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Effect of Acupuncture on Sciatica in Rat Models: Systematic Review and Meta-analysis (좌골신경통 백서모델에서 침치료의 효과: 체계적 문헌고찰 및 메타분석)

  • Yoon, Ye-Ji;Kim, Soojeon;Cho, Jae-Heung;Kim, Koh-Woon;Song, Mi-Yeon
    • Journal of Korean Medicine Rehabilitation
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    • v.30 no.1
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    • pp.79-93
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    • 2020
  • Objectives While sciatic neuropathy is one of the common symptoms which have the lifetime incidence of 13~40%, still there is no consensus about the standardized and the most effective conservative treatment. In addition, the importance of systematic review and meta-analysis of preclinical are growing as they could suggest possible effective treatment strategy for future studies. Therefore, we conducted systematic review and meta-analysis to estimate analgesic effect of acupuncture on sciatica in rat models. Methods Systematic search was conducted for all controlled comparative preclinical trials which assessed analgesic effect of acupuncture in sciatica rat models. Database of PubMed, EMBASE, Web of Science, CNKI and 6 Korean databases were used. The primary outcome was pain, which is evaluated by stimulus behavior tests in rat models. We assessed the methodological quality with Systematic Review Centre for Laboratory Animal Experimentation's risk of bias tool. RevMan 5.3 was used for meta-analysis and subgroup analysis was conducted according to treatment site, acupuncture point, treatment period and frequency used in electroacupuncture. Results 14 studies were finally included following our inclusion criteria. The data from meta-analysis indicated that the acupuncture significantly improved the result values of behavior tests for pain evaluation, compared to no-treatment control group in animal models (standardized mean difference=4.43, 95% confidence interval 3.16 to 5.69, Z=6.84, p<0.00001; χ2=68.02, p<0.00001; I2=82%). The results of subgroup analysis indicate that acupuncture treatment of unilateral site, distal acupoints, longer treatment period and applying 2/100 Hz frequency in electroacupuncture could be more effective. Conclusions Systematic review and meta-analysis of animal studies are getting important for the future clinical studies and the improvement of heatlh care. Therefore the results of the study would provide evidence and better design for the forthcoming studies.

Korea Barcode of Life Database System (KBOL)

  • Kim, Sung-Min;Kim, Chang-Bae;Min, Gi-Sik;Suh, Young-Bae;Bhak, Jong;Woo, Tae-Ha;Koo, Hye-Young;Choi, Jun-Kil;Shin, Mann-Kyoon;Jung, Jong-Woo;Song, Kyo-Hong;Ree, Han-Il;Hwang, Ui-Wook;Park, Yung-Chul;Eo, Hae-Seok;Kim, Joo-Pil;Yoon, Seong-Myeong;Rho, Hyun-Soo;Kim, Sa-Heung;Lee, Hang;Min, Mi-Sook
    • Animal cells and systems
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    • v.16 no.1
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    • pp.11-19
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    • 2012
  • A major concern regarding the collection and storage of biodiversity information is the inefficiency of conventional taxonomic approaches in dealing with a large number of species. This inefficiency has increased the demand for automated, rapid, and reliable molecular identification systems and large-scale biological databases. DNA-based taxonomic approaches are now arguably a necessity in biodiversity studies. In particular, DNA barcoding using short DNA sequences provides an effective molecular tool for species identification. We constructed a large-scale database system that holds a collection of 5531 barcode sequences from 2429 Korean species. The Korea Barcode of Life database (KBOL, http://koreabarcode.org) is a web-based database system that is used for compiling a high volume of DNA barcode data and identifying unknown biological specimens. With the KBOL system, users can not only link DNA barcodes and biological information but can also undertake conservation activities, including environmental management, monitoring, and detecting significant organisms.

