• Herbal Formula Science
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• v.16 no.2
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• pp.183-191
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• 2008

Acetaminophen (N-acety1-p-aminophenol, paracetamol) is widely used as an over-the-counter analgesic and antipyretic drug. Intake of a over dose of acetaminophen may result in severe hepatic necrosis. In this study, we investigated the liver damage in mice using single dose (300 mg/kg) of acetaminophen and the possible protective effects of administration (50-200 mg/kg body weight) of SB-Ex on acetaminophen-induced liver damage in mice. The alanine aminotransferase (ALT), and aspartate aminotransferase (AST) activities were determined in the plasma of mice. The effect of SB-Ex on lipid peroxidation product thiobarbituric reacting substances (TBARS) and some antioxidant enzymes superoxide dismutase (SOD), catalase, d-aminolevulinate dehydratase (${\sigma}$-ALA-D) activities, and gluthathione peroxidase (GPx), were also evaluated in the mouse liver homogenate. Acetaminophen caused liver damage as evident by statistically significant increased in plasma activities of AST and ALT. There were general statistically significant losses in the activities of SOD, catalase, ${\sigma}$-ALA-D, and GPx and an increase in TBARS in the liver of acetaminophen-treated group compared with the control group. However, SB-Ex was able to counteract these effects. These results suggest that SB-Ex can act as hepatoprotectives against acetaminophen toxicity and is a good candidate for further evaluation as an effective chemotherapeutic agent.

• Journal of Korean Society of Forest Science
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• v.80 no.3
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• pp.303-310
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• 1991

Seasonal patterns of decomposition and nutrient release from the needle litter were examined using litter-bags in coastal Pinus thunbergii forests in nothern Kyushu, Japan. Dry matter losses from decomposing needle litter were smillar in all standsover a experimental period. Mass loss in dry weight is lost rapidly during the first year, and thereafter the rate of loss slows. Litter lost approximately 40% of initial mass in 1 yr. The predicted decay constant, k values ranged from 0.5 to 0.6 Decomposition half-times($t_{0.50}$) ranged from 1.1 to 1.4 year. In the decomposing needle litter, the concentrations of N and P generally increased with time while the concentration of K decreased. A decrease in absolute amount was noted for K during decomposition while in an increase was found for N. The order of mobility of elements was K>P>N. Mineralization phase of N had not appeared during the experiment.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.26 no.1
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• pp.45-50
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• 1990

The basic investigation of the sea eel pots fisheries by questionnarie observation and dimension of the pots by fishing operation were carried out in order to develop for mechanical hauling system with 20~50 gross tonnage fishing boats from June to December, 1988. Number and weight of fish per pot between smaller diameter 11cm and larger 13cm of the pot have no significance so that the drag of the smaller pots can be decreased about 20% than the larger pots. The operating time by two men from opening to closing with screwing lock entrance was slightly faster than that by three men with knotting entrance even though the losses with two kinds of entrances while fishing operation were about the same. It was very reasonable that stone and lead sinker on the main line were substitute for two or three lead core P.P rope to make it smooth surface of the main line for mechanization of the continuous fishing operation.

• Korean Journal of Veterinary Research
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• v.35 no.1
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• pp.137-142
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• 1995

Anaplasmosis is a tick-borne disease of large and small ruminants, causing losses through mortality, abortion, weight loss and reduced milk production. In one dairy farm, for example, 250 of a total of 800 imported goats were diagnosed with a mysterious type of anemia during the summer and autumn of 1992. The etiologic agent was identified as Anaplasma spp by acridine orange and ultrastructure by electron microscopy. In order to monitor variations in blood biochemical and hematological parameters associated with the disease, blood samples were collected by jugular venipuncture from 50 goats at 3 month intervals between the period of February and October, 1993. The levels of RBCs, HB and HCT decreased from $18.48{\pm}1.96$ to $13.47{\pm}2.48X10^6/mm^3$, $12.25{\pm}1.41$ to $9.54{\pm}1.77g/dl$, and $43.09{\pm}4.75$ to $30.93{\pm}5.78%$, respectively. The values of MCH(Mean corpuscular hemoglobin), MCHC(Mean corpuscular hemoglobin concentration) and PLT(Platelet) were elevated from $6.58{\pm}0.30$ to $7.05{\pm}0.47pg$, $28.40{\pm}1.20$ to $30.82{\pm}1.85g/dl$ and $1688.34{\pm}750$ to $2046.82{\pm}783X10^3/mm^3$, respectively. Percent parasitized erythrocytes(PPE) increased from $0.61{\pm}0.5$ to $2.22{\pm}1.9%$, clinical biochemical parameters aspartate aminotransferase and alanine aminotransferase were $66.64{\pm}23.1K.U$ and $14.90{\pm}6.59K.U$, respectively and persisted at high levels throughout the observation period. The level of albumin(2.46)0.52 g/dl) was decreased corresponding to an elevated globulin and a reduced albumin/globulin ratio in October as compared with the values in February. It is concluded that caprine anaplasmosis may be an important cause of anemia and hepatic malfunction in goats.

