• 한국식품영양과학회:학술대회논문집
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• 한국식품영양과학회 2004년도 Annual Meeting and International Symposium
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• pp.110-115
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• 2004

The immature fruits of Poncirus trifoliata L. or Ponciri fructus (PF), well known as 'Jisil' in Korea, have been used against allergic diseases for generations, and still occupy an important place in traditional Oriental medicine. Anti-allergic effects of this fruit have been investigated in a few experimental models. Immunoglobulin E (IgE) is the principal immunoglobulin involved in immediate hypersensitivities and chronic allergic diseases. The effect of an aqueous extract of PF on in vivo and in vitro IgE production was investigated. PF dose-dependently inhibited the active systemic anaphylaxis and serum IgE production induced by immunization with ovalbumin, Bordetelia pertussis toxin and aluminum hydroxide gel. PF strongly inhibited interleukin 4 (IL-4)-dependent IgE production by lipopolysaccharide-stimulated murine whole spleen cells. In the case of U266 human IgE-bearing B cells, Ponciri fructus also showed an inhibitory effect on the IgE production. On the other hand, mast cell hyperplasia can be causally related with chronic inflammation. Stem cell factor (SCF), the ligand of the c-kit protooncogene product, is a major regulator and ohernoattractant of mast cells. Ponciri fiuctus (1 mg/mL) significantly inhibited the SCF-induced migration of rat peritoneal mast cells (RPMCs). RPMCs exposed to SCF (50 ng/mL) resulted in a drastic shape change with a polarized morphology while the cells exposed to Ponciri fructus (1 mg/mL) remained resting, with little or no shape alteration. The drastic morphological alteration and distribution of polymerized actin were blocked by pretreatment with Ponciri fructus. In addition, Ponciri fructus inhibited both TNF-alpha and IL-6 secretion from RPMCs stimulated with SCF. These results suggest that Ponciri fructus has an anti-allergic activity by inhibition of IgE production from B cells. These findings also provide evidence that Ponciri fructu inhibits chemotactic response and inflammatory cytokines secretion to SCF in mast cells.

• 한국식생활문화학회지
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• 제13권4호
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• pp.339-362
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• 1998

Food goods traded between Korea and Japan during the first term of the Cho Sun era included Omija (fruit of the Maximowiczia chinensis), Jat (pine nuts), Insam (Jinseng), rice, and beans as exports ; and pepper, sugar, and medicinal stuffs as imports. The trade between Korea and Japan was a result of Japanese envoies' visiting. The official number of Japanese envoies who had exchanges with Koreans were two thousand people a year. Once the Japanese entered Korea, they did not need to pay for their living expenses for the length of their visit because the Cho Sun government bore the whole expense. The Cho Sun government gave formal receptions to them, which included daily meals as well as banquet style meals. The daily meals included Jo-ban (breakfast), Jo-seok-ban (breakfast and dinner), and Ju-jeom-sim (lunch). Meals were served four times a day. The banquet style meals included Sam-po-yeon (a banquet that was held in Sam-po), Kyong-joong-young-jeon-yeon (a farewell banquet, and a welcome banquet that was held in Seoul), Jyu-bong-bae (to offer a guest a drink by day), No-yeon (a banquet that was held on the street), Kwol-nae-yeon (a banquet that was held within the Royal Court). It also included Ye-jo-yeon (a banquet that was held in Ye-jo), and Myong-il-yeon (a banquet that was held on a national holiday). The banquet style meals were composed of Ceon-tack (to set a table for dinner), Sang-hwa (a flower that was put on the food), Kwan-hwa (to offer a flower when a banquet was held), Ju-5-jan (the fifth wine glass), Dae-seon (meat), and music.

