• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6619-6625
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• 2014

Background: Numerous studies have explored the influence of XPD Lys751Gln and/or Asp312Asn polymorphisms on skin cancer susceptibility. However, the results remain inconclusive. To derive a more precise estimation, we conducted a comprehensive search to identify all available published studies and performed a meta-analysis. Materials and Methods: Electronic literature searches of the PubMed, CBM and CNKI databases were performed up to March 2014. Odds ratios (ORs) with 95% confidence intervals (CIs) were applied to assess the strength of associations. Results: Seventeen case-control studies were included with a total sample size of 6, 113 cases and 11, 074 controls for the XPD Lys751Gln polymorphism, and 10 studies (3, 840cases and 7, 637 controls) for the XPD Asp312Asn polymorphism were pooled for analysis. Overall, no significant associations were found between the XPD Lys751Gln polymorphism and skin cancer risk in any genetic model. On stratified analysis by tumor type, XPD Lys751Gln polymorphism was not associated with increased risk of non-melanoma skin cancer, but was significantly related with increased risk of cutaneous melanoma (Gln/Gln vs Lys/Lys: OR=1.15, 95%CI=1.02-1.29, p=0.023; dominant model: OR=1.09, 95%CI=1.01-1.18, p=0.036). For the XPD Asp312Asn polymorphism, no significant association with skin cancer risk was observed in overall or subgroup analyses. Conclusions: The present meta-analysis suggests that the XPD Lys751Gln polymorphism may contribute to the risk of cutaneous melanoma from currently available evidence. Further investigations are needed to obtain more insight into possible roles of these two polymorphisms in skin carcinogenesis.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.8
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• pp.3054-3067
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• 2015

The phenomena of higher channel cross polarization discrimination (XPD) is mainly observed for future wireless technologies such as small cell network and massive multiple-input multiple-output (MIMO) system. Therefore, utilization of high XPD is very important and space-polarization division multiple access (SPDMA) with dual-polarized MIMO system could be a suitable solution to high-speed transmission in high XPD environment as well as reduction of array size at base station (BS). By SPDMA with dual-polarized MIMO system, two parallel data signals can be transmitted by both vertically and horizontally polarized antennas to serve different mobile stations (MSs) simultaneously compare to conventional space division multiple access (SDMA) with single-polarized MIMO system. This paper analyzes the performance of SPDMA for maximum ratio transmission (MRT) in time division duplexing (TDD) system by proposed dual-polarized MIMO spatial channel model (SCM) compare to conventional SDMA. Simulation results indicate that how SPDMA utilizes the high XPD as the number of MS increases and SPDMA performs very close to conventional SDMA for same number of antenna elements but half size of the array at BS.

• Journal of the Korean Vacuum Society
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• v.2 no.2
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• pp.171-180
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• 1993

X-ray photoelectron diffraction (XPD) is used to characterize the crystallographically cleaved GaAs(110) surface. By using polar and azimuthal scans of the usual angle-resolved x-ray photoelectron spectroscopy, we get the reconstruction geometry of the clean GaAs(110) surface from the intensity ratio of Ga 3d core-level peaks. The reconstruction parameters are determined by fitting the diffraction pattern with the single scattering cluster (SSC) model, and the results show similar tendencies to those obtained by other techniques.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.7
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• pp.3299-3303
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• 2012

