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Tuberculous Aortitis with Aorto-bronchial Fistula (대동맥-기관지루를 동반한 결핵성 대동맥염)

  • Wi, Jin-Hong;Han, Il-Yong;Yoon, Young-Chul;Lee, Yang-Haeng;Hwang, Youn-Ho;Cho, Kwang-Hyun
    • Journal of Chest Surgery
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    • v.41 no.2
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    • pp.277-280
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    • 2008
  • Tuberculous aortitis is a very rare disease. Furthermore, it is all the more rare for it to be complicated by the development of an aortic aneurysm or the formation of aorto-bronchial fistula. If it is complicated by rupture of the aorta, mortality is very high. If the patient didn't contract tuberculosis, but was expectorating blood, we would have to carry out a chest CT promptly, in order to make a rapid and accurate diagnosis of this disease. A 46-year-old male patient was admitted due to the sudden onset of intermittent hemoptysis and chest discomfort. CT scans of the chest showed an aneurysmal change to the descending thoracic aorta, and the formation of an aorto-bronchial fistula, which originated from this aneurysm and communicated with its left lower lobe. We operated with an artificial vessel graft interposition of the descending thoracic aorta and a left lower lobectomy. Because the diagnosis was of tuberculosis, we started anti-Tbc medication and long term anti-Tbc medication was recommended.

A Study on Ceramic Restoration Methods with Full Color 3D Printing (풀 컬러 3D 프린팅을 이용한 도자기 복원 방법 연구)

  • Shin, Woo Cheol;Wi, Koang Chul
    • Journal of Conservation Science
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    • v.36 no.5
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    • pp.306-314
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    • 2020
  • The use of synthetic resins in ceramic restoration poses several challenges, including aging and potential damage to artifacts, which has raised the need to investigate new materials and restoration methods. This study set out to incorporate full color 3D printing into the 3D digital technology-based restoration method, an emerging approach currently being researched, and to print out missing parts with color information. After examining material physical properties with an experiment, the investigator printed out missing parts from a white porcelain vessel and grayish-blue-powdered celadon plate and compared them in chromaticity and brilliance. The experimental results show that the outputs had comparable tensile strength to the original restoration materials, whereas the recorded compressive strength was approximately 1.4~2 times higher than that of the original restoration materials. According to the NIST table of color difference values, the white porcelain vessel was visible at ΔE*ab 1.55, and the grayish-blue-powdered celadon plate was perceivable at 3.34. Even though it was impossible to express the colors accurately owing to printer limitations, this non-contact approach reduced the possibility of damage to the minimum. In conclusion, it can be applied to objects with a high chance of damage or generate display effects through purposeful color differentiation in missing parts.

Length-weight Relation and von Bertalanffy's Growth Model of Zacco koreanus Population Distributed in the Tributaries of the Nakdong River (낙동강 지류에 분포하는 참갈겨니 개체군의 전장과 체중 관계 및 von Bertalanffy의 성장모델)

  • Choi, Eui-Yong;Choi, Jae-Seok;Seo, Jin-Won
    • Korean Journal of Ecology and Environment
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    • v.39 no.2 s.116
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    • pp.226-235
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    • 2006
  • Populations of Zacco koreanus, distributed in four different tributaries of mid-upper reach Nakdong River were investigated to analyze a length-weight relation and von Bertalanffy's growth model. Fish sampling was conducted by common method (cast net and kick net) during March to October 2005. Fishes caught in the field were identified immediately, and then individuals of Zacco koreanus were preserved in 10% formalin to further measure their total length and weight in the laboratory. As the results of the equation based on length-weight relation, values of parameter b on the population of all tributaries were greater than 3.0 and the value on Bohyeon Stream was the maximum (3.26), indicating that the fish in the stream became more rotund as the length increases. In the mean time, we examined Brody growth constant (k) induced by the von Bertalanffy's growth model, and we found more steady state population in Wi (-0.18) and Byeongbo (-0.21) Streams than in fan (-0.38) and Bohyeon (-0.37) Streams. The findings would be used to assess local water environment on tributaries of the Nakdong River with understanding of ecological characteristics on the population of Zacco koreanus, as well as provide us fundamental information on domestic study of fish ecology.

The effects of economy education through MMORPG (온라인 게임을 통한 아동 경제 학습 효과 분석)

  • Wi, John-H.;Oh, Na-Ra;Kim, Yang-Eun
    • Journal of Korea Game Society
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    • v.5 no.4
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    • pp.13-22
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    • 2005
  • The research is a study on the effects of MMORPG (Massively Multi-player Online Role Playing Game) utilized in educational program. We investigated the possibilities of online game as an educational tool, especially in the field of economy education. Students have been taught market, price, profit, scarcity of goods etc., and then they played an online game we provided. Students manufactured cyber goods and also sold or bought various materials to maximize their profits. A experimental group was compared with a control group on measures of economic self-efficacy, motivation for economic learning, and attitude for economic learning, economic self-efficacy and motivation for economic leaning scales consist of 2 factors and attitude for economic leaning consists of 1 factor. Participants were 5th grade elementary school students(experimental group: 154, control group: 158). After the experiment, students' self-efficacy and motivations for economy learning have increased significantly. It has been found that students understand more easily the difficult economic terms such as' inflation', 'price setting', 'scarcity of goods etc. Their motivations for economy learning also increased significantly. This result indicates that online games have the potentiality that can be utilized as an educational tool.