• Economic and Environmental Geology
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• v.29 no.3
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• pp.269-279
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• 1996

Dehydroxylation and mullitization of primary and secondary kaolins were investigated in order to compare and understand the differences in thermal behaviours by DTA and TG up to $1,100^{\circ}C$. Chemical analyses and EPMA of the samples revealed nearly ideal unit-cell formulae of kaolins. The weight losses of dickite and halloysite are 14% and 12.5% on the average, respectively. The activation energies of dehydroxylation of kaolin minerals were calculated according to Kissinger's approach which uses various heating rates in DTA to estimate the activation energy of thermal reactions. The activation energies of dehydroxylation of halloysites from Daemoung and Buksam mines are about $163kJmor^{-1}$ (white), $168kJmor^{-1}$ (pink), and $176kJmor^{-1}$ respectively. The activation energies of dickites collected from Sungsan and Ogmae mines are about $166kJmor^{-1}$ and $387kJmor^{-1}$. The asymmetric shape of endothermic peak in DTA, the relative intensities of OH-stretching bands in FTIR spectroscopy and the existence of residual XRD peaks of the samples which were heated at $550^{\circ}C$ for 2 hours indicate that Sungsan dickite may be more disordered than Ogmae dickite. The new phase formed in thermally treated samples in the range of $900^{\circ}C$ to $1,100^{\circ}C$ was identified as mullite by XRD on the basis of disappearing of the characteristic peaks of kaolins and increasing of amorphous background upon heat treatment. On further heating, loss of more water from dehydroxylate resulted in the formation of mullite and the characteristic X-ray diffraction patterns of mullite began to appear at about $900{\sim}1,000^{\circ}C$ in kaolins.

• Journal of Korean Medicine Rehabilitation
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• v.23 no.2
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• pp.49-61
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• 2013

Objectives : This study was conducted to determine whether or not Kangwhaldoche-tang(Qianghuodaozhi-tang) (KDT) aqueous extracts can protect articular cartilage losses on the Freund's complete adjuvant(FCA)-induced rat rheumatoid arthritis. Methods : 520, 260 or 130 mg/kg of KDT were orally administered once a day for 14 days from 14 days after FCA treatments, and 15 mg/kg of dexamethasone was intraperitoneally administered as reference drug in this experiment. Changes on the body weight, knee circumferences, gross arthritis score, inflammatory tissue prostaglandin(PG) $E_2$ levels were monitored with cartilage collagen components and glucosaminoglycans(GAGs) compositions - chondroitin sulphate, heparin sulphate and hyaluronic acid in the present study. Results : As results of FCA treatment, classic rheumatoid arthritis featuring dramatic decreases of the body weights, cartilage collagen and GAGs contents with increases of the knee circumferences, gross arthritis scores and inflammatory tissue $PGE_2$ levels, were demonstrated in the present study. However, these changes from FCA - induced rheumatoid arthritis were clearly inhibited by treatment of dexamethasone and all three different dosages of KDT. Although overall anti-inflammatory effects of KDT 520 mg/kg were lowered than those of dexamethasone 15 mg/kg treated rats, KDT 520 mg/kg showed more favorable preserve effects on the cartilage GAGs and KDT 260 mg/kg treated rats showed similar preserve effects as compared with dexamethasone 15 mg/kg in this experiment. Conclusions : The present results supported that over 75 mg/kg of KDT showed favorable anti-arthritic effects on the FCA-induced arthritis mediated by suppression of $PGE_2$, representative inflammatory mediator, and may help improve rheumatoid arthritis.

