• 제목/요약/키워드: Weight losses

검색결과 349건 처리시간 0.028초

택란 분획물이 당뇨유발 흰쥐에서의 혈당강하에 미치는 영향 (The antidiabetic properties of fractions of Lycopus lucidic Turcz in streptozotocin diabetic rats)

  • 김명화
    • 한국식품조리과학회지
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    • 제16권6호
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    • pp.644-651
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    • 2000
  • This study was carried out to evaluate the effects of fractions of methanol(MeOH) extracts of Lycopus lucidic Turcz on hyperglycemia and energy metabolites in streptozotocin(STZ) diabetic rats. Diabetes mellitus was induced in male Sprague-Dawley rats weighing 200-220 g by an injection of STZ dissolved in a citrate buffer into the tail vein at a dose of 45 mg/kg of body weight, and the rats were divided into 7 groups, that is, one normal group and 6 diabetic groups: STZ-control, hexane, chloroform(CHCl$\sub$3/). ethylacetate(EtOAc), butanol(BuOH) and H$\sub$2/O fraction-fed groups. All groups were fed an AIN-93 diet and the fractions of Lycopus lucidic Turcz were administered orally with 2 % Tween 80 for 14 days after the STZ injection. Body weight, diet intake and organ weights were monitored. The plasma levels of blood glucose, insulin and protein were determined. The plasma concentrations of cholesterol, HDL-cholesterol, triglycerides and free fatty acid were assayed. The plasma activities of aspartate aminotransferase (AST) and alanine aminotransferase(ALT) were also measured. Body weight losses were observed by feeding the fractions of Lycopus lucidic Turcz in STZ experimental groups, and the kidney weight was increased. The extent of blood glucose decrement was significantly greater in the hexane and BuOH fraction-fed groups than STZ-control group. The plasma protein level was significantly lower in the H$\sub$2/O fraction-fed group. The plasma cholesterol level was decreased in BuOH and H$\sub$2/O fraction-fed groups compared with the STZ-control group. The levels of free fatty acids in the CHC1$\sub$3/ and H$\sub$2/O fraction-fed groups were significantly decreased(p<0.05). ALT activitiy of BuOH fraction-fed group was lower than control but it was not significantly different. These results suggest that the fractions of Lycopus lucidic Turcz are capable of lowering blood glucose and fat metabolites concentrations when administered to STZ-treated rats, and AST/ALT activity and insulin levels show the possibility of therapeutic use to diabetes mellitus.

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당뇨 유발 흰쥐에서 삼채뿌리 첨가 식이가 혈당과 지질 수준에 미치는 영향 (Effect of Allium hookeri Root on Plasma Blood Glucose and Fat Profile Levels in Streptozotocin-Induced Diabetic Rats)

  • 김명화
    • 동아시아식생활학회지
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    • 제26권6호
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    • pp.481-490
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    • 2016
  • This study was designed to examine the effects of Allium hookeri (AH) on plasma blood glucose and fat profile levels in diabetic rats. Diabetes mellitus was induced in male Sprague-Dawley rats through injection of streptozotocin (STZ) dissolved in citrate buffer into tail veins at a dose of 45 mg/kg of body weight. Sprague-Dawley rats were then fed for 4weeks, with the experimental groups receiving a modified diet containing 5% or 10% powder derived from AH roots. The experimental groups were divided into four groups, consisting of a control group, STZ-control group, and diabetic fed with AH 5% & 10% treated groups. Rats' body weights, blood glucose, total cholesterol, HDL-cholesterol, triglyceride (TG), and free fatty acid (FFA) values in plasma were measured along with hematocrit (Hct) values and aminotransferase activities. Body weight losses were observed in the STZ-control group, whereas the STZ-AH group of diabetic rats gained weight. There was a significantly decrease in brain weight of the STZ-AH group but no significant differences in kidney and liver weights of the STZ-AH 5% & STZ-AH 10% groups compared to the STZ-control group. Blood glucose was significantly reduced in the STZ-AH 5% & STZ-AH 10% diabetic groups. There were no significant differences in total cholesterol and TG levels among the diabetic groups. HDL-cholesterol significantly increased while FFA significantly decreased in the STZ-AH 5% & STZ-AH 10% diabetic groups. The Hct level of the STZ-AH group was lower than that of the STZ-control group. Aspartate aminotransferase activity was significantly reduced in the STZ-AH 5% & STZ-AH 10% diabetic groups. These results indicate that supplementation with Allium hookeri root may have beneficial effects on diabetic complications as a potential therapeutic candidate.

