• Journal of the Microelectronics and Packaging Society
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• v.27 no.3
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• pp.83-88
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• 2020

The evolution of smartphones has led to numerous researches in the mechanical behavior of flexible devices. Due to the nano-size of the thin flexible film, nanoindentation is widely used to evaluate its mechanical behaviors, such as elastic modulus, and hardness. However, the commonly used Oliver-Pharr method is not suited for analyzing the indentation force-depth curves of hard films on soft substrates, as the effects of soft substrate is not considered theoretically. In this study, the elastic modulus of the thin film was evaluated with references to other reported models which include the substrate effect, and with calibration of the indentation depth for the pile-ups between the indenter and test surface. We fabricated test samples by deposition of amorphous metal film on polyimide and silicon wafers for verification of modified models.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39B no.12
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• pp.842-855
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• 2014

Recently, the progress of smart phone market has retarded by oversupply therefore wearable computer has been the focus of new growth engine. Wearable computing system is a complex fusion of a variety of technologies such as wireless network, embedded, sensor and new material. Because these technologies involves utilization and mobility in addition to quality characteristic in existing software, application of ISO/IEC 9126 is not perfect when assessing quality of wearable computer. In this study, author suggested new quality assessment model for wearable computer by sorting quality attribute in ISO/IEC 9126 and adding new quality attribute. For this, author investigated features and functional requirements related to wearable computer. and then author suggested quality standard and metrics by identifying quality characteristic. Author confirmed practicality of quality assessment model by using suggested model in scenario and comparing quality assessment of three goods such as company S, L, G. This quality assessment model is expected to use guidelines for assessing quality of wearable computer.

• The Journal of Internal Korean Medicine
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• v.25 no.3
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• pp.582-589
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• 2004

This is a study of an admissional patient whose chief complaints were weakness and numbness in both legs, and lumbago. Diagnosis and treatment was based on overall analysis of symptoms from the point of view of muscular flaccidity due to damp-heat from an Oriental Medical point of view. 淸燥湯(Cheong Jo Tang) was administered against heat and dampness. Improvement was observed. For lack of objective criteria to evaluate improvement of these symptoms more case studies of this kind, done with screening tests and proper treatment through clinical application of the thinking of Oriental Medicine, will be needed.

• Archives of Pharmacal Research
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• v.26 no.11
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• pp.943-950
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• 2003

In the present studies, the acute toxic effects of 2-bromopropane (2-BP) and its analog, 1,2-dibromopropane (1,2-DBP), were investigated in female BALB/c mice. The mice were treated orally with either 2-BP at 2000 and 4000 mg/kg or 1,2-DBP at 300 and 600 mg/kg. Four days before necropsy, the mice were immunized intraperitoneally with sheep red blood cells (SRBCs). 1,2-DBP reduced the weights of the spleen and thymus weights and decreased the number of splenic cells. In addition, treatment with 1,2-DBP suppressed the antibody response to SRBCs. Meanwhile, only the antibody response was significantly suppressed by treatment with 2-BP. In the subsequent studies, the time course effects of 2-BP and 1 ,2-DBP on the hepatotoxic parameters were compared in female BALB/c mice. When mice were treated orally with either one of these chemicals for 6, 12, 24 and 48 h, the activities of serum alanine aminotransferase and aspartate aminotransferase elevated significantly only with 1,2-DBP 24 h after the treatment. The hepatic content of glutathione was reduced by 1,2-DBP. Meanwhile, these parameters were increased by 2-BP. The present results suggest that 1,2-DBP in the Solvent 5200 also contributes to the immnunotoxicity, although 2-BP is a major component.

• The Bulletin of The Korean Astronomical Society
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• v.35 no.1
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• pp.84.1-84.1
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• 2010

2009 세계 천문의 해(International Year of Astronomy 2009, IYA2009) 한국조직위원회는 지난 1년간 148개 참가국의 일원으로 다양한 활동을 펼쳤다. IYA2009 활동은 강연, 별 축제와 같은 고전적인 이벤트로부터 시, 수필, 에세이, 음악, 미술, 만화, 영화, 대회, 인터넷 생중계, 플래시 동영상과 같이 새롭게 시도된 프로그램에 이르기까지 다양하게 기획, 운영되었다. 또한 우리는 시민천문대와 과학관, 미술관은 물론, 지하철, 기차역, 시청, 놀이공원, 쇼핑몰, 백화점, 병원, 그리고 경찰서에 이르기까지, 기존의 전통적인 전시공간을 벗어나 다양한 장소에서 전시회와 동영상 상영을 시도했다. 우리는 지난 1년간 90여 종의 행사를 410여 회에 걸쳐 진행했으며, 총 11,700,000여 명의 일반 시민과 학생들이 2009 세계 천문의 해에 참여한 것으로 추산하고 있다. IYA2009는 강연 200여 회, 전시 80여 회, 공연 15회, 학회 7회 등으로 요약할 수 있으며, 공식책자 4종, 도록 3종이 발간되었다. 관련 보도자료는 40 차례 배포했으며, 그 결과 2,500여 건이 언론을 통해 보도되었고, 총 248편의 연재기사가 실렸다. 2009 세계 천문의 해 한국조직위원회 공식 웹진 '이야진' 접속자는 999,890명, 총 페이지 뷰 건수는 131,963,473을 기록했다.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.1
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• pp.279-284
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• 2004

Excluding an operation remedy about an example of Traumatic Cervical Stenosis patient, by doing pattern identification such as blood stagnation in hospitalization for the early days and such as the stagnation of Oi for the middle days and such as Eum deficiency of liver and kidney for the last. We have done treatment by being based on method of therapy to promote blood flow to remove blood stasis and to promote the normal flow of Oi and to nourish the liver and the kidney. In result, we had remarkable conclusion and considered that we had to treat a patient like that appropriately by distinguishing & making a diagnosis correctly from now on. If we apply clinically by thinking of Oriental Medicine through more example of symptoms, we have considered that it will serve as a momentum that we can sympathize with the excellency of Oriental Medicine. In the future, we have considered that have to be necessary to make more researches and reports upon it.

