• Molecular & Cellular Toxicology
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• v.1 no.2
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• pp.130-136
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• 2005

The purpose of this study was to evaluate whether the interactions between maternal folate deficiency and methylenetetrahydrofolate reductase (MTHFR) polymorphism increase the risk of elevated maternal serum homocysteine, short gestation and reduced infant birthweight. Healthy pregnant (n = 170; 24-28 gestational weeks; 20-40 years old) women were analyzed for the MTHFR genotype and serum levels of folate and homocysteine, and were then followed for gestational age and infant birthweight. The mean infant birthweight was highest in mothers carrying MTHFR CC and with a normal folate range, and they were followed by mothers carrying MTHFR CT or TT and a normal range of folate or a folate deficiency. Birthweight was the lowest in mothers whose carrying MTHFR CC with folate deficiency. Using two way ANOVA, we found that folate level and the MTHFR polymorphism interacted to affect birth-weight of infants (p=0.05). Among those mothers carrying MTHFR CC, those with folate deficiency showed a 543 g reduction in infant birthweight compared with those with normal folate levels. However, infant birthweight was no different for mothers, those who with folate deficiency compared to those with normal range of folate among mothers carrying the MTHFR CT or TT genotypes. This study suggests an interaction between maternal serum folate and the MTHFR polymorphisms of the mother on the risk of delivering reduced birthweight offspring. Folate supplementation of folate deficient pregnant women with the MTHFR wild type is suggested to reduce the risk of low birthweight.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.33 no.1
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• pp.16-23
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• 2022

Objectives: Early detection of developmental issues in infants and necessary intervention are important. To identify the comorbid conditions, a comprehensive evaluation is required. The study's objectives were to 1) generate scale items by identifying and eliciting concepts relevant to young children (12-71 months) with developmental delays, 2) develop a comprehensive screening tool for developmental delay and comorbid conditions, and 3) assess the tool's validity and cut-off. Methods: Multidisciplinary experts devised the "Infant Comprehensive Evaluation for Neurodevelopmental Delay (ICEND)," an assessment method that comes in two versions depending on the age of the child: 12-36 months and 37-71 months, through monthly seminars and focused group interviews. The ICEND is composed of three parts: risk factors, resilience factors, and clinical scales. In parts 1 and 2, there were 41 caretakers responded to the questionnaires. Part 3 involved clinicians evaluating ten subscales using 98 and 114 questionnaires for younger and older versions, respectively. The Child Behavior Checklist, Strengths and Difficulties Questionnaire, Infant-Toddler Social Emotional Assessment, and Korean Developmental Screening Test for Infants and Children were employed to analyze concurrent validity with the ICEND. The analyses were performed on both typical and high-risk infants to identify concurrent validity, reliability, and cut-off scores. Results: A total of 296 people participated in the study, with 57 of them being high-risk (19.2%). The Cronbach's alpha was positive (0.533-0.928). In the majority of domains, the ICEND demonstrated a fair discriminatory ability, with a sensitivity of 0.5-0.7 and specificity 0.7-0.9. Conclusion: The ICEND is reliable and valid, indicating its potential as an auxiliary tool for assessing neurodevelopmental delay and comorbid conditions in children aged 12-36 months and 37-71 months.

• Proceedings of the Korean Society of Life Science Conference
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• 2007.10a
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• pp.56.1-56.1
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• 2007

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• Clinical and Experimental Pediatrics
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• v.59 no.sup1
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• pp.80-83
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• 2016

Isolated anomalous right coronary artery originating from the pulmonary artery (ARCAPA) is a rare congenital coronary anomaly that is asymptomatic and discovered incidentally in most cases. ARCAPA is generally not considered a fatal defect in infancy or childhood, although cases of sudden death have been reported. Here, we report a 2-month-old female infant who presented with a prolonged fever that was determined to be caused by rhinovirus infection. Myocardial ischemia of the left ventricular posterior wall was already seen on echocardiography, and ARCAPA was discovered incidentally. The patient underwent successful surgical reimplantation of the right coronary artery to the aortic root to re-establish dual ostial circulation.

• Korean Journal of Childcare and Education
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• v.11 no.1
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• pp.63-82
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• 2015

The purpose of this study is to analyze the influence of the working-environment and job-satisfaction on the turnover intention of infant-care teachers. For this study, a survey was conducted on 200 infant-care teachers, who work in facilities of Northern Gyeonggi-do. The main results of this study are as follows: First, the turnover intention of infant-care teachers has no statistically significant differences by socio-demographic factors. Second, turnover intentions relate negatively to working-environment and job-satisfaction. More job-autonomy reduces the turnover intention and more job-conflict and job-burden increases the turnover intention. Third, the working-environment and job-satisfaction have influences on the turnover intention of infant-care teachers in the regression model. In conclusion, we need to improve the working-environment and to enhance job-satisfaction in order to reduce the turnover rate of infant-care teachers.