Objective: To investigate the association between xeroderma pigmentosum group D (XPD) Asp312Asn polymorphism and esophageal cancer (EC) susceptibility by meta-analysis. Methods: We searched PubMed up to April 9th, 2012, to identify relevant papers, and 8 published case-control studies including 2165 EC patients and 3141 healthy controls were yielded. Odds ratios (ORs) with relevant 95% confidence intervals (CIs) were applied to assess the association between XPD Asp312Asn polymorphism and EC susceptibility with the Comprehensive Meta-Analysis software, version 2.2. Results: Overall, the meta-analysis results suggested the XPD Asp312Asn polymorphism to be significantly associated with EC susceptibility [(Asn/Asn+Asp/Asn) vs. Asp/Asp: OR=1.20, 95%CI=1.05-1.36, p=0.01; and Asp/Asn vs. Asp/Asp: OR=1.15, 95%CI =1.01-1.31, p=0.04]. In the subgroup analysis by ethnicity and cancer type, significantly associations were found for Caucasian populations [(Asn/Asn+Asp/Asn) vs. Asp/Asp: OR=1.26, 95%CI =1.08-1.47, p<0.001; Asp/Asn vs. Asp/Asp: OR=1.19, 95%CI =1.02-1.40, p=0.03] and esophageal squamous cell carcinoma [(Asn/Asn+Asp/Asn) vs. Asp/Asp: OR=1.19, 95%CI=1.01-1.41, p=0.04]. There was no heterogeneity and no publication bias existed. Conclusions: This meta-analysis shows that the XPD Asp312Asn polymorphism may be a risk factor for developing EC, especially for Caucasian populations and esophageal squamous cell carcinoma.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.10 no.3
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• pp.199-205
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• 2017

In a small cell base station used in densely populated areas, a dual polarized multiple antenna(MIMO) is mainly used to increase the cell capacity. This paper demonstrates a dual-polarization antenna with high cross-polarization discrimination(XPD) that can improve the capacity of a small cell using a dual polarization multiple antenna (MIMO). By using the symmetric structure and differential feeding, high XPD in all directions is achieved. In addition, a very similar radiation pattern is observed between each polarization. Because of high XPD and similar radiation pattern in all directions, proposed antenna is well adopted for small-cell multiple-input multiple-output(MIMO) system. Experimental results shows that the proposed antenna has a bandwidth of 180 MHz (2.51~2.7 GHz), a maximum gain of 4.5 dBi (3.5~4.5 dBi), and a half-power beam width of 85 degrees. In addition, average XPD of 26.4 dB in all directions, more than 13.8 dB increase than previous dual-polarization antennas which use single emitter by using different feeding or selectively use polarization through switching.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.10 no.2
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• pp.302-311
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• 1999

In this paper, in order to suggest an optimal polarization diversity composition method in indoor radio wave propagation environments, the variation of the cross polarization discrimination(XPD) was theoretically analyzed by a computer simulation and compared to the actual measured data. From the results, it can be seen that the cross polarization discrimination of the case, a circularly polarized antenna was used at the transmitting end as well as the vertical and horizontal polarized antenna branches were used at receiving end (CV-CH), is lower than that of the case, horizontal polarized antenna at the transmitting end as well as the horizontal and vertical polarized antenna branches at the receiving end(HH-HV), and that of the case, vertical polarized antenna at the transmitting end as well as the vertical and horizontal polarized antenna branches at the receiving end(VV-VH). In this paper, to get more effective CV-CH polarization diversity composition, the amount of cross polarization discrimination values at the signals received by horizontal polarized antenna is compensated and the polarization diversity effect through the cumulative probability distribution is estimated. From the evaluation results, it was found that the polarization diversity effect was better at the compensated case than at the uncompensated case. On the other hand, it can be known that the polarization diversity effect is getting better as the cross polarization discrimination values are getting lower, and also be known that the effect can be improved if a transmitting antenna is composed of the ellipse polarized antenna by adjusting the axial ratio of the circularly polarized antenna and, a receiving antenna is made up of the vertical and horizontal polarized antenna branches.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.22
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• pp.9699-9706
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• 2014

