• Title/Summary/Keyword: abnormality

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Is it Necessary to Submit Grossly Normal Looking Gall Bladder Specimens for Histopathological Examination?

  • Tayeb, Muhammad;Rauf, Fozia;Ahmad, Khurshid;Khan, Faiz Muhammad
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.4
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    • pp.1535-1538
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    • 2015
  • Background: The objectives of the study were to: 1) determine the frequency of incidental malignancy in unsuspected/grossly normal looking gall bladders; 2) determine the frequency of malignancy in suspected/grossly abnormal looking gall bladders. Materials and Methods: This prospective, cross sectional study was carried out at a tertiary care hospital in Pakistan, during a four year period (Jan 2009-dec2012). All the cholecystectomy cases performed for gallstone diseases were examined initially by a surgeon and later on by a pathologist for macroscopic abnormalities and accordingly assigned to one of the three categories i.e. grossly normal, suspicious, abnormal/malignant. Frequency of incidental carcinoma in these categories was observed after receiving the final histopathology report. Results: A total of 426 patients underwent cholecystectomy for cholelithiasis, with a 1:4 male: female ratio. Mean age of the patients was 45 years with a range of 17-80 years. The frequency of incidental gallbladder carcinoma was found to be 0.70 %(n=3). All the cases of gallbladder carcinoma were associated with some macroscopic abnormality. Not a single case of incidental carcinoma gallbladder was diagnosed in 383 'macroscopically normal looking' gallbladders. Conclusions: Incidental finding of gall bladder cancer was not observed in any of macroscopically normal looking gall bladders and all the cases reported as carcinoma gallbladder had some gross abnormality that made them suspicious. We suggest histopathologic examination of only those gall bladders with some gross abnormality.

A Method of Analyzing ECG to Diagnose Heart Abnormality utilizing SVM and DWT

  • Shdefat, Ahmed;Joo, Moonil;Kim, Heecheol
    • Journal of Multimedia Information System
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    • v.3 no.2
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    • pp.35-42
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    • 2016
  • Electrocardiogram (ECG) signal gives a clear indication whether the heart is at a healthy status or not as the early notification of a cardiac problem in the heart could save the patient's life. Several methods were launched to clarify how to diagnose the abnormality over the ECG signal waves. However, some of them face the problem of lack of accuracy at diagnosis phase of their work. In this research, we present an accurate and successive method for the diagnosis of abnormality through Discrete Wavelet Transform (DWT), QRS complex detection and Support Vector Machines (SVM) classification with overall accuracy rate 95.26%. DWT Refers to sampling any kind of discrete wavelet transform, while SVM is known as a model with related learning algorithm, which is based on supervised learning that perform regression analysis and classification over the data sample. We have tested the ECG signals for 10 patients from different file formats collected from PhysioNet database to observe accuracy level for each patient who needs ECG data to be processed. The results will be presented, in terms of accuracy that ranged from 92.1% to 97.6% and diagnosis status that is classified as either normal or abnormal factors.

Abnormality of Reproduction and Organ Structure of the Pale Chub, Zacco platypus from Isa Stream (이사천에서 채집된 피라미, Zacco platypus의 생식과 기관계 구조 이상)

  • Jin Young-Guk;Shin Soon-Ho;Lee Jae-Bong;Lee Jae-Woo;An Cheul-Min;Lee Jung-Sick
    • Environmental Analysis Health and Toxicology
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    • v.21 no.1 s.52
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    • pp.35-43
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    • 2006
  • Reproduction and organ structure of the pale chub, Zacco platypus in Isa stream were investigated by means of histological methods. The results of the study confirmed reproductive abnormality and histopathological features in the pale chub. The gonadosomatic index (GSI) of the fish showed two peak in April and August. In summer season, GSI of the male was about two times of the female's GSI. Monthly variation of the gonadal development was very irregular. From the histological analysis of the organ structure, epidermal atrophy, necrosis and hyperplasia of pigment cell were observed in the skin. Epithelial layer lifting and clubbing of the lamella and bifurcation of the filament were observed in the gill. Also histological changes as congestion, cytoplasmic degeneration of hepatic cell, degeneration of bile duct, glomerular dilatation, degeneration of renal tubule and pycnosis of interstitial cell were identified in the liver and kidney, respectively.

