• Asian Pacific Journal of Cancer Prevention
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• v.14 no.2
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• pp.1077-1082
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• 2013

Background: Renal cell carcinoma (RCC) is a malignancy with a poor prognosis. We aimed to explore whether the expression of Long Non-Coding RNA (LncRNA) growth arrest-specific transcript 5 (GAS5) is associated with RCC genesis. Methods: We selected twelve clinical samples diagnosed for renal clear cell carcinoma and found that the LncRNA GAS5 transcript levels were significantly reduced relative to those in adjacent unaffected normal renal tissues. Results: In addition, expression of GAS5 was lower in the RCC cell line A498 than that in normal renal cell line HK-2. Furthermore, using functional expression cloning, we found that overexpression of GAS5 in A498 cells inhibited cell proliferation, induced cell apoptosis and arrested cell cycling. At the same time, the migration and invasion potential of A498 cells were inhibited compared to control groups. Conclusion: Our study provided the first evidence that a decrease in GAS5 expression is associated with RCC genesis and progression and overexpression of GAS5 can act as a tumor suppressor for RCC, providing a potential attractive therapeutic approach for this malignancy.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.11 no.5
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• pp.2701-2722
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• 2017

Key generation is essential for protecting wireless networks. Based on wireless channel reciprocity, transceivers can generate shared secret keys by measuring their communicating channels. However, due to non-simultaneous measurements, asymmetric noises and other interferences, channel measurements collected by different transceivers are highly correlated but not identical and thus might have some discrepancies. Further, these discrepancies might lead to mismatches of bit sequences after quantization. The referred mismatches significantly affect the efficiency of key generation. In this paper, an efficient key generation scheme leveraging wireless channel reciprocity is proposed. To reduce the bit mismatch rate and enhance the efficiency of key generation, the involved transceivers separately apply discrete cosine transform (DCT) and inverse discrete cosine transform (IDCT) to pre-process their measurements. Then, the outputs of IDCT are quantified and encoded to establish the bit sequence. With the implementations of information reconciliation and privacy amplification, the shared secret key can be generated. Several experiments in real environments are conducted to evaluate the proposed scheme. During each experiment, the shared key is established from the received signal strength (RSS) of heterogeneous devices. The results of experiments demonstrate that the proposed scheme can efficiently generate shared secret keys between transceivers.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.8
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• pp.3542-3566
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• 2018

In this paper, we investigate a buffer-aided wireless powered cooperative communication network (WPCCN), in which the source and relay harvest the energy from a dedicated power beacon via wireless energy transfer, then the source transmits the data to the destination through the relay. Both the source and relay are equipped with an energy buffer to store the harvested energy in the energy transfer stage. In addition, the relay is equipped with a data buffer and can temporarily store the received information. Considering the buffer-aided WPCCN, we propose two buffer-aided relaying protocols, which named as the buffer-aided harvest-then-transmit (HtT) protocol and the buffer-aided joint mode selection and power allocation (JMSPA) protocol, respectively. For the buffer-aided HtT protocol, the time-averaged achievable rate is obtained in closed form. For the buffer-aided JMSPA protocol, the optimal adaptive mode selection scheme and power allocation scheme, which jointly maximize the time-averaged throughput of system, are obtained by employing the Lyapunov optimization theory. Furthermore, we drive the theoretical bounds on the time-averaged achievable rate and time-averaged delay, then present the throughput-delay tradeoff achieved by the joint JMSPA protocol. Simulation results validate the throughput performance gain of the proposed buffer-aided relaying protocols and verify the theoretical analysis.

• Progress in Superconductivity and Cryogenics
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• v.18 no.2
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• pp.25-29
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• 2016

High charge state electron cyclotron resonance (ECR) ion source is important on the performance of heavy ion accelerators. In this paper, a low temperature superconductor (LTS) was used to make a hexapole coil for an 18-GHz ECR ion source. Several hexapole structures, including racetrack, graded racetrack, and saddle were implemented and analyzed for the hexapole-in-solenoid ECR ion source system. Under the appropriate radial confinement field, the smaller outer radius of hexapole can be better for the solenoid design. Saddle hexapole was selected by comparing the wire length, maximum outer radius of the hexapole, the Lorentz force at the end part of the hexapole and the maximum magnetic field in the coil. Based on saddle hexapole, a new design for hexapoles, the snake hexapole, was developed in this paper. By comparative analysis of the Lorentz force at the end part of the saddle and snake hexapoles, the snake hexapole is much better in the ECR ion source system. The suggested design for the ECR ion source with the snake hexapole is presented in this paper.

• Progress in Superconductivity and Cryogenics
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• v.18 no.2
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• pp.21-24
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• 2016

In recent years, the iron-dominated high-temperature superconductor (HTS) quadrupole magnets are being developed for heavy ion accelerators. Field analyses for iron-dominated quadrupole magnets were based on the normal-conducting (NC) quadrupole magnet early in the development for accelerators. Some conclusions are still in use today. However, the magnetic field of iron-dominated HTS quadrupole magnets cannot fully follow these conclusions. This study established an HTS quadrupole magnet model and an NC quadrupole magnet model, respectively. The harmonic characteristics of two magnets were analyzed and compared. According to the comparison, the conventional iron-dominated quadrupole magnets can be designed for maximum field gradient; the HTS quadrupole magnet, however, should be considered with varying field gradient. Finally, the HTS quadrupole magnet was designed for the changing field gradient. The field quality of the design was improved comparing with the result of the previous study. The new design for the HTS quadrupole magnet has been suggested.