The Moderating Role of Site Usage Experience in Internet Users' Decision on Personal Information Disclosure (개인정보제공 의사결정에 있어서 사이트 이용경험의 조절효과에 대한 연구)

  • Lee, Dong-Joo
    • Informatization Policy
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    • v.19 no.2
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    • pp.21-38
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    • 2012
  • The proliferation of the Internet and the advent of e-commerce have amplified public concerns about privacy. Accordingly, much research effort has been made on the issue. While existing research on online information privacy has usually focused on the examination of antecedents of personal information disclosure, the literature has not paid attention to the potential changes of the antecedents' effects depending on the user's experience of the service. The current study aims to investigate the moderating role of site usage experience in Internet users' decision on personal information disclosure. Specifically, this study considers two types of antecedents of personal information disclosure on a site - the attributes of personal information requested (sensitivity and relevance of information) and the value of the service provided by the site; and examines how the effects of the antecedents on the disclosure intention are affected by the users'experience of the site. Our analysis of the data gathered through a web-based experiment reveals that site usage experience moderates the relationship between the attributes of personal information and disclosure intention. While usage experience attenuates the negative effect of information sensitivity on disclosure intention, it intensifies the positive impact that relevance of information has on disclosure intention. Based on the analysis results, we provide implications for the mitigation of the Internet users' privacy concerns as well as theoretical implications.

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The Effects of Perceived Stress on Dietary Habits and Oral Health Behaviors in Korean Adolescents (우리나라 청소년의 스트레스 인지수준이 식습관 및 구강건강행태에 미치는 영향)

  • Lee, Min-Young;Choi, Eun-Mi;Chung, Won-Gyun;Son, Jung-Hui;Chang, Sei-Jin
    • Journal of dental hygiene science
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    • v.13 no.4
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    • pp.440-448
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    • 2013
  • The purpose of this study was to analyze the effects of perceived stress on dietary habits and oral health behaviors in Korean adolescents. Data were from the Korea Youth Risk Behavior Web-based Survey (KYRBS) in 2011. A total of 74,186 adolescents were surveyed using the self-administered questionnaire. Logistic regression analyses were performed to elucidate the effects of perceived stress on dietary habits and oral health behaviors. Statistical analyses were conducted, and p<0.05 were considered significant. We found that adolescents with higher stress were more likely to increase the risk of adverse dietary habits (low consumption of fruits, vegetables and milk, high consumption of carbonated soft drinks, fast food and cookie) compared to those with lower stress. Regarding the relationship between perceived stress and oral health behaviors, adolescents with higher stress were less likely to practice oral health behaviors such as brushing teeth after snack consumption and brushing teeth before sleep compared to those with lower stress. This result indicates that adolescents' perceived stress might play a significant role in the negative dietary habits and oral health behavior.

A Study on Cases for Application of Flipped Learning in K-12 Education (초·중등교육에서의 플립러닝 연구사례 분석)

  • Lee, Jeongmin;Park, Hyeon-Kyeong
    • Journal of Digital Convergence
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    • v.14 no.8
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    • pp.19-36
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    • 2016
  • The purpose of this study was to analyze domestic and overseas cases of flipped learning instructional design model and actual classes in K-12 Education, and find out educational implications in order to design effective flipped learning. Papers, 14 articles in domestic and international journals, were collected. As results of the analysis, first, flipped learning instructional model was presented as flipped learning that applied to ADDIE model and 8C model etc. Second, 'Activities before classroom' consisted of watching lecture videos, lecture notes etc. 'Activities during classroom' was checking prior learning in early stage, individual activities and cooperative activities in middle stage, and solving quizzes, reviewing in later stage. After class, students performed tasks and questions&answers. Third, in case of creating lecture video, they used application such as Screencast-o-matic, Explain Everything; In contrast, some cases utilized online web-sites such as YouTube or Phet. Fourth, positive results were shown in learners' academic achievement, motivation and learning attitude etc. This research has a significance in terms of analyzing the flipped learning instructional model and flipped learning activities, and providing the preliminary data to facilitate the design for the effective flipped learning.

