• Communications for Statistical Applications and Methods
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• 제17권3호
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• pp.309-318
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• 2010

The construction of asymptotic confidence intervals is considered for the difference of binomial proportions in two doubly sampled data subject to false-positive error. The coverage behaviors of several likelihood based confidence intervals and a Bayesian confidence interval are examined. It is shown that a hierarchical Bayesian approach gives a confidence interval with good frequentist properties. Confidence interval based on the Rao score is also shown to have good performance in terms of coverage probability. However, the Wald confidence interval covers true value less often than nominal level.

• 응용통계연구
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• 제20권2호
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• pp.257-266
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• 2007

모비율에 대한 신뢰구간의 구축에 있어 정규근사에 의한 Wald 신뢰구간이 표준으로 인식되어 왔으나, 최근 여러 학자들에 의해 Wald 신뢰구간은 근사성에서 심각한 문제가 있다는 것이 밝혀지고 있어 Agresti와 Coull(1998)에 의해 제안된 방법이 새로운 표준이 되어 가고 있다. Agresti-Coull 방법은 간편하면서도 근사성 문제를 획기적으로 개선하였으나 모비율에 대한 여러 가지 문제에서 보수적인 신뢰구간을 제시하고 있다. 본 연구에서는 베이지안 접근 방법에 의해 Agresti-Coull 방법의 보수성을 개선한 모비율 선형 함수의 신뢰구간을 제시한다.

• Journal of the Korean Data and Information Science Society
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• 제12권2호
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• pp.71-82
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• 2001

There are several ways to test the equality of two survival distributions under a variety of situations. Tests for equality of two distributions with life-table model for univariate independent response times are reviewed and introduced. It is developed that the methodology to test it for correlated response times where treatments are applied to different independent sets of cohorts. Data, which can be separated into two independent sets, from an angioplasty study where more than one procedure is performed on some patients are used to illustrate this methodology.

• Genomics & Informatics
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• 제18권3호
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• pp.31.1-31.8
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• 2020

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has become a global pandemic. No specific therapeutic agents or vaccines for COVID-19 are available, though several antiviral drugs, are under investigation as treatment agents for COVID-19. The use of convalescent plasma transfusion that contain neutralizing antibodies for COVID-19 has become the major focus. This requires mass screening of populations for these antibodies. While several countries started reporting population based antibody rate, its simple point estimate may be misinterpreted without proper estimation of standard error and confidence intervals. In this paper, we review the importance of antibody studies and present the 95% confidence intervals COVID-19 antibody rate for the Korean population using two recently performed antibody tests in Korea. Due to the sparsity of data, the estimation of confidence interval is a big challenge. Thus, we consider several confidence intervals using Asymptotic, Exact and Bayesian estimation methods. In this article, we found that the Wald method gives the narrowest interval among all Asymptotic methods whereas mid p-value gives the narrowest among all Exact methods and Jeffrey's method gives the narrowest from Bayesian method. The most conservative 95% confidence interval estimation shows that as of 00:00 on September 15, 2020, at least 32,602 people were infected but not confirmed in Korea.

• 응용통계연구
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• 제15권2호
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• pp.355-366
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• 2002

범주형 자료의 구조파악에 주로 이용되는 로짓모형에서 비모수적 방법을 이용한 모수의 신뢰구간추정과 가설검정 등의 통계적 추론에 대하여 살펴보았다. 모수에 대한 통계적 추론에서 정규분포에 근거한 모수적 방법(Wald 방법)보다는 붓스트랩 방법이나 임의순열을 활용한 비모수적 방법이 많이 활용되고 있다. 본 연구에서는 로짓모형의 모수에 대한 비모수적 추론방법으로 붓스트랩(bootstrap)과 임의순열(random permutation)의 두 방법을 고려하고 모의실험을 통하여 가설검정의 검정력과 신뢰구간추정의 포함확률을 비교하였고 사례분석을 다루었다.

• Genomics & Informatics
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• 제18권4호
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• pp.45.1-45.5
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• 2020

With the ongoing rise of coronavirus disease 2019 (COVID-19) pandemic across the globe, interests in COVID-19 antibody testing, also known as a serology test has grown, as a way to measure how far the infection has spread in the population and to identify individuals who may be immune. Recently, many countries reported their population based antibody titer study results. South Korea recently reported their third antibody formation rate, where it divided the study between the general population and the young male youths in their early twenties. As previously stated, these simple point estimates may be misinterpreted without proper estimation of standard error and confidence intervals. In this article, we provide an updated 95% confidence intervals for COVID-19 antibody formation rate for the Korean population using asymptotic, exact and Bayesian statistical estimation methods. As before, we found that the Wald method gives the narrowest interval among all asymptotic methods whereas mid p-value gives the narrowest among all exact methods and Jeffrey's method gives the narrowest from Bayesian method. The most conservative 95% confidence interval estimation shows that as of 00:00 November 23, 2020, at least 69,524 people were infected but not confirmed. It also shows that more positive cases were found among the young male in their twenties (0.22%), three times that of the general public (0.051%). This thereby calls for the quarantine authorities' need to strengthen quarantine managements for the early twenties in order to find the hidden infected people in the population.

• Journal of Korean Dental Science
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• 제2권2호
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• pp.35-41
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• 2009

Objective : This study sought to investigate the clinical survival rate of two implants with different surfaces: resorbable blasting media (RBM)-treated and calcium metaphosphate (CMP)-coated implant. Study design : SSII non-submerged implants (Osstem, Seoul, Korea) were placed in a total of 48 patients with mean age of 38.8. At least 31 patients in the experimental group had a CMP-coated implant, and 1 patient in the control group received a, RBM surface implant. The evaluation period was between April 2006 and December 2007. Radiographs, periotest, clinical periodontal examination, and prosthetic adjustment and occlusion were used. Results : The survival rate of the experimental and control groups after 1 year was 97.2% and 100%, respectively. The Wald confidence interval reported for the experimental group was not inferior to the control group. Conclusion : No significant differences were found between the RBM and CMP groups. The observed data suggest that CMP-coated methods can provide favorable clinical results for the functioning and healing of dental implants.