• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
• /
• v.11 no.2
• /
• pp.68-81
• /
• 2006

As one of the on-going projects to investigate the biogeochemical characteristics of tidal flat, we develop seasonal mass balance calculations (or DIP, DIN and DON in Gomso Bay. We have obtained 13-hours time-series data of salinity, tidal current, nutrients, and chlorophyll-a of seawater for spring, dry summer, rainy summer and winter during $1999{\sim}2000$. DIP of $-1.10{\times}10^6g\;P\;day^{-1},\;-4.50{\times}10^5g\;P\;day^{-1}$ was out-fluxed from the bay to the bay proper for spring and dry summer, respectively. Whereas $1.06{\times}10^4g\;P\;day^{-1}$ of net influx of DIP was found during winter and $2.72{\times}10^6g\;P\;day^{-1}$ of net influx was also found during the rainy summer. Therefore we suggest the role of Gomso tidal flat as a source of DIP fur the seasons of spring and summer, but as an opposite role during the rainy summer and winter but much smaller in magnitude. Except winter, the advection process by tidal current is found the most dominant flux among the diverse fluxes of DIP in the bay. Whereas ground water is estimated as the strongest flux of TDN except winter. TDN of $1.38{\times}10^7g\;N\;day^{-1},\;2.45{\times}10^6g\;N\;day^{-1},\;and\;4.65{\times}10^7g\;N\;day^{-1}$ was in-fluxed to the bay from the bay proper far spring, rainy summer and summer, respectively. Only $-1.70{\times}10^7g\;N\;day^{-1}$ of net out-flux was found during the winter. Therefore we suggest the role of Gomso tidal flat as a sink of TDN far the year round except winter.

• Economic and Environmental Geology
• /
• v.57 no.2
• /
• pp.233-241
• /
• 2024

This study was conducted to investigate the geological distribution characteristics of fluorine in rocks, which can be a major resource of forest aggregates in Korea. Samples of forest aggregates were collected from 224 sites in 22 cities and counties for this study. The national background concentration was 344 mg/kg, which was significantly lower than the average fluorine concentration of crustal, which was 625 mg/kg, and slightly higher than the average fluorine concentration of world soil, which was 321 mg/kg. In terms of region and tectonic structure, fluorine concentrations were investigated to be highest in Gyeonggi-do(394 mg/kg) and Gyeonggi massif(396 mg/kg), respectively. The concentration distribution by the origin of the parent rock was in the order of metamorphic rock(362 mg/kg) > sedimentary rock(354 mg/kg) > igneous rock(328 mg/kg), and the concentration distribution by geologic ages was the highest in the Paleozoic at 394 mg/kg. The concentration distribution by rock types was in the order of diorite(515 mg/kg) > gneisses(377 mg/kg) > schists(344 mg/kg) > phyllite(306 mg/kg) > granites(305 mg/kg) > quartz porphyry(298 mg/kg). Consequently, it is speculated that gneisses and schists, Precambrian metamorphic rocks in the Gyeonggi massif that forms the crust of Gyeonggi-do, contain high fluorine concentrations.

