• 대한통합의학회지
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• 제10권4호
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• pp.83-91
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• 2022

Purpose: The goal of this study was to investigate changes in dual-task performance according to age and difficulty of cognitive tasks for the in community-dwelling elderly populations, as well as to examine their changes in hand dexterity according to age and cognitive function. Methods: A total of 135 people aged 65 years old and over participated in the study. To evaluate each participant's dual-task performance, each participant completed a dual task. To assess their cognitive function, the Korean Mini-Mental State Examination (MMSE-K) and the Korean version of Montreal Cognitive Assessment (MoCA-K) were the tools used. Participants were divided into three groups based on their age: 65-69 years, 70-79 years, and 80-89 years. Results: The findings showed that age groups and the difficulty of the cognitive task significantly affected the amount of time required for dual-task performance (p<.001). Additionally, the dual-task correct response rate (CRR) decreased significantly with age groups and the difficulty of the cognitive task (p<.001). The amount of time required for finger dexterity performance increased significantly with age groups (mean score±standard deviation [SD]; 19.46±2.26 in subjects aged 65-69 years; 21.92±2.61 in subjects aged 70-79 years; and 23.82±2.92 in subjects aged 80-89 years; p<.001). Moreover, as a result of the correlation between hand dexterity and cognitive function, MoCA-K was -0.563 and MMSE-K was -.412, showing a statistically significant correlation (p<.001). Conclusions: Age and the difficulty of the cognitive task affect the community-dwelling elderly populations in terms of dual-task performance and dual-task CRR. In addition, aging and general cognition have an impact on hand dexterity. Based on the results of this study, it is anticipated that the results will serve as a reference for domestic clinical trials that confirm cognitive decline in the elderly using dual task and hand dexterity evaluation.

• Nutritional Sciences
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• 제7권4호
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• pp.189-195
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• 2004

1bis study investigated the antioxidative effect in kidney of senescence-accelerated prone SAMP8 mice with calorie restriction. 4-weeks-old SAMP8 female mice were divided into 4 groups according to the experimental feeding period: for 4, 8, 12 month, and at natural death. Each group was subdivided into 2 groups, with thirteen mice each one, as ad libitum group and as dietary restriction group (60% of ad libitum feeding amount). After feeding for a given period, the mice were sacrificed to get the following results: among the experimental groups, there wereno significant differences in xanthine oxidase (XOD) activity in their kidney tissues. The contents of cytochrome $P_{450}$ decreased in ad libitum group and dietary restriction group by age. The activity of NADPH-cytochrome $P_{450}$ reductase showed a trend similar to cytochrome $P_{450}$. Superoxide radical content increased with age. At the 4th, 8th and 12 months of the experimental period, the activity in the dietary restriction group was less than that of ad libitum group by as much as 17% 14% and 14% respectively. For hydrogen peroxide, the contents were increased in the ad libitum group with age, while no correlation between content and age was observed in the dietary restriction group. In the 8th and 12th months of the experimental period, the were in the dietary restriction group less than that of ad libitum group counterpart as much as 17% and 20o/c, respectively. For the cellular membrane stability of the kidney, no significant correlation with age was observed in either the dietary restriction group or the ad libitum group. However at the 12th month of the experiment, however, the stability in the dietary restriction group was 11 % higher than that in the ad libitum group. In conclusion, with these results obtained from the SAMP8 mouse model, we demonstrate that dietary restriction has the effects of anti-oxidation and anti-senescence in the kidney.

