• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제18권2호
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• pp.138-144
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• 2007

Objectives: The aim of this study was to evaluate the reliability and validity of the Korean Version of the Diagnostic Interview Schedule for Children Version IV(DISC-IV), a highly structured diagnostic interview used to assess more than 30 psychiatric disorders in children and adolescents. Methods: A total of 91 study subjects, including 67 subjects who visited the child and adolescent psychiatry outpatient clinic at our institution and 24 community-based subjects, were assessed using the Korean Version of the DISC-IV. Clinical diagnosis was used as a gold standard for the examination of the validity of the DISC-IV. Forty-four of the study subjects were randomly selected for test-retest reliability measurement. Results: The validity of the Korean Version of the DISC-IV showed kappa values ranging from 0.25 to 0.40 in the clinical sample and 0.65 to 1.00 in the community sample. The sensitivities varied according to the diagnostic categories, but the specificities were excellent for all diagnostic entities. Conclusion: The Korean Version of the DISC-IV showed good reliability and validity in Korean children and adolescents. The Korean Version of the DISC-IV might be a useful tool for assessing psychiatric disorders in children and adolescents.

• 한국산학기술학회논문지
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• 제13권1호
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• pp.236-246
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• 2012

지역 환자의 역외유출 현상이 갈수록 심화되고 있다. 특히 중증질환을 가진 암 환자는 거리와 상관없이 양질의 의료서비스를 받기 위해 수도권 의료기관을 많이 찾는다. 하지만 이러한 환자의 역외유출은 진료 연속성 저하와 함께 불필요한 물적, 인적 이동을 야기 시킨다. 이에 본 연구는 부산지역 암환자들이 부산과 수도권에서 진료를 받는 경우에 환자의 만족도에 영향을 미치는 요인을 체계적으로 비교, 분석하여 지역 병원의 이용도를 제고시킬 수 있는 방안을 마련하고자 수행하였다. 부산지역 암환자를 대상으로 부산 의료기관에서 수술을 받은 암환자 223명과 수도권에서 수술을 받은 암환자 187명을 대상으로 2011년 3월 21~3월 30일까지 설문조사를 실시하였다. 자료 분석은 SPSS및 SAS 프로그램을 이용하여 접근성, 의료진 만족도, 이용편의성이 의료서비스 전반적 만족도 요인으로 나누어 접근하였다. 연구 결과, 이용편의성과 의료진 만족도는 수도권 의료기관 이용자가 높은 것으로 나타났으나, 접근성과 의료서비스의 전반적 만족도는 부산지역 의료기관을 이용한 암환자가 높았다. 이에 부산지역 의료기관은 의료진의 질적 향상을 위한 우수 의료진 유치 및 양성, 환자 중심의 의료 시설 제공을 위한 노력이 필요하다. 본 연구를 토하여 향후 환자의 수도권 집중현상 완화를 위한 정책개발 시 유용한 기초자료로 활용할 수 있을 것으로 기대된다.

• 보건행정학회지
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• 제18권3호
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• pp.58-89
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• 2008

The purpose of this study was to evaluate comparatively the content of the Expanded National Immunization Program according to the provision method between 2005 and 2006 in Korea. We assessed the impact of the mutually exclusive vaccination policy using the result reports of the 2005 and 2006 Demonstration Project and the related references by the content analysis. The public health centers paid vaccination fees to the private clinic and hospital in the 2005 Demonstration Project in Daegu metropolitan city and Gunpo city. But, the public health centers directly supplied free vaccination services to the children in the 2006 Demonstration Project in Gangneung city, Yangsan city, and Yeongi-gun. The total budgets of 2005 and 2006 Demonstration Project were 6.57 billion won and 0.65 billion won, respectively. The computerized registration rates and timeliness rates of administration of each vaccination had improved all in the 5 Demonstration Project regions. However, the computerized registration rates of most vaccination in Gunpo city were higher than those in the 2006 Demonstration Project regions except hepatitis B. Especially, the computerized registration rate of BCG was 48.3%, but the BCG coverage rate by the follow-up telephone survey was 99.8% in Daegu metropolitan city. The community parents in all the regions were satisfied because of expanding financial and geographical access to immunization coverage. In conclusions, from the aspect of the main outcomes, the implementation of two different financial immunization aids appears to be widely accepted among these parents and to have had an impact on vaccination coverage. In the future, the government must try to enact that the national immunization policy including under-immunised or incompletely immunised groups would be achieved by the affordable method of the public-private dynamics.

