• Journal of the Korean Child Neurology Society
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• v.23 no.2
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• pp.45-50
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• 2015

Purpose: X-linked adrenoleukodystrophy (X-ALD) is a fatal, axonal demyelinating, neurodegenerative disease, and is caused by mutations the in ABCD1 (ATP-binding cassette transporter subfamily D member 1). Oxidative damage of proteins caused by very long chain fatty acid accumulating in X-ALD, is an early event in the neurodegenerative cascade. We evaluated valproic acid (VPA) as a possible option for oxidative damage in X-ALD. Method: We generated fibroblast of the childhood cerebral ALD from patient. We evaluated mRNA (ribonucleic acid) level of ABCD2 by real-time polymerase chain reaction, and reactive oxygen species (ROS) levels by flow cytometry. Results: VPA increased expression of ABCD2 in both control and ALD fibroblast. ABCD2 gene mRNA expression was increased 1.76 fold in normal fibroblasts, and 2.22 fold in the X-ALD fibroblasts. ROS levels were decreased in VPA treated X-ALD fibroblast, especially in treated with 1 mM of VPA. ROS levels revealed 13.7 in control fibroblast, on the other hand, 5.83 in X-ALD fibroblast treated with 1 mM of VPA. Conclusion: We propose VPA as a promising novel therapeutic approach in oxidant damage that warrants further clinical investigation in X-ALD.

• 전기의세계
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• v.38 no.8
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• pp.4-8
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• 1989

C.T의 출현은 그때까지의 X선 영상법이 3차원적 물체를 오차원적 영상으로 투영한 방법인데 반하여, 3차원 물체의 단면을 선택하여 2차원적 영상을 그대로 영상화하는 새로운 형태의 획기적인 방법으로 환자의 진단에 크게 공헌하고 있다. C.T의 기술은 급속하에 발전되어 현재 거의 기술정착단계에 도달했다고 할 수 있다. 이러한 C.T의 발전은 X선을 이용한 디지탈 영상진단 장치의 발전은 여러가지 형태로 나타나고 있다.

• The Journal of the Korean dental association
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• v.23 no.1 s.188
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• pp.8-8
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• 1985

• Bulletin of the Korean Chemical Society
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• v.20 no.8
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• pp.917-920
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• 1999

The three stereoisomers of the 6,13-bis(thymidinyl)dioxocyclam 6 were synthesized through photoreaction of the chromium alkoxycarbene complex 2 and 1-(benzyloxycarbonyl)-4,4-dimethyl-D 2 -imidazoline. The molecular structure of (R,S)-6 was elucidated by X-ray crystallography.

• Journal of Digital Convergence
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• v.11 no.8
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• pp.273-279
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• 2013

The purpose of the study was to present basic data to evaluation of the spatial resolution for exposure class(EC) in computed radiography(CR) by using the modulation transfer function(MTF). In this study, MTF was measured the edge method by using image plate(IP) of $100{\mu}mm$ pixels. A standard beam quality RQA5 based on an international electro-technical commission(IEC) standard was used to perform the X-ray imaging studies. Digital imaging began to set the sensitivity to EC 50, 100, 200, 300, 400, 600, 800, 1200 in X-ray irradiated to IP. The MTF 50% and 10% in the final images was analysis by using an authorized image analysis program the Origin 8.0 and the image J. As a results, the EC 200 was the best spatial resolution at MTF 50% ($1.979{\pm}0.114lp/mm$) and MTF 10% ($3.932{\pm}0.041$). Therefore, the EC 200 could be useful for the diagnosis of diseases that require high spatial resolution such as fractures.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.9 no.6
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• pp.539-545
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• 2016

In this paper, a novel coupled C type resonator is proposed for improvement of phase noise characteristics that is weak point of oscillator using planar type microstrip line resonator. Oscillator using proposed shorted coupled C type resonator is designed, it has improved phase noise characteristics. At the fundamental frequency of 9.8GHz, 4.87dBm output power and -84.7 dBc@100kHz phase noise have been measured for oscillator with shorted coupled C type resonator. Next, we designed voltage controlled oscillator using proposed shorted coupled C type resonator with varactor diode. The VCO has 33.8MHz tuning range from 9.7807GHz to 9.8145GHz, and phase noise characteristic is -115~-112.5dBc/Hz@100KHz. Due to its simple fabrication process and planar type, it is expected that the technique in this paper can be widely used for low phase noise oscillators for both MIC and MMIC applications.

