• Asian Spine Journal
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• v.12 no.6
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• pp.1127-1145
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• 2018

Several theories have been proposed to explain the etiology of adolescent idiopathic scoliosis (AIS) until present. However, limited data are available regarding the impact of vitamin D insufficiency or deficiency on scoliosis. Previous studies have shown that vitamin D deficiency and insufficiency are prevalent in adolescents, including AIS patients. A series of studies conducted in Hong Kong have shown that as many as 30% of these patients have osteopenia. The 25-hydroxyvitamin D3 level has been found to positively correlate with bone mineral density (BMD) in healthy adolescents and negatively with Cobb angle in AIS patients; therefore, vitamin D deficiency is believed to play a role in AIS pathogenesis. This study attempts to review the relevant literature on AIS etiology to examine the association of vitamin D and various current theories. Our review suggested that vitamin D deficiency is associated with several current etiological theories of AIS. We postulate that vitamin D deficiency and/or insufficiency affects AIS development by its effect on the regulation of fibrosis, postural control, and BMD. Subclinical deficiency of vitamin K2, a fat-soluble vitamin, is also prevalent in adolescents; therefore, it is possible that the high prevalence of vitamin D deficiency is related to decreased fat intake. Further studies are required to elucidate the possible role of vitamin D in the pathogenesis and clinical management of AIS.

• Bulletin of the Korean Mathematical Society
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• v.55 no.2
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• pp.431-448
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• 2018

This paper is concerned with the positive definite solutions of the nonlinear matrix equation $X-A^*{\bar{X}}^{-1}A=Q$, where A, Q are given complex matrices with Q positive definite. We show that such a matrix equation always has a unique positive definite solution and if A is nonsingular, it also has a unique negative definite solution. Moreover, based on Sherman-Morrison-Woodbury formula, we derive elegant relationships between solutions of $X-A^*{\bar{X}}^{-1}A=I$ and the well-studied standard nonlinear matrix equation $Y+B^*Y^{-1}B=Q$, where B, Q are uniquely determined by A. Then several effective numerical algorithms for the unique positive definite solution of $X-A^*{\bar{X}}^{-1}A=Q$ with linear or quadratic convergence rate such as inverse-free fixed-point iteration, structure-preserving doubling algorithm, Newton algorithm are proposed. Numerical examples are presented to illustrate the effectiveness of all the theoretical results and the behavior of the considered algorithms.

• Bulletin of the Korean Chemical Society
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• v.34 no.10
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• pp.3039-3045
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• 2013

Dual-frequency ultrasound assisted photocatalysis (DUAP) method was proposed to degrade a stable organic model effluent, cresol red (CR), using the prepared $Fe^{3+}$-doped $TiO_2$ with active carbon fiber loading ($Fe^{3+}-TiO_2/ACF$) as photocatalyst. The influence of key factors, including Fe doping amount and power density of dual-frequency ultrasounds (20/40 kHz), on the degradation efficiency was investigated. The degradation efficiency rises to 98.7% in 60 min accompanied by the color removal of CR liquid samples from yellow to colorless transparent at optimal conditions. A synergy index of 1.40 was yielded by comparison with single ultrasound assisted photocatalysis (SUAP) and the photocatalysis without ultrasound assisted (UV/$TiO_2$), indicating that a clear synergistic effect exists for the DUAP process. Obvious enhancement of degradation efficiency for the DUAP process should be attributed to production of large amount of free radicals by strong cavitational effects of dual ultrasounds.

• Korean Journal of Agricultural Science
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• v.46 no.3
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• pp.417-426
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• 2019

This study was conducted to evaluate seasonal effects on production performance of lactation sows reared in two different environments in South Korea. A total of 76 sows ($Landrace{\times}Yorkshire$) from the Dankook University experimental farm and 120 sows ($Landrace{\times}Yorkshire$) from a commercial farm were collected. In the current study, reduced (p < 0.01) feed intake and energy intake during lactation were observed in warm season compared with cool season in both farms. Sows in cool season had higher backfat thickness at weaning but lower back fat loss (p < 0.01) than those in warm season. The weaning to estrus interval was lower (p < 0.01) in cool season than in warm season. Piglets weaned in warm season had lower (p < 0.01) body weight (BW), body weight gain (BWG), and average daily gain (ADG) at weaning than did those weaned in cool season on the Dankook University farm, whereas the reduction effect was only observed during 0 - 21 d on the commercial farm (p < 0.01). Moreover, piglets weaned in cool season had higher BW, BWG, and ADG (p < 0.05) on both farms. In conclusion, our results indicate that warm season had very negative effects on feed intake and production performance of lactating sows and piglets.

