• 식물병연구
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• 제15권1호
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• pp.36-40
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• 2009

본 연구는 꽃 양배추의 유기재배에 적합한 품종을 선발하기 위하여 원예적 특성이 우수하면서 검은썩음병에 저항성인 꽃양배추를 선발하기 위하여 실험을 수행하였다. 2006년 강원도 고랭지인 평창군 도암면과 강릉시 왕산면에서 조중생종 11개 품종과 중만생종 2개 품종의 원예적 특성을 조사한 결과 두 포장 모두에서 에브리부로, 탐스런, 녹제, 필그림이 우수하였다. 검은썩음병에 대한 품종간 저항성 반응은 품종에 따라서 두 포장에서 다르게 나타나 두 포장에 병원균의 race 분포가 다른 것으로 생각된다. 두 포장 모두에서 중생종인 에브리부로와 중만생종인 녹국은 검를썩음병에 대하여 저항성인 것으로 나타났다. 이 두 품종은 원예적 특성도 우수하였으므로 강원도 고랭지 유기재배에 적합할 것으로 사료된다.

• IMMUNE NETWORK
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• 제8권3호
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• pp.82-89
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• 2008

Background: Although a skin test is the primary option for detecting allergen-specific IgE in clinics, the serum IgE immunoassay is also important because it allows for the diagnosis of allergy without any accompanying adverse effect on the patient. However, the low detection limit of IgE levels by immunoassay may restrict the use of the method in some occasions, and improving its sensitivity would thus have a significant implication in allergy-immunology clinics. Methods: In this study, we attempted to detect specific serum IgE by using immuno-polymerase chain reaction (IPCR) which combines the antigen-antibody specificity of enzyme-linked immunosorbent assays (ELISAs) with the amplification power of PCR. Results: Our results demonstrated that Blo t5-specific serum IgE can be detected by IPCR with a 100-fold higher sensitivity than ELISA, and cross-reactivity of serum IgE to other mite allergens is able to be analyzed by using only $0.3{\mu}l$ of serum sample. Use of real-time IPCR seemed to permit more convenient determination of specific serum IgE as well. Conclusion: We believe that IPCR can serve as a valuable tool in determining specific serum IgE, especially when the amount of serum sample is limited.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2008년도 한국컴퓨터종합학술대회논문집 Vol.35 No.1 (C)
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• pp.80-84
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• 2008

DSMS는 USN과 같은 환경으로부터 스트림데이터를 실시간으로 입력 받아 등록된 연속질의를 처리하는 시스템이다. DSMS는 등록된 연속질의 처리를 위해 필요한 데이터를 버퍼에 관리하며, 스트림데이터의 저장기법에 따라 연속질의 처리 성능 및 버퍼 저장비용이 개선될 수 있으며, DSMS에서 연속질의는 특정 스트림데이터에 대해 일정한 기간 동안의 평균 값, 최대 소 값, 누적 값 등의 집계 연산을 요구하는 경우가 많다. 기존의 DSMS에서는 이러한 집계 연산이 필요한 연속질의의 효율적인 처리를 위해 LINT, BINT등의 자원 공유 집계 처리기법이 제안 되었다. 하지만 기존의 자원공유 집계 기법들은 위치 값을 포함하는 GeoSensing 데이터에 대한 고려를 하지 않았다. 본 논문에서는 공간 DSMS에서 공간영역질의 기반의 연속질의를 효율적으로 처리하기 위한 R-tree기반의 집계기법을 제안한다. 이는 각각의 연속질의에 포함된 공간 영역을 R-tree 인덱스로 구성하고, 연속질의에 필요한 공간 스트림데이터에 대한 집계값을 저장하여 연속질의를 처리하는 것이다. 제안기법은 공간 DSMS에서 공간영역 기반의 연속질의 처리 성능을 개선할 수 있으며, R-tree 기반으로 해당 영역에 대한 데이터 만을 버퍼에 관리하여 저장비용을 줄일 수 있다.

