• Journal of Pharmaceutical Investigation
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• 제27권1호
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• pp.65-69
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• 1997

To formulate the topical analgesic preparation of a new capsaicin derivative, DA-5018, a skin penetration evaluation system was established and the effect of composition of formulation on skin penetration using this system was evaluated, The effect of massage on hairless mouse skin penetration and inter-day variation of this effect were investigated using test formulations(cream). In massage group, compared with non-massage group, absolute penetration amount of DA-5018 increased and this experimental system was found to be reproducible, The effects of pH of water phase, ratio of oil/water and the concentration of active ingredient in cream on skin penetration were investigated. The permeation of DA-5018 from the cream increased with increasing pH of water phase to 9. But at pH 10, the permeation of DA-5018 decreased, because of the physical instability of the cream. The permeation of DA-5018 from the cream increased with increasing the ratio of oil/water of the cream. The increase of the content of DA-5018 to 0.3% increased the permeation of DA-5018, but at high concentration(1.0%), the permeation of DA5018 decreased, due to the instability of the cream.

• 한국해안해양공학회지
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• 제15권2호
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• pp.71-79
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• 2003

본 논문에서는 염소이온 침투해석에 사용되는 염소이온 확산계수. 염소이온 고정화 관계식, 증발가능 수량에 대한 일반 예측식들을 제시하였다. 이러한 식들을 염소이온 확산 모델링에 대입하여 그 식들의 유효성을 검토하였다. 상대습도와 양생온도의 염소이온 확산에 대한 영향은 주로 확산계수를 변화시켜 고려한다. 상대습도가 증가하면 염소이온 확산깊이는 증가하고 재령이 경과할수록 상대습도가 확산깊이에 미치는 영향은 커진다. 반면에, 양생온도가 증가하면 확산깊이가 조금 증가하지만 재령이 경과할수록 양생온도가 확산깊이에 미치는 영향은 감소한다. 한편, 염소이온의 고정화에 영향을 미치는 시멘트의 $C_3$A양이 증가하면 표면에서는 고정염소이온의 증가로 인해 전체 염소이온량이 증가하지만 깊이가 깊어질수록 확산되는 자유염소이온의 감소로 인해 전체 염소이온량이 감소한다. 물-시멘트비가 감소하면 염소이온의 확산깊이는 급격히 감소하고 염소이온의 확산을 막는 가장 효과적인 방법은 물-시멘트비를 감소시키는 것임을 알 수 있다

• 한국도로학회논문집
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• 제19권2호
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• pp.7-15
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• 2017

PURPOSES : Infiltration of moisture, polluted material, and deicer into concrete, accompanied by freeze and thaw can cause significant deterioration of concrete pavement. In order to protect concrete from deterioration, it is necessary to prevent the infiltration of these concrete external materials. The moisture-repellent agent, which is a surface treatment and maintenance material added to concrete structures to render them water resistant, has advantages such as prevention of water infiltration and security against air permeation. Nano-coat, which is referred to as silicon hydride, is typically used as a moisture-repellent agent. Therefore, in this study, an attempt is made to use penetration-type Nano-coat as an alternative in order to evaluate its applicability through environmental resistance tests. METHODS : This study aimed to evaluate the applicability of penetration-type Nano-coat, which can provide water repellency to concrete, in concrete pavements, through various environmental resistance tests such as freezing and thawing resistance, chloride ion penetration resistance, and surface scaling resistance tests. The applicability of penetration-type Nano-coat was demonstrated based on the specification of KS F 2711, KS F 2456, and ASTM C 672. RESULTS :In the case of penetration-type Nano-coat applied on sound concrete, an increase in concrete durability was demonstrated by the negligible chloride ion penetrability and the absence of scaling, as revealed by visual observation of the surface, after 50 cycles of scaling resistance test. In addition, test result of the application of penetration-type Nano-coat on deteriorated concrete established that concrete surface pretreated by grinding provided improved durability than non-treated concrete. CONCLUSIONS :This study indicates that penetration-type Nano-coat is applicable as an effective alternative, to increase the durability of concrete structures. In addition, it was known that pretreatment of deteriorated concrete surface, such as grinding, is required to improve the long-term performance of concrete pavement.

• 한국콘크리트학회:학술대회논문집
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• 한국콘크리트학회 2006년도 춘계 학술발표회 논문집(II)
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• pp.573-576
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• 2006

The objective of the study is to investigate the depth of penetration of concrete water forced in under pressure. For this purpose, the experiments for the depth of penetration by selecting the factors and levels such as water pressure, pressure time were executed. The flow of water of concrete examined theoretically and experimentally. As a result, It is found that in the case of low water pressure approximately 0.15Mpa or less, the flow is Darcy seepage flow, the same as flow in an ordinary sand stratum, whereas in the case of high water pressure, the flow is diffused seepage flow accompanied by internal deformation of concrete.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2001년도 하계학술대회 논문집 C
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• pp.1789-1791
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• 2001

Recently, Water Blocking Conductor have been used to basic specification at the EHV XLPE Cable, GlobalIy. The area of Middle East have need of severe test condition than existing the Water Penetration Test, specially. In this paper, compare with and investigate the Water Penetration Test's each standard, describes the development Water Blocking Conductor in the high water-pressure for the EDF HN 33-S-51's Water Penetration Test passing.