• 한국대기환경학회지
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• 제34권4호
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• pp.534-541
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• 2018

Concentrations of total particulate matter (TPM), $PM_{10}$ and $PM_{2.5}$ were measured at three different sites based on each different fuel type (solid, liquid and gas) used in thermal power plants operating in Yeosu and Gwangyang National Industrial Complexes during 2017. The highest concentrations of TPM, $PM_{10}$, and $PM_{2.5}$ were observed at the solid fuel facility, and these values were $3.356mg/Sm^3$, $2.342mg/Sm^3$ and $1.834mg/Sm^3$, respectively. The ratio of $PM_{2.5}$ to TPM was the highest value of 54.6% in solid fuel case, and the lowest was 35.7% found in liquid fuel case. As a result of analyzing 9 kinds of metal compound with respect to each particle size, the metal concentration of TPM is higher than those of $PM_{10}$ and $PM_{2.5}$ in all fuel types. Total concentrations of metal elements in TPM by fuel difference are $1.2702mg/Sm^3$ in solid fuel, 0.0603 mg/Sm3 in liquid fuel, and $0.0733mg/Sm^3$ in gas fuel, respectively. Relatively higher total metal concentration in gas fuel than in liquid fuel was found; and this could be higher Cr and Al concentrations in use of gas fuel. As a result of estimating the emission factors of each facility, in case of solid fuel, TPM emissions per electricity production were found to be 0.7080 kt/PJ, followed by liquid fuel and gas fuel. $PM_{10}$ and $PM_{2.5}$ emissions per hour of electricity production were similar to those of TPM.

• 대한물리치료과학회지
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• 제19권3호
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• pp.49-56
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• 2012

Background : The purpose of this study is to understand the effects of ankle joint taping on balancing abilities of the elderly and to provide preliminary data on preventing falls among the elderly. Methods : In this study, 20 students(8 male, 12 female) in their 20s from D University as well as 14 elderly(4 male, 10 female) in their 70s from S community center have participated. The participants were well informed about the experiment and voluntarily participated. We measured the difference in balancing ability before and after taping between the two groups using methods such as standing on single-leg stance, TUG, and plantar pressure. Kinesio taping, a stop-watch, and the EMED-system were used as equipment along with the SPSS 12.0 program, with a significance level of 0.05, to test the difference before and after taping between the two groups. Result : First, the 70s group showed a significant increase in the dorsal flexion angle after taping. Second, the 70s group showed a significant increase in duration time of standing on one foot after taping. Third, the 70s group's TUG time was significantly shorter. Fourth, the maximum peak value for static and dynamic plantar pressure showed a significant decrease after taping; and dynamic plantar pressure area value decreased as well within significant range. Conclusion : The study has shown that taping is effective on static dynamic balancing ability of the elderly.

• 대한물리치료과학회지
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• 제18권1호
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• pp.11-19
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• 2011

Purpose: The purpose of this study is to understand the effect of balance and gait when simultaneous application of Kinesio Taping on the lower extremities is done to improve the pattern of hemiplegic patients asymmetric lower extremity. Methods: This study was performed with 7 patients who have hemiplegia symptoms due to stoke. The taping on the paralyzed side was done on tibialis anterior, gluteus medius, gluteus maximus and psoas major and the taping on the unparalyzed side was done on the calf muscle and quadriceps. Berg Balance Scale(BBS) and Time Up and Go Test(TUG) was used to assessment the balance and gait of the patient after the kinesio taping was done on the lower extremities. The results of the test was analyzed by Wilcoxon Signed Rank Test on SPSS(Ver. 10.1). Results: When the taping was done on the paralyzed side, there was a significant improvement of balance and gait in BBS and TUG. When the taping was done on the lower extremities, it showed significant improvement of balance and gait, compared to when the taping was only done on the paralyzed side, according to BBS and TUG. Conclusion: The result of this study shows that the simultaneous taping of the lower extremities of the hemiplegic patients improves balance and gait by improving the pattern of patients lower extremities.

