• Title/Summary/Keyword: Young-onset

Search Result 1,101, Processing Time 0.033 seconds

A study of serum lipid level and relation between the serum lipid level and coronary aneurysm after kawasaki disease (가와사끼병에서 혈청 지질 대사의 변화 및 관상동맥류에 관한 연구)

  • Chung, Churl Young;Kim, Chang Keun
    • Pediatric Infection and Vaccine
    • /
    • v.2 no.2
    • /
    • pp.186-192
    • /
    • 1995
  • We measured plasma concentrations of high density lipoprotein, total cholesterol and triglycerides in 31 patients with history of kawasaki disease during acute stage and convalescence stage. High density lipoprotein cholesterol and total cholesterol concentrations were significantly lower(P<0.001) in samples taken within 11 days of the onset of illness($28.7{\pm}12.4mg/dl$ and $145.20{\pm}29.60mg/dl$) than in the second samples taken 1-2months after onset of disease($51.5{\pm}15.2mg/dl$ and $175.4{\pm}29.0mg/dl$). Change of triglycerides was not significant. There was no correlation between the serum cholesterol cencentration and coronary aneurysm and continued long term surveillance of much population is necessary to monitor lipid level and their relation to development of premature coronary atherosclerosis.

  • PDF

A Case of Adult Onset Glycogen Storage Myopathy (성인형 당원축적근육병 1예)

  • Shin, Jung Hwan;Kim, Dong Gun;Shin, Je Young;Park, Sung Hye;Lee, Kwang Woo
    • Annals of Clinical Neurophysiology
    • /
    • v.16 no.2
    • /
    • pp.81-85
    • /
    • 2014
  • Primary metabolic myopathy as a type of congenital myopathies was first described by McArdle in 1951. Glycogen storage disease is a disease caused by genetic mutations involved in glycogen synthesis, glycogenolysis or glycolysis. Several types of glycogen storage disease are known to cause metabolic myopathies. We report a case of adult onset metabolic myopathy with glycogen storage.

Effects of ${\beta}$-Conglycinin and Glycinin on Thermal Gelation and Gel Properties of Soy Protein

  • Kang, Il-Jun;Lee, Young-Sook
    • Food Science and Biotechnology
    • /
    • v.14 no.1
    • /
    • pp.11-15
    • /
    • 2005
  • Dynamic shear moduli of isolated soy protein solutions upon heating were measured to monitor gelation. Onsets of gelation coincide with onset temperatures of denaturation in glycinin and ${\beta}$-conglycinin solutions, whereas in isolated soy proteins, onset of gelation was above denaturation temperature of ${\beta}$-conglycinin with storage modulus increasing in two steps. The first increase in storage modulus of isolated soy proteins occurred at about $78.5^{\circ}C$, while the second increase started at about $93^{\circ}C$. Gel properties of soy protein gels having different proportions of glycinin and ${\beta}$-conglycinin were measured by compression-decompression test. ${\beta}$-conglycinin was responsible for gel elasticity. Glycinin significantly increased hardness, toughness, and fracturability of gels at high heating temperature near $100^{\circ}C$. Results reveal texture of soy protein gels can be controlled by regulating ratio of glycinin to ${\beta}$-conglycinin and heating temperature.

Motion and Force Estimation System of Human Fingers (손가락 동작과 힘 추정 시스템)

  • Lee, Dong-Chul;Choi, Young-Jin
    • Journal of Institute of Control, Robotics and Systems
    • /
    • v.17 no.10
    • /
    • pp.1014-1020
    • /
    • 2011
  • This presents a motion and force estimation system of human fingers by using an Electromyography (EMG) sensor module and a data glove system to be proposed in this paper. Both EMG sensor module and data glove system are developed in such a way to minimize the number of hardware filters in acquiring the signals as well as to reduce their sizes for the wearable. Since the onset of EMG precedes the onset of actual finger movement by dozens to hundreds milliseconds, we show that it is possible to predict the pattern of finger movement before actual movement by using the suggested system. Also, we are to suggest how to estimate the grasping force of hand based on the relationship between RMS taken EMG signal and the applied load. Finally we show the effectiveness of the suggested estimation system through several experiments.

The Study for Correlation Among Auditory Development and Language Development of Children with Hearing Impairment (청각장애 아동의 청능발달과 언어발달간의 상관관계 연구)

  • Park, Sang-Hee;Kwon, Young-Ju
    • Speech Sciences
    • /
    • v.10 no.4
    • /
    • pp.255-261
    • /
    • 2003
  • The purpose of this study was to investigate correlation of auditory development and language development of children with hearing impairment Eighteen subjects with severe or profound hearing loss participated in this study. They were 22-to 55-month-olds who had hearing parents with no additional disabling conditions. The test material was the Meaningful Auditory Integration Scale (MAIS) and MacArthur Communicative Development Inventory-Korea (MCDI-K). A Pearson Correlation Coefficient was determined through a statistical analysis. The results followed as; firstly there was a strong correlation between auditory development and receptive language development. Secondly, there was a strong correlation between receptive language development and expressive language development. Finally, there was a strong correlation between auditory development and education onset time. Therefore, auditory training is important method for auditory rehabilitation and education onset time is important variation for auditory development.

  • PDF

Paraplegia due to Spinal Cord Infarction After Lifting Heavy Objects

  • Lee, Sung-Ho;Kim, Sung-Bum;Choi, Seok-Geun;Lim, Young-Jin
    • Journal of Korean Neurosurgical Society
    • /
    • v.43 no.2
    • /
    • pp.114-116
    • /
    • 2008
  • Spinal cord infarction is uncommon and usually presents with sudden onset of motor and sensory disturbances. We report a case of a 64-year-old women without previous medical history, who presented with acute onset of paraplegia after lifting. However, radiologic examinations did not show any abnormal lesion in the spinal cord. And, cerebrospinal fluid studies also showed no remarkable findings. This case illustrates the cause of spontaneous paraplegia after lifting injury and we consider the presumptive cause of paraplegia as spinal cord infarction.