Understanding the Performance of Collaborative Filtering Recommendation through Social Network Analysis (소셜네트워크 분석을 통한 협업필터링 추천 성과의 이해)

  • Ahn, Sung-Mahn;Kim, In-Hwan;Choi, Byoung-Gu;Cho, Yoon-Ho;Kim, Eun-Hong;Kim, Myeong-Kyun
    • The Journal of Society for e-Business Studies
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    • v.17 no.2
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    • pp.129-147
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    • 2012
  • Collaborative filtering (CF), one of the most successful recommendation techniques, has been used in a number of different applications such as recommending web pages, movies, music, articles and products. One of the critical issues in CF is why recommendation performances are different depending on application domains. However, prior literatures have focused on only data characteristics to explain the origin of the difference. Scant attentions have been paid to provide systematic explanation on the issue. To fill this research gap, this study attempts to systematically explain why recommendation performances are different using structural indexes of social network. For this purpose, we developed hypotheses regarding the relationships between structural indexes of social network and recommendation performance of collaboration filtering, and empirically tested them. Results of this study showed that density and inconclusiveness positively affected recommendation performance while clustering coefficient negatively affected it. This study can be used as stepping stone for understanding collaborative filtering recommendation performance. Furthermore, it might be helpful for managers to decide whether they adopt recommendation systems.

External validation of IBTR! 2.0 nomogram for prediction of ipsilateral breast tumor recurrence

  • Lee, Byung Min;Chang, Jee Suk;Cho, Young Up;Park, Seho;Park, Hyung Seok;Kim, Jee Ye;Sohn, Joo Hyuk;Kim, Gun Min;Koo, Ja Seung;Keum, Ki Chang;Suh, Chang-Ok;Kim, Yong Bae
    • Radiation Oncology Journal
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    • v.36 no.2
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    • pp.139-146
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    • 2018
  • Purpose: IBTR! 2.0 nomogram is web-based nomogram that predicts ipsilateral breast tumor recurrence (IBTR). We aimed to validate the IBTR! 2.0 using an external data set. Materials and Methods: The cohort consisted of 2,206 patients, who received breast conserving surgery and radiation therapy from 1992 to 2012 at our institution, where wide surgical excision is been routinely performed. Discrimination and calibration were used for assessing model performance. Patients with predicted 10-year IBTR risk based on an IBTR! 2.0 nomogram score of <3%, 3%-5%, 5%-10%, and >10% were assigned to groups 1, 2, 3, and 4, respectively. We also plotted calibration values to observe the actual IBTR rate against the nomogram-derived 10-year IBTR probabilities. Results: The median follow-up period was 73 months (range, 6 to 277 months). The area under the receiver operating characteristic curve was 0.607, showing poor accordance between the estimated and observed recurrence rate. Calibration plot confirmed that the IBTR! 2.0 nomogram predicted the 10-year IBTR risk higher than the observed IBTR rates in all groups. High discrepancies between nomogram IBTR predictions and observed IBTR rates were observed in overall risk groups. Compared with the original development dataset, our patients had fewer high grade tumors, less margin positivity, and less lymphovascular invasion, and more use of modern systemic therapies. Conclusions: IBTR! 2.0 nomogram seems to have the moderate discriminative ability with a tendency to over-estimating risk rate. Continued efforts are needed to ensure external applicability of published nomograms by validating the program using an external patient population.

Trend Analysis of Hazard Substances in/on Agricultural Products Reported by Press (언론에 보도된 농산물 중 유해물질 동향 분석)