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The Comparison of Tannins and Nutritional Components in the Acorn of Major Oak Trees in Korea (한국의 주요 참나무류 종실의 탄닌 및 영양성분 비교)

  • Lee, Wi Young;Na, Sung June;Park, Eung-Jun;Han, Sang Urk
    • Korean Journal of Plant Resources
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    • v.27 no.4
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    • pp.279-285
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    • 2014
  • Nutritional composition, including total phenolics, tannins and nutrient components, of acorns of Q. actissima, Q. serrata, Q. variabilis and Q. mongolica were analyzed. Acorns were collected from each tree species, which were grown in a seed orchard. Contents of both total phenolics and tannins in acorns of Q. serrata were higher than those of Q. actissima (p<0.05). Interestingly, Q. serrata contained the highest amount of water soluble tannins (71 mg/g dw) and the lowest levels of water insoluble tannins (8.1 mg/g dw) among 4 oak species, resulting that acorns of Q. serrata had the lowest proportion of insoluble tannins. Among 4 oak species tested, Q. mongolicav acorns contained the highest levels of both total dietary fiber (TDF) and ascorbic acid, while the content of beta-carotene in Q. mongolicav was 52-fold lower than that in Q. variabilis ($520{\mu}g/100g$). Our result showed that nutritional composition of acoms was significantly different between oak species, indicating that tastes or nutritional values might be different as well among major oak species in Korea.

Restoration of Earthenware & Porcelain Cultural Assets using 3D Printing (3D 프린팅을 이용한 토기·자기 문화재 복원 연구)

  • Lee, Hae Soon;Wi, Koang Chul
    • Journal of Conservation Science
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    • v.31 no.2
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    • pp.131-145
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    • 2015
  • Cultural assets restoration is being considered highly as a practical way to extend the lifespan of damaged cultural assets and re-highlight their value. However, restoration process has been mostly dependent on the manual work involving the experience and skill of a person performing restoration, thereby requiring much time and effort. In recent, it became possible to apply a method allowing restoration to be performed more accurately and easily according to the material characteristics and shape of cultural assets. Namely, it is to use a method of printing out the 3D shape data computed in computer as real object by using 3D printer for the restoration that has been performed manually. The missing part of a cultural asset is computed into computer data first and is printed out by using 3D printer to undergo a simple shaping process. The result of 3D printer application showed that repetitive output and shape and figure revision of digital data were possible, and it was possible to improve the degree of completedness of restoration through test output using various types of restoration materials using various materials. For the purpose of verifying the possibility of applying 3D printer to restore missing part of earthenware, two pieces of modern reproductions, namely, the Seven Treasure Incense Burner and Earthenware with Wagon Wheel Decoration, were artificially damaged. The restoration result showed that compared to manual work, it showed better effectiveness in curtailing work time and reproducing accurate shape. On the other hand, secondary manual work was slightly needed for detailed binding and to vividly express surface texture.

Study on the Property and Applicability of the Bisphenol-A Type Epoxy Putty According to the Mix of Filler (개발된 Bisphenol-A계 Epoxy Putty의 충전제 배합에 따른 물성 및 적용성에 관한 연구)

  • Wi, Koang-Chul;Oh, Seung-Jun
    • Journal of Conservation Science
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    • v.32 no.4
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    • pp.459-469
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    • 2016
  • The goal of this study was to examine property changes induced by the choice of filler used with an epoxy resin that was developed in 2014 to restore cultural assets and consider the applicability of the resin as a restorative agent. The properties of putty mixed with 9 types of fillers and as-developed resins were compared with those of existing materials with regard to stability, superiority and applicability. The potential of the putty as an alternative material was also examined. The materials produced the best adhesiveness, color change and hardness results when mixed with lime. Micro balloon produced the best wear rates and hardening times, while diatomite produced the best tensile and compressive strengths. A plaster and white mineral pigment mixture produced the best specific gravity. Every material except for lime exhibited about 2.5-20 times higher wear rates than the existing material, which is thought to exhibit an excellent cutting force. The hardening time was enhanced by about 0.5-9 times to improve convenience. The stability of the relic was also ensured by improving hand staining without any shrinkage or deformation. The material exhibited about 0.5-27 times less yellowing. Thus, it is thought to be a material that can reduce property changes and reduce the degree of relic fatigue which occurs during reprocessing and sense of difference from relic.