• The Journal of Internal Korean Medicine
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• v.26 no.1
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• pp.252-264
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• 2005

This concerns three patients diagnosed as lateral medullary infarction from cerebral infarction of the brain stem and hospitalized. They were diagnosed and treated for 手足??(paralysis of extremities), 痺症(bi syndrome), 麻木(numbness), 不仁(akinesia), 眩暈(Vertigo) through Oriental Medicine. Improvement in both sense disorder and motor disorder was seen and is therefore reported here. To detect symptoms of a brain stem disorder clinically, pathological symptoms must be isolated and the patient must be screened through radiological and neorological examination. If this is properly and carefully done from the first stage, and according to this diagnosis, with the cycle of the disease considered, a treatment plan can be laid. Modem Medicine offers easy diagnosis for cerebro-vascular disease, but the treatment is less effective than that offered by Oriental Medicine. This report is given with a plea for further research and more reportage of clinical cases of cerebro-vascular disease treated through Oriental Medicine.

• The Korean Journal of Malacology
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• v.27 no.1
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• pp.77-86
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• 2011

The unwanted artificial oil-spill has severely contaminated the coastal environment in the world. Level of contamination has so far been monitered by various indicator species including mussel, oysters, flounder, and cockle. In this study, we decided to use the oyster as a model organism to observe the morphological changes being exposed to the artificial oil-spill in the coastal areas in Taean, Korea. The oysters were collected from four local sites (Sindu-ri, Uiwang-ri, Jonghyeon-dong, Ansan and Uihang-ri) exposed to various levels of pollution after an oil spill in Taean. Microscopic analysis of the hepatopancreatic microstructure in the digestive gland from the collected oysters show that the swelling, whorl, and destruction phenomenon of the nuclear membrane, a well-known microstructure induced by heavy metal exposure, was observed. Nuclear body (Nb), another typical characteristic of contamination or infection were also observed in some samples. Necrosis was observed in tissue samples collected from the area with a high degree of oil pollution. In addition, parasite-like particles (virus, perkinsus) were observed in most samples. Taken together, these results suggest that oil contamination in the oyster habitats influences the cytopathological changes in Crassostrea gigas.

• Bulletin of the Korean Chemical Society
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• v.31 no.11
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• pp.3309-3312
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• 2010

D-[$^{18}F$]FMAU and L-[$^{18}F$]FMAU are F-18 labeled nucleoside analogue which have been efficiently synthesized in order to be a PET imaging probe. D-[$^{18}F$]FMAU and L-[$^{18}F$]FMAU were compared as PET imaging agents using HSV1-TK gene expressing tumor-bearing mice. Their cellular uptake profiles were also compared using MCA and MCA-TK cell lines. D-[$^{18}F$]FMAU demonstrated higher cellular uptake and higher accumulation in MCA-TK tumor regions than L-[$^{18}F$]FMAU. On the other hand, L-[$^{18}F$]FMAU showed higher MCA-TK/MCA ratio of %ID/g than that of D-[$^{18}F$]FMAU. L-[$^{18}F$]FMAU can be utilized as a good candidate for HSV1-TK PET imaging. It can be used for antiviral drug evaluation.

• International Journal of Oral Biology
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• v.42 no.4
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• pp.203-211
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• 2017

The aim of this study was to evaluate the role of demineralized and particulate autogenous tooth, and interleukin-6 in bone regeneration. A demineralized and particulate autogenous tooth was prepared and human osteoblast-like cells (MG63) and human osteosarcoma cells were inoculated into the culture. The rate of cell adhesion, proliferation and mineralization were examined, and the appearance of cellular attachment was observed. An 8 mm critical size defect was created in the cranium of rabbits. Nine rabbits were divided into three groups including: An experimental group A (3 rabbits), in which a demineralised and particulate autogenous tooth was grafted; an experimental group B (3 rabbits), in which a demineralized, particulate autogenous tooth was grafted in addition to interleukin-6 (20 ng/mL); and a control group. The rabbits were sacrificed at 1, 2, 4 and 6 weeks for histopathological examination with H-E and Masson's Trichrome, and immunohistochemistry with osteocalcin. The cell-based assay showed a higher rate of cell adhesion, mineralization and cellular attachment in the experimental group A compared with the control group. The animal study revealed an increased number of osteoclasts, newly formed and mature bones in the experimental group A compared with the control group. Eventually, a higher number of osteoclasts were observed in the experimental group B. However, the emergence of newly formed and mature bone was lower than in the experimental group A. The current results suggest that treatment with demineralized and particulate autogenous tooth and interleukin-6 is not effective in stimulating bone regeneration during the bone grafting procedure.