• Title/Summary/Keyword: Western Chemical Medicine

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An Outlook of the Oriental and Western Medical Diagnosis and Treatment on Large Bowel Cancer (대장암(大腸癌)의 동서의(東西醫) 결합(結合) 진치근황(診治近況))

  • Kim, Byeong-Ju;Moon, Goo
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.5 no.1
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    • pp.1-17
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    • 1999
  • Large bowel cancer shows the 4-5th frequency in cancers that occurs in Korea. The western medicine cures the Large bowel cancer by radiation, surgery and chemotherapy. While, Oriental medicine cures the Large bowel cancer by Herb-drugs, acupuncture, moxa and et al. With just one way of treating Large bowel cancer can't be effective remedy. Because each medicine has a strength and weakness, it is effective treatment when two medicine combines and supplement each other. We got the following result about a trend of oriental and western combination treatment for Large bowel cancer through studding records. 1. In Large bowel cancer, colon cancer is referred hematochezia(腸風下血), rectal cancer is refereed enterotoxin(腸毒), and anal cancer is accumulation of pathogens in yin(結陰). 2. The western medicine treats Large bowel cancer patient with surgery first. They need on assembly treatment such as chemical, radiation and immune treatment. In oriental medicine, they treats Large bowel cancer patients with differentiation of symptom and signs and treatment(辨證施治) for example, insufficiency of spleen and stomach(脾胃虛弱), collapse of the spleen-ql(脾氣下陷), stagnation of blood stasis and toxic agent(瘀毒內結), reinforcing both qi and blood(脾血下陷), stagnation of damp-phlegm(痰濕凝結) and cure for them by acupuncture and moxa too. 3. In combination with oriental and western medical treatment princple of Large bowel cancer by each stage is as follows. First stage is cured with radical surgery and herb-drugs without chemotherapy. The intermediate and terminal stage patients is used radiation before surgery, or after palliative surgery cour with chemotherapy, radiation and Herb-drugs. In terminal stage patients, unable for surgery, is used combination between chemotherapy, palliative radiation and Herb-drugs. 4. After radiation surgery, the terminal stage patients who have extensively lymph node metastasis or local contraindication is able to undergo combination of Herb-durgs and chemotherapy. 5. The cure-effect with oriental and western medicine combination treatment was better than that just with oriental or western medical treatment. 6. The merits of oriental and western medicine combination treatment lengthen one's life and diminish the bad effect of chemotherapy and complete radiation treatment, prevent from relapsing, maintain the balance in their environment of body and improve immunity.

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Knowledge-based Herbal Database for the Treatment of Atopic Dermatitis (아토피피부염 치료를 위한 지식기반의 생약 데이터베이스)

  • Shin, Jee-Young;Bae, Hyun-Su;Hong, Mu-Chang;Shin, Min-Kyu;Kim, Yang-Seok
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.24 no.6
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    • pp.1129-1133
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    • 2010
  • The treatment of Atopic dermatitis and its untapped herbal elements are recognized as possible solutions to incurable diseases stemming from overdosage of chemical drugs. Synthesizing clinical results from the Oriental medicine with scientific results from the field of Molecular biology is in the mainstream. The main goal of this research is, by objectifying the methodology of abstracting information into a compendium, to establish knowledge-based database on natural materials mingling every single related information from both Oriental and Western medicine. The constructed system, ATODERM, is the first database system about the medical herb for the treatment of Atopic Dermatitis which bearing the integrated information on Oriental medicine and Western medicine. The construction of this database renders new ways of treatment and prescriptions for researchers in the field of the Oriental medicine. Using the database that has been intensively accumulated, the possibility of creating the plausible cure for the disease can be anticipated.