Thrombosed Fusiform Dilatation of Persistent Median Artery with Normal Median Nerve (정상 정중신경에서 혈전을 가진 잔류정중동맥의 예)

  • Park, Gi-Young;Kwon, Dong Rak;Kwon, Dae Gil;Jung, Won Bin
    • Clinical Pain
    • /
    • v.18 no.1
    • /
    • pp.40-43
    • /
    • 2019
  • Carpal tunnel syndrome can be produced by abnormal mass effect due to trauma, ganglion cysts, various soft tissue tumors, musculotendinous variants, and aberrant vascular structures. Persistent median artery is one of the causes of the carpal tunnel syndrome. Thrombosed persistent median artery usually accompanies the anomaly of the median nerve and causes a sudden onset of severe pain and paresthesia. In contrast to previous literature, we report the rare case of gradual onset and mild symptom of a 53-year-old man with a thrombosed persistent median artery but without anomaly of the median nerve and abnormal finding of electrophysiologic study.

Effects of Step Length Change on Kinetic Characteristics While Stepping Over an Obstacle From a Position of Quiet Stance in Young and Elderly Adults: A Preliminary Study

  • Kim, Hyeong-Dong
    • Physical Therapy Korea
    • /
    • v.14 no.4
    • /
    • pp.66-74
    • /
    • 2007
  • The aim of the present study was to investigate age-related differences in stepping behavior in response to sensory perturbations of postural balance. The participants for this study were 2 healthy elderly adults (mean age=76.0) and 2 younger adults (mean age=25.5). Subjects were asked to step over a 10 cm high obstacle at self-paced speed with the right limb to land on the primary target (normal step length) that is 10 cm in diameter. However, if, during movement, the light was illuminated, then the subject had to step on the secondary target (long step length). It was planned that the onset of the light would be prior to peak Fx of swing limb, between swing peak Fx and swing toe-off, and after swing toe-off. In the younger adults these secondary visual cues were provided at mean times of 240 ms (standard deviation (SD)=11), 402 ms (SD=13), and 476 ms (SD=88) following the movement onset. Corresponding mean times for the healthy elderly were 150 ms (SD=67), 352 ms (SD=39), and 562 ms (SD=115). Results showed great changes in both group and visual cue condition in Fx ground reaction forces and temporal events following the swing toe-off. Swing limb acceleration force (Fx) and stance peak Fx1 was much greater in the young adults compared to the older adults. Both young and older adults increased stance peak Fx2 in the visual cue condition compared to normal stepping. There was no difference in stance peak Fx2 between the visual cue conditions in both groups. Similarly, the time to stance peak Fx2 was much longer for the visual cue condition than for the normal stepping. It was not different between the visual cue conditions in the young adults, but in the elderly mid and late cue was much greater than early cue. In addition, time to stance peak Fx2 and swing and stance time were much longer in the older adults compared to the young adults for the visual cue conditions. These results suggest that unlike young adults, elderly adults did not flexibly modify their responses to unexpected changes in step length while stepping over obstacles.

  • PDF

Health-Illness Transition of Patients with Young-Onset Parkinson's Disease (젊은 나이에 발병한 파킨슨병 환자의 건강-질병 전환 경험 과정)

  • Kim, Sung Reul;Lee, Sook Ja
    • Journal of Korean Academy of Nursing
    • /
    • v.43 no.5
    • /
    • pp.636-648
    • /
    • 2013
  • Purpose: The purpose of this study was to explore the health-illness transition of patients with Young-Onset Parkinson's Disease (YOPD). Methods: From June to November 2011, 17 patients with YOPD who visited a neurologic clinic in a tertiary hospital participated in the study. Data were collected through in-depth interviews and analyzed using the grounded theory of Strauss and Corbin. Results: The core category of the participants' health-illness transition emerged as 'reshaping identity following uncontrollable changes'. The participants' health-illness transition process consisted of six phases in sequence: ego withdrawal, loss of role, frustration, change of thought, modification of life tract, and second life. Although most participants proceeded through the six phases chronologically, some returned to the frustration phase and then took up the remaining phases. Conclusion: The study results provide an in-depth understanding of health-illness transition experiences in the participants. These findings suggest a need to develop appropriate nursing intervention strategies according to the different phases in the health-illness transition of patients with YOPD.

A Case of Pituitary Abscess with Abnormal MRI Features - A Case Report - (비전형적 MRI 소견을 가진 뇌하수체농양 1례 - 증례보고 -)

  • Park, Sang Woo;Hwang, Sung Nam;Park, Seung Won;Kim, Young Baeg;Choi, Duck Young
    • Journal of Korean Neurosurgical Society
    • /
    • v.29 no.7
    • /
    • pp.945-948
    • /
    • 2000
  • A sixty-three year old woman presented with sudden onset of dystonic twitching of the extremities and repeatedly downgrading of consciousness in the midnight. She had no history of medical illness in the past but had been suffered from fatigue recently before the onset of the attack. At admission she was neurologically free including neuro-ophthalmologic examination. MRI showed a high signal T1WI mass in the sella protruding into the suprasellar cistern. Hormonal study revealed low value of T3, T4, LH and FSH. Under the impression of pituitary apoplexy she underwent operation via transcranial route. When the protruding diaphragma sellae was opened, milkish pus spilled out. The thick capsule was biopsied and pus was sent for the study. The results of Gram staining and culture were both negative but pathologic report of the specimen was high infiltration of lymphocytes with few polymorphs.

  • PDF