• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.8
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• pp.2797-2820
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• 2015

In order to accommodate huge number of antennas in a limited antenna size, a large scale antenna array is expected to have a three dimensional (3D) array structure. By using the Active Antenna Systems (AAS), the weights of the antenna elements arranged vertically could be configured adaptively. Then, a degree of freedom (DOF) in the vertical plane is provided for system design. So the three-dimension MIMO (3D MIMO) could be realized to solve the actual implementation problem of the massive MIMO. However, in 3D massive MIMO systems, the pilot contamination problem studied in 2D massive MIMO systems and the inter-cell interference as well as inter-vertical sector interference in 3D MIMO systems with vertical sectorization exist simultaneously, when the number of antenna is not large enough. This paper investigates the interference management towards the above challenges in 3D massive MIMO systems. Here, vertical sectorization based on vertical beamforming is included in the concerned systems. Firstly, a cooperative joint vertical beams adjustment and pilot assignment scheme is developed to improve the channel estimation precision of the uplink with pilots being reused across the vertical sectors. Secondly, a downlink interference coordination scheme by jointly controlling weight vectors and power of vertical beams is proposed, where the estimated channel state information is used in the optimization modelling, and the performance loss induced by pilot contamination could be compensated in some degree. Simulation results show that the proposed joint optimization algorithm with controllable vertical beams' weight vectors outperforms the method combining downtilts adjustment and power allocation.

• Journal of Korean Medical classics
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• v.13 no.1
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• pp.233-252
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• 2000

The contents of Yuk Mee Jee Dae Ron(六微旨大論) are as follows. 1. The Yuk Mee Jee Dae Ron(六微旨大論) is one of the Wun Gi Chil Pean(運氣七篇) which are inserted in So Moon(素問) by Wang Bing(王氷) who compile the So Moon(素問) into 24 volume. Wun Gi Chil Pean(運氣七篇) are Chun Won Ki Dae Ron(天元紀大論), O Woon Heng Dae Ron(五運行大論), Yuk Mee Jee Dae Ron(六微旨大論), Gi kuoo Beun Dae Ron(氣交變大論), O Sang Jeong Dae Ron(五常政大論), Yuk Won Jeong KI Dae Ron(六元正紀大論), Gee Gean Yoo Dae Ron(至眞要大論). 2. It prescribe the Sa Chun(司天) Jae Chun(在泉) Jwa Gan Gi(左間氣) Woo Gan Gi(右間氣). 3. It prescribe the Pheo Gi(標氣) Bon Gi(本氣) Juoog Gi(中氣). 4. It prescribe the Youk BO(六步) and the Sheung Gi(承氣). 5. It prescribe the Hamg Hae Sheung Jae(亢害承制) which is feedback control system between each Yuk Gi(六氣). 6. It prescribe the Sae whae(歲會), the Chun Boo(天符) and the Tae Il Chun Boo(太一天符). 7. It prescribe the active time of Yuk gi(六氣) within a year and Sae gi Whae Dong(歲氣會同). 8. It prescribe the Gi Gieo(氣交) which human beings and all the creation are living on. 9. It prescribe the Bo(步) which are composed of Chun Gi(天氣) and Jee Gi(地氣). 10. It prescribe the Duk(德) Wha(化) Yooung(用) bean(變) which are created by quarrel of Yuk Gi(六氣). 11. It prescribe the outbreak of the Sa Gi(邪氣). 12. It prescribe the Sin Gi(神機) and Gi Rib(氣立). 13. It prescribe all the creations existence are up to the Seoung Gang Chul Ip(升降出入). Like the past, the Yuk Mee Jee Dae Ron(六微旨大論) is include very important concep of the medicine. So the study should be continued with minute attention.

• Structural Engineering and Mechanics
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• v.59 no.2
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• pp.261-275
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• 2016

Effect of silica fume on fresh properties, compressive strength at 28 days and fracture behavior of fly ash concrete composite were studied in this paper. Test results indicated that the fluidity and flowability of fly ash concrete composites decreased and fly ash concrete composite are more cohesive and appear to be sticky with the addition of silica fume. Addition of silica fume was very effective in improving the compressive strength at 28 days of fly ash concrete composite, and the compressive strength of fly ash concrete composite has a trend of increase with the increase of silica fume content. Results also indicated that all the fracture parameters of effective crack length, fracture toughness, fracture energy, the critical crack opening displacement and the maximum crack opening displacement of fly ash concrete composite decreased with the addition of silica fume. When the content of silica fume increased from 3% to 12%, these fracture parameters decreased gradually with the increase of silica fume content. Furthermore, silica fume had great effect on the relational curves of the three-point bending beam specimen. As the silica fume content increased from 3% to 12%, the areas surrounded by the three relational curves and the axes were becoming smaller and smaller, which indicated that the capability of concrete composite containing fly ash to resist crack propagation was becoming weaker and weaker.