The Introduction of Western Medicine and The Change of Body Conception (서양 의학의 수용과 신체관의 변화 - 최한기의 『신기천험(身機踐驗)』을 중심으로 -)

  • Kim, Moon-Yong
    • (The)Study of the Eastern Classic
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    • no.37
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    • pp.345-375
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    • 2009
  • In relation to body conception, the introduction of western medicine to Joseon Korea started off some points in disputes: the one was whether the western anatomy was positive or not, the other was whether the cognition was ruled by heart or brain. In the long run of these disputes, that who had clarified the change of body conception was Choi Han Kee. His new conception of body was characterized as follow: on the one hand, it emphasized the mechanical conception of body; on the other hand, it emphasized the cognitive ability of body. But that his conception of body had obscure points: that is, its mechanical conception was intervened by chi(神氣), and his doctrine of cognition searched for the origin of cognition in balance of chi of the body. He had set up this conception of body by the combination of western medicine and chi, but the combination did not seem to be perfect. This point had appeared again in his conception of physics that he thought the basis of medicine. He had pursed the combination of chemical element and chi, but it could not be accomplished successfully unless he had abandoned the organicist conception of chi. In conclusion, his new conception of body was not free from the suspicion of a incomplete tentative construction.

The study of Acontii Tuber in Bang-Yak-Hap-Pyun (부자(附子)를 포함(包含)하는 방약합편처방(方藥合編處方)에 대한 고찰(考察))

  • Song, In-sun;Oh, Min-seok;Song, Tae-won
    • Journal of Haehwa Medicine
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    • v.10 no.1
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    • pp.323-336
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    • 2001
  • Acontii Tuber is very toxious material, but In oriental medicine frequently used for emergency state like shock, coma, and severe pain and author study about Acontii Tuber in Bang-Yak-Hap-Pyun(方藥合編). Bang-Yak-Hap-Pyun(方藥合編) is widely used for clinical herbal prescpition book. Acontii Tuber has alkaloid. this chemical compound make toxious state like arrythmia, heart arrest, weakness, numbness, itching. And using this material must be careful. In Bang-Yak-Hap-Pyun(方藥合編) Acontii Tuber is used 1.2g ~ 12g. and it decrease pain, inflammation, increase activity of heart, and Acontii Tuber' commom use is severe pain disease. Raw Acontii Tuber(生附子) is rarely used, mostly roasted Acontii Tuber. In case of Acontii Tuber toxic state, in oriental medicine Gam-du-tang(甘豆湯) & Go-sam(苦蔘) is used, in western medicine atropine & lidocane is used.

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Adenoviral Vector Mediates High Expression Levels of Human Lactoferrin in the Milk of Rabbits

  • Han, Zeng-Sheng;Li, Qing-Wang;Zhang, Zhi-Ying;Yu, Yong-Sheng;Xiao, Bo;Wu, Shu-Yun;Jiang, Zhong-Liang;Zhao, Hong-Wei;Zhao, Rui;Li, Jian
    • Journal of Microbiology and Biotechnology
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    • v.18 no.1
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    • pp.153-159
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    • 2008
  • The limitations in current technology for generating transgenic animals, such as the time and the expense, hampered its extensive use in recombinant protein production for therapeutic purpose. In this report, we present a simple and less expensive alternative by directly infusing a recombinant adenovirus vector carrying human lactoferrin cDNA into rabbit mammary glands. The milk serum was collected from the infected mammary gland 48 h post-infection and subjected to a 10% SDS-PAGE and Western blotting. An 80-kDa protein was visualized after viral vector infection. With this method, we obtained a high level of expressed human lactoferrin of up to 2.3mg/ml in the milk. Taken together, the method is useful for the transient high-level expression recombinant proteins, and the approach established here is probably one of the most economical and efficient ways for large-scale production of recombinant proteins of biopharmaceutical interest.

A Personal Perspective and Our Role in Korean Oriental Medicine (한의학(韓醫學)의 전망(展望)과 우리의 역할(役割))

