• Steel and Composite Structures
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• 제24권5호
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• pp.561-568
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• 2017

Steel frames are widely used in steel structures. Exiting steel structures may be needed to strengthen for various reasons. Carbon Fiber Reinforced Polymers (CFRP) is one of the materials that are used to strengthen steel structures. Most studies on strengthening steel structures have been done on beams and steel columns. No independent study, to the researcher's knowledge, has studied the effect of CFRP strengthening on steel frames. This study explored the use of CFRP composite on retrofitting square hollow section (SHS) steel frames, using numerical investigations. Ten Finite Element (FE) models, which were strengthened with CFRP sheets, were analyzed under different coverage length, number of layers, and location of CFRP composite. One FE model without strengthening was analyzed as a control FE model to determine the increase of the ultimate load in the strengthened steel frames. ANSYS software was used to analyze the SHS steel frames. The results showed that the coverage length and the number of layers of CFRP composite have a significant effect on increasing the ultimate load of the SHS steel frames. The results also showed that the location of CFRP composite had no similar effect on increasing the ultimate load and the amount of mid span deflection of the SHS steel frames.

• Steel and Composite Structures
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• 제25권5호
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• pp.593-601
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• 2017

Carbon Fiber Reinforced Polymer (CFRP) is one of the materials used to strengthen steel structures. Most studies on strengthening steel structures have been done on steel beams and steel columns. No independent study, to the researcher's knowledge, has studied the effect of CFRP strengthening on steel beam-columns, and it seems that there is a lack of understanding on behavior of CFRP strengthening on steel beam-columns. However, this study explored the use of adhesively bonded CFRP flexible sheets on retrofitting square hollow section (SHS) steel beam-columns, using numerical investigations. Finite Element Method (FEM) was employed for modeling. To determine the ultimate load of SHS steel beam-columns, ten specimens, eight of which were strengthened with the different coverage length and with one and two CFRP layers, with two types of section (Type A and B) were analyzed. ANSYS was used to analyze the SHS steel beam-columns. The results showed that the CFRP composite had no similar effect on the slender and stocky SHS steel beam-columns. The results also showed that the coverage length, the number of layers, and the location of CFRP composites were effective in increasing the ultimate load of the SHS steel beam-columns.

• Steel and Composite Structures
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• 제23권1호
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• pp.87-94
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• 2017

Steel structures often require strengthening due to the increasing life loads, or repair caused by corrosion or fatigue cracking. Carbon Fiber Reinforced Polymers (CFRP) is one of the materials used to strengthen steel structures. Most studies on strengthening steel structures have been carried out on steel beams and steel columns under centric compression load. No independent article, to the author's knowledge, has studied the effect of CFRP strengthening on steel columns under eccentric compression load, and it seems that there is a lack of understanding on behavior of CFRP strengthening on steel columns under eccentric compression load. However, this study explored the use of adhesively bonded CFRP flexible sheets on retrofitting square hollow section (SHS) steel columns under the eccentric compression load, using numerical investigations. Finite Element Method (FEM) was employed for modeling. To determine ultimate load of SHS steel columns, eight specimens with two types of section (Type A and B), strengthened using CFRP sheets, were analyzed under different coverage lengths, the number of layers, and the location of CFRP composites. Two specimens were analyzed without strengthening (control) to determine the increasing rate of the ultimate load in strengthened steel columns. ANSYS was used to analyze the SHS steel columns. The results showed that the CFRP composite had no similar effect on the slender and stocky SHS steel columns. The results also showed that the coverage length, the number of layers, and the location of CFRP composites were effective in increasing the ultimate load of the SHS steel columns.

• Steel and Composite Structures
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• 제41권5호
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• pp.637-648
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• 2021

Nowadays, one of the practical, fast and easy ways to strengthen steel elements is the use of Carbon Fiber Reinforced Polymer (CFRP). Most previous research in the CFRP strengthening of steel members has carried out on straight steel members. The main difference between horizontal curved beams and straight beams under vertical load is the presence of torsional moment in the horizontal curved beams. In the other words, the horizontal curved beams are analyzed and designed for simultaneous internal forces included bending moment, torsional moment, and shear force. The horizontal curved steel beams are usually used in buildings, bridges, trusses, and others. This study explored the effect of the CFRP strengthening on the behavior of the horizontal curved square hollow section (SHS) steel beams. Four specimens were analyzed, one non-strengthened curved steel beam as a control column and three horizontal curved steel beams strengthened using CFRP sheets (under concentrated load and uniform distributed load). To analyze the horizontal curved steel beams, three dimensional (3D) modeling and nonlinear static analysis methods using ANSYS software were applied. The results indicated that application of CFRP sheets in some specific locations of the horizontal curved steel beams could increase the ultimate capacity of these beams, significantly. Also, the results indicated when the horizontal curved steel beams were under distributed load, the increase rate in the ultimate capacity was more than in the case when these beams were under concentrated load.