• 보험의학회지
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• 제4권1호
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• pp.110-132
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• 1987

A study on hepatomegaly detected by abdominal palpation, and facial telangiectasia in a total of 3,418 insured persons medically examined at the Honam Medical Room of Dong Bang Life Insurance Company Ltd. from February, 1984 to August, 1985 was undertaken. The results were as follows: 1) Hepatomegaly was found in 383 cases(27.5%) among the 1,395 insureds of male and in 163 cases(8.1%) among the 2,023 insureds of female. The difference of incidence of hepatomegaly between all males and females showed statistical significance(p<0.001). In each age group, the incidence of hepatomegaly in :nale was higher than that in female. The incidence of hepatomegaly in each age group in male increased cnosiderably with age; it showed 11.6%,16.2%, 42.6% and 52.9% from second to sixth decade in order, thereafter in seventh decade it decreased to 26.7%, While the incidence of hepatomegaly in female increased slightly in each age group. 2) Facial telangiectasia was found in 318 cases(22.8%) among all males and in 157 cases(7.8%) among all females. The difference of incidence of telangiectasia between all males and females showed statistical significance(p<0.001). In each age group, the incidence of telangiectasia in male was higher than that in female, except of second decade. The incidence of facial telangiectasia in each age group in male increased considerably with age; while it increased slightly in female. 3) Facial telangiectasia accompanied by hepatomegaly was found in 235 cases(61.4%) among 383 cases of hepatomegaly in male and in 69 cases(42.3%) among 163 cases of hepatomegaly in female. The difference of incidence of telangiectasia between males and females show ed statistical significance(p<0.001). 4) Facial telangiectasia without spider angiomata accompanied by hepatomegaly was found in 201 cases(52.5%) among 383 cases of hepatomegaly in all males and in 67 casgs(41.4%) among 163 cases of hepatomegaly in all females; facial spider angiomata accompanied by hepatomegaly was found in 34 cases(8.9%) among 383 cases of hepatomegaly in all males and in 2 cases(1.2%) among 163 cases of hepatomegaly in all females. 5) Abnormal SGOT activity was found in 19 cases(7.9%) among 242 cases of hepatomegaly in all males and in one case(1.5%) among 67 cases of hepatomegaly in all females. The difference of incidence of abnormal SGOT activity showed statistical significance(p<0.001). The incidence of abnormal SGOT activity by the size of hepatomegaly, that is, palpated <1 finger's breadth, <2 fingers' breadth and ${\geqq}2$ fingers' breadth, revealed 2.2%, 6.0% and 60.0% respectively in all males, while abnormal SGOT activity was found only one case in fifth decade among 67 cases of hepatomegaly in all females. 6) In ordinary medical examination(the insured amount is low) abnormal SGOT activity was found in 7 cases(4.8%) among 146 cases of hepatomegaly palpated $1\frac{1}{2}$ fingers' breadth and under, while it was not found in 37 cases of the same sized hepatomegaly in all females. Above mentioned 7 cases are thought to be very significant because 7 cases occupy 35% in 20 cases of abnormal SGOT activity with hepatomegaly. 7) Abnormal SGOT activity was found in 12 cases(4.4%) among 273 cases of hepatomegaly of "not firm" consistency, while it was found in 8 cases(22.2%) among 36 cases of hepatomegaly of "firm" consistency. The difference of incidence of abnormal SGOT activity showed statistical significance(p<0.05). 8) Abnormal SGOT activity was found in 5 cases(17.9%) among 28 cases of spider angiomata with hepatomegaly, while it was found in 10 cases(7.3%) among 166 cases of telangiectasia without spider angiomata with hepatomegaly. Owing to a small number of cases, statistical significance was not recognized, but the incidence of abnormal SGOT activity in spider angiomata cases with hepatomegaly is apt to be higher than that in telangiectasia cases without spider angiomata with hepatomegaly. 9) The incidence of abnormal SGOT activity is apt to be higher with age in male group; abnormal SGOT activity was not found among 4 cases of hepatomegaly in second decade and it was 3.8% in third decade, 4.5% in fourth decade, 9.3% in fifth decade, 17.5% in sixth decade and 33.3% in seventh decade, while the incidence of it was only one case among 67 cases in all females. 10) It is believed that the performance of liver function test to the subjects with hepatomegaly even in ordinary medical examination(the insured amount is low) will give considerable contribution for medical selection of hepatomegaly risk. 11) Age of the insured(young or old), presence of facial telangiectasia or spider angiomata especially and their severity, and consistency of enlarged liver(firm or not) should be considered to increase accuracy in evaluating hepatomegaly risk.

