• Journal of Korea Multimedia Society
• /
• v.15 no.10
• /
• pp.1205-1211
• /
• 2012

Recently, the evaluating method of the bone mineral density (BMD) in X-ray absorptiometry image has been studied for the early diagnosis of osteoporosis which is known as a metabolic disease. The BMD, in general, is evaluated by calculating pixel intensity in the bone segmented regions. Accurate bone region extraction is extremely crucial for the BMD evaluation. So, a X-Ray image enhancement is needed to get precise bone segmentation. In this paper, we propose an image enhancement method of X-ray image having multiple noise based sparse representation. To evaluate the performance of proposed method, we employ the contrast to noise ratio (CNR) metric and cut-view graphs visualizing image enhancement performance. Experimental results show that the proposed method outperforms the BayesShrink noise reduction methods and the previous noise reduction method in sparse representation with general noise model.

• Journal of Korea Multimedia Society
• /
• v.12 no.9
• /
• pp.1233-1241
• /
• 2009

Over the 50 percents of women who are older than 45 years have osteoporosis. Because people hardly recognize this disease by themselves, the researches that measure bone mineral density have been doing widely to detect osteoporosis in the early stage. The most widely used methods for bone mineral density measurement are based on the X-ray imaging. Among them, DEXA(Dual-energy X-ray Absorptiometry) imaging is one of the important methods in bone mineral density measurement. DEXA images are useful methods to increase diagnosis efficiency by reducing anatomic noise as two images obtained from two different energy levels. However, it has some problems to a calibration parameter determined by the heuristic method for bone extraction. In this paper, we propose the method to extract bone in DEXA image using calibration parameter based on anatomic attenuation coefficient. The experimental results reveal that the proposed method is effective.

• Imaging Science in Dentistry
• /
• v.47 no.4
• /
• pp.247-254
• /
• 2017

Purpose: Dual-energy X-ray imaging is widely used today in various areas of medicine and in other applications. However, no similar technique exists for dental applications. In this study, we propose a dual-energy technique for dental diagnoses based on voltage-switching. Materials and Methods: The method presented in this study allowed different groups of materials to be classified based on atomic number, thereby enabling two-dimensional images to be colorized. Computer simulations showed the feasibility of this approach. Using a number of different samples with typical biologic and synthetic dental materials, the technique was applied to radiographs acquired with a commercially available dental X-ray unit. Results: This technique provided a novel visual representation of the intraoral environment in three colors, and is of diagnostic value when compared to state-of-the-art grayscale images, since the oral cavity often contains multiple permanent foreign materials. Conclusion: This work developed a technique for two-dimensional dual-energy imaging in the context of dental applications and showed its feasibility with a commercial dental X-ray unit in simulation and experimental studies.

• Proceedings of the Korea Multimedia Society Conference
• /
• 2012.05a
• /
• pp.30-33
• /
• 2012

대사성 골 질환인 골다공증(Osteoporosis)의 조기 진단을 위해 X 선 영상에서 골 밀도를 측정하는 방법이 최근 연구되고 있다. 골 밀도는 X 선 영상에서 뼈가 분리되고, 분리된 영역에서의 픽셀에 의해 BMD가 측정되는데, 개선된 영상에서의 정밀한 뼈 추출이 주요한 요소이므로 X 선 영상의 개선은 골다공증의 조기 진단을 위해 필수적이다. 본 논문에서는 sparse 표현법을 도입하여 X 선 영상을 개선시키는 방법을 제안한다. 실험을 통해 제안한 방법의 결과가 기존의 방법인 웨이블릿 BayesShrink에 비해 개선됨을 CNR(Contrast to Noise Ratio)을 통해 확인하였다.

• Proceedings of the Korea Information Processing Society Conference
• /
• 2012.04a
• /
• pp.369-372
• /
• 2012

대사성 골 질환인 골다공증(Osteoporosis)의 조기 진단을 위한 골 밀도를 측정하는 방법이 최근 연구되고 있다. 골 밀도 영상은 이중 에너지 X 선 흡수법에 의해 측정되는데, 영상에 존재하는 잡음은 뼈 영역 추출과 골 밀도 계산에 어려움을 주고 있다. 따라서 본 논문에서는 최근 신호처리 분야에서 폭넓게 사용되고 있는 sparse 표현을 도입하여 X 선 영상의 잡음을 제거하는 방법을 제안한다. 실험을 통해 제안한 잡음 제거 방법의 결과가 기존의 방법에 비해 개선됨을 MSR(Mean to Standard deviation Ratio)과 CNR(Contrast to Noise Ratio)을 통해 확인하였다.