• The Korean Journal of Physiology and Pharmacology
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• 제15권6호
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• pp.327-332
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• 2011

It has been shown that some opium derivatives promote cell death via apoptosis. This study was designed to examine the influence of opium addiction on brain and liver cells apoptosis in male and female diabetic and non-diabetic Wistar rats. This experimental study was performed on normal, opium-addicted, diabetic and diabetic opium-addicted male and female rats. Apoptosis was evaluated by TUNEL and DNA fragmentation assays. Results of this study showed that apoptosis in opium-addicted and diabetic opium-addicted brain and liver cells were significantly higher than the both normal and diabetic rats. In addition, we found that apoptosis in brain cells of opium-addicted and diabetic opium-addicted male rats were significantly higher than opium-addicted and diabetic opium-addicted female, whereas apoptosis in liver cells of opium-addicted and diabetic opium-addicted female rats were significantly higher than opium-addicted and diabetic opium-addicted male. Overall, these results indicate that opium probably plays an important role in brain and liver cells apoptosis, therefore, leading neurotoxicity and hepatotoxicity. These findings also in away possibly means that male brain cells are more susceptible than female and interestingly liver of females are more sensitive than males in induction of apoptosis by opium.

• Asian Pacific Journal of Cancer Prevention
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• 제16권18호
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• pp.8215-8220
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• 2016

Background: The prevalence of non-squamous cell malignant tumors of the oral cavity has not been evaluated in Iran extensively. The aim of this study was to evaluate epidemiological aspects of the oral malignancies with non-squamous cell origin during a 43-year period in the Faculty of Dentistry, Mashhad University of Medical Sciences, Iran. Materials and Methods: In this retrospective study, the records of all patients referred to dental school of Mashhad university of medical sciences in northeast of Iran, during the period 1971-2013 were evaluated. All confirmed samples of oral non squamous cell malignant tumors were included in this study. Demographic information including age, gender and location of the lesions were extracted from patient's records. Data were analyzed using SPSS statistical soft ware, Chi-square and Fisher's exact tests. Results: Among 11,126 patients, 188 (1.68%) non squamous cell malignant tumors were found, with mean age of 39.9 years ranging from 2 to 92 years. The most common tumors were mucoepidermoid carcinoma (33 cases) and lymphoma (32 cases). Non squamous cell malignant tumors occurred almost equally in men (94 cases) and women (93 cases). Most (134 cases) of them were located peripherally with high frequency in salivary glands (89 cases) and 52 cases were centrally with high frequency in the mandible (38 cases). Conclusions: More findings in this survey were similar to those reported from other studies with differences in some cases; it may be due to variation in the sample size, geographic and racial differences in tumors.

• Asian Pacific Journal of Cancer Prevention
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• 제17권sup3호
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• pp.59-64
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• 2016

Breast cancer (BC) is the most common cancer in females (27% of the total) and the main cause of death (16%) due to cancer in women in developed and developing countries. Variations in its incidence rate among geographical areas are due to various contributing factors. Since there have been a lack of studies on this topic in our country, the present spatial analysis of breast cancer incidence in Iran in 2009 was conducted using data from the national cancer registry system. The reported incidences of the disease were standardized according to the World Health Organization population and the direct method. Then data was inserted into the GIS software and finally, using the Hot Spot Analysis (Geties-Ord Gi), high-risk areas were drawn. Provinces with incidences 1.96 SD higher or lower than the national average were considered as hot spots or cold spots, at the significance level of 0.05%. In 2009, a total of 7,582 cases of BC occurred in Iran. The annual incidence was 33.2 per hundred thousand people. Our study showed that the highest incidence of BC in women occurred in the central provinces of the country, Tehran, Isfahan, Yazd, Markazi and Fars. The results of hot spots analysis showed that the distribution of high-risk BC was focused in central parts of Iran, especially Isfahan province (p <0.01). The other provinces were not significantly different from the national average. The higher incidence in central provinces may be due to greater exposure to carcinogens in urban areas, a Western lifestyle and high prevalence of other risk factors. Further epidemiological studies about the etiology and early detection of BC are essential.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2041-2047
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• 2016