• Journal of Preventive Medicine and Public Health
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• 제35권4호
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• pp.295-304
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• 2002

Objectives : This study was carried out to investigate the cause, magnitude and transmission route of the cholera outbreak in 2001 Methods : The study population were those persons who ingested foods at the restaurant, were confirmed as cholera patients, had symptoms of diarrhea and sewed as workers at the restaurant. A questionnaire survey and microbiological examinations on the microbes isolated from rectal swabs were conducted. Of the cases, 316 food histories were surveyed by an analysis of the restaurant menu. Results : There were 139 confirmed cases of cholera reported in Korea in 2001. Of these, 104 were related to the restaurant. By region, Gyeongsangbuk-do had the highest incidence with 91 cases. Of these 91 cases, 74 had ingested foods at the restaurant, 2 were employees and 3 were secondary infection cases within the families. The results of the odds ratio analysis of the 316 persons having ingested foods at the restaurant were as follows: sandwiches 5.07 (95% CI, 1.85-14.59), soybean curd 2.45 (95% CI, 1.09-5.56), noodles 2.34 (95% CI, 1.24-4.42), steamed squid 2.01 (95% CI, 1.17-3.47) and vinegared rice 1.82 (95%, CI, 1.08-3.09). It was certain the restaurant in question was the cause of the 2001 outbreak. Conclusions : We suspected that more than one restaurant employee contaminated foods served at the restaurant. In addition, eating raw fishes purchased at the Pohang Fisheries infected the employees of the restaurant. There is a possibility that these raw fishes were themselves contaminated by cholera bacilli in the sea.

• Journal of Korean Medical Science
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• 제33권52호
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• pp.336.1-336.12
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• 2018

Background: We aimed to investigate mucosal immunity related to forkhead box P3 ($FOXP3^+$) regulatory T (Treg) cells, T helper 17 (Th17) cells and cytokines in pediatric inflammatory bowel disease (IBD). Methods: Mucosal tissues from terminal ileum and colon and serum samples were collected from twelve children with IBD and seven control children. Immunohistochemical staining was done using anti-human FOXP3 and anti-$ROR{\gamma}t$ antibodies. Serum levels of cytokines were analyzed using a multiplex assay covering interleukin $(IL)-1{\beta}$, IL-4, IL-6, IL-10, IL-17A/F, IL-21, IL-22, IL-23, IL-25, IL-31, IL-33, interferon $(IFN)-{\gamma}$, soluble CD40L, and tumor necrosis factor-${\alpha}$. Results: $FOXP3^+$ Treg cells in the lamina propria (LP) of terminal ileum of patients with Crohn's disease were significantly (P < 0.05) higher than those in the healthy controls. $ROR{\gamma}t^+$ T cells of terminal ileum tended to be higher in Crohn's disease than those in the control. In the multiplex assay, serum concentrations (pg/mL) of IL-4 ($9.6{\pm}1.5$ vs. $12.7{\pm}3.0$), IL-21 ($14.9{\pm}1.5$ vs. $26.4{\pm}9.1$), IL-33 ($14.3{\pm}0.9$ vs. $19.1{\pm}5.3$), and $IFN-{\gamma}$ ($15.2{\pm}5.9$ vs. $50.2{\pm}42.4$) were significantly lower in Crohn's disease than those in the control group. However, serum concentration of IL-6 ($119.1{\pm}79.6$ vs. $52.9{\pm}39.1$) was higher in Crohn's disease than that in the control. Serum concentrations of IL-17A ($64.2{\pm}17.2$ vs. $28.3{\pm}10.0$) and IL-22 ($37.5{\pm}8.8$ vs. $27.2{\pm}3.7$) were significantly higher in ulcerative colitis than those in Crohn's disease. Conclusion: Mucosal immunity analysis showed increased $FOXP3^+$ T reg cells in the LP with Crohn's disease while Th17 cell polarizing and signature cytokines were decreased in the serum samples of Crohn's disease but increased in ulcerative colitis.