A Study on Aesthetic Characteristics of Modern Fur Fashion - Focused on Vogue since the 1980s - (현대 모피패션에 나타난 미적특성에 관한 연구 - 1980년대 이후 Vogue를 중심으로 -)

  • Hwang, Jae-Yun;Kim, Jeong-Mee
    • Journal of the Korea Fashion and Costume Design Association
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    • v.17 no.4
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    • pp.161-172
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    • 2015
  • In this study, characteristics of modern fur fashion were reviewed and aesthetic characteristics shown in fur fashion were analyzed. The results of this study are as follow. Aesthetic characteristics shown in fur fashion between 1980s and 2000s are conspicuousness, sensuality, elegance, activity, humor and abnormality. Conspicuousness was displayed in oversized fur coat in vivid leopard pattern, mink coat trimmed with rich fox fur or leopard patterned fur jacket in hot pink. Sensuality was displayed in white and gray soft mink coat worn over mini dress, soft mink jacket which is short enough to expose legs or soft fox best accentuating chest and arms. Elegance was displayed in soft fox coat in silver, luxurious mink coat with slim silhouette that flows with body line or silver bolero made of mink and silk with slim silhouette. Activity was presented in mink pullover with loose silhouette or rabbit jacket that emphasized functionality by having zippers or hem made of rubber. Humor was presented in unique and humorous patterned fur jacket or exaggerated and unique form of fox bolero. Abnormality was presented in mink jacket made of combining alien material with deformed proportion and form or outer that emphasized vague form by using long and big fox fur.

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A Study of Chromosomal Abnormality in Urological Patients (비뇨기과 환자에서의 염색체 이상에 관한 연구)

  • Kim, Kwang-Myung;Choi, Hwang;Oh, Sun-Kyung;Moon, Shin-Yong
    • Clinical and Experimental Reproductive Medicine
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    • v.13 no.2
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    • pp.161-174
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    • 1986
  • A chromosomal study was performed in a total of 162 urological patients during past 2$2{\frac{1}{2}}$ years (Feb. 1984 - Aug. 1986). Of these 78(48%) patients had abnormal chromosome complements. Among all patients with chromosome abnormalities, 88% (69/78) had aberrations of chromosome number, 8% (6/78) had aberrations of chromosome structure and 4% (3/78) had aberrations of both. 90% (65/72) of numerical abnormality was Klinefelter's syndrome and the structural abnormality rate (5.6%, 9/162) was less than that (6.99%) of general population. The chromosomal study was mandatory for the detection of intersex in small testes or hypospadias with cryptorchism or clitoromegaly or bilateral cryptorchism. But unilateral cryptochism or hypospadias with normal scrotal testes was not thought to be indication of the chromosomal study if the external genitalia are otherwise quite normal.

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Gonadal Abnormality and Intersexuality of Oplegnathus fasciatus (Teleostei: Oplegnathidae) Collected from the Southern Coast of Korea: A Case Report

  • Choi, Ji Sung;Shin, So Ryung;Kim, Hyeon Jin;Kim, Hyejin;Kim, Yeonghye;Lee, Jung Sick
    • Development and Reproduction
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    • v.25 no.3
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    • pp.123-131
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    • 2021
  • We report on the gonadal structure abnormality and intersexuality found from a survey regarding the reproductive potential of the rock bream, Oplegnathus fasciatus, along the southern coast of Korea. In total, 448 samples were collected for histological analysis (total length 27.5±6.8 cm; total weight 522.9±385.6 g). The sex ratio (F:M) was 1:0.46 (n=307:141), with 68.5% being females. The frequency of oocyte atresia and ovarian neoplasm in the females was 85.3% and 21.5%, respectively, and the frequency of testicular lobule and cyst deformation and testicular neoplasm in the males was 73.1% and 37.6%, respectively. The scale formation in the ovary and testis was approximately 2.0% for both sexes. The intersexuality was 42.2%, with the intersexuality among females being 49.5%, which was significantly higher than that of males (26.2%). Such findings indicate a negative impact on the reproductive output of the rock bream along the southern coast of Korea; however, a more detailed study is required to ascertain accurate causes.

Implementation and Effectiveness of Smart Equipment Engineering System (스마트 설비관리시스템 구축 및 효과분석)

  • Sim, Hyun-Sik
    • Journal of the Semiconductor & Display Technology
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    • v.16 no.3
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    • pp.121-126
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    • 2017
  • EES System support to maximize equipment efficiency by providing real-time information of main equipment which has a significant effect on product quality and productivity, and to prevent equipment failure by detecting equipment abnormality in advance. Smart Equipment Engineering System(S-EES) integrates the activities performed at equipment that are the core of production activities and manages them by system so as to maximize the efficiency of equipment and raise the quality level of products to one level. In other words, when the product is put into the equipment, the recipe is downloaded through the RMS, the recipe is set to the optimal condition through R2R(process control), and the system detects and controls the abnormality of the equipment during operation through the FDC function in real time it means. In this way, we are working with the suitable recipe that matches the lot of product, detecting the abnormality of the equipment during operation, preventing the product from being defective, and establishing a system to maximize the efficiency through real-time equipment management. In this study, we review the present status and problems of equipment management in actual production lines, collect the requirements of the manufacturing line for the PCB line, design and develop the system, The measurement model was studied.