• 한국식품과학회지
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• 제29권2호
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• pp.337-342
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• 1997

벌꿀발효주인 mead 와 melomel의 제조방법을 비교하기 위하여, 천연벌꿀을 희석하여 제조한 mead와 벌꿀로 삼투압추출법에 의해 얻은 매실쥬스를 희석하여 제조한 매실 melomel의 발효 중 알코올함량, 환원당, 가용성고형분, pH 및 총산도의 변화를 조사하였다. 전반적으로 발효 속도는 mead보다 melomel이 훨씬 빨랐다. 환원당과 가용성 고형분(Brix)은 발효시작 후 16일까지 점차적으로 감소하였으며, 이 기간 동안에 알코올함량은 점차적으로 증가하였다. mead의 경우는 초기 5일까지는 환원 당량의 감소속도와 알코올 생성속도가 다소 지연되는 양상을 나타냈다. 발효 21일 후에는 mead의 알코올함량은 7.6%에 이르렀으며, 매실 melomel은 12.4%에 도달하였다. pH와 총산도는 발효 초기의 변화 외에는 전 발효기간 중 큰 변화를 보이지 않았다. 발효가 끝난 mead와 매실 melomel은 미세여과를 통하여 광투과도가 99.4%인 밝고 투명한 제품을 얻을 수 있었다. 결론적으로 벌꿀을 사용하여 삼투압법으로 추출한 과실을 사용하여 벌꿀발효주를 만드는 melomel의 제조법이 단순히 벌꿀만을 사용하는 mead의 제조법에 비해 장점을 갖음을 알 수 있었다.

• 한국응용곤충학회지
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• 제47권1호
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• pp.65-74
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• 2008

식물추출물(20과 35종)을 사용하여 미량국소처리방법과 분무방법으로 벼멸구 암컷성충에 대한 살충활성과 기피효과에 대해 실험을 수행하였다. 살충활성과 기피효과의 결과는 식물종과 그 부위에 따라 다양한 차이를 보였다. 인면과수, 구리광, 미국자리공의 줄기 추출물, 그리고 취춘과 석류나무의 잎+줄기 추출물이 벼멸구에 대하여 높은 살충활성을 보였다. 식물추출물들의 기피효과는 남학슬의 전부위 추출물, 캐슈나무의 열매추출물, 석류나무와 등나무의 잎+줄기 추출물이 높은 기피활성을 보였다. 이 실험에 사용한 식물추출물들에서 기피효과가 높은 식물추출물들의 살충활성이 불규칙적으로 나타나 기피효과와 살충률의 관계가 성립되지 않았다. 따라서 처리된 식물추출물의 벼멸구에 대한 살충활성과 기피 효과는 상관관계가 없음을 알 수 있다.

• 대한인간공학회지
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• 제33권5호
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• pp.313-321
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• 2014

Objective: The purpose of this study is to develop products that prevent muscular skeletal disease of farm workers, which would bring improvement for an efficient harvesting work. Background: A pretest for product development and a survey research was carried out to inspect the problems of current harvesting work procedure. The product was developed and assessed based on ideas to supplement and improve these weak points. Method: A total of twenty men were recruited to evaluate the effects of harvest baskets on the upper-limb muscle activity, working hours. For the usability evaluation, electromyogram and working hours of previous working method (disuse of harvest basket, one-hand carriage of the basket) and new working method with the usage of newly-developed harvest basket was examined. The whole anterior deltoid, biceps brachii and erector spinae on both sides, which make a total of six muscle parts, were used for this experiment. The results were analyzed using ANOVA with muscle activity (%MVC) of each three forms of work and required work time from SPSS 18.0. Results: According to the test result, all muscles did not demonstrate any statistically significant difference, with an exception of the backbone erector (right). The muscle activity of backbone erector (right) in the work method that uses the harvest basket developed in this study was detected to be approximately 23% less than that of the previous working method. Moreover, compared to the previous working method, the required work time decreased to a statistically significant degree. Conclusion: As such, the decrease in the amount of waist muscle usage at harvesting work would enable the prevention of muscular skeletal disease and stabilization of lumbar spine. Application: Which in turn would increase the effectiveness and reduce personnel expense (labor costs) while enhancing productivity with a decreased working hours.