Generation and Characterization of a Neutralizing Human Monoclonal Antibody to Hepatitis B Virus PreS1 from a Phage-Displayed Human Synthetic Fab Library

  • Jo, Gyunghee;Jeong, Mun Sik;Wi, Jimin;Kim, Doo Hyun;Kim, Sangkyu;Kim, Dain;Yoon, Jun-Yeol;Chae, Heesu;Kim, Kyun-Hwan;Hong, Hyo Jeong
    • Journal of Microbiology and Biotechnology
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    • v.28 no.8
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    • pp.1376-1383
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    • 2018
  • The hepatitis B virus (HBV) envelope contains small (S), middle (M), and large (L) proteins. PreS1 of the L protein contains a receptor-binding motif crucial for HBV infection. This motif is highly conserved among 10 HBV genotypes (A-J), making it a potential target for the prevention of HBV infection. In this study, we successfully generated a neutralizing human monoclonal antibody (mAb), 1A8 (IgG1), that recognizes the receptor-binding motif of preS1 using a phage-displayed human synthetic Fab library. Analysis of the antigen-binding activity of 1A8 for different genotypes indicated that it can specifically bind to the preS1 of major HBV genotypes (A-D). Based on Bio-Layer interferometry, the affinity ($K_D$) of 1A8 for the preS1 of genotype C was 3.55 nM. 1A8 immunoprecipitated the hepatitis B virions of genotypes C and D. In an in vitro neutralization assay using HepG2 cells overexpressing the cellular receptor sodium taurocholate cotransporting polypeptide, 1A8 effectively neutralized HBV infection with genotype D. Taken together, the results suggest that 1A8 may neutralize the four HBV genotypes. Considering that genotypes A-D are most prevalent, 1A8 may be a neutralizing human mAb with promising potential in the prevention and treatment of HBV infection.

Study on the Development and Property of Epoxy Putty with Excellent Low Shrinkage and Cutting Force Using Mercaptan Type and Diamine Type (Mercaptan계와 Diamine계를 이용한 저수축·절삭력이 우수한 Epoxy Putty의 개발 및 물성에 관한 연구)

  • Oh, Seung-Jun;Wi, Koang-Chul
    • Journal of Adhesion and Interface
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    • v.16 no.4
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    • pp.137-145
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    • 2015
  • This study aimed to develop epoxy putty as a multi-purpose connection and restoration material that can be used for material-specific restoration work such as metal, wood, ceramics, earthenware and stone artifacts by replacing synthetic resins currently being used for preservation treatment of cultural assets. Existing synthetic resins have the issue of cutting force resulting from high strength, deflection resulting from long hardening time, contaminating the surface of artifacts through staining on tools or gloves and need for re-treatment resulting from material discoloration. Accordingly, paste type restoration material most widely being used in the field of cultural assets preservation treatment was selected and examined the property to select it as an object of comparison. Based on such process, epoxy putty was developed according to the kind of agent, hardener and filler. For the purpose of solving the issues of existing material and allowing the epoxy putty developed to have similar property, property experiments were conducted by selecting agents and hardeners with different characteristics and conditions. The study findings showed that both kinds are paste type that improved work convenience and deflection issue as a result of their work time of within 5~10 minutes that are about 3~10 times shorter than that of existing material. In regards to wear rate for increasing cutting force, it improved by about 3 times, thereby allowing easy molding. For the purpose of improving the issue of surface contamination that occurs during work process, talc and micro-ballon were added as filler to reduce the issue of stickiness and staining on hand. Furthermore, a multi-purpose restoration material with low shrinkage, low discoloration and high cutting force was developed with excellent coloring, lightweight and cutting force features.

Anti-obesity Effects of Sparassis crispa on High-fat Diet-induced Obese Mice (고지방식이로 유도한 비만 흰쥐에 대한 꽃송이 버섯의 항비만 효과)

  • Lee, Mi Ra;Hou, Jing Gang;Begum, Shahnaz;Wang, Yun Bo;Oh, Deuk Sil;Wi, An Jin;Yoon, Byung Sun;Sung, Chang Keun
    • Journal of Life Science
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    • v.24 no.9
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    • pp.952-958
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    • 2014
  • The present study investigated the anti-obesity effects of Sparassis crispa (SC) on mice fed a high-fat (HF, 45 kcal% fat) diet. Mice were fed either a normal control diet and an HF diet or an HF diet supplemented with SC (1%, 3%, and 5%) for 12 weeks. The consumption of an HF diet compared to the NC group resulted in increases in body weight, the food efficiency ratio (FER), retroperitoneal and subcutaneous fat weights, cholesterol and triglyceride levels, fecal fat, and liver lipids. However, the administration of SC significantly decreased body weight gain, food intake, FER, cholesterol and triglyceride levels, and liver lipids in a dose-dependent manner. In particular, treatment with 5% SC significantly reduced the occurrence of fatty liver deposits and steatosis, which are associated with the increased adipocyte size in mice fed an HF diet. Therefore, these results suggested that dietary supplementation with SC exerts anti-obesity effects and could be used as a functional food to control obesity.