• Journal of Korean Medical classics
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• v.10
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• pp.591-617
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• 1997

In the field of the theory about constitution(體質), the theory of 'Yun Qi(運氣) has close relations hip with the formation of theory of constitution. It is seen in the chapter 'Osangjungdae-ron("五常政大論")' that the theory of influenced the theory of constitution and talent by the 'Concept of Evaporation(氣化)'. In the chapter 'Yin-Yang twenty five men types' of the book the 'Ling Shu("靈樞")' the twenty five constitution types by the theory of 'Yan Qi is stated. And in the book 'Nei Ching("內經")' the constitution types of five elements' motion is described. In the theory of the 'five elements' motion and six kinds of natural factors' had such a problem that the individuals having the same born year and Qi had the same prescriptions irrespective of each other's constitution. So for the resolution of this problem the constitution theory of 'Yun Qi' had been formed by the mediation of the 'MyengRiHak(命理學)' and the theory of 'Yun Qi' in the book the 'OUnYukKiHanYeHakBoGam("五運六氣韓醫學寶鑑")'. But following problems should be resolved in chrono-inedieine. Those are the difference of men who has born in some year-day-time, each 'Yun Qi's brea king point, local time, summer time, living circumstances, twins, the concept of 'Zhung Won(中元)', etc.

• Journal of Acupuncture Research
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• v.19 no.1
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• pp.203-209
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• 2002

Objective : The chonguinyoung pulse diagnosis method is convenient than twelve meridian pulse diagnosis method The $\ll$Maek-bup(脉法)$\gg$ are founded at Mawangtweo(馬王堆) of the han dynasty tomb in 1973, but it could diagnosis the exsitance of illness of twelve meridian also . Methods : In accordance to $\ll$Naekuoung(內經)$\gg$ inyoungmaek(人迎脈) in could be taken at the which is the pulse point of carotid artery on the line of foot yangmyoung stomach meridian (足陽明胃經) and chongumaek (寸口脈) at the taeyoun acu-point (太淵穴) pulse point on the line of hand taeyeun lung meridian (手太陰肺經). Results : Chonguinyoung pulse diagnosis method could be emphased on the point of diagnosing sick person and healthy person by the balance of yin (陰) yan (陽) composition in the body. Conclusion : Chonguinyoung pulse diagnosis method could be the indication of improvement and progress of disease also it could be adapt to diagnosis of twelve meridian and it is impossible to making choice of acupuncture, medication, moxibustion, vene-section and strengthing-eleminating treatment method (補瀉方法).

• Asian-Australasian Journal of Animal Sciences
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• v.27 no.9
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• pp.1355-1359
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• 2014

To detect goat vascular endothelial growth factor (VEGF)-mediated regrowth of hair, full-length VEGF164 cDNA was cloned from Inner Mongolia cashmere goat (Capra hircus) into the pET-his prokaryotic expression vector, and the recombinant plasmid was transferred into E. coli BL21 cells. The expression of recombinant $6{\times}his-gVEGF164$ protein was induced by 0.5 mM isopropyl thio-${\beta}$-D-galactoside at $32^{\circ}C$. Recombinant goat VEGF164 (rgVEGF164) was purified and identified by western blot using monoclonal anti-his and anti-VEGF antibodies. The rgVEGF164 was smeared onto the dorsal area of a shaved mouse, and we noted that hair regrowth in this area was faster than in the control group. Thus, rgVEGF164 increases hair growth in mice.

• Structural Engineering and Mechanics
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• v.88 no.4
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• pp.379-387
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• 2023

Wind and earthquake loads may cause strong vibrations in large-span cable-stayed bridges, leading to the inability of the bridge to operate normally. An improved Pounding Tuned Mass Damper (PTMD) system was designed to improve the safety of the large-span cable-stayed bridge. The vibration control effect of the improved PTMD system on the large-span cablestayed bridge under the combined action of earthquake-wind-traffic was studied. Furthermore, the impact of different parameters on the vibration suppression performance of the improved PTMD system was analyzed. The numerical results indicate that the PTMD system is very effective in suppressing the displacements of the bridge caused by both the traffic-wind coupling and traffic-earthquake coupling. Moreover, the number, mass ratio, pounding stiffness, and gap values have a significant influence on the vibration suppression performance of the improved PTMD system. When the number of PTMD is increased from 3 to 9, the vibration reduction ratio of the vertical displacement is increased from 25.39% to 48.05%. As the mass ratio changes from 0.5% to 2%, the vibration reduction ratio increases significantly from 22.23% to 53.30%.