• 해양환경안전학회:학술대회논문집
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• 해양환경안전학회 2008년도 춘계학술발표회
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• pp.185-189
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• 2008

동계 한반도의 기후에 큰 영향을 미치는 한랭 건조한 대륙성고기압이 서해를 거쳐 한반도의 확장해 올 때 서해 연안지역의 적설량과 서해의 해황이 어떻게 상호 영향을 미치는가를 알아보았다. 서해 연안지역의 적설량은 인천은 1월, 2월과 12월, 군산과 목포는 1월, 12월과 2월 순으로 적설량이 많다. 한랭 건조한 대륙기단의 중심이 서해를 통과하는 경우가, 서해를 통과하지 않는 경우보다 인천지역에서는 약 3.4배, 군산에서는 약 2.3배 정도를 해양으로부터 많은 열을 흡수한다. 또한, 서해 연안지역에서 1일 10 cm 이상의 대설이 발생한 기간에는 잠열속과 현열속에 의한 방출열량이 약 $100W/m^2$ 이상이다. 대설이 발생한 시기의 기압배치는 중국 북부 지방이나 중부 지방에 고기압이 위치하고, 동해상이나 일본 열도상에 저기압이 존재하여 서해 또는 한반도에서 전선이 형성되는 서고동저형의 특징을 보인다. 한편, 대설이 발생한 기간동안 서해 연안지역의 풍향은 북풍 또는 북서풍이 우세하고, 풍속은 $4\sim8m/sec$ 정도이다.

• 한국약용작물학회지
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• 제28권6호
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• pp.395-411
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• 2020

Background: This study investigated the anti-obesity effect of the flavonoid rich fraction (FRF) and its constituent, rutin obtained from the leaf of Morus alba L., on the lipid accumulation mechanism in 3T3-L1 adipocyte and C57BL/6 mouse models. Methods and Results: In Oil Red O staining, FRF (1,000 ㎍/㎖) treatments showed inhibition rate of 35.39% in lipid accumulation compared to that in the control. AdipoRedTM assay indicated that the triglyceride content in 3T3-L1 adipocytes treated with FRF (1,000 ㎍/㎖) was reduced to 23.22%, and free glycerol content was increased to 106.04% that of the control. FRF and its major constituent, rutin affected mRNA gene expression. Rutin contributed to the inhibition of Sterol regulatory element binding protein-1c (SREBP-1c) gene expression, and inhibited the transcription factors SREBP-1c, peroxisome proliferator-activated receptor gamma (PPAR-γ), CCAAT/enhancer binding protein α (C/EBPα), fatty acid synthase (FAS) and acetyl-CoA carboxylase (ACC). In addition, the effect of FRF administration on obesity development in C57BL/6 mice fed high-fat diet (HFD) was investigated. FRF suppressed weight gain, and reduced liver triglyceride and leptin secretion. FRF exerted potential anti-inflammatory effects by improving insulin resistance and adiponectin levels, and could thus be used to help counteract obesity. The mRNA expressions of PPAR-γ, FAS, ACC, and CPT-1 were determined in liver tissue. Quantitative real-time PCR analysis was also performed to evaluate the expression of IL-1β, IL-6, and TNF-α in epididymal adipose tissue. Compared to the control group, mice fed the HFD showed the up-regulation in PPAR-γ, FAS, IL-6, and TNF-α genes, and down-regulation in CPT1 gene expression. FRF treatement markedly reduced the expression of PPAR-γ, FAS, IL-6, and TNF-α compared to those in HFD control, whereas increased the expression level of CPT1. Conclusions: These results suggest that the FRF and its major active constituent, rutin, can be used as effective anti-obesity agents.