  • Kang Shun-Su
    • Herbal Formula Science
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    • v.10 no.2
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    • pp.1-4
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    • 2002
  • The development of Korean Oriental medicine is based upon the accumulation of experience and knowledge gathered over the centuries. The approaches taken are holistic and empirical. There is a need to understand their actions at molecular levels with more rational, objective and scientific studies. Today it appears that Chronic and age-associated diceases may be multifactorial and hence more complex. A different approach may be required. One claimed usage of Korean Oriental medicine is for the treatment and prevention of chronic and age-associated illnesses. Some of the botanical formulas used for this purpose were discovered thousands of years ago and continue to be used today. There are indications that these formulas may indeed be helpful in the treatment or prevention of chronic diseases. This multi-component medicine could not only be very useful meeting the unmet clinical needs but for defining a more synergistic therapy that supports and maintains the bodies natural curative abilities. The potential usefulness of Korean Oriental medicine embodies the belief of maintaining healthy homeostasis of the body through the proper balance of a mixture of chemical at different organs or tissues. This concept is different from western medicine and implies that multiple compounds may act on multiple mechanisms of action to maintain the balance of the complex web of biology. This is very important in view of sciences current direction to integrate fragmented information to develop future medicines. The western and eastern approaches to human health and disease are complementary to each other. The best approach in developing future medicines is to integrate both approaches.

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Antitumor and Apoptosis Induction Effects of Paeonol on Mice Bearing EMT6 Breast Carcinoma

  • Ou, Yetao;Li, Qingwang;Wang, Jianjie;Li, Kun;Zhou, Shaobo
    • Biomolecules & Therapeutics
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    • v.22 no.4
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    • pp.341-346
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    • 2014
  • Paeonol is a major phenolic micromolecular component of Moutan cortex Radicis, a traditional Chinese Medicine. It has shown antitumor effects in previous studies; however, the underlying mechanisms remain unknown. This study investigated the mechanism by giving treatments of placebo, cyclophosphamide, paeonol of 150 and 300 mg/kg to 4 groups of mice bearing EMT6 breast cancer. Apoptosis in tumor cells were confirmed by morphology analysis, including hematoxylin, eosin staining and TUNEL staining. The results showed that the weight of EMT6 breast tumor was significantly reduced in the groups treated with both 150 and 300 mg/kg of paeonol. Immunohistochemical and Western blot results showed that the expression of Bcl-2 was down-regulated while the expression of Bax, caspase 8 and caspase 3 was up-regulated respectively. These results suggest that paeonol exhibits antitumor effects and the mechanism of the inhibition is via induction of apoptosis, regulation of Bcl-2 and Bax expression, and activation of caspase 8 and caspase 3.

A Study Of Effects on Renal Function from Continuous Long-Term Herbal Medication (단일 한약 복합 처방의 장기간 연용 투여가 신기능에 미치는 영향에 대한 전향적 연구)

  • Yoon, Yeo-Kwang;Sun, Teh-Cheng;Song, Woo-Sup;Kwon, Su-Kyung;Jang, Hae-Jin
    • The Journal of Internal Korean Medicine
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    • v.25 no.4
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    • pp.300-305
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    • 2004
  • Background : Due to increased interest in herbal medicines is recent years, medical circles have made studies of toxicity and side effects of herbal medicines. Particularly the kidney is sensitive to toxicity. A few reports concerning the side effects and toxicity of herbal medicine have been presented recently. This has bought on some distrust in herbal medicines among patients and western doctors. Objectives : The purpose of this study is to determine what effects long-term prescription of one herbal medicine may have on renal function. Methods : Nineteen patients took herbal medicine for eight weeks. Tests of their Blood Urea Nitrogen(BUN), Creatinine of blood plasma, and urine (chemical and microscopic) were taken before taking medicine and at the 2nd, 4th, 8th weeks. Results : After taking a herbal medicine, BUN and Creatinine decreased significantly or remained the same in comparison with the prior interval. Chemical and microscopic examination of urine showed no changes. Conclusions : The results suggest that taking this herbal medicine for a long time does not induce nephrotixicity. Further study is needed for investigating safety and toxicity of herbal medicines.