• Natural Product Sciences
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• 제14권1호
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• pp.21-26
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• 2008

The leaves of Acanthopanax species have traditionally been used as a tonic and a sedative as well as in the treatment of rheumatism and diabetes. Chiisanoside is the major active lupane triterpenoid of Acanthopanax leaves. To investigate the bioactivities of chiisanoside, which act on bone metabolism, the effects of chiisanoside on the function of osteoblastic MC3T3-E1 cells were studied. Chiisanoside $(0.02{\sim}20\;{\mu}M)$ significantly increased the growth of MC3T3-E1 cells and caused a significant elevation of alkaline phosphatase (ALP) activity, collagen content, and nodules mineralization in the cells (P < 0.05). The effect of chiisanoside (2 ${\mu}M$) in increasing ALP activity was completely prevented by the presence of tamoxifen, suggesting that the effect of chiisanoside might be partly estrogen receptor mediated. Moreover, cotreatment of p38 inhibitor SB203580 or JNK inhibitor SP600125 inhibited chiisanoside-mediated ALP upregulation, suggesting that the induction of differentiation by chiisanoside is associated with increased activation of p38 and JNK mitogen-activated protein kinases. Our data indicate that the enhancement of osteoblast function by chiisanoside may result in the prevention for osteoporosis.

• 대한한의학원전학회지
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• 제28권2호
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• pp.147-162
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• 2015

Objectives : The purpose of this study is to investigate splenic constipation syndrome(脾約證) in Shanghanlun by comparing 179 & 247 provisions. Methods : Including Shanghanlun, several texts which contain Cheng Wu-ji, Wan Mi-zhai, Qian Huang, Zhu Gong, Fang You-zhi, Yu Jia-yan, Zhang Lu, Cheng Ying-mao, Zhang Xi-ju, Chen Xiu-yuan, Wu Qian, Xu Ling-tai, You Zai-jing, Zhu Dan-xi's opinion about the splenic constipation syndrome were chosen and comparative consideration was carried out. Results & Conclusions : The following conclusions could be drawn. 247 provisions in Shanghanlun is different from 179 provisions because the beginning of the each splenic constipation syndrome is different. The difference between 179 & 247 provisions are proved by comparing Mild Purgative Decoction which is used Taiyangyangming splenic constipation syndrome and Fructus Cannabis Pill which is used Dorsal pedal pulse splenic constipation syndrome. Cheng Wu-ji's opinion that 179 & 247 provisions is different is meaningful because he is first investigated the different beginning of the splenic constipation syndrome. Several annotator's opinion which oppose Cheng Wu-ji is majority and they set a high value on Jangbu(臟腑) factor. Several annotator's opinion which agree Cheng Wu-ji is minority and they set a high value on splenic constipation syndrome also begins from Taiyangbing. The concept of overlapping of Taiyangyangming is different from the concept of Taiyangyangming. Consequently 179 & 247 provisions has to be distinguished.

• Journal of Ginseng Research
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• 제35권1호
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• pp.39-44
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• 2011

We studied the acute oral toxicity of black ginseng (BG) produced by heat process in rats. Single acute BG extract doses of 0, 5, 10, and 15 g/kg dissolved in saline were administered by oral gavage and the animals were kept under observation for 14 days. The single administration of BG extract up to 15 g/kg did not produce mortality, behavioral change or abnormal clinical signs in the rats. These results indicated that the oral $LD_{50}$ of the BG extract in the rats is higher than 15 g/kg. Compared to the control group, no treatment-related biologically significant effects of BG extract were noted in the measurements of the body weight or food intake. At the end of the period, the biochemical parameters and hematological parameters were analyzed in the plasma and blood. A histopathological examination of the liver and kidney was also conducted. Only the blood nitrogen urea and potassium levels in the biochemical indices showed significant differences at 10 and 15 g/kg doses of BG extract compared to the control group. These changes were not considered to be due to the toxicity. None of the other clinical chemistry parameters were affected. Therefore, these results indicate that the BG by heat processing is virtually nontoxic.

• Bulletin of the Korean Chemical Society
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• 제25권1호
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• pp.59-62
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• 2004

The ammonium ion-selective electrodes ($NH^+_4$-ISEs) based on the tetrahydrofuran(THF)-containing-16-crown-4 derivatives,1,4,6,9,11,14,16,19-tetraoxocycloeicosane ($L^1$) and 5,10,15,20,-tetramethyl-1,4,6,9,11,14,16,19-tetraoxocycloeicosane ($L^2$), were prepared and the electrode characteristics were tested. The conditioned $NH_4^+$-ISEs (E1) based on $L^1$ with TEHP as a plasticising solvent mediator gave best results with near-Nernstian slope of 53.9 mV/decade of activity, detection limit of $10^{-4.9}$ M, and enhanced selectivity coefficients for the $NH^+_4$ ion with respect to an interfering $K^+$ ion (log $K^{pot}_{NH_4^+,K^+}$ = -1.84). This result was compared to other ammonium ionophores reported previously, for example, that of nonactin (log $K^{pot}_{NH_4^+,K^+}$ = -0.92). The proposed electrode showed no significant potential changes in the range of 3.0 < pH < 9.0.