• Magazine of the Korean Society of Agricultural Engineers
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• v.29 no.4
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• pp.132-141
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• 1987

The objective of the study was to obtain the compressive the tensile and the fleniril strengthes, thermal resistance, chemical resistance and fire resistance of the reclaimed plastic corcrete in order to investigate the feasibility as a new construction material This reclaimed plastic concrete is a compositive material which is composed of sand and blend of 50% of LDPE(Low density polyethylene) and 50% of HDPE (High density polyethylene) which are inexpensive and easy to reclaim. The results obtained in the study are summarized as follows: 1. As the binder content ranging from 20 to 40 % increase, the compresie, the splitting tensile and the flexural strengthes were increased. The compressive strenzth of the specimen tested was the highest and flexural strength the next and tensile strength the lowest 2. The compressive, the tensile and flexural strengthes of specimens made of fine sand were higher than those of coarse sand. The compressive, the tensile and the flexural strengthes of specimens made of high pressure molding were higher than those of low pressure molding. 3.In comparison with different additives, the specimens with carbon black was excellent and B. H. T. good and ferric oxide poor for thermal resistance. 4. In relationship between the flexural strength with varying temperature from -23$^{\circ}C$ to 80$^{\circ}C$. The flexural strengthes were decreared as temperature increased at 25 %, 30 % and 35 % of binder contents, respectively. Especially at 60$^{\circ}C$, the flexural strength was significantly decreased. 5. The decrement of flexural strengthes and the weight losses after 7 days immersion in acid or alkali solutions were not significant. 6. Fire resistance of the reclaimed plastic concrete was not significantly influenced by the contents of sand. However, the fire resistance of the reclaimed plastic concrete was depend upon melting and ignition properties of the binder itself. Therefore. a proper selection of the binder and the fire retardant are recommended in arder to improve fire resistance of the reclaimed plastic concrete.

• Restorative Dentistry and Endodontics
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• v.41 no.4
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• pp.255-261
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• 2016

Objectives: This study aimed to analyze the mineral composition of naturally- and artificially-produced caries-affected root dentin and to determine the elemental incorporation of resin-modified glass ionomer (RMGI) into the demineralized dentin. Materials and Methods: Box-formed cavities were prepared on buccal and lingual root surfaces of sound human premolars (n = 15). One cavity was exposed to a microbial caries model using a strain of Streptococcus mutans. The other cavity was subjected to a chemical model under pH cycling. Premolars and molars with root surface caries were used as a natural caries model (n = 15). Outer caries lesion was removed using a carbide bur and a hand excavator under a dyeing technique and restored with RMGI (FujiII LC, GC Corp.). The weight percentages of calcium (Ca), phosphate (P), and strontium (Sr) and the widths of demineralized dentin were determined by electron probe microanalysis and compared among the groups using ANOVA and Tukey test (p < 0.05). Results: There was a pattern of demineralization in all models, as visualized with scanning electron microscopy. Artificial models induced greater losses of Ca and P and larger widths of demineralized dentin than did a natural caries model (p < 0.05). Sr was diffused into the demineralized dentin layer from RMGI. Conclusions: Both microbial and chemical caries models produced similar patterns of mineral composition on the caries-affected dentin. However, the artificial lesions had a relatively larger extent of demineralization than did the natural lesions. RMGI was incorporated into the superficial layer of the caries-affected dentin.

• Proceedings of the Korea Concrete Institute Conference
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• 2008.04a
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• pp.529-532
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• 2008

Domestic area of most be happened chloride deicer damage. Because daily mean temperature is below 0$^{\circ}C$ from the area of domestic most. Use of deicing chemicals has been and will continue to be a major part of highway snow and ice control methods. Chloride-containing chemicals such as calcium chloride or rock salt are main deicers for the road. Extensive use of chloride deicers is, however, not only the source of substantial cost penalties due to their corrosive action and ability to deterioration roadway surface materials but also the source of environmental damages. Particularly, it has been recognized that chlorides present in deicing agents can significantly increase concrete surface scaling. In severe cases, scaling can result in dislodgement of coarse aggregate. This research estimates that pH and test of specific pollutants, dynamic modulus of elasticity for freeze-thaw test of concrete were higher than those NaCl, $CaCl_2$, and NaCl+$CaCl_2$(7:3, w/w), also weight losses for scaling test of concrete were much lower than those of NaCl, $CaCl_2$, and NaCl+$CaCl_2$(7:3, w/w).

• Korean journal of applied entomology
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• v.23 no.3 s.60
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• pp.153-157
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• 1984

The present work was designed to study the yield loss on rice at different appearance days of hopperburn caused by the brown planthopper(BPH), Nilaparvata lugens Stal, when rice plants were infested with BPH on booting and heading stages. Dead plants were colleted from 23 days after heading stage with intervals of 5 days. Yield losses by the initation of BPH infestation was greater at tooting than at heading stage. Compared to the uninfested plot, there was a reduction in 1,000 grain weight and filled grain percentage at both stages. Positive relationship was observed between rice yield(Y) and the number of days from heading to the appearance of the hopper-burn. Regression equations calculated were; for BPH feeding from booting $\hat{Y}(g)=10.145X-16.374(r=0.9726^{**})$, and for BPH feeding from heading $\hat{Y}(g)=9.792X+26.936(r=0.8850^{**})$.