• The Korean Journal of Physiology and Pharmacology
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• v.24 no.5
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• pp.403-412
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• 2020

Diabetic nephropathy (DN) is a hyperglycemia-induced progressive development of renal insufficiency. Excessive glucose can increase mitochondrial reactive oxygen species (ROS) and induce cell damage, causing mitochondrial dysfunction. Our previous study indicated that cilostazol (CTZ) can reduce ROS levels and decelerate DN progression in streptozotocin (STZ)-induced type 1 diabetes. This study investigated the potential mechanisms of CTZ in rats with DN and in high glucose-treated mesangial cells. Male Sprague-Dawley rats were fed 5 mg/kg/day of CTZ after developing STZ-induced diabetes mellitus. Electron microscopy revealed that CTZ reduced the thickness of the glomerular basement membrane and improved mitochondrial morphology in mesangial cells of diabetic kidney. CTZ treatment reduced excessive kidney mitochondrial DNA copy numbers induced by hyperglycemia and interacted with the intrinsic pathway for regulating cell apoptosis as an antiapoptotic mechanism. In high-glucose-treated mesangial cells, CTZ reduced ROS production, altered the apoptotic status, and down-regulated transforming growth factor beta (TGF-β) and nuclear factor kappa light chain enhancer of activated B cells (NF-κB). Base on the results of our previous and current studies, CTZ deceleration of hyperglycemia-induced DN is attributable to ROS reduction and thereby maintenance of the mitochondrial function and reduction in TGF-β and NF-κB levels.

• Journal of Electrical Engineering and Technology
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• v.13 no.3
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• pp.1294-1303
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• 2018

This study optimises the no-load voltage waveform of tubular hydro-generators by a simple design scheme. For different centerlines of the pole shoe and damper bar, the optimisation effects on the no-load voltage waveform are investigated in two tubular hydro-generators with different weighted powers (34 MW and 18 MW). The results are compared with those of the traditional stator-slots skewed design. The quality of the no-load voltage waveform was related to the shifting degree, and the different optimisation effects between the integer slot generator (q = 2) and the fractional slot generator (q = 11/2) were analysed. This research can improve the quality of the power output and no-load voltage waveform, and provide an effective reference for improving the industrial design and manufacture level of tubular hydro-generators.

• Structural Engineering and Mechanics
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• v.55 no.6
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• pp.1261-1278
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• 2015

Due to their low intrinsic damping, stay cables in cable-stayed bridges have often exhibited unanticipated and excessive vibrations which result in increasing maintenance frequency and disruption to normal operations of the entire bridges. Mitigation of undesired cable vibration can be achieved by attaching an external damping device near the anchorage. High Damping Rubber (HDR) dampers have many advantages such as compact size, better aesthetics, easy maintenance, temperature stability, and cost benefits; therefore, they have been widely used to increase cable damping. Although a single damper has been shown to reduce cable vibrations, it is not the most effective method due to geometric constraints. This paper proposes the use of two HDR dampers to improve effectiveness and robustness in suppressing cable vibration. Oscillation parameters of the cable-dampers system were investigated in detail by modeling the stay cable as a taut string and each HDR damper as complex-valued impedance and by using an analytical formulation of the complex eigenvalue problem. The problem of two HDR dampers arbitrarily located along a cable is solved and the solution is discussed. Asymptotic formulas to calculate the damping ratios of the cable with two HDR dampers installed near the anchorage(s) are proposed and compared with the exact solutions. Further, a design example is presented in order to justify the methodology. The results of this study show that when the two HDR dampers are installed close to each other on the same end of the cable, some interaction between the dampers leads to reduced damping ratio. When the dampers are on the opposite ends of the cable, they are effective in increasing damping ratio and can provide better vibration reduction to multiple modes.

