• Bulletin of the Korean Chemical Society
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• 제25권10호
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• pp.1555-1558
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• 2004

Prunioside A is a unique, highly oxidized monoterpene glycoside isolated from the methanol extract of Spiraea prunifolia var. Simpliciflora's root. The ester derivatives were synthesized from the hydrolyzed compounds of prunioside A by ${\beta}$-glucosidase. The derivatives showed suppressive effects on the generation of nitric oxide in murine machrophage-like RAW 264.7 cells stimulated by lipopolysaccharide and interferon- ${\gamma}$.

• 한국의사학회지
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• 제32권2호
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• pp.19-27
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• 2019

For the purpose of searching examination in the connection with clinical medicine and the basic theory of Korean Medicine, we comparatively studied on the physiological system of Hyun-Gok (1912~1987) and the Hyunsang system of Ji-San (1927~2000). The results are as follows. The metabolism of Yin and Yang is connected 'Gallbladder (膽)'-'Bladder (膀胱)' and Man (男), Woman (女), Old aged (老), Young child (小) style. Man and Woman are divided in the body form chacteristic not by the sex. 'Gallbladder (膽)'-'Bladder (膀胱)' style are divided in the body form chacteristic by the terms of Yin (陰) and Yang (陽). 'Gallbladder (膽)' style represents excessive Yang and deficient Yin, 'Bladder (膀胱)' style represents excessive Yin and deficient Yang. The four composition factor of the body is connected Material basis (精) type, Vital energy (氣) type, Mental faculties (神) type and Blood (血) type. In the diagnosis of body form on the Hyungsang Medicine, there are several types of body shape and categories of people. The Material basis (精) type, Vital energy (氣) type, Mental faculties (神) type and Blood (血) type are classified by the four composition factor of the body. The structural-mechanics organization of five Internal Organs (臟) is connected five Internal Organs (臟) types and the running-animal (走), bird (鳥), fish (魚), turtle (甲) types in the Hyunsang system. The five Internal Organs (臟) types are percived on the ears, eyes, nose, mouth and facial complexion. And the running-animal, bird, fish, turtle types are accorded to the individual personalities and the most-developed part in the body trunk by the Organ picture (藏象) theory. The six atmospheric influences (六氣) is connected the six Kyung types (六經形). The six Kyung types are regulated by the shape of eyes and nose representing for the relation of Vital energy (氣) and Blood (血). By the comparative study on the physiological system of Hyun-Gok and the Hyunsang system of Ji-San, we can search the connection with clinical medicine and the basic theory of Korean Medicine.

• Investigative Magnetic Resonance Imaging
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• 제13권2호
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• pp.117-126
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• 2009

목적: 수치해석적인 방법을 통해 핵자기공명 분광기법에서의 다중양자 필터를 디자인하는 방법을 소개하고 이를 뇌의 중요한 대사체인 myo-inositol의 생체 내 검출에 이용하였다. 대상 및 방법 : 이를 위해 우선적으로 myo-inositol의 분광학적 성질을 조사 한 후 다중양자 필터의 echo time, mixing time 그리고 세번째 $9^{\circ}$ 펄스의 flip angle과 offset frequency같은 시퀀스 파라미터들을 최적화 하였다. 최적화된 필터는 우선적으로 실험 팬텀에서 테스트 한 후 최종적으로 인간의 두뇌에서 그 성능을 검증하였다. 결과: 실험결과를 토대로, 본 연구에서 제안하는 다중양자 필터를 사용하여 신호의 순수도가 크게 개선된 타겟 대사체의 신호를 얻을 수 있음을 알 수 있다. 결론: 수치해석적인 방법을 통하여 핵자기공명 분광기법에서의 다중양자 필터를 디자인함으로써 특히, 복잡한 스핀계를 갖는 타겟대사체의 신호의 순수도를 크게 강화할 수 있다.

