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Effects of Bisphenol A on Dams during Lactation Period in Rats

  • Kim, Pan-Gyi;Leu, Jae-Hong;Kang, Hee-Joo;Kim, Jeong-Hyun
    • Proceedings of the Korean Environmental Health Society Conference
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    • 2003.06a
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    • pp.171-173
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    • 2003
  • Bisphenol A (4,4'-isopropylidenediphenol, C$\_$15/H$\_$16/O$_2$) is the monomer used in the manufacture of polycarbonate. Polycarbonate, in turn, is used in a wide array of plastic products, with new applications continuously being developed. Also it has been used to produce epoxy resins and polycarbonate plastics for food container. This study was carried out to investigate the effects of bisphenol A on lactation period to dams and F1, Sprague-Dawley females were mated with on 2:1 ratio basis. Various doses of bisphenol A (0, 2, 20, 200, and 2,000 $\mu\textrm{g}$/kg) were daily administered to females for 21 days after parturition. Dams and offsprings were sacrificed at the time of weaning. The results were as follows, 2000 $\mu\textrm{g}$/kg of bisphenol A decreased the dams' body weight at post-partum 18 days and also 200 and 2000 $\mu\textrm{g}$/kg of bisphenol A decreased the body weight of neonates at the days of post-partum 21 days. Bisphenol A increased the relative weights of liver and spleen in male offsprings, depending on the doses. But female offsprings showed high relative organ weights of ovaries, and low relative organ weights of uterine in a some dose-response manners. High dose of bisphenol A induced low viability of neonates exposed during lactation period. The dams treated with bisphenol A showed prematured estrous stage. Bisphenol A was recovered about 21.2% average in serum of dams, and also in offsprings'. The results indicate that the bisphenol A induces estrous cycle during lactation period in dams, also reaches to the of offspring through breast milk. Thus bisphenol A exopsed to dams and neonates via lactation induces some estrogenic and toxic effects.

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Biomechanical Analysis of Take-Off Techniques of Women's High Jump Winners at IAAF World Championships, Daegu 2011 (세계일류여자높이뛰기선수의 발구름 기술에 대한 바이오메카닉스적 분석)

  • Bae, Young-Sang;Kim, Eui-Hwan;KIm, Ki-Man;Lee, Jeong-Min;Kim, Sung-Sup;Kwon, Moon-Seok;Wi, Ung-Ryang
    • Korean Journal of Applied Biomechanics
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    • v.21 no.5
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    • pp.585-593
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    • 2011
  • The purpose of this study was to analyze, from a kinematical point of view, the high jump techniques of three women's high jump winners at the IAAF World Championships, Daegu 2011. The trends for the techniques of the world's top high jumpers were examined, with a view toward adapting these techniques to the physical characteristics of Korean women's high jumpers. It was valuable that Di Martino, who was the shortest in height, was able to win a medal by using a single arm swing take-off technique, along with a half flexed leading leg swing to attain a deep arch and clear the bar. This showed that the world's top athletes used jumping techniques with no decrease in the run-up velocity at the take-off. Furthermore, It appeared that the knee joint angle at take-off had a direct effect on the body position at take-off (H1).

Biomechanical Analysis of Men's High Jump Medalists in IAAF World Championships, Daegu 2011 (2011 대구세계육상선수권대회 남자 높이뛰기 메달리스트들의 바이오메카닉스적 특성 분석)

  • Kim, Eui-Hwan;Bae, Young-Sang;Kim, Sung-Sup;Kwon, Moon-Seok;Wi, Ung-Ryang;KIm, Ki-Man;Lee, Jeong-Min
    • Korean Journal of Applied Biomechanics
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    • v.21 no.5
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    • pp.573-584
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    • 2011
  • The purpose of this study was to perform a kinematic analysis of the high jump techniques of the three men's medalists at the 2011 IAAF Championships in Daegu (August 27-September 4, 2011). In particular, a three-dimensional coordinates method was used to analyze the last three strides before touchdown, the touchdown techniques, and the movements after takeoff toward the bar. An analysis of the, data for the biomechanical characteristics of the world's best high jumpers could contribute to an improvement in the performance of a national high jumper. The first conclusion of the data analysis was that the arm movements of the gold medalist, J. Williams, had a single arm form, whereas the arm movements of the other medalists were a double arm form. Second, the difference in the knee joint angles upon touchdown and toe-off was $10^{\circ}$. Third, J. Williams achieved his maximum CM height after takeoff (1.26 m) using the maximum flexion of his knee joint. Fourth, the foot contact duration of A. Dmitrik (0.11 s) was the shortest among the medalists, and the ratio for his transformation of horizontal velocity to vertical velocity was the greatest (75.25%) among the three. Last, the maximum CM height of T. Barry was the greatest, and his foot contact duration was the longest.