• Journal of the Daesoon Academy of Sciences
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• v.25_1
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• pp.1-22
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• 2015

This paper took Jeonkyeong (典經) of Daesunjinrihoe(大巡眞理會) as the basic text and studied how Kangjeungsan(姜甑山), the Sangje (上帝), had embraced Chinese myth in process of formation of his religious thought focusing on Yan Emperor(炎帝) Shennong(神農) myth and Shanrangang(禪讓) myth (namely Danchu myth). First when we examine the myth surrounding Kangjeungsan's birth, it deeply emraced a feeling-birth myth(感生神話), we could realize that this is a universe motif through myth of hero birth in East Asia. Further judging from the analysis of geographic space of Kangjeungsan's activity, it included a variety of mythical and Daoist related place names. I think this is because of the fact that birth place of Kangjeungsan and the surrounding area is the locality of Xian(仙) tradition where major characters of Danhak sect(丹學派) have been turned out, and that Korean way of Xian suppressed by the regulatory system has been widely rooted in the public. Especially it's interesting that Jeungsan, the pen name of Kangjeungsan, ambiguously connotes Siru mountain(甑山), a place of his training, and the spiritual realm of the 『Zhouyicantongqi(周易參同契)』. Then I examined the God of fire Shennong myth which has been actively admitted and embraced by Kangjeungsan. Kangjeungsan put the root of his pedigree on Shennong and there is a close affinity between Shennong and Dongyi(東夷) such as Buyeo(夫餘), Goguryeo(高句麗), etc. These Dongyi spirits are losers against the Chinese major myth and beings of ressentiment. At the same time the predecessor of Jiutianyingyuanleishengpuhuatianzun(九天應元雷聲普化天尊) who shares mythical characteristics with the God of fire Shennong was a formerly Taishi(太師) Wenzhong(聞仲) of Yin(殷) dynasty. He was defeated and died by Zhou(周) dynasty, and was deified. The fact that Kangjeungsan regarded himself as a descendent of Shennong and possessed divinity of Jiutianyingyuanleishengpuhuatianzun connotes that he represents all beings of ressentiment such as family of Yin and Dongyi. However, Kangjeungsan set a religious milestone by turning revenge for such ressentiment at tribe level into religious sublimation. At the end Shanrang myth which has been critically embraced by Kangjeungsan was reviewed. According to the existing Shanrang myth, Danchu(丹朱) was unworthy and not succeeded in the succession to the throne. Then good natured Emperor Shun(舜) succeeded to the throne from Emperor Yao(堯). However, the reality of Shanrang myth was a violent change of sovereign power and Danchu was a victim in the process of such violent change. Kangjeungsan shrewdly grasped the reality of ancient China and cast light on presence of Danchu. And he emphasized the need of religious sublimation of revenge, Haewon(解冤). His such awareness of culture had a close relation with revisionist standpoint of independent Danhak sect expressing a skeptical glance at systematic, commensurate and authentic historical view of Chinese civilization. And further Kangjeungsan cosmologically and causationally reinterpreted revenge of Danchu. He established a universal salvation theology which has a corresponsive connotation in regard to embracement of Shennong myth. In conclusion, embracement of Chinese myth by Kangjeungsan was a creative work of reinterpretation resulting in an inherent religious connotation through a process of appropriation, that is independent and selective introjection.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.11
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• pp.5339-5343
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• 2012

The induction of apoptosis in target cells is a key mechanism for most anti-tumor therapies. Bufalin is a cardiotonic steroid that has the potential to induce differentiation and apoptosis of tumor cells. Research on bufalin has so far mainly involved leukemia, prostate cancer, gastric cancer and liver cancer, and has been confined to in vitro studies. The bufadienolides bufalin and cinobufagin have been shown to induce apoptosis in a wide spectrum of cancer cell. The present article reviews the anticancer effects of bufalin. It induces apoptosis of lung cancer cells via the PI3K/Akt pathway and also suppressed the proliferation of human non-small cell lung cancer A549 cell line in a time and dose dependent manner. Bufalin, bufotalin and gamabufotalin, key bufadienolides, significantly sensitize human breast cancer cells with differing ER-alpha status to apoptosis induction by the TNF-related apoptosis-inducing ligand (TRAIL). In addition, bufadienolides induce prostate cancer cell apoptosis more significantly than that in breast epithelial cell lines. Similar effects have been observed with hepatocellular carcinoma (HCC) but the detailed molecular mechanisms of inducing apoptosis in this case are still unclear. Bufalin exerts profound effects on leukemia therapy in vitro. Results of multiple studies indicate that bufalin has marked anti-tumor activities through its ability to induce apoptosis. Large-scale randomized, double-blind, placebo or positive drug parallel controlled studies are now required to confirm the efficacy and apoptosis-inducing potential of bufalin in various cancers in the cliniucal setting.