• The Transactions of The Korean Institute of Electrical Engineers
• /
• v.59 no.4
• /
• pp.823-830
• /
• 2010

This study was designed to examine the morphological measurement and characteristics of trabecullae based on femoral radiographic image for prediction of osteoporosis. Study subjects were 34 females (average age of 62.1 years) and 6 males (average age of 60.1 years), they were categorized into normal group and osteoporosis group in accordance with the T-score value. Measurement of the bone density of femoral bone was measured with DEXA(Dual Energy X-ray absorptiometry). ROI(Region of interests) was selected on femoral neck and trochanter. Characteristics of trabecullae was analyzed by using the skeletonization analysis of trabecular image. Morphological measurement was analyzed through femoral radiographic image in order to examine the correlation with osteoporosis. The result demonstrated statistically significant correlation between neck cortical thickness, shaft width, shaft cortical thickness, periphery, mean gray level and trabeculae area with BMD average (T-score) of femoral part. The results show that morphological measurement and characteristics of trabecullae based on femoral radiographic images for osteoporosis prediction could be effective.

• Journal of Korea Multimedia Society
• /
• v.19 no.8
• /
• pp.1248-1259
• /
• 2016

Classification methods based on dual energy X-ray absorptiometry, ultrasonic waves, and quantitative computed tomography have been proposed. Also, a classification method based on machine learning with bone mineral density and structural indicators extracted from the CT images has been proposed. We propose a method which enhances the performance of existing classification method based on bone mineral density and structural indicators by extending structural indicators and using principal component analysis. Experimental result shows that the proposed method in this paper improves the correctness of osteoporosis classification 2.8% with extended structural indicators only and 4.8% with both extended structural indicators and principal component analysis. In addition, this paper proposes a method of automatic phantom analysis needed to convert the CT values to BMD values. While existing method requires manual operation to mark the bone region within the phantom, the proposed method detects the bone region automatically by detecting circles in the CT image. The proposed method and the existing method gave the same conversion formula for converting CT value to bone mineral density.

• Journal of radiological science and technology
• /
• v.32 no.4
• /
• pp.361-370
• /
• 2009

The image quality management of bone mineral density is the responsibility and duty of radiologists who carry out examinations. However, inaccurate conclusions due to lack of understanding and ignorance regarding the methodology of image quality management can be a fatal error to the patient. Therefore, objective of this paper is to understand proper image quality management and enumerate methods for examiners and patients, thereby ensuring the reliability of bone mineral density exams. The accuracy and precision of bone mineral density measurements must be at the highest level so that actual biological changes can be detected with even slight changes in bone mineral density. Accuracy and precision should be continuously preserved for image quality of machines. Those factors will contribute to ensure the reliability in bone mineral density exams. Proper equipment management or control methods are set with correcting equipment each morning and after image quality management, a phantom, recommended from the manufacturer, is used for ten to twenty-five measurements in search of a mean value with a permissible range of ${\pm}1.5%$ set as standard. There needs to be daily measurement inspections on the phantom or at least inspections three times a week in order to confirm the existence or nonexistence of changes in values in actual bone mineral density. in addition, bone mineral density measurements were evaluated and recorded following the rules of Shewhart control chart. This type of management has to be conducted for the installation and movement of equipment. For the management methods of inspectors, evaluation of the measurement precision was conducted by testing the reproducibility of the exact same figures without any real biological changes occurring during reinspection. Bone mineral density inspection was applied as the measurement method for patients either taking two measurements thirty times or three measurements fifteen times. An important point when taking measurements was after a measurement whether it was the second or third examination, it was required to descend from the table and then reascend. With a 95% confidence level, the precision error produced from the measurement bone mineral figures came to 2.77 times the minimum of the biological bone mineral density change. The value produced can be stated as the least significant change (LSC) and in the case the value is greater, it can be stated as a section of genuine biological change. From the initial inspection to equipment moving and shifter, management must be carried out and continued in order to achieve the effects. The enforcement of proper quality control of radiologists performing bone mineral density inspections which brings about the durability extensions of equipment and accurate results of calculations will help the assurance of reliable inspections.

