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Multifocal Motor Neuropathy (다초점성 운동신경병증)

  • Lee, Dong-Kuck
    • Annals of Clinical Neurophysiology
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    • v.4 no.2
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    • pp.98-107
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    • 2002
  • Multifocal motor neuropathy (MMN) is a chronic immune-mediated peripheral myelinopathy. The major clinical features include slowly progressive, painless, and asymmetric weakness, usually of distal limb muscle. Early in the course of the disease, weakness is not necessarily associated with muscle atrophy, owing to the initial primary involvement of peripheral myelin. Chronic progressive weakness is often associated with some degree of concurrent axonal loss and subsequent muscle atrophy. Sensory symptoms are usually mild or absent, and involvement of cranial and respiratory muscles is rare. The findings of multifocal motor conduction block, abnormal temporal dispersion, and focal conduction slowing at segments not at risk for common entrapment or compression injury, associated with normal sensory conduction studies along the same segments, are the hallmark electrophysiologic features of MMN. The slow progression and absence of upper motor neuron signs are the major clinical points that separate MMN from amyotrophic lateral sclerosis. The role of GM1 antibodies, found in high titers in 22~84% of MMN patients, remains uncertain. The contention that MMN is an autoimmune disorder is largely based on the often dramatic improvement in symptoms following the administration of intravenuos immunoglobulin or cyclophosphamide.

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Thyroiditis: Radioisotope Scan Findings and Clinical Significance (갑상선염의 방사선동위원소 검사소견 및 임상적의의)

  • Kim, Jong-Chae;Han, Duck-Sup;Park, Jung-Suck;Kim, Se-Jong;Park, Byung-Lan;Kim, Byoung-Geun
    • The Korean Journal of Nuclear Medicine
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    • v.25 no.2
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    • pp.280-285
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    • 1991
  • We analyzed Radioisotope scan findings of 46 patients of thyroiditis which were proven pathologically at K.C.H. The results were as follows 1) 45 patients were female, one was male and average age of patients was 37 years old. 2) The lesion site was predominant in both lobe (67%) 3) Hashimoto's thyroiditis showed enlarged thyroid (85%) with cold nodule (20%), diffuse decreased activity (10%), while subacute thyroiditis was presented absent activity (53%), poor visualization (20%) or cold nodule (7%) 4) Radioisotope scan was valuable in evaluations function of thyroid gland and detection of lesion but there was a limit of pathological nature.

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Influence of Weather Factors on the Incidence of the Mulberry Aleyrodid, Dialeuropora decempuncta (Quaintance and Baker) and Their Relation to Yield Loss

  • Bandyopadhyay U. K.;Santhakumar M. V.;Sahu P. K.;Saratchandra B.
    • International Journal of Industrial Entomology and Biomaterials
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    • v.11 no.2
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    • pp.129-133
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    • 2005
  • The seasonal occurrence and influence of abiotic factors viz., maximum and minimum temperature, maximum and minimum humidity and rainfall on population fluctuation of aleyrodid, Dialeuropora decempuncta on a evolved mulberry (Morus alba L.) variety known to be susceptible to aleyrodid infestation was assessed during the period from 1999 - 2001 in twenty-five villages under nine blocks of Malda district of West Bengal. The results indicate that the aleyrodid population is practically very low or absent during January to June and thereafter increases gradually. The increase in population of various stages of aleyrodid is significantly correlated with increase in previous 7 days of average maximum relative humidity.

Paraesophageal Hernia with Gastric Erosion - A Case Report - (식도주위 열공 탈장에서 병발한 위미란의 치험)

  • Baek, Hong-Gyu;Yu, Hoe-Seong
    • Journal of Chest Surgery
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    • v.26 no.4
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    • pp.337-341
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    • 1993
  • Since the first deliberate repair of hiatal hernia by Wm. J. Mayo in 1911, counterless procedure have been performed to correct herniation of the stomach into the posterior mediastinum. Recently,we experienced 51 years old female patient with large paraesophageal hernia and complete intrathoracic stomach which combined with multiple gastric erosion with chronic blood loss. So gastric ulcer within a diaphragmatic hernia is a distinct physiophathologic and clinical entity that our patient suffered from severe anemia due to chronic blood loss. The hernia was repaired transabdominally including reduction of stomach, excision of sac, closure of defect, anterior gastropexy, and gastr6stomy. Because of absent gastroesophageal refiux, no another antireflux procedure was required and erosion was managed by H2 receptor blocker.

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Unroofed Coronary Sinus Syndrome (Report of one case) (관상정맥동 천정 결손증 (치험 1례))

  • 조광현
    • Journal of Chest Surgery
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    • v.22 no.4
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    • pp.655-660
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    • 1989
  • The unroofed coronary sinus syndrome is a spectrum of cardiac anomalies in which part or all the common wall between the coronary sinus and the left atrium is absent. This defect is part of a developmental complex which includes absence of the coronary sinus and termination of a persistent left superior vena cava in the left atrium. Recognition of this complex is important so that interruption or diversion of the left superior vena cava may be done to prevent subsequent central nervous system complications. Surgical correction uses an intraatrial baffle to divert flow from the left superior vena cava to right atrium and to close the atrial septal defect. This report describes a 7 years old female patient in whom the left superior vena cava was identified preoperatively and the complex [unroofed coronary sinus syndrome, common atrium, mitral valve cleft] recognized at the time of operation. Surgical correction, following repair of cleft mitral valve, utilized a Dacron patch baffle to route the left caval blood to the right atrium and included closure of the atrial septal defect

