• Architectural research
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• v.22 no.2
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• pp.41-52
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• 2020

Laboratory buildings with specialized equipment and ventilation systems pose challenges in terms of efficient energy use and initial construction costs. Additionally, lab spaces should have flexible and efficient layouts and provide a comfortable indoor research environment. Therefore, this study aims to identify the correlation between the facade of a building and its interior layout from case studies of energy-efficient research labs and to propose passive energy design strategies for the establishment of an optimal research environment. The case studies in this paper were selected from the American Institute of Architects Committee on the Environment Top Ten Projects and Leadership in Energy and Environmental Design (LEED) certified research lab projects. In this paper, the passive design strategies of space zoning, façade design devices to control heating and cooling loads were analyzed. Additionally, the relationships between these strategies and the interior lab layouts, lab support spaces, offices, and circulation areas were examined. The following four conclusions were drawn from the analysis of various cases: 1) space zoning for grouping areas with similar energy requirements is performed to concentrate similar heating and cooling demands to simplify the HVAC loads. 2) Public areas such as corridor, atrium, or courtyard can serve as buffer zones that employ passive solar design to minimize the mechanical energy load. 3) A balanced window-to-wall ratio (WWR), exterior shading devices, and natural ventilation systems are applied according to the space programming energy requirements to minimize the dependence on mechanical service. 4) Lastly, typical laboratory space zoning categories can be revised, reversed, and even reconfigured to minimize the energy load and adjust to the site context. This study can provide deep insights into various design strategies employed for construction of green laboratories along with intuitive arrangement of various building components such as laboratory spaces, lab support spaces, office spaces, and common public areas. The key findings of this study can contribute towards creating improved designs of laboratory facilities with reduced carbon footprint and greenhouse emissions.

• Journal of the Korean housing association
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• v.25 no.2
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• pp.27-36
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• 2014

The revision of regulations for apartment unit design, which are concerning the area calculating criteria (revised in 1998) and use of balcony (revised in 2005), considerably have increased livable space of apartment unit. This paper aims to verify its effect to apartment unit plan in the aspect of number of rooms and size of each room. For this purpose, 60 and 85 $m^2$ sized apartment unit plans in Seoul Gangnam district have been analysed by construction period, and a conclusion is drawn out as following; (1) The revison of regulations in 1998 and 2005 increased livable space of 60 and 85 $m^2$ sized apartment about 16.4~20.6 $m^2$ area. (2) Bedrooms, living room, dining room and kitchen have no change in size in nominal sense, actually, they increase their size after the fact by converting balcony to livable space. (3) Bathroom, dress room and entrance space have been considerably increased in size, which is possible for available area added in place of wall footprint according to 1998 revision.

• Publications of The Korean Astronomical Society
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• v.13 no.1 s.14
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• pp.149-166
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• 1998

The structure and environments of the molecular clouds near the SNR $HB3(G132.7\pm1.3)$ are studied. The molecular complex which is located at the southern rim of HB3 was proposed by former investigators as the one interacting with HB3. This complex region of $2^{\circ}\times2^{\circ}\;at\;l=133^{\circ}$ has been observed at $^{12}CO,\;^{13}CO,\;J=1-0\;at\;a\;1'$, resolution with the 14-m radio telescope at Taeduk Radio Astronomy Observatory. We have reached to the following four conclusions. The possibility that these molecular complex and HB3 are interacting with each other cannot be supported with any of our data. The morphologies of the two show no similarities. Neither particular features for the interaction are found in the CO lines. The hypothetical 'Molecular wall' which was expected to exist on the northwestern rim of HB3 as a cause for the noncircular morphology of HB3 is turned out to be nonexistent in CO. The molecular complex which resembles a 'bar' at a low resolution is now resolved into a U-shaped shell. It seems that the U-shape is consist of two independent components. No peculiarities, such as unseen masses or bright stars capable of forming HlI regions, are found within the U-shape region. The total mass included in the complex is estimated to be $M_{total}\;=\;2.9\~8.4\times10^5\;M_\bigodot$, which is in good agreement with previous observations within errors. Considering about 12 clumps distinguishable within the complex, the total mass implies that masses of each of clumps are on the order of $10^4\;M_\bigodot$, which makes these good objects for further studies in relation to star-formation. Especially the clumps associated with W3 are worthy for more high resolution observations for better understanding of astrophysical phenomenon ongoing in them.