  • Lee, Je-Bong;Moon, Byeng-Chul;Jin, Yong-Duk;Kwon, Hye-Young;Im, Geon-Jae;Hong, Moo-Ki;Kang, Kyu-Young
    • The Korean Journal of Pesticide Science
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    • v.15 no.4
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    • pp.434-440
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    • 2011
  • In order to establish the guidance of management and safe use hazard substance, trend analysis of hazard substance in/on agricultural products reported by press for 5 years (2005-2009) was performed. Data for the analysis collected from the articles about hazard substances from web portals, newspapers and so on. The mostly detected harmful factors in/on agricultural products were pesticides residue and heavy metals by the reports by press for last 5 years. The number of detected pesticides was slightly increased from 14 to 34 through the passage of time but the number of cases reported by press was not increased. On the other hand, the number of accidents and reports related to heavy metals were highly increased from 3 to 13 and 42 to 112, respectively. 65 pesticides including chlorpyrifos were detected in domestic agricultural products for the 5 years. Frequently detected pesticides were chlorpyrifos, endosulfan, carbendazim, azoxystrobin, and procymidone. Pesticide residues were repeatedly detected on green vegetables such as a green perilla leaf, a lettuce, a leek, and spinach among crops.

Identifying the Research Fronts in Korean Library and Information Science by Document Co-citation Analysis (문헌동시인용 분석을 통한 한국 문헌정보학의 연구 전선 파악)

  • Lee, Jae Yun
    • Journal of the Korean Society for information Management
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    • v.32 no.4
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    • pp.77-106
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    • 2015
  • By document co-citation analysis with Korean Citation Index (KCI) data, this study accurately identified the research fronts and hot topics in Korean library and information science (LIS) from 2004 to 2013. 159 core papers in LIS domain and their citations are scraped manually from Korean Citation Index web site. In the cluster analysis and network analysis, 159 core papers were grouped into 27 clusters with multiple papers and 8 singlton clusters. Among the 27 clusters which have multple papers, 'LIS education' cluster was the largest with 16 core papers, and 'citation analysis & intellectual structure analysis' cluster had the strongest citation impact according to the ehs-index. Closer observation of the citations to the core papers in each research front showed that 67.5% of the citations were made by LIS research papers and 32.5% of the citations were made by non-LIS research papers. Considering the share of citations and the citation impact growth index, 'local documentation', 'citation analysis & intellectual structure analysis', and 'research trends analysis' were identified as the most emerging research front in Korean library and information science. The analytical methods used in this study have great potential in discovering the characteristics of research fronts in Korean interdisciplinary research domains.

Psychosocial Interventions for Children and Adolescents after a Disaster: A Systematic Literature Review (1991-2015) (재난 후 소아청소년의 정신사회적 개입: 체계적 문헌고찰(1991~2015))

  • Lee, Mi-Sun;Hwang, Jun-Won;Lee, Cheol-Soon;Kim, Ji-Youn;Lee, Ju-Hyun;Kim, Eunji;Chang, Hyoung Yoon;Bae, Seung-Min;Park, Jang-Ho;Bhang, Soo-Young
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.27 no.4
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    • pp.278-305
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    • 2016
  • Objective: The aim of this systematic literature review is to analyze the psychosocial interventions for children and adolescents after disasters. Methods: We conducted a review of the extant research literature from 1991 to 2015 via a comprehensive search of the MEDLINE, EMBASE, Cochrane CENTRAL, PubMed and PsyclNFO databases. The keywords employed in this research included: 'child', 'adolescent', 'youth', 'disaster', 'posttraumatic', 'psychosocial', 'therapy' and 'intervention'. The researchers followed the PRISMA guidelines. A total of 850 articles were screened for their eligibility and fifty-nine were found to meet the study criteria. The final data analysis was performed based on the disaster type, study design, type of intervention, sample size, age, school grade, number of sessions, setting of intervention delivery, providers, approach and parent involvement. Results: Countries worldwide have experienced various kinds of disasters, including earthquakes, hurricanes, vessel accidents, tornados, tsunamis, volcanic eruptions, war, fire, terrorism, and traffic accidents. The types of psychosocial intervention that were conducted after these disasters included: psychological first aid, psychological debriefing, psychoeducation, trauma focused cognitive behavior therapy, eye movement desensitization reprocessing, prolonged exposure therapy, group play therapy and arts therapy, project interventions, school-based interventions and web-based interventions. Conclusion: The findings of the systematic literature review suggest that an appropriate psychosocial intervention could be utilized as evidence-based mental health treatment for children and adolescents after disasters.