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Spectrum of Pulmonary Fibrosis from Interstitial Lung Abnormality to Usual Interstitial Pneumonia: Importance of Identification and Quantification of Traction Bronchiectasis in Patient Management

  • Takuya Hino;Kyung Soo Lee;Joungho Han;Akinori Hata;Kousei Ishigami;Hiroto Hatabu
    • Korean Journal of Radiology
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    • v.22 no.5
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    • pp.811-828
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    • 2021
  • Following the introduction of a novel pathological concept of usual interstitial pneumonia (UIP) by Liebow and Carrington in 1969, diffuse interstitial pneumonia has evolved into UIP, nonspecific interstitial pneumonia (NSIP), and interstitial lung abnormality (ILA); the histopathological and CT findings of these conditions reflect the required multidisciplinary team approach, involving pulmonologists, radiologists, and pathologists, for their diagnosis and management. Concomitantly, traction bronchiectasis and bronchiolectasis have been recognized as the most persistent and important indices of the severity and prognosis of fibrotic lung diseases. The traction bronchiectasis index (TBI) can stratify the prognoses of patients with ILAs. In this review, the evolutionary concepts of UIP, NSIP, and ILAs are summarized in tables and figures, with a demonstration of the correlation between CT findings and pathologic evaluation. The CT-based UIP score is being proposed to facilitate a better understanding of the spectrum of pulmonary fibrosis, from ILAs to UIP, with emphasis on traction bronchiectasis/bronchiolectasis.

Assessment of Risk Factors for Dental Developmental Disorders in Pediatric Cancer Survivors

  • Jihyun Lee;Hyung-Jun Choi;Jaeho Lee;Je Seon Song;Chung-Min Kang
    • Journal of the korean academy of Pediatric Dentistry
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    • v.50 no.4
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    • pp.421-433
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    • 2023
  • This study was to examine the developmental dental abnormalities in childhood cancer survivors. Risk factors were assessed for 125 children with radiographic data through a retrospective analysis of medical records and panoramic images. 68.0% of childhood cancer survivors exhibited at least one dental abnormality. The types of abnormalities varied depending on the age at cancer diagnosis and treatment intensity, ranging from microdontia (43.2%), to abnormal root development (39.2%) and tooth agenesis (33.6%). Logistic regression analysis demonstrated that a young age at diagnosis (under 3 years), the use of heavy metal agents, a history of hematopoietic stem cell transplantation (HSCT), and combination treatment of chemotherapy, radiation therapy, and HSCT were associated with a significantly higher risk for overall dental abnormalities. The increased risk ratios were 6.00, 3.06, 3.22, and 7.87, respectively (p < 0.05). The results of this study will predict dental abnormality in permanent dentition according to the diagnosis age and treatment method of childhood cancer.

Effect of Age of Laying Hens and Grade of Egg Shell Abnormality on Internal Egg Quality (산란계 주령과 계란 난각 형태이상 정도가 내부품질에 미치는 영향)

  • Kim, Heui-Soo;Kim, Sun-Man;Noh, Jae-Jung;Lee, Jae-Ik;Lee, Hyun-Jung;Jo, Cheo-Run
    • Journal of Animal Science and Technology
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    • v.54 no.1
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    • pp.43-49
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    • 2012
  • This study was carried out to investigate the effects of age of laying hens and grade of shell abnormality on internal egg quality. At each week, 1,000 eggs were randomly selected from 21,000 eggs laid by Hy-Line hens (100,000 birds) aged from 56 to 62 wk. The samples were divided into normal and externally abnormal eggs by an official egg grader. Then, egg quality including egg weight, egg white height, Haugh unit and yolk color was evaluated from each normal and abnormal eggs. The production rate of externally normal and abnormal eggs was 81.22 and 18.78%, respectively. No difference found in the production rate by the increase of hen's age, but Haugh unit of eggs from hens of 60-wk-old was higher (p<0.05) than that of 56-wk-old. When the same age groups were compared, egg white height and Haugh unit were lower in eggs which were externally abnormal. When the grade of abnormality increased, egg white height and Haugh unit were decreased further (p<0.05). Among the externally abnormal eggs, malformation showed the lowest Haugh unit. In conclusion, the shell abnormality of eggs laid by hens aged 56 to 62 wk was closely related with internal egg quality. Therefore, the grading external egg quality in the present egg grading system is directly related with the internal egg freshness.