• 대한임상검사과학회지
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• 제41권3호
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• pp.135-139
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• 2009

Pulmonary function test has been know to be greatly affected by body indices, such as sex, age, height, body weight, body surface area (BSA) and body mass index (BMI), so hat this study was focused to see the relationship between body index and flow-volume curves. Subjects were 156 (male 90, female 66) and they were examined for pulmonary function test in terms of body index and correlation/multiple regression analysis of flow-volume curves at Presbyterian Medical Center from March to August, 2009. The followings results after analyzing the correlation between body index and flow-volume curves. Although flow-volume curve FEF25-75% showed close correlation with age, body weight, and body surface area, but not with body mass index. In addition, multiple regression analysis was performed to see how each body index affects flow-volume curve FEF25-75%, and FEF25-75% dispersion was explained as 74.5% with age only, 94.2% with age and height, and 96% with age, height, and sex. Therefore, sex, age and height that are mainly used for predictive formular of pulmonary function test and nomogram were important factors for pulmonary function test itself, and further study must be done for other body index.

• Korean Journal of Radiology
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• 제22권7호
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• pp.1194-1202
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• 2021

Objective: To investigate the age-dependent changes in regional cerebral blood flow (CBF) in healthy adults by fitting mathematical models to imaging data. Materials and Methods: In this prospective study, 90 healthy adults underwent pseudo-continuous arterial spin labeling imaging of the brain. Regional CBF values were extracted from the arterial spin labeling images of each subject. Multivariable regression with the Akaike information criterion, link test, and F test (Ramsey's regression equation specification error test) was performed for 7 models in every brain region to determine the best mathematical model for fitting the relationship between CBF and age. Results: Of all 87 brain regions, 68 brain regions were best fitted by cubic models, 9 brain regions were best fitted by quadratic models, and 10 brain regions were best fitted by linear models. In most brain regions (global gray matter and the other 65 brain regions), CBF decreased nonlinearly with aging, and the rate of CBF reduction decreased with aging, gradually approaching 0 after approximately 60. CBF in some regions of the frontal, parietal, and occipital lobes increased nonlinearly with aging before age 30, approximately, and decreased nonlinearly with aging for the rest of life. Conclusion: In adults, the age-related perfusion patterns in most brain regions were best fitted by the cubic models, and age-dependent CBF changes were nonlinear.

• 대한치과교정학회지
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• 제26권4호
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• pp.373-387
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• 1996

본 연구는 비인두와 adenoid의 성장발육 양상을 조사하여 부정교합자의 진단에 있어 비호흡 기능 평가시 유용한 기준을 얻기 위하여 시행되었다. 남자 19명, 여자 14명, 총 33명의 정상 교합자를 대상으로 8.5세부터 18.5세까지 촬영된 10년간의 누년적 측모 두부 X선 규격사진을 연구 자료로 비인두와 adenoid 부위의 거리와 면적 및 상대적 기도 비율을 계측 분석하여 다음과 같은 결론을 얻었다. 1. 각 연령(8.5세-18.5세)에서 남녀별 각 계측항목의 평균과 표준 편차를 얻었다. 2. 비인두의 height와 depth는 남자에서 14.5세까지, 여자에서 12.5세까지 성장하였다.(p<0.05). 3. 비기도의 상대적 면적은 8.5세에 최소치를 나타내었고 남자는 10.5세부터 12.5세 사이에, 여자는 12.5세부터 14.5세 사이에 유의한 증가를 나타내었다(p<0.05). 4. 비기도의 상대적 면적과 비기도 관련 계측항목 간의 상관분석에서 Ad2-PNS, Ad2-PNS/Ho'-PNS 및 Upper pharynx가 남녀 모두 전 연령구간에서 비기도의 상대적 면적과 상관성이 있었다 (p<0.01).