Background: The predictive value of the xeroderma pigmentosum group D (XPD) Lys751Gln polymorphism regarding clinical outcomes of patients with colorectal cancer (CRC) receiving oxaliplatin-based chemotherapy has been evaluated in numerous published studies, but the results remain inconclusive. Therefore, we performed a meta-analysis to determine the precise role of the XPD Lys751Gln polymorphism in this clinical situation and optimize individual chemotherapy. Materials and Methods: A multiple search strategy was used to identify eligible studies. Pooled odds ratios (ORs), generalized odds ratio (ORG) and their 95% confidence intervals (CIs) were used to estimate the objective response, while hazard ratios (HRs) with 95%CIs were used for progression-free survival (PFS) and overall survival (OS). Results: A total of 17 studies including 2,286 patients met the inclusion criteria. Overall, the XPD 751Gln allele was associated with a non-significant reduced objective response to oxaliplatin-based chemotherapy in all patients or in the Asian and Caucasian subgroups. However, poor PFS and OS of CRC patients treated with oxaliplatin-based regimens were significantly related to the XPD 751Gln allele in the dominant model (PFS: HR=2.10, 95%CI: 1.65-2.67; OS: HR=3.18, 95%CI: 1.57-6.47). On stratified analysis by ethnicity, these relationships were more pronounced in Asians (PFS: HR=2.49, 95%CI: 1.79-3.47; OS: HR=5.25, 95%CI: 3.46-7.94) than in Caucasians (PFS: HR=1.73, 95%CI: 1.22-2.46; OS: HR=1.78, 95%CI: 1.06-2.99). Conclusions: The XPD Lys751Gln polymorphism may have prognostic value in patients with CRC undergoing oxaliplatin-based chemotherapy.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.11 no.3
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• pp.403-409
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• 2000

In this paper, we measured and analyzed cross polarization discrimination(XPD), signal correlation coefficient($\rho$) and received signal level decrease, for the application of polarization diversity scheme in the up-link of microcell environments. We experimented in a dense building area, a dense residence area, a market area, a school area and etc at 1.9 GHz. Cross polarization discrimination (XPD) is about 6~11 dB, signal correlation coefficient($\rho$) is below 0.7 and received signal level decrease is smaller than 3 dB. The results of comparing polarization diversity with space diversity show that polarization diversity gain is about 2~5 dB higher in the various area. As a results, polarization diversity scheme is more effective than space diversity scheme in microcell environments.

• Journal of electromagnetic engineering and science
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• v.6 no.1
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• pp.24-29
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• 2006

In this paper, we analyzed new two-branch polarization diversity at the receiving end of a mobile link which a transmitter emits circularly polarized wave. To analyze the correlation coefficient considered by XPD(Cross Polarization Discrimination) between the two received signals, a simple theoretical model of circular polarization diversity is adopted and experimental measurements are also conducted. From both theoretical and measurement results, it can be seen that the proposed circular polarization diversity scheme is more effective than that of the conventional linear polarization diversity.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.1
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• pp.231-236
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• 2013

Background: Published data regarding the association between xeroderma pigmentosum group D (XPD) Lys751Gln and Asp312Asn polymorphisms and gastric cancer susceptibility havew been inconclusive. This meta-analysis was therefore performed toobtain a more precise estimation of any relationship. Materials and Methods: A comprehensive literature search was conducted to identify all case-control studies of Lys751Gln and Asp312Asn polymorphisms and susceptibility to gastric cancer. Summary odds ratios (ORs) and its 95% confidence intervals (95% CIs) were calculated using a random-effects model with the software STATA (version10.0). Results: A total of 12 case-control studies including 3,147 cases and 4,736 controls were included. Overall, no significant associations were found in some models (for Lys751Gln: Lys/Gln vs Lys/Lys: OR=1.144, 95% CI=0.851-1.541, Gln/Gln vs Lys/Lys: OR=1.215, 95% CI = 0.740-1.955, dominant model: OR=1.137, 95% CI=0.818-1.582; recessive model: OR=1.123, 95% CI=0.765-1.650; for Asp312Asn: Asp/Asn vs Asp/Asp: OR=1.180, 95% CI=0.646-2.154, dominant model: OR=1.380, 95% CI = 0.812-2.346), but significantly elevated susceptibility was found for Asp312Asn polymorphism in some models (Asn/Asn vs Asp/Asp: OR=2.045, 95% CI=1.254-3.335, recessive model: OR=1.805, 95% CI =1.219-2.672), for the additive model, the XPD Lys751Gln and Asp312Asn polymorphisms were not significantly associated with gastric cancer susceptibility. In stratified analyses, significantly elevated susceptibility was found for some models in the Chinese population. Conclusion: This meta-analysis suggested the XPD Asp312Asn polymorphism might be a potential biomarker of gastric cancer susceptibility in overall population, while both XPD Lys751Gln and Asp312Asn polymorphisms might be risk factors of gastric cancer susceptibility in Chinese.