• International Journal of Naval Architecture and Ocean Engineering
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• v.9 no.5
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• pp.473-483
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• 2017

Comprehensive consideration regarding influence mechanisms of initial imperfections on ultimate strength of spherical shells is taken to satisfy requirement of deep-sea structural design. The feasibility of innovative numerical procedure that combines welding simulation and non-linear buckling analysis is verified by a good agreement to experimental and theoretical results. Spherical shells with a series of wall thicknesses to radius ratios are studied. Residual stress and deformations from welding process are investigated separately. Variant influence mechanisms are discovered. Residual stress is demonstrated to be influential to stress field and buckling behavior but not to the ultimate strength. Deformations are proved to have a significant impact on ultimate strength. When central angles are less than critical value, concave magnitudes reduce ultimate strengths linearly. However, deformations with central angles above critical value are of much greater harm. Less imperfection susceptibility is found in spherical shells with larger wall thicknesses to radius ratios.

• International Journal of High-Rise Buildings
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• v.2 no.3
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• pp.171-178
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• 2013

The emergence of a growing number of tall buildings, often with unusual shapes and innovative structural systems, has led to the realization of the need for and the importance of field measurements. The new China Central Television (CCTV) Tower in Beijing is one of tall buildings with a highly unusual shape and a complex structural system, requiring field measurements to identify its dynamic characteristics for the subsequent dynamic analysis of the tower under wind excitation, seismic-induced ground motion and traffic-induced ground motion. The structural system and the finite element model of the CCTV Tower are first introduced in this paper. The computed natural frequencies and mode shapes are then presented as a reference for the field measurement. After introducing the arrangement of the ambient vibration measurement, the field measured natural frequencies and damping ratios of the CCTV Tower are presented and the measured natural frequencies are finally compared with the computed ones. It was found that the structural damping ratios of the CCTV Tower are small and the computed natural frequencies are smaller than the measured ones by about 12~17%.

• Journal of Magnetics
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• v.16 no.2
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• pp.104-107
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• 2011

In the present study, we systematically investigated the effect of mechanical milling on the magnetic properties of $Sm_2Fe_{17}N_x$ powders produced by the reduction-diffusion process. The Sm-Fe powders obtained by the reduction-diffusion process were composed of an $Sm_2Fe_{17}N_x$ single phase. After nitrogenation, the coercivity and saturation magnetization of the powders were 0.48 kOe and 13.32 kG, respectively. The particle size largely decreased down to less than $2\;{\mu}m$ in diameter after ball milling for 30 hours. However, there is no evidence that the $Sm_2Fe_{17}N_x$ was decomposed to Sm-N and ${\alpha}$-Fe even after ball milling for 30 hours. The coercivity was significantly improved up to 8.82 kOe after milling for 60 hours. However, the magnetization decreased linearly with the ball milling time.

• Journal of Power Electronics
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• v.16 no.3
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• pp.1087-1096
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• 2016

This paper reports an investigation conducted on two diagnostic methods based on the switching voltage pattern of IGBT open-circuit faults in voltage-source inverters (VSIs). One method was based on the bridge arm pole voltage, and the other was based on bridge arm line voltage. With an additional simple circuit, these two diagnostic methods detected and effectively identified single and multiple open-circuit faults of inverter IGBTs. A comparison of the times for the diagnosis and anti-interference features between these two methods is presented. The diagnostic time of both methods was less than 280ns in the best case. The diagnostic time for the method based on the bridge arm pole voltage was less than that of the method based on the bridge arm line voltage and was 1/2 of the fundamental period in the worst case. An experimental study was carried out to show the effectiveness of and the differences between these two methods.

• Wind and Structures
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• v.23 no.1
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• pp.45-57
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• 2016

Open-cross-section composite beam (OCB) tends to suffer vortex-induced vibration (VIV) due to its bluff aerodynamic shape. A cable-stayed bridge equipped with typical OCB is taken as an example in this paper to conduct sectional model wind tunnel test. Vortex-induced vibration is observed and maximum vibration amplitudes are obtained. CFD approach is employed to calculate the flow field around original cross sections in service stage and construction stage, as well as sections added with three different countermeasures: splitters, slabs and wind fairings. Results show that flow separate on the upstream edge and cause vortex shedding on original section. Splitters can only smooth the flow field on the upper surface, while slabs cannot smooth flow field on the upper or lower surface too much. Thus, splitters or slabs cannot serve as valid aerodynamic means. Wind tunnel test results show that VIV can only be mitigated when wind fairings are mounted, by which the flow field above and below the bridge deck are accelerated simultaneously.