• Archives of Plastic Surgery
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• 제42권6호
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• pp.686-694
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• 2015

Background Rosa damascena, a type of herb, has been used for wound healing in Eastern folk medicine. The goal of this study was to evaluate the effectiveness of rose placenta from R. damascena in a full-thickness wound model in mice. Methods Sixty six-week-old C57BL/6N mice were used. Full-thickness wounds were made with an 8-mm diameter punch. Two wounds were made on each side of the back, and wounds were assigned randomly to the control and experimental groups. Rose placenta ($250{\mu}g$) was injected in the experimental group, and normal saline was injected in the control group. Wound sizes were measured with digital photography, and specimens were harvested. Immunohistochemical staining was performed to assess the expression of epidermal growth factor (EGF), vascular endothelial growth factor (VEGF), transforming growth factor-${\beta}1$ (TGF-${\beta}1$), and CD31. Vessel density was measured. Quantitative analysis using an enzyme-linked immunosorbent assay (ELISA) for EGF was performed. All evaluations were performed on postoperative days 0, 2, 4, 7, and 10. Statistical analyses were performed using the paired t-test. Results On days 4, 7, and 10, the wounds treated with rose placenta were significantly smaller. On day 2, VEGF and EGF expression increased in the experimental group. On days 7 and 10, TGF-${\beta}1$ expression decreased in the experimental group. On day 10, vessel density increased in the experimental group. The increase in EGF on day 2 was confirmed with ELISA. Conclusions Rose placenta was found to be associated with improved wound healing in a mouse full-thickness wound model via increased EGF release. Rose placenta may potentially be a novel drug candidate for enhancing wound healing.

• 센서학회지
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• 제29권5호
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• pp.336-341
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• 2020

The deflection and null balance methods are used for precision force measurement in the precision industry. Since both methods are based on deformation, the performance of the load cell mechanism is important. In this study, the design variables were obtained via the free body diagram of a lever-linked Roberval mechanism (combined with a flexible hinge link and a Roberval mechanism), and the design characteristics were analyzed according to the weight method. Based on the design characteristics, the optimal design was conducted according to the weight method and FEM was used to verify its reliability.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2003년도 추계학술발표회
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• pp.149-153
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• 2003

The hydrodynamic forces acting on the submerged plate are composed of diffraction and radiation forces. Thus we have carried out the extensive experiments and numerical simulations to make clear the characteristics of the diffraction and radiation forces on the submerged plate. These experimental results are compared with the numerical ones, and we discuss the effect of nonlinear on the hydrodynamic forces acting on the submerged plate. As a result, we get the conclusion that the submerged plate is useful for reducing the wave exciting forces on the structure behind the submerged plate.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2007년도 7th International Meeting on Information Display 제7권2호
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• pp.1482-1485
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• 2007

A three-dimensional (3D)-two-dimensional (2D) convertible display system using a plastic fiber array is proposed. The proposed system has an advantage of making use of a light source for 3D image from an arbitrary location. The optical efficiency of 3D images in the proposed system is enhanced compared with previous research.

• 한국철도학회:학술대회논문집
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• 한국철도학회 2003년도 추계학술대회 논문집(II)
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• pp.448-453
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• 2003

Most urban transit companies recognize the necessity of classification for facility management Classification for urban transit facility is necessary for standardization of maintenance management. The practical application. however. is not easy because of the absence of standardization of classification for urban transit facility and the difficulty in objectification of breakdown structure. This study suggests a proposal of classification for maintenance management in urban transit facility. This study defines standardization of classification as facility, work, maintenance and attribute to manage urban transit facility. And attribute classification consist of material, equipment and document. The suggested classification can be used as a useful maintenance management tool that enables evaluation of urban transit facility by standardization. The results of this study could be used as references for related urban transit companies.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2004년도 하계학술대회 논문집 A
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• pp.236-238
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• 2004

In recent years wind turbine technology has undergone the rapid development in response to the demands for increased use of renewable sources of energy. Using wind turbines for production of electrical energy requires reliable operation. The increased share of wind power in electrical system makes it necessary to have grid-friendly interfaces between the wind turbines and the grid in order to maintain power quality. Increasingly wind turbines are being connected into electricity distribution system. The grid-connected wind power stations have many impacts on power systems such as voltage variations, harmonics. The paper investigates the influences of grid-connected wind power generation system on substation bus voltage.

• 한국GIS학회:학술대회논문집
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• 한국GIS학회 2010년도 춘계학술대회
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• pp.279-280
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• 2010

지오이드는 수직 높이 체계의 기준으로 다양한 방법으로 측정 된 중력값을 이용하여 계산된다. 따라서 지오이드의 계산에 사용된 관측자료에 따라 지오이드 사이에 차이가 발생할 수 있으나 이에 대한 연구가 상대적으로 미흡한 실정이다. 그 이유는 GPS/Leveling 자료와 같은 검증자료가 충분치 않아 제한된 범위 내에서만 분석이 수행되어 왔기 때문이다. 본 연구에서는 GPS/Leveling 자료를 이용하여 계산된 기하지오이드를 기준으로 중력기반 지오이드를 비교 분석하였다.