Background: Liver cancer (LC) is the sixth world most common cancer and the second leading cause of cancer death. Due to the importance and necessity of awareness about the incidence and mortality of diseases to perform prevention programs, this study focused on data for LC and its relationship with the human development index (HDI) and its components in Asia in 2012. Materials and Methods: This ecological study was based on GLOBOCAN data for Asian countries. We assessed correlations between standardized incidence rates (SIR) and standardized mortality rates (SMR) of LC with HDI and its components using of SPSS18. Results: A total of 582,420 incident cases and 557,097 deaths were recorded in Asian countries in 2012. The five with the highest SIR were Mongolia, Lao PDR, Vietnam, Republic of Korea and Thailand and those with the highest SMR were Mongolia, Lao PDR, Vietnam, Cambodia and Thailand. A negative relation was observed between HDI and LC for SIR of 0.049 (P=0.748) and for SMR of 0.07 (P=0.645), with life expectancy at birth a positive relation for SIR of 0.061 (P=0.687) and a negative relation for SMR of 0.079 (P=0.603), with the average years of education a negative relation fo SIR of 0.476 (p=0.952) and for SMR of 0.032 (P=0.832), and with the country income level per person a negative relation for SMI of 0.11 (p=0.465) and for SMR of 0.113 (P=0.455). Conclusions: The incidence of LC is more in less developed and developing countries but statistically significant correlations were not found between standardized incidence and mortality rates of LC, and HDI and its dimensions.

• Clinical and Experimental Pediatrics
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• 제64권7호
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• pp.341-346
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• 2021

Background: The results differ among published studies regarding exposure to meconium and the risk of developing autism spectrum disorders (ASDs). Purpose: The present study pooled all of the epidemiologic studies retrieved from broader databases on the association between meconium exposure and risk of developing ASD in children. Methods: The Web of Science, PubMed, Scopus, and Google Scholar databases were searched without language restrictions for articles published between their inception to February 20, 2020, using relevant keywords. The pooled odds ratios (ORs) and their 95% confidence intervals (CIs) were calculated as random-effect estimates of the associations among studies. A subgroup analysis was conducted to explore any potential sources of heterogeneity among studies. Results: The pooled estimate of OR reported a weakly significant association between meconium exposure and ASD development in children (OR, 1.13; 95% CI, 1.03-1.24). There was low heterogeneity among the articles reporting risk for ASD among children (I²=19.3%; P=0.259). The results of subgroup analysis based on meconium exposure showed a significant association between a meconium-stained neonate and ASD development (OR, 1.18; 95% CI, 1.11-1.24). Couclusion: Meconium exposure was weakly associated with an increased risk of ASD. However, more evidence based on large prospective cohort studies is required to provide conclusive evidence about whether meconium exposure is associated with an increased risk of ASD development.

• Structural Engineering and Mechanics
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• 제67권2호
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• pp.207-217
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• 2018

In past years, numerous problems have vexed engineers with regard to buckling, corrosion, bending, and overloading in damaged steel structures. This article sets out to investigate the possible effects of carbon fiber reinforced polymer (CFRP) and steel plates for retrofitting deficient steel square hollow section (SHS) columns. The effects of axial loading, stiffness, axial displacement, the position and shape of deficient region on the length of steel SHS columns, and slenderness ratio are examined through a detailed parametric study. A total of 14 specimens was tested for failure under axial compression in a laboratory and simulated using finite element (FE) analysis based on a numerical approach. The results indicate that the application of CFRP sheets and steel plates also caused a reduction in stress in the damaged region and prevented or retarded local deformation around the deficiency. The findings showed that a deficiency leads to reduced load-carrying capacity of steel SHS columns and the retrofitting method is responsible for the increase in the load-bearing capacity of the steel columns. Finally, this research showed that the CFRP performed better than steel plates in compensating the axial force caused by the cross-section reduction due to the problems associated with the use of steel plates, such as in welding, increased weight, thermal stress around the welding location, and the possibility of creating another deficiency by welding.