Changes in Urinary MDA and 8-OHdG Concentrations due to Wearing Personal Protective Equipment and Performing Protective Behaviors among Agricultural Workers in Korea (우리나라 일부 농업 종사자의 개인보호구 착용, 작업위생행위에 따른 소변 중 MDA, 8-OHdG 농도 변화)

  • Lee, Jiyun;Ji, Kyunghee;Kim, Bokyung;Park, Seokhwan;Kim, Pan-Gyi
    • Journal of Environmental Health Sciences
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    • v.43 no.6
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    • pp.467-477
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    • 2017
  • Objectives: Oxidative stress and DNA damage have been proposed as mechanisms linking pesticide exposure to health effects such as cancer and neurological diseases. We investigated whether protective measures could significantly reduce the levels of biomarkers for oxidative stress and DNA damage in agricultural workers. Methods: In the present study, the levels of malondialdehyde (MDA) and 8-hydroxy-2'-deoxyguanosine (8-OHdG), biomarkers related to oxidative stress and DNA damage, respectively, were analyzed in urine samples collected from agricultural workers in two provinces of Korea (n=60). The influence of wearing personal protective equipment (PPE) and performing protective behaviors on the levels of these two biomarkers was also evaluated. Results: The median urinary levels of MDA and 8-OHdG were 10.45 nmol/mg creatinine and 14.42 ng/mg creatinine in subjects living in region A, while they were 6.25 nmol/mg creatinine and 24.77 ng/mg creatinine in subjects living in region B, respectively. The levels of MDA and 8-OHdG were higher in male farmers. Farmers wearing greater numbers of PPE and performing more protective behaviors had significantly lower levels of MDA. Greater numbers of protective behaviors was significantly associated with lower levels of 8-OHdG. Conclusion: The results of the present study indicate that pesticide exposure could induce oxidative stress and DNA damage in agricultural workers, and that protective measures are important for mitigating pesticide exposure.

A Study on the Growth and Spatial Differentiation of Housing Market in Yongin City (용인시 주택시장의 성장과 공간적 분화에 관한 연구)

  • Joo, Kyung-Sik;Park, Young-Woo
    • Journal of the Korean Geographical Society
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    • v.45 no.2
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    • pp.240-255
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    • 2010
  • This empirical study researched the three major phenomena of differentiation of housing market under the large scale of new town construction in the metropolitan area, the spatial differentiation pattern of housing market due to the urban growth, and the relationship with the distribution of housing submarket and suburbanization. Yongin City, one of the most active growth cities among the metropolitan areas, is optimal place to investigate the spatial differentiation pattern of the housing submarket on the microscopic scale. Furthermore, Yongin City has not only the geographical benefit but also the strong influences from institutional, social, and environmental changes. This city is divided into four housing submarkets, where to Gangnam and Boondang, Gyeongbu and Youngdong expressway has significant effects. In addition, the housing tenure and size, household structure, educational background and income levels and so on also resulted in the differentiation of the housing submarket.

Comparative Analysis of Biomechanic Variables between Backlift and Leglift Type (BACKLIFT와 LEGLIFT의 들기 유형에 따른 역학적 변인 비교분석)

  • Kim, Eui-Hwan;Kim, Tae-Whan;Kim, Sung-Sup;Chung, Chea-Wook
    • Korean Journal of Applied Biomechanics
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    • v.17 no.4
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    • pp.209-219
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    • 2007
  • The purpose of this study was to analyze biomechanical mechanism (posture, moment of back joint, EMG) when athletes (Judo, Ssirum) and lay people lifted a load according to two different lift methods; backlift and leglift. The number of subjects was 12; 8 athletes (4 for Judo, 4 for Ssirum) and 4 lay people. We recorded a lift motion in backlift and leglift using 7 real time infrared cameras (vicon) and analyzed EMG pattern of major muscles for a lift (lattisimus dorsi, erector spinae, biceps femoris). In a backlift Judo players showed a biggest range of back flexion and extension motion and lay people flexed more than other groups at phase 2 in which an interaction between groups and events was statistically significant (p=.024). In a leglift Ssirum players more flexed their back in a barbell lift and there was a statistical significance (p=.021) between groups and events. For moment of back joints, 1) in a backlift a larger loading on back joints in all three groups at phase 2 when lifting down a barbell, 2) in a leglift a larger loading on back joints when lifting down a barbell in two athlete groups but a larger loading when lifting up a barbell in lay people group, and all groups did not show any statistical significance. For EMG, right lattisimus dorsi muscle in a backlift was statistical significant (p=.006) in an interaction between groups and phase but left lattisimus dorsi muscle was insignicant, and there was not any significance in a leglift. Generally atheletes (Judo and Ssirum) used more their muscles of lower extremity in lifting up and down and lay people did more their ones of upper extremity.