• Journal of Wetlands Research
• /
• v.26 no.1
• /
• pp.21-31
• /
• 2024

Macromia daimoji Okumura, 1949 was designated as an endangered species and also categorized as Class II Endangered wildlife on the International Union for Conservation of Nature (IUCN) Red List in Korea. The spatial distribution of this species ranged within a region delimited by northern latitude from Sacheon-si(35.1°) to Yeoncheon-gun(38.0°) and eastern longitude from Yeoncheon-gun(126.8°) to Yangsan-si(128.9°). They generally prefer microhabitats such as slowly flowing littoral zones of streams, alluvial stream islands and temporarily formed puddles in the sand-based lowland streams. The objectives of this study were to analyze the similarity of benthic macroinvertebrate communities in M. daimoji habitats, to predict the current potential distribution patterns as well as the changes of distribution ranges under global climate change circumstances. Data was collected both from the Global Biodiversity Information Facility (GBIF) and by field surveys from April 2009 to September 2022. We adopted MaxEnt model to predict the current and future potential distribution for M. daimoji using downloaded 19 variables from the WorldClim database. The differences of benthic macroinvertebrate assemblages in the mainstream of Nakdonggang were smaller than those in its tributaries and the other streams, based on the surrounding environments and stream sizes. MaxEnt model presented that potential distribution displayed high inhabiting probability in Nakdonggang and its tributaries. Applying to the future scenarios by Intergovernmental Panel on Climate Change (IPCC), SSP1 scenario was predicted to expand in a wide area and SSP5 scenario in a narrow area, comparing with current potential distribution. M. daimoji is not only directly threatened by physical disturbances (e.g. river development activities) but also vulnerable to rapidly changing climate circumstances. Therefore, it is necessary to monitor the habitat environments and establish conservation strategies for preserving population of M. daimoji.

• Journal of the Korean Society of Radiology
• /
• v.18 no.1
• /
• pp.45-52
• /
• 2024

In this study, an AI-based algorithm was developed to prevent image quality deterioration and reading errors due to patient movement in PET/CT examinations that use radioisotopes in medical institutions to test cancer and other diseases. Using the Mothion Free software developed using, we checked the degree of correction of movement due to breathing, evaluated its usefulness, and conducted a study for clinical application. The experimental method was to use an RPM Phantom to inject the radioisotope 18F-FDG into a vacuum vial and a sphere of a NEMA IEC body Phantom of different sizes, and to produce images by directing the movement of the radioisotope into a moving lesion during respiration. The vacuum vial had different degrees of movement at different positions, and the spheres of the NEMA IEC body Phantom of different sizes produced different sizes of lesions. Through the acquired images, the lesion volume, maximum SUV, and average SUV were each measured to quantitatively evaluate the degree of motion correction by Motion Free. The average SUV of vacuum vial A, with a large degree of movement, was reduced by 23.36 %, and the error rate of vacuum vial B, with a small degree of movement, was reduced by 29.3 %. The average SUV error rate at the sphere 37mm and 22mm of the NEMA IEC body Phantom was reduced by 29.3 % and 26.51 %, respectively. The average error rate of the four measurements from which the error rate was calculated decreased by 30.03 %, indicating a more accurate average SUV value. In this study, only two-dimensional movements could be produced, so in order to obtain more accurate data, a Phantom that can embody the actual breathing movement of the human body was used, and if the diversity of the range of movement was configured, a more accurate evaluation of usability could be made.

• BMB Reports
• /
• v.57 no.2
• /
• pp.110-115
• /
• 2024

Alterations in DNA methylation play an important pathophysiological role in the development and progression of colorectal cancer. We comprehensively profiled DNA methylation alterations in 165 Korean patients with colorectal cancer (CRC), and conducted an in-depth investigation of cancer-specific methylation patterns. Our analysis of the tumor samples revealed a significant presence of hypomethylated probes, primarily within the gene body regions; few hypermethylated sites were observed, which were mostly enriched in promoter-like and CpG island regions. The CpG Island Methylator Phenotype-High (CIMP-H) exhibited notable enrichment of microsatellite instability-high (MSI-H). Additionally, our findings indicated a significant correlation between methylation of the MLH1 gene and MSI-H status. Furthermore, we found that the CIMP-H had a higher tendency to affect the right-side of the colon tissues and was slightly more prevalent among older patients. Through our methylome profile analysis, we successfully verified the methylation patterns and clinical characteristics of Korean patients with CRC. This valuable dataset lays a strong foundation for exploring novel molecular insights and potential therapeutic targets for the treatment of CRC.