• Preventive Nutrition and Food Science
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• 제19권3호
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• pp.178-186
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• 2014

Many recent studies have focused on maintaining a healthy life by preventing and/or postponing the aging process. Numerous studies have reported that continuous exposure to reactive oxygen species can stimulate skin aging and that excessive accumulation of fat can cause an impaired skin barrier and tissue structure alterations. Thus, the maintenance of antioxidant homeostasis and the suppression of adipose accumulation are important strategies for skin anti-aging. Here, we prepared three types of extracts [whole juice, acetone-perchloric acid (PCA), and ethanol] from 20 fruits and medicinal herbs native to the Gyeongnam area of Korea. The total phenolic content of each extract was analyzed, and we observed higher total phenolic contents in the medicinal herbs. Consistent with this, the results of the oxygen radical absorbance activity capacity assay indicated that the in vitro antioxidant activities of the medicinal herb extracts were stronger than those of the fruit extracts. The fruits and medicinal herbs had strong effects on cell-based systems, including $H_2O_2$-induced oxidative stress in human keratinocytes and 3T3-L1 lipid accumulation. Nishimura Wase persimmon, Taishu persimmon, wrinkled giant hyssop, sweet wormwood, Chinese cedar, red perilla, tan shen, hiyodori-jogo, and cramp bark may be natural anti-aging materials with effective antioxidant and anti-adipogenic activities. Taken together, our findings may provide scientific evidence supporting the development of functional foods and nutraceuticals from fruits and medicinal herbs.

• Asian Pacific Journal of Cancer Prevention
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• 제15권5호
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• pp.2159-2163
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• 2014

Background: Prostate cancer is the most frequently occurring cancer among males in economically developed countries. Among the several risk factors that have been suggested, only age, ethnicity, diabetes, and family history of prostate cancer are well-established and primary prevention of this disease is limited. Prior studies had shown that dietary intake could be modified to reduce cancer risk. We conducted a hospital-based, casecontrol study to examine the association between dietary patterns and prostate cancer risk in Iran. Materials and Methods: A total of fifty patients with prostate cancer and a hundred controls underwent face-to-face interviews. Factor analysis was used to determine the dietary patterns. Multivariate logistic regression was used to estimate odds ratios (ORs) and 95% confidence intervals (CIs). Results: We defined two major dietary patterns in this population: 'western diet'(high in sweets and desserts, organ meat, snacks, tea and coffee, French fries, salt, carbonated drinks, red or processed meat) and 'healthy diet' (high in legumes, fish, dairy products, fruits and fruit juice, vegetables, boiled potatoes, whole cereal and egg). Both Healthy and western pattern scores were divided into two categories (based on medians). Higher scores on Healthy pattern was marginally significantly related to decreased risk of prostate cancer (above median vs below median, OR =0.4, 95%CI=0.2-1.0). An increased risk of prostate cancer was observed with the higher scores on the Western pattern (above median vs below median, OR=4.0, 95%CI=1.5-11.0). Conclusions: The results of this study suggested that diet might be associated with prostate cancer among Iranian males.

• Asian-Australasian Journal of Animal Sciences
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• 제24권8호
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• pp.1086-1091
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• 2011