Detent Force Reduction of a Tubular Linear Generator Using an Axial Stepped Permanent Magnet Structure

  • Eid Ahmad M.;Lee Hyun-Woo;Nakaoka Mutsuo
    • Journal of Power Electronics
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    • 제6권4호
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    • pp.290-297
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    • 2006
  • Various methods have been discussed to reduce detent force in a tubular permanent magnet type linear single phase AC generator. In particular, the proposed methods depend on variations of the permanent magnet construction. These methods include two approaches in the form of sloped magnets, and conical magnets in addition to the conventional method of optimizing the magnet length. The undesired detent force ripples were calculated by a two dimensional Finite Element Method (FEM). Moreover, the generated electromotive force in the stator coils was calculated for each configuration of the permanent magnet. The experimental results agreed well with those obtained from the FEM-based simulations. Sufficient reduction in the detent force was achieved over the range of 40% while the root mean square of the output voltage was maintained. It was found that sloping the permanent magnet decreased the detent force and at the same time increased the generated rms voltage of the AC generator. The performance of the designed linear AC generator was evaluated in terms of its efficiency, total weight, losses, and power to weight ratio.

Effect of Parasitoids' Exit and Predators' Ingress Holes on Silk Yield of the African Wild Silkmoth, Gonometa Postica Walker (Lepidoptera: Lasiocampidae)

  • Fening, Ken Okwae;Kioko, Esther Ndaisi;Raina, Suresh Kumar
    • International Journal of Industrial Entomology and Biomaterials
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    • 제19권2호
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    • pp.265-268
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    • 2009
  • Wild silkmoths can be utilised sustainably in the production of silk as an income for resource-poor rural communities. However, attack by parasitoids and predators affect the quality of cocoons and quantity of raw silk produced. A laboratory experiment was undertaken to quantify the effect of parasitoids' (dipteran and hymenopteran) and predators' (ants) exit and ingress holes, respectively, on silk production. The mean number of shells required to produce fifty grams of raw silk was highest with cocoons parasitised by a dipteran and lowest with unattacked cocoons (but with moths already emerged). Degumming loss was highest in parasitised and lowest in unttacked cocoons, but both were not different from cocoons predated by ants. Shell weight was highest in unattacked cocoons, followed by hymenopteran-parasitised and predated cocoons, with the dipteran parasitized ones being the least. Single cocoon weight was greater in hymenopteran-parasitised and predated cocoons than the dipteran-parasitised and unattacked cocoons. Shell ratio or raw silk, floss and yarn weights were higher in unattacked than parasitised and predated cocoons. The total loss in raw silk attributable to attack by parasitoids and predators ranged between 17.4~31.2%. The results offer baseline information for assessment of economic losses in wild silk farming due to parasitoids and predators in the field.

Therapeutic potential of traditionally used medicinal plant Andrographis paniculata (Burm. F.) against diabesity: An experimental study in rats

  • Thakur, Ajit Kumar;Chatterjee, Shyam Sunder;Kumar, Vikas
    • 셀메드
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    • 제4권1호
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    • pp.7.1-7.8
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    • 2014
  • Metabolic effects of ten daily doses of standardized extract of Andrographis paniculata leaves (AP) rich in andrographolide were evaluated in a rat model of type-2 diabetes and in diet induced obese rats. AP was administered per-orally as suspension in 0.3% carboxymethylcellulose at doses of 50, 100 and 200 mg/kg/day for 10 consecutive days. Blood glucose, insulin and lipid profile of rats were measured by using enzyme kits. In addition, effects of such treatments on anti-oxidant enzymes activity and histopathological changes in various organs of diabetic rats were assessed. AP treatments reversed body weight losses and increased plasma insulin level in diabetic rats. The anti-oxidant enzymes activity became normal and histopathological changes observed in pancreas, liver, kidney and spleen of diabetic animals were less severe in extract treated groups. On the other hand, hyperinsulinemia and increased body weight gains observed in high fat or fructose fed rats were less severe in the extract treated groups. These observations revealed therapeutic potentials of the extract for treatments of diabesity associated metabolic disorders, and suggest that the effects of the extract on insulin homeostasis depend on the metabolic status of animals. Activation of cytoprotective mechanisms could be involved in its mode of action.

Rheology of Slurries and Effects of Polymer Volume Ratio in Aqueous PZT Tape Casting

  • Yoon, Seok-Jin;Shin, Hyo-Soon;Lee, Dong-Kyun;Kang, Chong-Yun;Park, Ji-Won;Kim, Hyun-Jai
    • The Korean Journal of Ceramics
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    • 제7권1호
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    • pp.16-19
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    • 2001
  • For the fast dry of the aqueous tape, the process which water was reaplaced by organic solvent was proposed. Socalled, it was the solvent washing dry. Three organic solvents (methanol, ethanol and acetone) were selected for the washing solvent. The weight loss of the washed tapes was measured to evaluate the dry rate of the tapes and dried tapes were examined the generation of the cracks with the variations of the organic solvent and the washing time. Methanol, ethanol and acetone were available organic solvents for this method. The tapes washed in methanol, ethanol and acetone were dried rapidly for twenty minutes. After thirty minutes, the weight losses were not found any more, The solvent of the lower surface tension can decreases the crack of dried tape. If solvent substitutes water completely, though it was fast dried, crack can be eliminated.