• The Journal of the Convergence on Culture Technology
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• v.3 no.4
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• pp.59-66
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• 2017

These days, IoT attached diaper are available in markets. It measures child's temperature, oxygen rate, or even humidity of diaper and send the result directly to parent's smartphone. This research emphasize the followings, due to the fact that use of IoT in context of infant care should ultimately be leaded to infant's wellbeing and healthy development. First, there can be many problems when you only focus on usability without careful consideration of the accuracy of the infant's health information produced by the IoT. Second, infant's needs and nature of child should be reflected when developing IoT which supports infant care. The use of the IoT should not take away the chance of physical contact such as eye-contact or patting and hugging between the caregiver and baby. IoT is very important, however in terms of infant development, connect with IoT cannot antecede contact with child.

• Korean Journal of Human Ecology
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• v.21 no.1
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• pp.59-70
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• 2012

The purposes of this study was to investigate the relationship and interaction between infant temperament, development, mother's parenting stress and social support on mother's self-efficacy. Participants in this study included 1610 infants (825 boys, 785 girls) and their mothers. The major findings of this study were as follows: First, infant temperament demonstrated a direct relationship to mother's self-efficacy. Lower levels of infant temperament indicated lower levels of self-efficacy, and higher levels of infant temperament indicated higher levels of self-efficacy. Second, infant development demonstrated a direct relationship to mother's self-efficacy. Greater communicative and social interaction between mother and child demonstrated a higher level of maternal self-efficacy. Third, mothers' parenting stress demonstrated a direct relationship to mother's self-efficacy. Higher levels of parenting stress demonstrated lower levels of maternal self-efficacy. Forth, Social support demonstrated a direct relationship to mother's self-efficacy. Greater levels of social support demonstrated lower level of maternal self-efficacy. Fifth, the greatest single relationship effecting mother's self-efficacy was mother's parenting stress. This research suggests the need for development of diverse social policies and programs to help mothers reduce maternal parenting stress and support the development of positive parenting skills with the goal of boosting mother's self-efficacy.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.15 no.2
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• pp.105-110
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• 2012

Gastric ulcers are rare in children and are typically seen in cases of Helicobacter pylori (H. pylori) infection, non-steroidal anti-inflammatory drugs (NSAIDs) use, and critical illnesses such as sepsis. The risk of a bleeding ulcer due to use of NSAIDs is dependent on the dose, duration, and the individual NSAIDs, but the bleeding may occur soon after the initiation of NSAID therapy. An experience is described of a 16-month-old infant with a bleeding gastric ulcer after taking the usual dosage of ibuprofen for 3 days. The infant was also successfully treated with endoscopic hemostasis. Even a small amount of ibuprofen may be associated with bleeding gastric ulcers in infant.

• Journal of the Korea Fashion and Costume Design Association
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• v.13 no.3
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• pp.31-43
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• 2011

This study investigates the differences in the purchasing behavior of infant & children's wear with the features of children and consumers. This study conducted a survey on female buyers of infant & children's wear. 558 questionnaires were analyzed by using SPSS 18.0 statistic program with factor analysis, Cronbach's ${\alpha}$, cluster analysis, ANOVA, and paired t-test. The results are as follows: 1. The buyer's value was identified with 3 factors: mental achievement value, social achievement value, and pleasure value. Three types of group by values were identified: group seeking mental social achievement, group seeking social achievement, and group seeking pleasure. 2. Fashion and conformity, pleasure pursuit, and reasonable price pursuit orientations showed significant differences among the value groups. 3. A significant difference was found in the imitation of wearing role models according to sibling relationships.

• Journal of Korean Society for Quality Management
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• v.34 no.2
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• pp.48-67
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• 2006

In this study, an investigation was done into service qualify factors of infant education Institutes, after which a positive verification was made in the relation of cause and effect between service quality, service value and customer satisfaction. Based on this verification, strategies were presented for plans to improve the service quality of infant education. In addition, identification was made into factors that affect customer satisfaction, re-registration intention and recommendation to others in putting forward service operational strategies for infant education institutes and making a comparative analysis on kindergartens and daycare centers.