• The Korea Journal of Herbology
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• v.24 no.4
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• pp.127-135
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• 2009

Objectives : Gagam-Gongjin-dan (GGD) composited with Cervi parvum Cornu, Corni Fructus, Angelica gigantis Radix, Lycii Fructus, Dioscoreae Rhizoma, Citri Pericarpium, Gastrodiae Rihzoma, Agastachis Herba, Cassiae cortkex, Scutellariae Radix, Schisandrae Fructus has been traditionally used for chronic diseases or weakness after illness in oriental countries. However, little is known about the effects of methanol extract of GGD on immune responses to ovalbumin (OVA) plus alum. Therefore, the purpose of this study was to investigate the effects of GGD on immune responses to ovalbumin plus alum in Balb/c mice. Methods : In this study, the extract of GGD was prepared by extracting with methanol for 7 days. The extract was freeze-dried following filtration through vacuum distillation system. Mice were orally administrated with or without GGD extract of different doses (50-200 mg/kg/day) for 30 days. We examined the effects of GGD extract on the serum levels of total IgE, OVA-specific IgE, IgG1, IgG2a, and CTACK/CCL27 production and CCR10 expression in lymph node cells and body weight change and foot pad swelling responses in ovalbumin treated Balb/c. Results : The oral administration of GGD dose-dependently reduced the serum levels of total IgE, OVA-specific immunoglobulin (IgE, IgG1 and IgG2b) and CTACK/CCL27 production in ovalbumin treated BALB/c mice. The levels of CCR10 expression from lymph node cells of OVA treated mice were markedly suppressed by treatment with GGD in a concentration dependent manner. Furthermore, foot pad swelling responses were also markedly suppressed by GGD. However, body weight were significantly increased dose dependently by GGD treatment. Conclusions : These results suggest that GGD treatment suppresses immune responses to ovalbumin, and these properties may contribute to allergic disease care.

• KIPS Transactions on Software and Data Engineering
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• v.12 no.4
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• pp.189-198
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• 2023

As crimes frequently occur on the street, the spread of CCTV is increasing. However, due to the shortcomings of passively operated CCTV, the need for intelligent CCTV is attracting attention. Due to the heavy system of such intelligent CCTV, high-performance devices are required, which has a problem in that it is expensive to replace the general CCTV. To solve this problem, an intelligent CCTV system that recognizes low-quality images and operates even on devices with low performance is required. Therefore, this paper proposes a Saying CCTV system that can detect threats in real time by using the AWS cloud platform to lighten the system and convert images into text. Based on the data extracted using YOLO v4 and OpenPose, it is implemented to determine the risk object, threat behavior, and threat situation, and calculate the risk using machine learning. Through this, the system can be operated anytime and anywhere as long as the network is connected, and the system can be used even with devices with minimal performance for video shooting and image upload. Furthermore, it is possible to quickly prevent crime by automating meaningful statistics on crime by analyzing the video and using the data stored as text.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.49 no.1
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• pp.39-46
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• 2023

In this study, Crocus chrysanthus (Herb.) Herb. bulb extracts were extracted by purified water and ethanol, and their antioxidant and tyrosinase inhibitory activity were measured to see the possibility as a cosmetic material. The yield of the extracts was 1.8% to 6.0%, and the yield decreased as the ethanol concentration increased. DPPH free radical (1,1-diphenyl-2-picrylhydrazyl) scavenging activity was high at 91.97% at 625 ㎍/mL of 70% ethanol extract. The total phenol content was also measured at 447 mg/g, higher than other extraction methods. The whitening effect was confirmed through in vitro tyrosinase inhibitory activity. As the ethanol concentration of the extracts increased, the tyrosinase inhibitory activity increased, and 70% and 94.5% ethanol extracts showed high inhibitory activity. Therefore, the Crocus chrysanthus (Herb.) Herb. bulb extracts confirmed its potential as a cosmetic material through antioxidant and whitening effects.