• Nuclear Engineering and Technology
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• 제44권5호
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• pp.507-522
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• 2012

When decommissioning a nuclear power plant, it is difficult to make an appropriate plan to ensure sufficient space for temporary placement and conveyance operations of dismantling targets. This paper describes a system to support temporary placement and conveyance operations using augmented reality (AR). The system employs a laser range scanner to measure the three-dimensional (3D) information of the environment and a dismantling target to produce 3D surface polygon models. Then, the operator simulates temporary placement and conveyance operations using the system by manipulating the obtained 3D model of the dismantling target in the work field. Referring to the obtained 3D model of the environment, a possible collision between the dismantling target and the environment is detectable. Using AR, the collision position is presented intuitively. After field workers evaluated this system, the authors concluded that the system is feasible and acceptable to verify whether spaces for passage and temporary storage are sufficient for temporary placement and conveyance operations. For practical use in the future, some new functions must be added to improve the system. For example, it must be possible for multiple workers to use the system simultaneously by sharing the view of dismantling work.

• 분석과학
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• 제32권2호
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• pp.48-55
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• 2019

The simple and effective analytical method for the quality control of a novel scalp tonic formulation has been developed and optimized in terms of HPLC conditions and sample preparation method, meanwhile, the optimization of preparation condition was using response surface methodology (RSM) based on central composite design (CCD). Oleanolic acid was selected as marker compound because of its bioactivities for alopecia therapy. The developed analytical method and extraction condition were successfully qualified. Coefficient of determination ($r^2$) for the calibration was 0.9997 with a line passing through the origin point in the range of 0.1-100 mg/mL. The limit of detection (LOD) and the limit of quantitation (LOQ) were 17.5 ng/mL and 55.0 ng/mL, respectively. The intra-day and inter-day precision of the method were 0.5-1.4 % and 0.7-1.8 % in relative standard deviation, respectively, while those accuracy were 99.5-100.9 % and 100.0-102.2 %, respectively. The repeatability of oleanolic acid in samples ranged of 0.3-1.9 % based on peak area and 0.3-0.7 % for retention time. Recoveries from samples were 95.0-99.4 % with lower than 1.8 % in relative standard deviation. Overall, the developed analytical method will be used for quality control of this commercial scalp tonic products successfully.

• 한국콘텐츠학회논문지
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• 제21권4호
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• pp.205-219
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• 2021

본 연구는 인공지능(AI) 기술을 기반으로 제작된 뉴스 앵커의 시청자 수용에 영향을 미치는 선행 요인 조사를 목적으로 하였다. AI 뉴스 앵커에 대한 지각된 신뢰와 지각된 유용성, 의인화, 사회적 실재감, 그리고 이해도를 포함하는 5개의 선행요인이 사용자 수용에 영향을 미칠 것으로 예상하였다. 그리고 AI 뉴스 앵커로부터 지각하는 능력과 호의, 진실성은 신뢰를 형성하는 선행요인으로 예측하였다. 연구모형과 연구가설을 통계적 유의수준에서 검증하기 위하여 513명의 조사 대상자로부터 설문 데이터를 수집하였다. 데이터의 정규성과 동일방법편의, 내적 일관성 평가와 함께 탐색적 요인분석과 확인적 요인분석을 포함한 척도 순화 프로세스를 수행하였다. 구조방정식 모형 분석을 수행한 결과, AI 뉴스 앵커로부터 지각하는 신뢰와 지각된 유용성, 의인화는 시청자 수용에 유의한 정(+)의 영향을 미치는 것으로 나타났다. 그리고 AI 앵커로부터 지각한 능력과 진실성은 신뢰에 유의한 정(+)의 영향을 미치는 것으로 평가되었다.