• Maxillofacial Plastic and Reconstructive Surgery
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• v.34 no.5
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• pp.367-375
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• 2012

Midfacial reconstruction following resection of extensive malignant oral cavity tumors constitutes a challenging problems for reconstructive surgeons. Rectus abdominis muscle free flap (RAMFF) can be considered as the optimal reconstructive option in this case, because this flap has some advantages including consistent deep inferior epigastric artery anatomy, easy to dissect with well defined skin boundaries, acceptable donor site morbidity and the ability to perform simultaneous flap harvest with oral cancer ablation surgery. The rectus abdominis muscle forms an important part of the anterior abdominal wall and flexes the vertebral column, which is a long strap-like muscle divided transversely by three tendinous intersections, fibrous bands which are adherent to the anterior rectus sheath, which is thickly enclosed by the rectus sheath, except for the posterior part below the arcuate line that is usually located midway between the umbilicus and symphysis pubis. Below the arcuate line, this muscle lies in direct contact with the transversalis fascia and parietal peritoneum. For the better understanding of RAMFF as a routine reconstructive procedure in oral and maxillofacial surgery, the constant anatomical findings muse be learned and memorized by the young doctors in the course of the special curriculum periods for the Korean national board of oral and maxillofacial surgery. This review article will discuss the anatomical basis of RAMFF with Korean language.

• KIEAE Journal
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• v.16 no.3
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• pp.113-119
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• 2016

Purpose: In this study, we evaluate the annual energy performance of the detached house which was designed with the aim of zero energy. Method: The experimental house which was constructed in Gonju Chungnam in 2013, is the single family detached house of light weight wood frame with $100m^2$ of heating area. Thermal transmittance of roof (by ISO 10211) and building external walls are designed as $0.10W/m^2K$ and $0.14W/m^2$ respectively and low-e coating vacuum window glazing with PVC frame was installed. Also grid connected PV system and natural-circulation solar water heater was applied and 6kWp capacity of photovoltaic module was installed in pitched roof and $5m^2$ of solar collector in vertical wall facing the south. We analyzed the 2014 annual data of the detached house in which residents were actually living, measured though web-based remote monitoring system. Result: First, as a result, total annual energy consumption and energy production (PV generation and solar hot water) are 7,919kWh and 7,689kWh respectively and the rate of energy independence is 97.1% which is almost close to the zero energy. Second, plug load and hot water of energy consumption by category showed the highest numbers each with 33% and 31%, with following space heating 24%, electric cooker 8%, lighting 3% in order. Hot water supply is relatively higher than space heating because high insulation makes it decreased.

• 유체기계공업학회:학술대회논문집
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• 2006.08a
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• pp.397-400
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• 2006

In this study, we experimentally investigate the possibility of skin-friction drag reduction by series of transverse cavities in a turbulent boundary layer flow. The effects of cavity depth (d), cavity length (l) and cavity spacing (s) on the skin friction drag are examined in the range of $Re_{\theta}\;=\;4030\;{\sim}\;7360$, $d/{\theta}_0\;=\;0.13\;{\sim}1.03$, l/d = 1 ~ 4 and s/d = 5 ~ 20. We perform experiments for twenty different cavity geometries and directly measure total drag force using in-house force measurement system. In most cases, the skin friction drag is increased. At several cases, however, small drag reduction is obtained. The variation of the skin ftiction drag is more sensitive to the cavity length than to the cavity depth or cavity spacing, and drag is reduced at $s/l\;{\geq}\;10$ and $l/{\theta}_0\;{\leq}\;0.26$ irrespective of the cavity depth. At $l/\bar{\theta}_0\;=\;0.13$ and s/l = 10, maximum 2% drag reduction is achieved. When the skin friction drag is reduced, there is little interaction between the flows inside and outside cavity, and the flow changed by the cavity is rapidly recovered at the following crest. A stable vortex is formed inside a cavity in the case of drag reduction. This vortex generates negative skin friction drag at the cavity bottom wall. Although there is form drag due to the cavity itself, total drag is reduced due to the negative skin friction drag.

• Molecules and Cells
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• v.40 no.12
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• pp.935-944
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• 2017

More than 50% of sepsis cases are associated with pneumonia. Sepsis is caused by infiltration of bacteria into the blood via inflammation, which is triggered by the release of cell wall components following lysis. However, the regulatory mechanism of lysis during infection is not well defined. Mice were infected with Streptococcus pneumoniae D39 wild-type (WT) and lipase mutant (${\Delta}lipA$) intranasally (pneumonia model) or intraperitoneally (sepsis model), and survival rate and pneumococcal colonization were determined. LipA and autolysin (LytA) levels were determined by qPCR and western blotting. S. pneumoniae Spd_1447 in the D39 (type 2) strain was identified as a lipase (LipA). In the sepsis model, but not in the pneumonia model, mice infected with the ${\Delta}lipA$ displayed higher mortality rates than did the D39 WT-infected mice. Treatment of pneumococci with serum induced LipA expression at both the mRNA and protein levels. In the presence of serum, the ${\Delta}lipA$ displayed faster lysis rates and higher LytA expression than the WT, both in vitro and in vivo. These results indicate that a pneumococcal lipase (LipA) represses autolysis via inhibition of LytA in a sepsis model.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.21 no.9
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• pp.1115-1125
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• 1997