This experiment was designed to investigate the effect of lerak extract on the dynamic of rumen microbes in the in vitro fermentation of diet with different ratios of forage and concentrate. In vitro fermentation was conducted according to the method of Tilley and Terry (1963). The design of experiment was a factorial block design with 2 factors. The first factor was the ratio of forage and concentrate (90:10, 80:20, and 70:30 w/w) and the second factor was the level of lerak extract (0, 0.6, and 0.8 mg/ml). Total volatile fatty acid (VFA) concentration, proportional VFA and NH3 concentration were measured at 4 h incubation. Protozoal numbers in the buffered rumen fluid after 4 and 24 h of incubation were counted under a microscope. Bacterial DNAs of buffered rumen fluid were isolated from incubated samples after 24 h of incubation using a QiaAmp kit. Total bacteria, Fibrobacter succinogenes, Ruminococcus albus, and Prevotella ruminicola were quantified using real time polymerase chain reaction (PCR). Lerak extract markedly reduced protozoal numbers in buffered rumen fluid of all diets after 24 h of incubation. Total bacteria did not change with lerak extract addition. While no difference in F. succinogenes was found, there was a slight increase in R. albus number and a significant enhancement in P. ruminicola number by increasing the level of lerak extract in all diets. Propionate concentration significantly increased in the presence of lerak extract at level 0.8 mg/ml. It was concluded that the addition of lerak extract could modify rumen fermentation and had positive effects on rumen microbes.

• 한국식품과학회지
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• 제30권1호
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• pp.184-191
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• 1998

사과쥬스-우유 혼합시료와 포도쥬스-우유 혼합시료를 L. acidophilus (KCTC 2182)로 21시간 발효시키면서 휘발성 향기 성분의 변화를 관찰한 결과, 발효에 의해 생성된 diacetyl과 acetoin은 6시간 또는 12시간에 처음 탐지되기 시작하여 12시간에 가장 높은 수치를 보인 후, 그 후에는 감소하는 경향을 보였다. 시료중에 원래 존재하던 acetone과 butanol은 발효 과정에서 점차 감소하였다. 시료 중에 원래 존재하기도 하고, 발효에 의해 생성되기도 하는 ethanol의 함량은 사과쥬스-우유 혼합시료의 경우는 18시간에 가장 높았으며 그 후에는 다소 감소하였고, 포도쥬스-우유 혼합시료의 경우는 발효 전(全) 기간에 걸쳐서 높은 수치를 보였으나 18시간이 다른 시간보다 다소 높은 수치를 보였다. 사과쥬스에서는 ethanol이, 포도쥬스에서는 ethanol과 acetone의 경우 실험 결과에 영향을 미칠 정도의 높은 양이 검출되었다.

• 대한지역사회영양학회지
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• 제5권2호
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• pp.172-184
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• 2000

To establish a basic cohort which can survey the nutrient and food intake related to the health status of the middle and old-aged vertically, a longitudinal survey of 110 adults over forty years old was conducted three times in Chon-ju city over 5 years (1994-1999), and the influences of health status by changes in their nutrient and food intake were examined in this study. The results were as follows ; The number of subjects was 110(43 man, 67 women), 10.0% in their forties, 28.2% in their fifties, 45.4% in their sixties 6.4% over seventy, and their average age was 61.4. There were decrease of height about 1cm , increase of body fat % and few changes of BMI during the testing period. As the subjects were aging, the percentage of anemia increased, but averages of blood pressure and blood glucose(men : 91.8mg/㎗, women : 90.3mg/㎗) were constant. Total cholesterol increased from 196.7mg/㎗ to 212.6mg/㎗(P 0.05) over five years, and the numerical values for women were higher than that of men. In many cases, lack of nutrient intake was shown, as compared with the Recommended Dietary allowance(RDA) especially calcium and vitamin A(71.7%, 64.9% of RDA). Grains intake showed a tendency to decrease(P 0.01). On the contrary, fruit intake showed a tendency to increase(P 0.001). On whole meal, plant foods were 85.1% and animal foods were 14.9%. As dietary factors influencing health status were investigated, blood glucose was influenced by vitamin B$_2$, potatoes and triglyceride, DBP and SBP were affected by vitamin B$_1$, vitamin C, legumes, fishes, triglyceride and age. Total cholesterol was under the influence of triglyceride, milk, seeds and fat. BMI was influenced by iron, SBP, animal food, and age.