• Bulletin of the Korean Chemical Society
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• 제35권10호
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• pp.2906-2910
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• 2014

This report introduces Gaussian electrostatic models (GEMs) to account for charge penetration effects in water-water interactions, allowing electrostatic interactions to be accurately described. Three different Gaussian electrostatic models, GEM-3S, GEM-5S, and GEM-6S are designed with s-type Gaussian functions. The coefficients and exponents of the Gaussian functions are optimized using the electrostatic potential (ESP) fitting procedure based on that of the MP2/aug-cc-pVTZ method. The electrostatic energies of ten different water dimers that were calculated with GEM-6S agree well with the results of symmetry-adapted perturbation theory (SAPT), indicating that this designed model can be effectively applied to future water models.

• 한국신재생에너지학회:학술대회논문집
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• 한국신재생에너지학회 2011년도 추계학술대회 초록집
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• pp.81.2-81.2
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• 2011

The gas diffusion layer (GDL) consists of two main parts, the GDL backing layer, called as a substrate and the micro porous layer (MPL) coated on the GDBL. In this process, carbon particles of MPL penetrates to the GDBL consequently forms MPL penetration part. In this study, the micro porous layer (MPL) penetration thickness is determined as a design parameter of the GDL which affect pore size distribution profile through the GDL inducing different mass transfer characteristics. The pore size distribution and water permeability characteristics of the GDL are investigated and the cell performance is evaluated under fully/low humidification conditions. Transient response and voltage instability are also studied. In addition, to determine the effects of MPL penetration on the degradation, the carbon corrosion stress test is conducted. The GDL that have deep MPL penetration thickness shows better performance in high current density region because of enhanced water management, however, loss of penetrated MPL parts is shown after aging and it induces worse water management characteristics.

• 한국농공학회논문집
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• 제54권5호
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• pp.69-77
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• 2012

Relative density, used to express dynamics condition of sand quantitatively, is measured by RI Test, Standard Penetration Test and Cone Penetration Test. Each measurement method has demerits, which is complicated or needs a specific analysis instrument and an analysis of expert. Also the ground is in wet condition commonly because of an unsaturated zone between a saturated zone and a surface, so the behaviour of the ground has different engineering properties unlike the dry ground and it diminishes accuracy of measuring relative density. In this study, the correlation between relative density and penetration of fall cone test in dry condition and wet condition with variation of water content was analyzed and a simple measuring method for relative density was suggested. As a result, there were difference of penetration between dry sands and wet sands, the correlation between relative density and penetration showed linear expression and relative density could be measured by the linear relation.

• Geomechanics and Engineering
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• 제12권5호
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• pp.771-783
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• 2017

Using a transparent fracture replica with aperture size and water-cement ratio (w/c), the factors affecting the penetration behavior of rock grouting were investigated through laboratory experiments. In addition, the waterproof efficiency was estimated by the reduction of water outflow through the fractures after the grout curing process. Penetration behavior shows that grout penetration patterns present similarly radial forms in all experimental cases; however, velocity of grout penetration showed clear differences according to the aperture sizes and water-cement ratio. It can be seen that the waterproof efficiency increased as the aperture size and w/c decreased. During grout injection or curing processes, air bubbles formed and bleeding occurred, both of which affected the waterproof ability of the grouting. These two phenomena can significantly prevent the successful performance of rock grouting in field-scale underground spaces, especially at deep depth conditions. Our research can provide a foundation for improving and optimizing the innovative techniques of rock grouting.

• Geomechanics and Engineering
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• 제24권1호
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• pp.1-14
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• 2021

In this study, a new approach using electrical resistivity measurement was proposed to detect grout penetration and to evaluate the grouting performance for such as waterproof efficiency in single rock fracture. For this purpose, an electrical resistivity monitoring system was designed to collect multi-channel data in real time. This was applied to a system for grout injection/penetration using a transparent fracture replica with various aperture sizes and water-cement mix ratio. The electrical resistivity was measured under various grout penetration conditions in real time, which results were directly compared to the visual observation images of grout penetration/distribution. Moreover, the grouting success status after the curing process was evaluated by measuring the electrical resistivity in relation to changes in frequency in fracture cells where grout injection and penetration were completed. Consequently, it was determined that the electrical resistivity monitoring system could be applied effectively to the detection of successful penetration of grouting into a target area and to actual field evaluation of the grouting performance and long-term stability of underground rock structures.