• Animal Bioscience
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• v.36 no.6
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• pp.943-952
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• 2023

Objective: For decades, LYD ([Landrace×Yorkshire] ♀×Duroc ♂) pigs are the most commonly-used commercial breed for meat production in Korea. Recently, due to the increasing demand for premium pork, the National Institute of Animal Science (Korea) has synthesized a novel pig breed named Woori Heukdon (WHD). This study aimed at comparing the carcass traits, meat yield and quality characteristics between the LYD and WHD pigs under identical rearing condition. Methods: The WHD and LYD pigs (n = 15 each) were reared under identical conditions and fed the same commercial diet until reaching recommended market weight (100 to 120 kg). After slaughter, the carcasses were evaluated for traits and meat yield, and the meat quality was assessed on shoulder butt and belly cuts. Results: Although no significant differences (p>0.05) occurred in slaughter weight between two pig types, WHD had a lower meat yield (by about 6 kg corresponding to approximately 7%) compared to the LYD pigs (p<0.05). The WHD had a higher fat content (by 4.26% and 13.52% in the shoulder butt and belly, respectively) compared to those of LYD pigs (p<0.05). The WHD meat showed a lower cooking loss and higher a* (redness) value (p<0.05). The WHD belly had a significantly (p<0.05) higher oleic acid content and concentrations of nonanal, octanal and decanal associated with fatty odor while, the LYD meat had a higher number of pyrazines associated with roasty odor. Regarding sensory quality, higher flavor, juiciness, and acceptability higher scores were given for the WHD meat than for the LYD meat (p<0.05). Conclusion: Under identical rearing conditions the WHD exhibited a better meat quality and sensory properties. However, the use of this diet resulted in a high fat level that may be associated with high trimming loss for the WHD.

• Journal of dental hygiene science
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• v.23 no.1
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• pp.29-38
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• 2023

Background: The purpose of this study was to investigate the effect of salad dressings on the flowable composite resin surface and the erosion-inhibitory effect of calcium. Methods: The experiment included six groups: oriental dressing, balsamic dressing, lemon-garlic dressing, lemon-garlic dressing supplemented with 3% calcium, mineral water as a negative control group, and orange juice as a positive control group. pH and titratable acidity were measured. The prepared specimens were immersed in the experimental solutions for 1, 3, 5, 15, and 30 minutes. The surface microhardness was measured using the Vickers hardness number before and after the treatment, and the surface of the specimens was observed using a scanning electron microscope (SEM). Results: The pH values of the experimental groups in increasing order were as follows: lemon-garlic dressing (2.49±0.03), balsamic dressing (3.12±0.06), lemon-garlic dressing +3% calcium (3.27±0.09), oriental dressing (3.75±0.03), orange juice (3.82±0.02), and mineral water (7.32±0.16). The largest surface hardness reduction value was shown in lemon-garlic dressing (-9.61±1.16), followed by balsamic dressing (-9.17±1.63), oriental dressing (-8.62±1.09), orange juice (-8.19±1.36), lemon-garlic dressing +3% calcium (-6.76±1.23), and mineral water (-1.63±2.47). According to the SEM findings, the experimental and positive control groups showed rough surfaces and micropores, whereas the negative control group showed a smooth surface. Moreover, the lemon-garlic dressing with +3% calcium showed fewer micropores and a smoother surface than the lemon-garlic dressing. Conclusion: The intake of salad dressings at a low pH could weaken the surface microhardness of the flowable composite resin. However, adding calcium to these salad dressings can reduce the risk of microhardness reduction on the flowable composite resin surface.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.43 no.3
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• pp.337-352
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• 2023

In general, Rainfall-Runoff model parameter set is optimized using the entire data to calculate unique parameter set. However, Korea has a large precipitation deviation according to the season, and it is expected to even worsen due to climate change. Therefore, the need for hydrological data considering seasonal characteristics. In this study, we conducted regional sensitivity analysis(RSA) using the conceptual Rainfall-Runoff model, GR4J aimed at the Soyanggang dam basin, and clustered combining the RSA results with hydrometeorological data using Self-Organizing map(SOM). In order to consider the climate characteristics in parameter estimation, the data was divided based on clustering, and a calibration approach of the Rainfall-Runoff model was developed by comparing the objective functions of the Global Optimization method. The performance of calibration was evaluated by statistical techniques. As a result, it was confirmed that the model performance during the Cold period(November~April) with a relatively low flow rate was improved. This is expected to improve the performance and predictability of the hydrological model for areas that have a large precipitation deviation such as Monsoon climate.

