• Proceedings of the Korean Society of Applied Entomolohy Conference
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• 2001.11a
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• pp.145-145
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• 2001

• Proceedings of the Korean Society of Applied Entomolohy Conference
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• 2002.11a
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• pp.71-71
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• 2002

• Proceedings of the Korean Society of Applied Entomolohy Conference
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• 2001.11a
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• pp.125-125
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• 2001

• The Korean Journal of Soil Zoology
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• v.1 no.1
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• pp.62-67
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• 1996

• Parasites, Hosts and Diseases
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• v.40 no.2
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• pp.75-81
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• 2002

We investigated population densities of mosquitoes infected with sporozoites in three highly epidemic areas of Josan-ri and Jangpa-ri (Paju City) and Dongjung-ri (Yeoncheon County) in Korea. Anopheline mosquitoes were collected front both indoors and outdoors by human baiting collection method during the period of the first week of June to the second week of September 1999. Total 13,296 female mosquitoes were collected and 8,650 (65.1%) were Anophelines. Thirty seven percent (3,199) of the Anopheline mosquitoes were captured outdoors and 63.9% (5,531) indoors. Employing a sandwich enzyme-linked immunosorbent assay (ELISA), we analyzed a total of 7,820 Anopheline mosquitoes and found that 7 Anopheline mosquitoes were infected with sporozoites. The positive rate in Josan-ri was 0.14% (5/3,500) and 0.15% (2/1,370) in Jangpa-ri. The total positive rate in all three surveyed areas was 0.09% (7/7,820). The mosquitoes infected with the sporozoites were detected on June $28^{th}$ (n=2), July $5^{th}$ (n=1), July $19^{th}$ (n=1), August $9^{th}$ (n=1), September $6^{th}$ (n=1), and the last one on September $13^{th}$ (n=1). They were all classified as Anopheles sinensis, which showed positive reaction in ELISA test. Therefore it might be concluded that Anopheles sinensis plays an important role in re-emerging malaria transmission in Korea.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.11
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• pp.6739-6742
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• 2013

Background: Breast cancer is a major health problem worldwide. Olive oil induces apoptosis in some cancer cells due to phenolic compounds like oleuropein. Although oleuropein has anticancer activity, the underlying mechanisms of action remain unknown. The study aimed to assess the mechanism of oleuropin-induced breast cancer cell apoptosis. Materials and Methods: p53, Bcl-2 and Bax gene expression was evaluated by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) in luminal MCF-7 cells. Results: Oleuropein-induced apoptosis was accompanied by up-regulation of both p53 and Bax gene expression levels and down-regulation in Bcl2. Conclusions: Oleuropein induces apoptosis in breast tumour cells via a p53-dependent pathway mediated by Bax and Bcl2 genes. Therefore, oleuropein may have therapeutic potential in breast cancer patients by inducing apoptosis via activation of the p53 pathway.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4555-4559
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• 2012

Breast cancer causes death due to distant metastases in which tumor cells produce matrix metalloproteinase (MMP) enzymes which facilitate invasion. Oleuropein, the main olive oil polyphenol, has anti-proliferative effects. This study aimed to investigate the effect of oleuropein on the metastatic and anti-metastatic gene expression in the MDA human breast cancer cell line. We evaluated the MMPs and TIMPs gene expression by semi-quantitative reverse transcriptase polymerase chain reaction (RT-PCR) in treated and untreated cells. This study demonstrated that OL may induce anti-metastatic effects on human breast cancer cells. We found that TIMP1,-3, and -4 were over-expressed after all periods of incubation in treated cancer cells compared to untreated cells, while MMP2 and MMP9 genes were down-regulated, at least initially. Treatment of breast cancer cells with oleuropein could help in prevention of cancer metastasis by increasing the TIMPs and suppressing the MMPs gene expressions.

• Korean Journal of Plant Taxonomy
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• v.47 no.3
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• pp.171-179
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• 2017

Ten species of vascular plants newly recorded in Uzbekistan are presented. The first record of Anthemis ruthenica from the northern side of the Alay range is confirmed, and the species was found for the second time in a neighborhood of Tashkent as an alien. Carduus arabicus as a native plant in Central Asia is recorded for the first time from Western Pamir-Alay. Chondrilla brevirostris, C. macrocarpa, and C. phaeocephala are from the desert and adyrs zones. Crinitaria tatarica and Crepis mira collected from Western Tien-Shan are presented, Olgaea baldschuanica first recorded on the Babatag range of mountains as a subendemic species and Erigeron andryaloides from the Hissar range are reported here as among the flora of Uzbekistan. The former Centaurea apiculata Ledeb. was accepted as a synonym of C. scabiosa L. subsp. apiculata. All records were collected in different habitats of Uzbekistan. Taxonomic remarks, pictures and distribution maps for these species are provided.

• Asian-Australasian Journal of Animal Sciences
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• v.2 no.3
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• pp.289-291
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• 1989

• Proceedings of the Korean Society of Applied Entomolohy Conference
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• 2002.05a
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• pp.191-191
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• 2002