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A Study of the hydrological generation - The generation and comparison with annual and monthly dicharge at Wacgwan in the Nakdong River (수문학적 모의기법에 대한 연구 - 낙동강 왜관지점의 연유량과 월유량의 모의발생 및 비교 -)

  • 천덕진;최영박
    • Water for future
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    • v.13 no.1
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    • pp.49-56
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    • 1980
  • The thesis of this analytical study includes 1) the generation of annual and monthly discharge regarding single hydrological variable at single site, 2)comparsion with the historical records and the generation, and 3) changing the monthly generatied discharge into annual. The conclusion of this will be used for the future plan for water resources development. Annual discharges at waegwan are characterized by log-normal distirbution and persistence-absent. Also, the random number generator causes the errors in the generation of annual discharge. The serial correlation coefficients of the generated annual discharge have less value than that of historical records, while the correlation coefficient and slope in January have(+) value and opposite to historical record. To change the monthly generated discharge into annual is not proper.

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Identification and Functional Characterization of a Cryptococcus neoformans UPC2 Homolog

  • Kim, Nam-Kyun;Han, Kyung-Hwan;Jung, Won-Hee
    • Mycobiology
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    • v.38 no.3
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    • pp.215-218
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    • 2010
  • Azoles are currently the most widely used class of antifungal drugs clinically, and are effective for treating fungal infections. Target site of azoles is ergosterol biosynthesis in fungal cell membrane, which is absent in the mammalian host. However, the development of resistance to azole treatments in the fungal pathogen has become a significant challenge. Here, we report the identification and functional characterization of a UPC2 homolog in the human pathogen Cryptococcus neoformans. UPC2 plays roles in ergosterol biosynthesis, which is also affected by the availability of iron in Saccharomyces cerevisiae and Candida albicans. C. neoformans mutants lacking UPC2 were constructed, and a number of phenotypic characteristics, including antifungal susceptibility and iron utilization, were analyzed. No differences were found between the mutant phenotypes and wild type, suggesting that the role of C. neoformans UPC2 homolog may be different from those in S. cerevisiae and C. albicans, and that the gene may have a yet unknown function.

Spinal Intradural Extramedullary Cavernoma Presenting with Intracranial Superficial Hemosiderosis

  • Jin, Yong-Jun;Chung, Sang-Bong;Kim, Ki-Jeong;Kim, Hyun-Jib
    • Journal of Korean Neurosurgical Society
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    • v.49 no.6
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    • pp.377-380
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    • 2011
  • A case of intradural extramedullary cavernous angioma is presented with headache, dizziness, and bilateral sensorineural hearing loss caused by an intracranial superficial hemosiderosis. It was incidentally found in a patient with a 3-month history of sustained headache, dizziness and a 3-year history of hearing difficulty. The neurological examination was unremarkable in the lower extremity. MR images showed an intracranial superficial hemosiderosis mostly in the cerebellar region. Myelography and MR images of the thoracolumbar spine revealed an intradural extramedullary mass, which was pathologically proven to be a cavernous angioma. T12 total laminoplastic laminotomy and total tumor removal were performed without any neurologic deficits. The patient's symptoms, including headache and dizziness, have been absent for three years. Intradural extramedullary cavernous angioma can present with an intracranial superficial hemosiderosis as a result of chronic subarachnoid hemorrhage.

Clinical study of Endocardial Cushion Defect [7 Cases Report] (심내막상 결손증의 임상적 고찰7례 보고)

  • 김승철
    • Journal of Chest Surgery
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    • v.18 no.2
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    • pp.283-287
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    • 1985
  • Seven patients had undergone repair of endocardial cushion defect from Jan. 1977 to Dec. 1984 at National Medical Center. Most patients had no associated anomalies except one who had PFO, and mortality case was absent. Five patients had partial ECD and two had complete ECD [Rastelli type A]. In P-ECD patients, the atrial septal defect was closed with patch in all cases and mitral cleft was approximated with 2-3 direct stitches. In two cases of C-ECD, atrial and ventricular septal defect was closed with single patch in one case and atrial septal defect was closed with patch but ventricular septal defect was closed with patch but ventricular septal defect was closed it direct suture in the other case. Atrioventricular cleft was approximated with 2-3 direct sutures. Postop. transient A-V block was noted in 2 cases but returned to regular sinus rhythm after 2 to 6 months.

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Composition of Okara Produced from Soymilk Processing (두유생산공정 중에 발생하는 비지의 성분에 관한 연구)

  • 우은열;이경애;이옥희;김강성
    • The Korean Journal of Food And Nutrition
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    • v.14 no.6
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    • pp.562-567
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    • 2001
  • In order to utilize okara protein as a food auditive, nutritional composition of soymilk okara was investigated. Protein in okara Is highly insoluble due to excessive heat treatment during soymilk processing. Protein content of okara was 37.3% as compared to 42.5 % for soybean. Carbohydrate and lipid contents of okara were 40.6% and 17.9%, respectively. Okara lipid extracted with chloroform-methanol consisted of neutral lipid, glycolipid and phospholipid, with neutral lipid making up 98.6% . Linoleic acid, ileic acid, and palmitic acids accounted for about 80% of the total fatty acids with linoleic acid sharing 50.3% of the total. Amino acid composition of okara protein was dissimilar to that of soy Protein : Cysteine was totally absent in okara while lysine, which is the limiting amino acid of soy protein, was present in higher amount in okara on dry weight basis. Both aqueous extract of okara protein and soy Protein were found to have ACE inhibitory activity.

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