• Progress in Medical Physics
• /
• v.21 no.1
• /
• pp.70-77
• /
• 2010

This study tested how S/N (Signal to Noise Ratio) ratios and ADC (apparent diffusion coefficient) values vary with different T-scores in a group of patients with osteoporosis. Based on DEXA (Dual Energy X-ray Absorptiometry) T-scores for L1.L4 for two groups of subjects consisting of 30 healthy people without osteoporosis and 30 patients who came for treatment of waist (lumbar or low back) pain and were suspected to have osteoporosis as judged from the simple X-ray findings, this study classified every spine into two groups of osteoporosis and osteopenia. Signal intensity measurements were made in the four regions of L1 to L4 on diffusion-weighted MR images obtained using 1.5T MR scanner, while ADC measurements were obtained from ADC map images. As an approach for quantitative analysis, the comparison of the variances in S/N ratios and ADC values for varying T-scores in the selected regions of interest was carried out based on averaged T-scores, S/N ratios, and ADC values. Also, the variances in S/N ratios and ADC values for each of the groups of osteoporosis and osteopenia, which were classified into by T-scores, were compared. For qualitative analysis, a careful naked eye examination of signal intensity differences in the area of L4 was made on T1-weighted sagittal images for each of the healthy (normal), osteopenia, and osteoporosis groups. In the qualitative analysis, it was found that for both the osteopenia group and the osteoporosis group, as T-scores deceased, the S/N ratios on diffusion-weighted MR images also decreased, with the greatest decrease in the S/N ratio found in the osteoporosis group. Additionally, among the three groups, the lowest S/N ratio was found in the osteoporosis group. With respect to ADC map, it was found that for both the osteopenia group and the osteoporosis group, as T-scores deceased, the ADC values on diffusion-weighted MR images also decreased, with the greatest decrease in the ADC values found in the osteoporosis group. Additionally, among the three groups, the lowest ADC value was found in the osteoporosis group. On the other hand, in the qualitative analysis, the osteoporosis group showed the highest signal intensity. Additionally, among the three groups, the lowest signal intensity was found in the healthy (normal) group. It was found that as osteoporosis progressed, S/N ratio and ADC decreased, whereas signal intensity increased on T1-weighted images. Also, in diagnosing osteoporosis, MRI tests turned out to be (more) effective.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• v.23 no.2
• /
• pp.107-114
• /
• 2001

Objectives : To compare jaw bone density of young adults (control group) and post-menopausal women(experimental group) in periapical and panoramic film. Materials and Methods : The bone mineral density values of lumbar and femur were measured by dual-energy X-ray absorptiometry(DEXA) and T scores of lumbar were obtained. T scores were classified into 3 group (T<-2.5, $-2.5{\leqq}T<-1$, $-1{\leqq}T$). Radiographic densities of alveolar bones were measured from interdental bones of premolar, molar areas in the maxilla and mandible and expressed into copper step wedge thickness by Scion $Image^{(R)}$ program. We considered these values of step wedge thickness as bone density of alveolar bone. Panorama mandibular index(PMI) was calculated by the method that the height of the inferior cortex of the mandible was divided by the height from the lower border of the mandible to the superior edge of the mental foramen. Bone density of alveolar bone and PMI were analysed statistically. Results : There were significant differences in bone mineral density of lumbar and femoral neck between control and experimental groups. There were also significant differences in bone density of premolar and molar area of jaw between control and experimental groups by MANOVA test. When considered lumbar T variables, there was only difference in interdental bone density of maxillary molar area between control and experimental group, but there was interaction. Interdental bone density of experimental group was appeared higher in $-1{\leqq}T$ group and lower in T<-2.5 group than control group. There was significant difference in PMI between control and experimental groups, but there was also inter action, thus, PMI of experimental group was appeared higher in $-1{\leqq}T$ group and lower in T<-2.5 group than control group. Conclusion : There were significant differences of alveolar density and cortical bone thickness between young men and post-menopausal women in periapical and panoramic film. These differences were dependent on lumbar T.