Experiments have been conducted to obtain local and average heat transfer coefficients associated with impingement of a row of circular, free surface-water jets on a constant heat flux surface. Nozzle arrays are a row of 3 jets (nozzle dia.=4.6 mm) and a row of 5 jets (nozzle dia.=3.6 mm), and the nozzle configuration is Reverse cone type revealed good performance in heat transfer. Nozzle-to-plate spacings ranging from 16 mm to 80 mm were investigated for two jet center to center spacings 25 mm and 37.5 mm in the jet velocity of 3 m/s (R $e_{D}$=27000) to 8 m/s (R $e_{D}$=70000). For a row of 3 jets and a row of 5 jets, the stagnation heat transfer of the central jet is lower than that of adjacent jets. In the wall jet region between jets, for small nozzle-to-plate spacing and large jet velocity, the local maximum in the Nusselt number was observed, however, for small jet velocity or large nozzle-to-plate spacing, the local maximum was not observed. Except for the condition of $V_{O}$=8 m/s and H/D=10, the average Nusselt number reveals the following ranking: a row of 5 jets, a row of 3 jets, single jet. For a row of 3 jet, the maximum average Nusselt number occurs at H/D=8 ~ 10, and for a row of 5 jets, it occurs at H/D=2 ~ 4. Compared with the single jet, enhancement of average heat transfer for a row of 3 jets is approximately 1.52 ~ 2.28 times, and 1.69 ~ 3.75 times for a row of 5 jets.ets.s.

• Archives of Plastic Surgery
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• v.38 no.1
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• pp.85-88
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• 2011

Purpose: Takotsubo cardiomyopathy is a relatively uncommon type of stress-induced cardiomyopathy characterized by transient left ventricular regional wall motion abnormalities. Emotional and physical stresses play a key role in this type of cardiomyopathy in postmenopausal women. The current hypothesis is that the syndrome represents a form of catecholamine surge due to stress or epinephrine-mediated acute myocardial stunning. Methods: A 44-year-old woman had suffered premature ventricular contraction following a cardiogenic shock during a breast augmentation surgery under enflurane anesthesia and tumescent solution infiltration. She was treated with cardiopulmonary resuscitation at a local clinic. Then she was brought to the Emergency Department of the authors' hospital. Results: The woman's echocardiogram showed an ejection fraction of 20~25% with associated basal hyperkinesis and left ventricular apical ballooning. The patient was admitted to the ICU and required inotropic support for two weeks. The patient's condition dramatically improved, and her ejection fraction returned to 70%. Conclusion: It is believed that there were multiple triggering factors of the onset of Takotsubo cardiomyopathy in the woman's social and family history, including infiltration of a large volume of the tumescent solution and VPCs induced by enflurane anesthesia without premedication. The importance of careful history-taking, careful pre-operative consultation on psychological suffering especially for breast surgery, premedication before surgery, patient reassurance, and post-operative psychosocial and emotional assistance was again seen in this case.

• Archives of Plastic Surgery
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• v.41 no.1
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• pp.57-62
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• 2014

Background Achieving symmetry is a key goal in breast reconstruction. Anatomically shaped tabbed expanders are a new tool in the armamentarium of the breast reconstruction surgeon. Suture tabs allow for full control over the expander position and thus inframammary fold position, and, in theory, tabbed expanders mitigate many factors responsible for poor symmetry. The impact of a tabbed expander on breast symmetry, however, has not been formally reported. This study aims to evaluate breast symmetry following expander-implant reconstruction using tabbed and non-tabbed tissue expanders. Methods A chart review was performed of 188 consecutive expander-implant reconstructions that met the inclusion criteria of adequate follow-up data and postoperative photographs. Demographic, oncologic, postoperative complication, and photographic data was obtained for each patient. The photographic data was scored using a 4-point scale assessing breast symmetry by three blinded, independent reviewers. Results Of the 188 patients, 74 underwent reconstruction with tabbed expanders and 114 with non-tabbed expanders. The tabbed cohort had significantly higher symmetry scores than the non-tabbed cohort ($2.82/4{\pm}0.86$ vs. $2.55/4{\pm}0.92$, P=0.034). Conclusions The use of tabbed tissue expanders improves breast symmetry in tissue expander-implant-based breast reconstruction. Fixation of the expander to the chest wall allows for more precise control over its location and counteracts the day-to-day translational forces that may influence the shape and location of the expander pocket, mitigating many factors responsible for breast asymmetry.