• 한국가금학회지
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• 제10권2호
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• pp.75-81
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• 1983

산란종계의 란중을 개량하기 위하여 란중에 대한 유전력과 유전상관등의 유전적 모수를 추정한 후 백색 레그혼종 2계통(A, K)에서 주령에 따른 란중의 증가양상을 살펴보았다 또한 선발에 의한 유전적 개량량을 크게 하기 위하여 조기선발을 실시할 경우 조기선발의 최적시기를 찾아내는 것이 중요하므로 년 평균란중에 대한 각 기간별 란중의 상관관계와 아울러 회귀관계를 분석하여 최적 선발시기를 알아보았고 각 기간별 선발에 의한 개량량을 상대적으로 나타내므로써 조기선발에 대한 타당성을 구명하고자 본 시험을 수행하였으며 얻어진 결과는 다음과 같다. 주령이 늘어남에 따라 란중도 증가하였는데 산란초기에서는 증가량이 컸지만 점차 감소하였으며 회귀방정식으로 나타낸 증가량은 A, K계통에서 주당 각각 0.46g과 0.83g이었다. 년 평균 란중에 대한 각 기간별 란중의 회귀계수는 29-32주령의 평균란중이 0.86(A), 0.88(K)로 나타나 가장 큰 수치를 보였다. 45-48주령의 평균란중을 기준으로 했을 때의 선발에 대한 각 기간 평균란중의 선발상대효율에서는 A계통에서 33-36주령, K통계에서 29-32주령의 추정치가 가장 크게 나타나서 이 시기에서의 조기선발에, 대한 타당성을 보여주었다.

• Journal of Nutrition and Health
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• 제20권4호
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• pp.281-288
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• 1987

In this study we have evaluated daily beverage intake of the inhabitants in Seoul by a 24 hrs. recall procedure from 1145 respondents between pre-school children to adults in the period of June-July 1985. Estimates of consumption were made for each of seven beverage groups and comparisons were made within age, sex and body weight. Significant differences existed for certain beverage in each category analyzed. Total Fluid intake was greater for male than female at all ages and tended to be lower in the older age group with adjustment for differences in body weight. Milk was the major beverage among children while soft drinks were the predominant beverage for teen-ages. Alcoholic drinks represented the smallest component of daily fluid intake among women but were the second largest component of daily fluid levels for men over the age of 24 years.

• 대한가정학회지
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• 제43권1호
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• pp.69-84
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• 2005

The purposes of this study were to investigate (1) intention perspective taking, (2) cognitive cuing according to infant age, cue type, and emotional-situation fit, and (3) the relationship between a child's intention perspective taking and cognitive cuing. The subjects were 2 groups of 41 infants each aged 3- and S-years-old from two different day-care centers in Seoul and Kyonggi province. Each child was individually interviewed with pictorial tasks. There were significant differences in the children's intention perspective taking according to their age, type of intention, and intention-outcome fit. There were also significant differences in the children's cognitive cuing according to their age, cue type, and emotional-situation fit. A relationship between the intention perspective taking and cognitive cuing was also revealed that is, the thinking and application responses of cognitive cuing were positively related to the children's intention perspective taking.

• 한국멀티미디어학회논문지
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• 제25권1호
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• pp.39-51
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• 2022

Image-based gender classification and age estimation of human are classic problems in computer vision. Most of researches in this field focus just only one task of either gender classification or age estimation and most of the reported methods for each task focus on accuracy performance and are not computationally light. Thus, running both tasks together simultaneously on low cost mobile or embedded systems with limited cpu processing speed and memory capacity are practically prohibited. In this paper, we propose a novel light-weight gender classification and age estimation method based on ensemble multitasking deep learning with light-weight processing neural network architecture, which processes both gender classification and age estimation simultaneously and in real-time even for embedded systems. Through experiments over various well-known datasets, it is shown that the proposed method performs comparably to the state-of-the-art gender classification and/or age estimation methods with respect to accuracy and runs fast enough (average 14fps) on a Jestson Nano embedded board.