• Applied Microscopy
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• v.35 no.4
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• pp.98-104
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• 2005

A FOV (field-of-view) of the HV-MSC (high voltage multi-scan CCD, $1024{\times}1024$ pixels) camera mounted in the post-column HV-GIF (high voltage gatan image filter) has been drastically enlarged by the projection lens current adjustment. An imaging area of the HV-MSC camera obtained at the lowest magnification (2,000x) is $112{\mu}m^2$ which corresponds to the recording area of the film at the magnification of 8,800x, while the achievable recording area is only $0.43{\mu}m^2$ at the same magnification without this technique. Ignoring the image distortion of less than 5%, we have designed an on-site reference graph to estimate projection lens currents for microscope magnifications above 8,800x, where the recording area on the HVMSC is same as that on the film.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.33 no.2
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• pp.189-194
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• 1988

To clarify the varietal differences of resistance to complete flooding, physiological characteristics in relation to flooding resistance in each growth stage of rice plants, the present study was carried out. The rate of survival after flooding at seeding stage of rice plants of the cultivar 'FR 13A' and Ind. X Jap. cultivars were 91.8% and 33.8% to 40%, respectively, while the Japonica varieties were completely dead. The tolerant varieties which has higher rate of survival showed the higher $O_2$ release, the higher catalase activity and lower peroxidase activity according to flooding treatment. Japonica type varieties showed the higher elongation of plant during flooding, lower recovery of flooding damage and the abrupt decrease of yield according to the increase of flooding periods in comparision to Ind. X Jap. crossed varieties when they were flooded at the active tillering stage. When rice plants were flooded at the booting stage, Ind. X Jap. crossed varieties had the higher photosynthesis, respiratory rate, root oxidizing power, ethylene evolution and lower yield reduction in comparision to japonica varieties.varieties.

• Bulletin of the Korean Chemical Society
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• v.23 no.12
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• pp.1754-1758
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• 2002

Tetrathiafulvalene(TTF) reacts with $PdCl_2,Pd(NO_3)_2$ and $Pd(hfacac)_2$(hexafluoroacetylacetonate) in ethanol to give $(TTF)_{1.5}PdCl_2$ (1a), $(TTF)_3Pd(NO_3)_2$ (1b) and $(TTF)_4Pd(hfacas)_2$ nd (1c), respectively. $PdCl(TCNQ)_{2.5}{\cdot}CH_3OH(2a)$was obtained from the reaction of $PdCl_2$ with LiTCNQ in methanol via the partial replacement of $Cl^-$ in $PdCl_2$ by $TCNQ^-$anion, whereas the total substitution of the labile $NO_3^-$ in $Pd(NO_3)_2$ yielded pd(TCNQ)·$CH_3OH$ (2b). $Pd(hfacac)_2(TCNQ)_2\cdot3CH_3OH$ (2c) was obtained from $Pd(hfacac)_2$ and LiTCNQ in methanol. The prepared compounds were characterized by spectroscopic (IR, UV, XPS) methods and magnetic (EPR, magnetic susceptibility) studies. The powdered electrical conductivities (${\sigma}_{rt}$) of the prepared compounds at room temperature were about~$10^{-7}S{\cdot}cm^{-1}$. The effective magnetic moments were lass than the spin-only value of one unpaired electron and no EPR signals from Pd metal ions were observed in any of the compounds, indicating that the Pd ions were diamagnetic and the magnetic moments arose from$(TTF)_n$ or $(TCNQ)_n$ moieties. The experimental evidences revealed that the charge transfer had occurred form $(TTF)_n$ moiety to the central Pd metal ion in 1a, 1b and 1c. Thus the TTF donors were ions in 2a and 2b were diamagnetic Pd(II) oxidation state. In contrast, the Pd metal ion was oxidized to Pd(IV) state in 2c as a result of an addition of $TCNQ^-$anion to $Pd(hfacac)_2$ in methanol. The oxidation states of the Pd metal ions were confirmed using the x-ray photoelectron spectroscopy.

• Journal of Magnetics
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• v.10 no.1
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• pp.14-22
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• 2005

Precisely refined Mossbauer study and nano structure observation revealed that intergranular phase formed between a-Fe and Nd₂Fe₁₄B phase in NdFeNbB alloys plays a significant role on the magnetic properties. The intergranular interaction was characterized in term of Henkel Plot (δM plot), and hyperfine field, quardrupole splitting and isomer shift were refined to predict the presence and role of the intergranular phase. By the addition of Nb into Nd₈Fe₈₆B₆ composition, coercivity was found to increase by 25% due to the refinement of average grain size of both the soft and hard magnetic phases which was decreased from 50 nm of virgin Nd/sub 8/Fe/sub 86/B/sub 6/ to 25 nm in Nd₈Fe ₈₅Nb₁B₆ alloys. The role of Nb addition was confirmed to stabilize the Nd₂Fe₁₄B lattice preventing from thermal vibration of the corresponding sites substituted Fe by Nb atoms in all sites in the Nd₂Fe₁₄B lattice. The enhanced coercivity was originated from the exchange hardening of soft and amorphous phases surrounding the hard magnetic Nd₂Fe₁₄B crystal.