• Journal of the Korea Organic Resources Recycling Association
• /
• v.31 no.4
• /
• pp.13-28
• /
• 2023

This study assessed the biochemical methane potential (B_u-P) of three grass species-Poa pratensis (PP), Zoysia japonica (ZJ), and Agrostis stolonifera (AS). B_u-P values were determined as 0.330 Nm³/kg-VS_added for PP, 0.297 Nm³/kg-VS_added for ZJ, and 0.261 Nm³/kg-VS_added for AS. Notably, PP exhibited superior suitability for methane production. The investigation also examined the impact of silage storage duration on PP grass clippings, revealing a 19% decline in B_u-P from an initial value of 0.269 Nm³/kg-VS_added on day 0 to 0.217 Nm³/kg-VS_added on day 180. Throughout the storage period, there were significant increases in neutral detergent fiber (NDF), acid detergent fiber (ADF), and crude protein (CP) contents, rising from 67.59%, 39.68%, and 3.02% on day 0 to 77.12%, 54.65%, and 6.24% on day 180, respectively. These findings highlight the influence of storage duration on the anaerobic digestibility of PP grass clippings. To effectively utilize grass clippings as a renewable resource for methane production, further studies considering factors such as initial moisture content, pretreatment methods, and potential effects of residual pesticides are necessary to optimize anaerobic digestion efficiency for herbaceous biomass.

• Korean Chemical Engineering Research
• /
• v.62 no.1
• /
• pp.87-98
• /
• 2024

This study was conducted to investigate the efficiency of the filtering sets composed of fiberboards, which were fabricated with lignocellulosic fiber and cork oak bark-based activated carbon (COA), as well as traditional Korean paper handmade from mulberry trees (KP) for the filtration of PM, TVOC and HCHO. Three-layers fiberboards (WRF) were fabricated with wood fiber in its surface layers and recycled fiber/COA in its core layer using a protein-based adhesive with the resin content of 8%. Filtering sets were composed of three WRF and one sheet of KP. Concentrations of PM, TVOC and HCHO generated with the combustion of a incense in a sealed laboratory hood were reduced efficiently with the operation of air-purifier installed the filtering sets. Except for the WRF fabricated with 4%/4% resin contents, other WRF were prepared with 5%/3% and 6%/2% resin contents in surface/core layers, and then the WRF were used with KP for the fabrication of filtering sets. Filtration efficiency of the filtering sets was improved as the core-layer resin content applied in the fabrication of WRF decreased. In addition, filtration efficiency of the WRF-based filtering set fabricated with KP of 25 g/m² basis weight was higher than that with KP of 45 g/m² basis weight. Filtering sets composed of three-layers fiberboards (RWF) that recycled fiber and wood fiber/COA were used in its surface and core layers, respectively, and KP-25g showed higher filtration efficiency than those of WRF-based filtering sets. Air-inhalation equipment installed the RWF-based, WRF-based filtering sets and without filtering set were operated in small indoor and large outdoor spaces. Efficiency for filtering PM and TVOC of the RWF-based filtering sets was higher than that of other filtering sets. It is concluded that fiberboard-based filtering sets composed of RWF and KP-25g can be used as a filter for reducing the concentrations of PM and TVOC existed in indoor and outdoor spaces.