• Food Science of Animal Resources
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• v.41 no.6
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• pp.936-949
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• 2021

This study discriminated fatty acid profile and flavor characteristics of Beijing You Chicken (BYC) as a precious local breed and Dwarf Beijing You Chicken (DBYC) eggs. Fatty acid profile and flavor characteristics were analyzed to identify differences between BYC and DBYC eggs. Four classification algorithms were used to build classification models. Arachidic acid, oleic acid (OA), eicosatrienoic acid, docosapentaenoic acid (DPA), hexadecenoic acid, monounsaturated fatty acids (MUFA), polyunsaturated fatty acids (PUFA), unsaturated fatty acids (UFA) and 35 volatile compounds had significant differences in fatty acids and volatile compounds by gas chromatography-mass spectrometry (GC-MS) (p<0.05). For fatty acid data, k-nearest neighbor (KNN) and support vector machine (SVM) got 91.7% classification accuracy. SPME-GC-MS data failed in classification models. For electronic nose data, classification accuracy of KNN, linear discriminant analysis (LDA), SVM and decision tree was all 100%. The overall results indicated that BYC and DBYC eggs could be discriminated based on electronic nose with suitable classification algorithms. This research compared the differentiation of the fatty acid profile and volatile compounds of various egg yolks. The results could be applied to evaluate egg nutrition and distinguish avian eggs.

• Current Optics and Photonics
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• v.5 no.2
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• pp.186-190
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• 2021

In this study, a compact, picosecond, mid-infrared 3.8 ㎛ MgO:PPLN optical parametric oscillator (OPO) laser output with high peak power is realized using a master oscillator power amplifier (MOPA) 1 ㎛ solid-state laser seeded by a picosecond fiber laser as the pump source. The pump source was a 50 MHz and 10 ps fiber seed source. After AOM pulse selection and two-stage solid-state amplification, a 1,064 nm laser output with a repetition frequency of 1-2 MHz, pulse width of 9.5 ps, and a maximum average power of 20 W was achieved. Furthermore, a compact short cavity with a unsynchronized pump is adopted through the design of an OPO cavity structure. When the injection pump power was 15 W and the repetition frequency was 1 MHz, the average output power of idler light was 1.19 W, and the corresponding peak power was 119 kW. The optical conversion efficiency was 7.93%. When the repetition frequency was increased to 2 MHz, the average output power of idler light was 1.63 W, the corresponding peak power was 81.5 kW, and the optical conversion efficiency was 10.87%. At the same time, the output wavelength was measured at 3,806 nm, and the beam quality was MX2 = 3.21 and MY2 = 3.34.

• Journal of Ginseng Research
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• v.43 no.3
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• pp.452-459
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• 2019

Background: Ginsenoside compound K(C-K), a major metabolite of ginsenoside, exhibits anticancer activity in various cancer cells and animal models. A cell signaling study has shown that C-K inhibited nuclear factor-kappa B ($NF-{\kappa}B$) pathway in human astroglial cells and liver cancer cells. However, the molecular targets of C-K and the initiating events were not elucidated. Methods: Interaction between C-K and Annexin A2 was determined by molecular docking and thermal shift assay. HepG2 cells were treated with C-K, followed by a luciferase reporter assay for $NF-{\kappa}B$, immunofluorescence imaging for the subcellular localization of Annexin A2 and $NF-{\kappa}B$ p50 subunit, coimmunoprecipitation of Annexin A2 and $NF-{\kappa}B$ p50 subunit, and both cell viability assay and plate clone formation assay to determine the cell viability. Results: Both molecular docking and thermal shift assay positively confirmed the interaction between Annexin A2 and C-K. This interaction prevented the interaction between Annexin A2 and $NF-{\kappa}B$ p50 subunit and their nuclear colocalization, which attenuated the activation of $NF-{\kappa}B$ and the expression of its downstream genes, followed by the activation of caspase 9 and 3. In addition, the overexpression of Annexin A2-K320A, a C-K binding-deficient mutant of Annexin A2, rendered cells to resist C-K treatment, indicating that C-K exerts its cytotoxic activity mainly by targeting Annexin A2. Conclusion: This study for the first time revealed a cellular target of C-K and the molecular mechanism for its anticancer activity.

• Current Optics and Photonics
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• v.3 no.4
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• pp.342-349
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• 2019

We present a theoretical research concerning terahertz (THz) wave generation with $KTiOPO_4$ (KTP) by collinear phase matching (CPM) stimulated polariton scattering (SPS). Both CPM and corresponding nonzero nonlinear coefficients can be simultaneously realized with $s{\rightarrow}f+f$ in yz plane, $s{\rightarrow}f+s$ with ${\theta}$ < ${\Omega}$ in xz plane and $s{\rightarrow}f+f$ with ${\theta}$ < ${\Omega}$ in xz plane. The effective nonlinear coefficients including electronic nonlinearities and ionic nonlinearities are calculated. Based on the parameter values of refractive indices, absorption coefficients and effective nonlinear coefficients, we simulate THz wave intensities generated with CPM SPS by solving coupled wave equations and give the relationship among the maximum THz wave intensity, optimal crystal length and the angle ${\theta}$. The calculation results demonstrate that CPM SPS with KTP can generate THz waves with high intensities and quantum conversion efficiencies.