• Korean Journal of Food Science and Technology
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• v.54 no.1
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• pp.28-34
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• 2022

Glioblastoma is the most common primary malignant brain tumor and has an extremely poor prognosis. Glioblastoma stem cells (GSCs) contribute to tumor initiation, recurrence, and resistance to therapy, and are thus a key therapeutic target. The peel of Citrus unshiu Markovich has been used in traditional medicine in East Asia to treat various diseases. In this study, we investigated the anticancer activity and molecular mechanism of the chloroform extract of this natural product (CECU) in U87MG GSCs. The results show that CECU inhibited the proliferation, tumorsphere formation, and migration of U87MG GSCs by causing cell cycle arrest at the G0/G1 phase and apoptosis. In addition, CECU downregulated key cancer stemness regulators, including CD133, Oct4, Nanog, integrin α6, ALDH1A1, and STAT3 signaling in U87MG GSCs. Furthermore, CECU significantly suppressed in vivo tumor growth of U87MG GSCs in a chorioallantoic membrane model. Therefore, CECU can be utilized as a natural medicine for the prevention and treatment of glioblastoma.

• The Journal of the Korea Contents Association
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• v.22 no.5
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• pp.350-366
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• 2022

The objective of this study is to empirically verify the relationship between the image of politicians, political belief agreement, and voting intention recognized through YouTube content, centering on the 4·7 Seoul Mayor's Election. A survey was conducted on voters in their 20s or older living in Seoul, and the following main results were derived. First, among the factors of politician image, morality, leadership, and administrative power were found to have a significant positive effect on political belief agreement. Second, it was found that the consensus of political beliefs with politicians had a significant positive effect on voters' voting intentions. Third, it was found that among the factors of politician image, political ability and communication ability had a directly significant positive effect on voting intention. Fourth, it was found that politicians' morality, leadership, and administrative power all had a significant effect on voters' voting intentions through political consensus. The significance of this study is that this study identified the factors of politician image on political belief agreement and voter voting intention by applying the relationship between politician image, political belief agreement, and voter voting intention to YouTube content.

• Design Convergence Study
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• v.15 no.3
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• pp.117-131
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• 2016

The introduction of comprehensive programming channels has led to a diversity in the viewers' tastes and excessive competition between TV channels. Demand for channels on well-being is also increasing, due to the well-being and green consumption trends. This study conducted a case study on domestic and international channel branding strategies as well as an analysis on Korean channels focusing on well-being and lifestyle and found that there are no TV channels which provides comprehensive well-being information on food, clothing and housing at the moment in Korea. This study further discovered that information on such topics are currently provided in a tidbit fashion via educational or entertainment programs. Therefore, this study presented strategies for a well-being lifestyle channel brand and designed the brand mark and a station ID for the channel. This study conducted a survey targeting 50 men and women over 20 who have participated in environment-related projects for an objective verification of the channel brand strategies and design. The survey showed that the respondents were generally positive towards the necessity of the channel and of the content presented by this researcher. Some of the respondents, however, pointed out that the readability of the brand mark needs to be improved. This was reflected in the improved design and a survey comparing the two designs showed positive results. The results of this study will contribute to the launch of a well-being lifestyle channel targeting green consumers in the future.

• Design Convergence Study
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• v.14 no.5
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• pp.1-14
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• 2015

The purpose of this research is to analyze the current status of hospital life guides in Korean and overseas hospitals, draw problems, and propose a design improvement. in order to improve the visual convenience and efficiency of information delivery of hospital life guidelines. As a result of examining and analyzing the current status of the notice on hospital life in 16 hospitals at home and abroad, problems such as information selection without certain standard, increase of items due to unnecessary items, and forms that do not consider the convenience for notice use were discovered. In order to solve them, this study suggested a survey questionnaire for finding detailed improvements, and it divided the participants into two groups of 50 patients/nurses and 50 nurses in each. The study carried out a user awareness investigation and survey on the efficiency and understanding of information, number and importance of items, and color and form, and then made another sample notice to conduct a detailed survey on color and form. As a result, the study could identify that important items for each users were different. It is considered that a new design with improved visual convenience of users and efficiency of information delivery, by applying layout and graphic elements as well as selecting information that meets consumer demand, will be proposed based on this.