• Journal of Technology Innovation
• /
• v.31 no.3
• /
• pp.39-73
• /
• 2023

The field of Management of Technology(MOT) emerged in response to the need for research management within U.S. public research institutions during the 1960s. Since its inception, it has proliferated significantly, being practiced in more than 809 institutions globally and over 19 institutions in Korea, encompassing both research and educational endeavors. Particularly noteworthy is the substantial investment of government resources, primarily channeled through the Ministry of Industry since 2007, which has expeditiously established a comprehensive framework for cultivating graduate-level MOT expertise, marked by both quantitative and qualitative advancements. The educational curriculum in the realm of Korean MOT deviates from foreign counterparts through distinctive pathways, exemplified by its emphasis on industry practice-oriented educational programs, standardization and isomorphism across different schools, as well as its interconnectedness with proximate academic disciplines. This research systematically undertakes an analysis of the curriculum in Korean MOT graduate schools, thereby ascertaining its intrinsic identity and distinct attributes. In this endeavor, a comprehensive examination of eleven principal MOT textbooks(three in Korean and eight in English) is conducted to delineate the primary content of the curriculum across seven thematic domains. Moreover, the study deliberates on its differentiation from neighboring academic disciplines and the definitional attributes of MOT. Subsequently, this analysis also encompasses nine Korean MOT graduate programs, projecting the seven thematic domains onto their respective curricula. The findings illuminate that within the context of Korean graduate programs, a substantial proportion of the curriculum, amounting to 62.5%, is dedicated to facets encompassing the operational aspects of technology management within corporate contexts, technology management specific to varying industries and technologies, and collaborative endeavors between academia and industry in the form of projects and seminars. Evidently, the Korean approach to technology management education is notably geared towards the cultivation of adept practitioners capable of executing technology management functions at a mid-tier managerial level, aligned with the exigencies of regional industries. Grounded in the analysis of technology management curricula, this study extrapolates implications for the future trajectory of MOT education in Korea, encompassing a consideration of the stages of industrial development. It underscores the necessity to augment the educational curricula pertaining conceptual foundation of technology and innovation, strategic perspectives of technology and innovation, and the socio-economic context of technology management.

• Journal of Life Science
• /
• v.34 no.7
• /
• pp.476-484
• /
• 2024

Although two-dimensional (2D) monolayer cell culture models are still widely used as the optimal models for anticancer activity research, three-dimensional (3D) multicellular tumor spheroid (3D MTS) models that can better approximate the tumor environment can offer an alternative to bridge the gap between in vitro and animal model studies. Isoalantolactone is among the sesquiterpene lactones found in medicinal plants, including the roots of Elecampane (Inula helenium L.), and is known to have various pharmacological activities, including anticancer activity. In this study, we investigated whether the anticancer activity of isoalantolactone observed in 2D models could be reproduced in a 3D MTS model derived from human hepatocellular carcinoma (HCC) Hep3B cells. According to our results, isoalantolactone inhibited the formation of MTSs in a manner dependent on the treatment concentration, which was accompanied by an increase in reactive oxygen species (ROS) generation. In particular, as isoalantolactone treatment and the culture time increased, the area of proliferating cells was replaced by cells in which apoptosis was induced. Additionally, in MTSs, isoalantolactone increased the expression of death-receptor-related proteins and the activity of caspase-3, and it decreased the expression of the Bax/Bcl-2 expression ratio and total poly(ADP-ribose) polymerase. However, when the production of ROS was artificially blocked, all these changes caused by isoalantolactone were attenuated and the cell survival rate of MTS cells was restored. Therefore, the results of this study suggest that the induction of apoptosis in Hep3B cell-derived MTSs by isoalantolactone is achieved through the activation of extrinsic and intrinsic pathways and is ROS-dependent.

• Food Science and Preservation
• /
• v.31 no.2
• /
• pp.267-275
• /
• 2024

Artemisia fukudo Makino belongs to the Asteraceae family, is a halophyte that can grow in salinity soils and is known for its various physiological activities. However, few studies were comparing it according to the growth environment. Therefore, in this study, we analyzed the antioxidant activity, functional ingredients, and safety of Artemisia fukudo Makino according to the growth environment. Total polyphenol content was the highest in native mature leaves, but 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and 1,1-diphenyl-2-picrylhydrazyl radical scavenging activity was higher in cultivated leaves than in native leaves. The total mineral content, excluding sodium, was higher in cultivated than in native leaves. The content of potassium and calcium was higher in cultivated leaves than in native leaves. In addition, heavy metal analysis showed that cultivated leaves were generally lower than those of native leaves. Residual pesticides were not detected in all samples. In conclusion, since there is no significant difference in cultivated leaves compared to native leaves, it was judged that cultivated leaves could be used as a variety to be grown and mass-produced.