• International Journal of Industrial Entomology and Biomaterials
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• v.27 no.2
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• pp.312-316
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• 2013

Caffeine is a thermogenic agent that can be used in weight loss products. In order to achieve a sustained release of caffeine, silk fibroin (SF) film was uses as carrier. It has been shown that the loading method of caffeine into SF film affected the uniform distribution of caffeine in the SF film. When caffeine was added directly into SF solution, gelation has been occurred immediately and prevented the uniform distribution of caffeine. On the other hand, caffeine was dissolved in methanol in order to load the caffeine in SF film and crystallize the SF film at the same time. However, due to the fast evaporation of methanol, caffeine was recrystallized on the surface of SF film rather than penetrating into the film. Finally, caffeine was loaded into pre-crystallized SF film and uniform distribution of caffeine could be achieved. There was an initial burst of caffeine during the first 15 min, but after that a sustained release was achieved.

• Biomolecules & Therapeutics
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• v.4 no.2
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• pp.202-204
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• 1996

Clonidine, an antihypertensive drug, stimulates postsynaptic $\alpha_2$adrenergic receptors in the CNS and lowers arterial pressure by erects on both cardiac output and peripheral resistance. However, many patients experience that sedation and xerostomia occured upon oral administration of clonidine. These side effects are due to high plasma peak concentration and can be avoided when clonidine is given transdermally. In this study, we performed the skin irritation test for transdermal administration of clonidine patch on New Zealand white rabbits. Twelve New Zealand white rabbits were divided into two groups according to the dose levels, respectively. After transdermal administration of clonidine patch with two doses, clinical manifestations, body weight loss and postmortem findings were observed. We could not find any significant evidence of skin irritation by transdermal administration of clonidine patch.

• Journal of Digital Convergence
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• v.19 no.3
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• pp.371-378
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• 2021

The purpose of study was to evaluate the usefulness a skin patch containing chlorogenic acid to the skin to identify changes in body fat and weight. 16 volunteers, consisting of 8 experimental groups and 8 control groups, participated in the study, and the study period was conducted for 4 weeks from Aug 03, 2020 to Aug 31, 2020. As a result of the inter-group effect test, there was no significant difference in body fat (F=4.38, p<.055), but it can be said that the experimental group had a positive effect because the difference in posterior score was larger than that of the control group. In the change of body weight, it was found that there was a significant difference in weight loss in the experimental group (F=9.43, p<.008). It will be meaningful as a preliminary study applying patches to studies related to obesity, and we hope that the results of the study will be used as basic data for research on patch materials in the future.

• Proceedings of the Korean Society For Composite Materials Conference
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• 2005.11a
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• pp.35-38
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• 2005

The Objective of this work was to design Composite Antenna Structures (CAS) and investigate impact behavior of CAS which was various curvature. This term, CAS, indicates that structural surface becomes antenna. Constituent materials were selected considering electrical properties, dielectric constants and tangent loss as well as mechanical properties. For the antenna performance, microstrip antenna layers inserted into structural layers were designed for satellite communication at the resonant frequency of 12.5 GHz and final demonstration article was. After making five kinds of curved CAS, which radii of curvature are flat, 200, 150, 100, 50 mm. The antenna performance changed in accordance with variation of curvature. The Reflection coefficient was independent of curvature but the gain decreased with the radius of curvature. The impact test equipment was Dyna-8250 drop weight tester. The impact characteristic in accordance with curvature is maximum absorb energy is same each other. The impact energy was 8.5 J. For various Impact energy test, five energy levels 3 J, 5 J, 7 J, 10 J, 20 J were used. The performance of impact damaged antenna was estimated by measuring the return loss and the radiation pattern. It was revealed that the performance of antenna was not related to the impact damage. Because the impactor did not damage the patch directly. CAS have good impact stability for the antenna performance.

• Journal of Space Technology and Applications
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• v.1 no.1
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• pp.33-40
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• 2021

Based on the requirements of a total weight of 42 kg or less, the NEXTSat-2 SAR (synthetic aperture radar) system was developed. As the NEXTSat-2 is a small-sized satellite, the SAR system was designed to account for about 40% of the dry mass of the payload relative to the total mass. Among the major components of the SAR system - which are an antenna, an RF transceiver, a baseband signal processor, and a power unit - a part with a particularly large dry mass is the antenna, the core of the SAR system. Whereas various selections are possible in consideration of gain and efficiency when designing the antenna, the micro-strip patch array antenna was adopted by reflecting the dry mass, power, and resolution required by the NEXTSat-2 project. In order to meet the mission requirement of the NEXTSat-2, the antenna was developed with a frequency of 9.65 GHz, a gain of 42.7 dBi, and a return loss of -15 dB. The performance of the antenna was verified by conducting a field test onboard the vehicle.