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Study on the Shin-myung(神明) activity of Brain and Brain hormon effect (뇌(腦)의 신명기능(神明機能)과 뇌(腦)의 호르몬 작용(作用)에 대(對)한 문헌적(文獻的) 고찰(考察))

  • Kim, Jin Hyung;Kim, Yun-Sik;Seol, In-Chan
    • Journal of Haehwa Medicine
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    • v.11 no.1
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    • pp.73-83
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    • 2002
  • This thesis was written in order to help set groundwork of the mutuality between brain hormon and Shin-myung(神明) activity. 1. Shin-myung(神明) means all spritual functions, and Shin(神) represents thinking, myung(明) represents consciounsness. 2. As a origin of Shin-myung(神明) activity, in ancient times Heart(心) was regared as one, but since Chung-Dynasty(淸朝), Brain(腦) is regared as a main controller to manage Shin(神) in human body. 3. Shin-myung(神明) activity would should between Brain(腦) and Shin-Sin(心神) 4. Hormon is chemical substance to serve convey infomations and stimuiate them. In Present day Western medical science, make an attempt to understand Shin-myung(神明) activity of Brain(腦) as a activity of hormon doings. In conculusion, Shin-myung(神明) represent that Brain(腦) inculde Mind-Sprit(精神) activety, and it can be able by the function of brain hormon activety.

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The Comparative Study of Oriental Medicine in Korea, Japan and China (한국(韓國)과 일본(日本) 및 중국(中國)의 동양의학(東洋醫學)에 대한 비교연구(比較硏究))

  • Cho, Ki-Ho
    • The Journal of Korean Medicine
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    • v.19 no.1
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    • pp.271-298
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    • 1998
  • During these days of new understanding, western medicine has developed remarkably and a revaluation of traditional medicine has been achieved. This appears to have resulted from the sound criticisms of what western medicine has achieved up to now; excessive subdivisions of clinical medicine, severe toxicity of chemical drugs, lack of understanding about patients complaints which cannot be understood objectively, and etc. It is thought that the role of traditional medicine will be more important in the future than it is now. Someone said that the research methods of traditional medicine depends on the way of experimental science too much. That there was no consideration of a system for traditional medicine and the critic also went so far as to assert that in some cases the characteristics of eastern ideas is to permit irrationalism itself. In view of this thinking, the term traditional medicine seems to have been used somewhat too vaguely. However, traditional medicine is a medical treatment which has existed since before the appearance of modern medicine and it was formed from a traditional culture with a long history. One form of traditional medicine, oriental medicine based upon ancient Chinese medicine, was received in such countries as Korea, Japan, Thailand, Vietnam, Tibet, and Mongolia. Oriental medicine then developed in accordance with its own environment, race, national characteristics, and history. Although there are some simultaneous differences between them, three nations in Eastern Asia; Korea, Japan, and China, have especially similar features in their clinical prescriptions and medical literature. These three nations are trying to understand each others unique traditional medicines through numerous exchanges. Even though many differences in their ways of studying have developed over history exist, recent academic discussions have been made to explore new ways into oriental medicine. Therefore a comparative study of oriental medicine has gradually been thought to be more important. In Korea the formation of a new future-oriented paradigm for oriental medicine is being demanded. The purpose of the new paradigm is to create a new recognition of traditional culture which creates an understanding of oriental medicine to replace the diminished understanding of oriental medicine that was brought about by the self-denial of traditional culture in modem history and cultural collisions between oriental and occidental points of view. Therefore, to make a new paradigm for oriental medicine which is suitable for these days, and fortifies the merit of oriental medicine while compensating its defects, the author has compared the characteristics of oriental medicines in Korea, Japan, and China. The conclusions of this research are as follows: 1. The fundamental differences of the traditional medicines of these three nations are caused by the differences in the systems of Naekyung and Sanghannon. 2. The pattern-identification of illnesses is generally divided into two categories; the pattern identification of Zang-Fu and the pattern identification of prescription. 3. There are many differences in the definition of terms, such as Yin and Yang, Deficiency and Excess, and etc. 4. Chinese traditional medicine has some new concepts about pattern identification and epidemic febrile disease. 5. Japanese traditional medicine has some characteristics about pattern identification of the whole bodys condition and signs of abdominal palpation. 6. In terms of the effects of herbal drugs, Chinese traditional medicine attaches great importance to the experiential efficacy of the herb, and Japanese traditional medicine is taking a serious view of the effects of experimental medical actions.

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