Antioxidative Activities and Quality Characteristics of Gruel as a Home Meal Replacement with Angelica keiskei Powder Pre-treated by Various Drying Methods (전처리 건조 방법에 따른 간편가정식용 신선초죽의 항산화 효과와 품질 특성)

  • Kim, Hae Young;Choi, Su-Jin;Ra, Ha-Na;Lee, Jong-Eun
    • Journal of the Korean Society of Food Culture
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    • v.29 no.1
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    • pp.91-100
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    • 2014
  • This study investigated the antioxidative activities and quality characteristics of gruel as a home meal replacement with Angelica keiskei powder pre-treated by far-infrared radiation or freeze-drying methods. Far-infrared treated Angelica keiskei powder (F-IAP) showed significantly lighter, weaker green, and stronger yellow color values than powder subjected to freezedrying (FAP) (p<0.001). F-IAP showed higher total phenolic compound contents than that of the FAP. ABTS radical scavenging activity of F-IAP was 50.31%, which was significantly higher than that of FAP, at 43.51% (p<0.05). Color values of gruel significantly decreased with increased addition of Angelica keiskei powder (p<0.05). Gruels containing far-infrared treated Angelica keiskei powder (F-IAG) showed higher total phenolic compound contents as well as ABTS radical scavenging activities compared to the gruels containing freeze-dried Angelica keiskei powder (FAG). Gruels containing 5 g of Angelica keiskei powder showed 2.0 to 2.5 times higher antioxidant activities than those containing powder alone due to the presence of other ingredients with antioxidant activities such as black soybean or sweet pumpkin. In the results of sensory evaluation, F-IAG containing more than 5 g of Angelica keiskei powder had higher sweetness and roasted grain flavor, as well as lower bitterness and astringency compared to FAG. Sensory acceptance tests of all samples showed higher scores than 5.0 representing possibilities of successful development of gruels as a home meal replacement containing Angelica keiskei powder.

Design and Implementation of Safe Commuting Management Mobile App for Preschoolers (학령전 아동 안전 통학 관리를 위한 모바일 앱 설계 및 구현)

  • Song, Doo heon;Park, Eui-In;Lee, Sang Joon;Lee, Junhyung
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.10a
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    • pp.434-436
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    • 2018
  • Accidents of commuting vehicles for preschoolers continue to occur despite various safety policies from the government. In order to minimize such accidents, it is necessary to use both the vehicle-mounted safety commutation management software for the driver, and the mobile App to manage the safe schooling of the children that can inform such information to parents in time. In this paper, we describe the design and implementation of the safety management software architecture. The mobile application is designed for Android operating systems. It informs current driving information if the bus as well as the list of current boarded children. Teacher in the bus can manage exceptional cases such as riding child without RFID and unregistered temporary riders like grandparent for convenience and flexibility.

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The Effects of Maitland Thoracic Mobilization Method on Cervical Alignment and Muscle Activity in Adult with Forward Head Posture

  • Kim, Dajeong;An, Hojung;Kim, Nyeonjun;Kim, Ayeon;Hong, Geurin;Kim, Soonhee
    • Journal of International Academy of Physical Therapy Research
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    • v.11 no.3
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    • pp.2119-2125
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    • 2020
  • Background: Adults with forward head posture (FHP) often suffer from thoracic hyperkyphosis and thoracic dysfunction, and including reduction of the craniovertebral angle (CV angle) and tightening of the superficial neck muscles. In order to treat thoracic dysfunction, interventions aimed at improving thoracic mobility are necessary. Objectives: To examine the effects of maitland manual mobilization therapy on the thoracic spine in adults with FHP. Design: Single-blind randomized controlled trial. Methods: Thirty adults with FHP who met the selection criteria were randomized to the thoracic multiple joint mobilization (TMJM; n=15) group and the thoracic general joint mobilization (TGJM; n=15) group. Joint mobilizations were performed for 23 minutes a day for 4 weeks continuously, two times per week. Outcome measures were ImageJ, BTS FREE EMG 1000, neck disability Index (NDI). Results: Although changes in the left sternocleidomastoid muscle activity and NDI scores over time between the two groups differed, other variables were noted only changes observed over time. Muscle activity in the right sternocleidomastoid increased again in the TGJM group post-intervention and 2 weeks after the end of the experiment, but changes in other variables were retained or improved, confirming the lasting effects of thoracic joint mobilization. Conclusion: Thoracic multiple joint mobilization may be recommended as a more effective intervention for adults with FHP.

Quality Characteristics of Cookies with Various levels of Functional Rice Flour (기능성 쌀 쿠키의 품질 특성 연구)

  • L.Kim, Hye-Young;Lee, In-Seon;Kang, Ji-Yoon;Kim, Gee-Yeoun
    • Korean Journal of Food Science and Technology
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    • v.34 no.4
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    • pp.642-646
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    • 2002
  • Pysicochemical and sensory characteristics of cookies with various levels of functional rice flour were investigated in this study. Dough pH of 10% substituted group and Spreadability of 20 and 30% substituted group had significantly higher values than that of control group. Density of Dough had significantly the largest value of 1.27 with 10% substituted sample group. The L value of brightness in control group had significantly the largest value of 69.31. The b value of 20% substituted sample group had significantly the largest value of 35.60. Results of sensory characteristics showed significantly higher savory aroma, savory flavor, hardness and brownness with 10% substituted sample group. Acceptance test of cookies with 20% substituted sample group showed higher overall acceptability than those of others. Quality caracteristics of 10 to 30% subsituted sample groups indicated significantly similar or higher values compared to those of control showing the possibilities of developments in health concerned funtional rice coopkies.