7%, 28.6%, 50.3%, 34.7%, 38.8%, 34.0%, 2.7% and 8.2% in 2016. Vancomycin, linezolid, quinupristin/dalfopristin, and teicoplanin exhibited 100% in antibiotic susceptibility. In particular, fusidic acid resistance was increased by 19.3% in 2016. Compared with 2006, the decreased point, 12.4% was susceptible and was statistically significant. Therefore, this study suggests that periodic review and understanding of microbial and antibiotic changes should continue to investigate appropriate antibiotic susceptibility.

• The Journal of the Korea Contents Association
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• v.17 no.11
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• pp.632-640
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• 2017

Purpose: This study was to investigate the difference of attitude toward caring for alcoholics of nursing college students according to degree of parents' drinking problem. Methods: The subjects of this study were 281 students in the second and fourth grade students in nursing departments of 4 Universities located in G city. Data were analyzed by the mean and standard deviation, t-test. and ANOVA using SPSS 22.0 program.. Results: Parents' problem drinking perceived by the subjects was $3.70({\pm}5.85)$, $1.25({\pm}1.71)$ in the social drinking group(n=225), $8.59({\pm}2.07)$ in the alcohol abuse group(n=29), and alcohol dependence group (n=27) was $18.85({\pm}5.17)$ points. The average attitude toward caring for alcoholics was $45.25({\pm}6.49)$. The attitude toward caring for alcoholics showed a statistically significant difference depending on whether or not-they participated in the nursing practice of alcoholics. The attitude toward caring for alcoholics in nursing college students was negative as the parents' problem drinking was severe. Conclusion: The results of this study can be used as basic data for the development of psychiatric nursing education and counseling program for nursing college students whose parental drinking problems are serious in the future.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.2
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• pp.311-317
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• 2018

The purpose of this study is to identify the needs of the nursery director, teachers, parents, and the general public regarding the use of mandatory CCTV. In other words, we will examine the benefits, problems, and solutions of mandatory CCTV. The subjects of this study included families, private day care centers, private presbytery, kindergartens, teachers, parents and the general public in D metropolitan city. The research tools were modified and supplemented questionnaires appropriately for the study purpose with reference to the previous research. Collected data was analyzed by frequency and F-test using SPSS 21.0 program. The main results of this study are as follows: First, the benefits of mandatory CCTV for daycare centers is that CCTV becomes objective evidence of human rights incidents, identifies violence among children, and can take measures. In addition, mandatory CCTV can also reduce or prevent abuse. Second, major problems concerning the mandatory use of nursery school CCTV include privacy, violation of basic rights, and education. CCTV is a stressful factor that causes teachers to feel embarrassed, uncomfortable, and tense. Third, the main improvement measures for the nursery school CCTV mandate are to prevent unfair staff and complement existing guidelines for CCTV use. Based on the results of the study, we detail the benefits, problems, and solutions for the nursing home CCTV mandatory poli.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.7
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• pp.207-213
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• 2018

To increase the acceptance of multicultural youth, it is necessary to grasp the factors influencing multicultural acceptance. This study was conducted to provide basic data for a future study for the promotion of multicultural acceptance of adolescents by systematically analyzing research trends in factors affecting the multicultural acceptance of Korean adolescents. From 2008 to 2017, we searched 6,435 papers combining the keywords 'multicultural,' 'acceptability,' 'teenager,' 'middle school' and 'high school,' and analyzed six articles. The qualitative evaluation refers to Community Guide and STrengthening the Reporting of OBservational studies in Epidemiology(STROBE). The results revealed that factors influencing multicultural acceptance include gender, experience of overseas visits, life satisfaction, parental neglect and abuse, parent education, school and community factors, and community awareness. Multicultural acceptance of adolescents in Korea was influenced not only by specific factors, but also by various factors such as individual, family, school, and community. These factors were also found to change with age. Based on the results of this study, it is necessary to provide an environment and education that promote multicultural acceptance.

• Journal of Microbiology and Biotechnology
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• v.28 no.11
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• pp.1883-1895
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• 2018

Alcohol dependence is a global public health problem, yet the mechanisms of alcohol dependence are incompletely understood. The traditional view has been that ethanol alters various neurotransmitters and their receptors in the brain and causes the addiction. However, an increasing amount of experimental evidence suggests that gut microbiota also influence brain functions via gut-to-brain interactions, and may therefore induce the development of alcohol use disorders. In this study, a rat model of alcohol dependence and withdrawal was employed, the gut microbiota composition was analyzed by high-throughput 16S rRNA gene sequencing, and the metagenome function was predicted by PICRUSt software. The results suggested that chronic alcohol consumption did not significantly alter the diversity and richness of gut microbiota in the jejunum and colon, but rather markedly changed the microbiota composition structure in the colon. The phyla Bacteroidetes and eight genera including Bacteroidales S24-7, Ruminococcaceae, Parabacteroides, Butyricimonas, et al were drastically increased, however the genus Lactobacillus and gauvreauii in the colon were significantly decreased in the alcohol dependence group compared with the withdrawal and control groups. The microbial functional prediction analysis revealed that the proportions of amino acid metabolism, polyketide sugar unit biosynthesis and peroxisome were significantly increased in the AD group. This study demonstrated that chronic alcohol consumption has a dramatic effect on the microbiota composition structure in the colon but few effects on the jejunum. Inducement of colonic microbiota dysbiosis due to alcohol abuse seems to be a factor of alcohol dependence, which suggests that modulating colonic microbiota composition might be a potentially new target for treating alcohol addiction.