• The KIPS Transactions:PartC
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• v.12C no.2 s.98
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• pp.191-200
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• 2005

The brilliant achievements in computers and the internet technology make it easy for users to get useful information. But at the same time, the damages caused by intrusions and denial of service attacks are getting more worse. Specially because denial of service attacks by internet worm incapacitate computers and networks, we should draw up a disposal plan against it. So far many rule-based intrusion detection systems have been developed, but these have the limits of these ability to detect new internet worms. In this paper, we propose a system to detect intrusion and generate detection rule against scan-based internet worm, paying attention to the fact that internet worms scan network to infect hosts. The system detects internet worms using detection rule. And if it detects traffic causing by a new scan-based internet worm, it generates new detection nile using traffic information that is gathered. Therefore it can response to new internet worms early. Because the system gathers packet payload, when it is being necessary only, it can reduce system's overhead and disk space that is required.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.17 no.1
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• pp.57-66
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• 2007

Scanning worms increase network traffic load because they randomly scan network addresses to find hosts that are susceptible to infection. Since propagation speed is faster than human reaction, scanning worms cause severe network congestion. So we need to build an early detection system which can automatically detect and quarantine such attacks. We propose algorithms to detect scanning worms using network traffic characteristics such as variance, variance to mean ratio(VMR) and correlation coefficient. The proposed algorithm have been verified by computer simulation. Compared to existing algorithm, the proposed algorithm not only reduced computational complexity but also improved detection accuracy.

• Journal of agricultural medicine and community health
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• v.16 no.1
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• pp.61-69
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• 1991

Serodiagnosis of Clonorchis sinensis infections will probably be a first choice tool for screening of clonorchiasis in a future because of increasing difficulties in collection and examination of stools. The sensitive test such as ELISA can he used effectively. However there are some limitations in serological diagnosis for the detection of serum antibody. One of the major problems is the non-specificity of the antigens which produce cross reaction with other helminthic infection sera. To solve this problem. many investigators have tried to purify the antigens used. In this study, we determined the antigenic profile of the crude saline extract antigen of C. sinensis at early developmental stage based on SDS-PAGE and immunoblotting techniques for the purpose of understanding the nature of C. sinensis worm antigen The following results were obtained : 1) The SDS-PAGE showed many protein hands ranging from 10Kd to 91Kd relative molecular weight. Among them, 66, 46, 40, 33, 27, 24, 16, 14 and 10Kd bands were observed as a principle bands. The protein components of C. sinensis changed chronologically during their early developmental period. 44Kd band was stained unclearly in antigen of 2 weeks worm, but changed to concentrated state in antigen of 5 weeks worm. 35Kd band was found in antigen of 2 weeks worm, however this band was disappeared in antigen of 5 weeks worm. 22Kd band also lost its staining property gradually. 2) In spite of differences in antigenic profile, there was no differences in the data obtained by microplate ELISA using each antigen preparation. Absorbance value began to rise in between 2 to 3 weeks after infection. 3) By EITB. serum antibody recognized major protein bands with molecular weight of 91, 85, 63, 46, 40, 33, 24, 14 and 10Kd hand respectively. Among them 66, 33, 17 and 14Kd bands were observed as non-specific band because they reacted even in normal control sera. Generally, gradual increase of positive reactions were observed as the infection period of C. sinensis was prolonged. In other hand, the reaction of 10Kd hand did not occurred when 26th week sera was tested. 4) The positive reactions using antigens of 2 weeks worm, especially on 40 and 24Kd bands, were most strong and sharply demarcated compared to those of 3~5 weeks worm antigen.

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2009.04a
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• pp.137-150
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• 2009

Background: Heart failure can develop secondary to various heart diseases (e.g. mitral valvular insufficiency, congenital heart defects, heart worm infection). The clinical signs of heart failure can be confused with those of other conditions, such as respiratory disease. Therefore, specific, sensitive, rapid and inexpensive blood tests for heart failure are desirable. Cardiac troponins, natriuretic peptides and cytokines have been more recently used as indicators of heart disease in humans and animals. These peptides are sensitive to changes in vasoconstriction and dilation within the heart and are used for the diagnosis and prognosis of heart failure. Methods: Previously developed and newly developed cardiac biomarkers will be discussed for understating clinical implications and diagnostic values in heart diseases in small animals