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Solvent Washing Dry Method for Aqueous Tape Casting

  • Yoon, Seok-Jin;Shin, Hyo-Soon;Park, Ji-Won;Kang, Chong-Yun;Kim, Tae-Song;Kim, Hyun-Jai
    • The Korean Journal of Ceramics
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    • 제7권2호
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    • pp.55-57
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    • 2001
  • For the fast dry of the aqueous tape, the process which water was replaced by organic solvent was proposed. Socalled, it was the solvent washing dry. Three organic solvents (methanol, ethanol and acetone) were selected for the washing solvent. The weight loss of the washed tapes was measured to evaluate the dry rate of the tapes and dried tapes were examined the generation of the cracks with the variations of the organic solvent and the washing time. Methanol, ethanol and acetone were available organic solvents for this method. The tapes washed in methanol, ethanol and acetone were dried rapidly for twenty minutes. After thirty minutes, the weight losses were not found any more. The solvent of the lower surface tension can decreases the crack of dried tape. If solvent substitutes water completely, though it was fast dried, crack can be eliminated.

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High-Power-Density Power Conversion Systems for HVDC-Connected Offshore Wind Farms

  • Parastar, Amir;Seok, Jul-Ki
    • Journal of Power Electronics
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    • 제13권5호
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    • pp.737-745
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    • 2013
  • Offshore wind farms are rapidly growing owing to their comparatively more stable wind conditions than onshore and land-based wind farms. The power capacity of offshore wind turbines has been increased to 5MW in order to capture a larger amount of wind energy, which results in an increase of each component's size. Furthermore, the weight of the marine turbine components installed in the nacelle directly influences the total mechanical design, as well as the operation and maintenance (O&M) costs. A reduction in the weight of the nacelle allows for cost-effective tower and foundation structures. On the other hand, longer transmission distances from an offshore wind turbine to the load leads to higher energy losses. In this regard, DC transmission is more useful than AC transmission in terms of efficiency because no reactive power is generated/consumed by DC transmission cables. This paper describes some of the challenges and difficulties faced in designing high-power-density power conversion systems (HPDPCSs) for offshore wind turbines. A new approach for high gain/high voltage systems is introduced using transformerless power conversion technologies. Finally, the proposed converter is evaluated in terms of step-up conversion ratio, device number, modulation, and costs.

황산구리와 탄산나트륨 처리 목재 내의 물불용성 구리화합물의 생성과 방부효력 (Formation and Preservative Effectiveness of Water-Insoluble Copper Compound in Wood Treated with Copper Sulfate and Sodium Carbonate)

  • 김진경;이종신
    • 한국가구학회지
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    • 제19권5호
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    • pp.358-364
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    • 2008
  • Wood-inorganic material composite (WIC) was prepared by impregnating wood with copper sulfate ($CuSO_4\;5H_2O$) solution and by immersed wood in sodium carbonate($Na_2CO_3$) solution in order to introduce insoluble copper compounds {copper carbonate hydroxide, $CuCO_3\;Cu(OH)_2$} into the wood to give fungicidal effects in treated-wood. The weight percent gains (WPGs) of treated wood reached maximum value by impregnation of 20% copper sulfate solution and immersion in about 15% sodium carbonate solution for 24 hrs. Inorganic substances were present mainly in the lumina and cross-field pitting of tracheides. These substances were proved to be the insoluble copper carbonate hydroxide against water by the energy dispersive X-ray analyzer in conjunction with a scanning electron microscope (SEM-EDXA). The treated specimens showed high preservative effectiveness because the weight losses were hardly occurred by the fungi degradation test.

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Effect of Fat Level and the Ripening Time on Quality Traits of Fermented Sausages

  • Yim, Dong-Gyun;Jang, Kyoung-Hwan;Chung, Ku-Young
    • Asian-Australasian Journal of Animal Sciences
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    • 제29권1호
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    • pp.119-125
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    • 2016
  • The objective of this study was to investigate the effect of the fat reduction on the physicochemical and microbiological characteristics of fermented sausages during ripening and drying. Low fat fermented sausages were produced with different fat levels (30%, 20%, 10%, and 5%) under ripening conditions and fermented process. Samples from each treatment were taken for physicochemical and microbiological analyses on the 0, 1, 2, 3, 4, 5, 7, 10, 14, and 21st day of ripening. In proximate analysis, the fat reduction in sausages produced an increase in moisture, protein and ash contents during ripening and drying (p<0.05). The weight losses were significantly higher in high fat formulations during the first 4 days, whereas those were higher in low fat ones after 10 days of storage (p<0.05). Fat reduction was responsible for an increase in shear force values after 3 days of storage. The volatile basic nitrogen (VBN) value of the low fat samples was significantly higher (p<0.05). Low fat sausages reduced the extent of lipid oxidation. The lower fat level produced redder sausages. Total plate bacteria and Pseudomonas counts of sausages showed no significant differences. Production of low fat sausages resulted in the physicochemical and microbiological attributes equal to or better than the high fat sausages without negative effects, except only a higher VBN and weight loss.