• Journal of the Korean Society of Food Science and Nutrition
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• v.45 no.6
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• pp.903-910
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• 2016

In this study, the expression level of estrogen receptor in an ovariectomized rat model was effectively enhanced by MS-10, Cirsium japonicum and Thymus vulgaris extract complex, in a reversible manner. MS-10 plays a positive role in enhancing estrogen activity at low concentrations, leading to improved women's health. In order to determine whether or not MS-10 improves menopausal symptoms clinically, a randomized, double-blinded, and placebo-controlled clinical study was carried out on 62 middle-aged women treated with 500 mg of MS-10 or placebo daily for 12 weeks. Clinical menopausal symptoms were evaluated by Kupperman's index (KI) detecting various menopausal symptoms, including hot flushes, parenthesis, insomnia, nervousness, melancholia, dizziness, fatigue, rheumatic pain, palpitations, formication, and headaches. Total KI score decreased significantly by about 18% upon ingestion of MS-10. Colpoxerosis, a main symptom of menopause, was significantly reduced by about 21% upon ingestion of MS-10 in contrast to placebo. In addition, reduction of insulin-like growth factor-1 with age was improved by over 10% upon ingestion of MS-10, whereas there were no significant difference with placebo. No side effects appeared after treatment with MS-10. Thus, MS-10 can be suggested as a plausible natural substance for improving women's health.

• Journal of Bio-Environment Control
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• v.10 no.4
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• pp.232-236
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• 2001

Four air temperature levels of 23, 25, 27 and 29$^{\circ}C$, three humidity levels of 85, 90 and 95% R.H. at photosynthetic photon flux (PPF) of 50 $\mu$mol.m$^{-2}$ .s$^{-1}$ were provided to investigate the effect of vapor pressure deficit on the evapotranspiration rate (EVTR) and graft-taking of watermelon grafted seed-increase. Thus EVTR of grafted seedlings increased with increasing air temperature at high humidity of 95%R.H. At relatively low humidity of 85% R.H., grafted seedlings showed a high EVTR and some wilting of scions was observed at this condition. This result would be ascribed to the low supply of water to vascular bundles according to the insufficient joining of scions and rootstocks. Differences in EVTR between 90% R.H. and 95% R.H. were not observed. Grafted seedlings showed high graft-taking at high relative humidity. Relative humidity had highly influenced to the graft-taking as compared to the air temperature. Graft-taking increased with decreasing vapor pressure deficit. Graft-taking greater than 90% was found at vapor pressure deficit less than 0.4kPa which could be obtained at humidity higher than 90% R.H. Therefore it is required to control the humidity higher than 90% R.H. for suppressing EVTR of grafted seedlings and preventing some wilting of scoins and thus enhancing the graft-taking of grafted seedlings.

• Journal of the Korean Applied Science and Technology
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• v.31 no.4
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• pp.703-710
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• 2014

The following is the study result of herbal tea roasted at different temperatures between $80{\sim}140^{\circ}C$. Depending on treatment temperature the water content decreased, some carbonization occurred and crude ash content relatively increased. Also crude protein and crude fat decreased little. Solid elution rate of herbal tea showed 0.15~0.32%(w/w) and the rate of solid elution decreased with higher roasting temperature. There was no big change in $80{\sim}110^{\circ}C$ treatment section but the solid elution decreased rapidly in $110{\sim}140^{\circ}C$ section. The reason for decreasing solid elution rate at higher treatment temperature is because the compact inner tissue makes elution difficult. Benzopyrene content (0.29~0.51ppb) showed a tendency to increase with higher treating temperature. From this result, the $B({\alpha})P$ content differed depending on the treatment temperature and raw materials. In case of roasting, the actual inside temperature is around $200^{\circ}C$ but since the surface temperature of the roaster reaches around $2000^{\circ}C$ some portion of $B({\alpha})P$ content was presumed to be produced from the area that came in contact with this surface. When the processing which is a main component of food carbohydrate, protein, fat reason despite serve heat treatment as a whole is to be detected even though the $B({\alpha})P$ in this way is considered to be.

• Environmental Analysis Health and Toxicology
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• v.19 no.1
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• pp.33-40
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• 2004

Benzoyl peroxide is a High Production Volume Chemical, which is produced about 1,371 tons/year in Korea as of 2001 survey. The substance is mainly used as initiators in polymerization, catalysts in the plastics industry, bleaching agents for flour and medication for acne vulgaris. In this study, Quantitative Structure-Activity Relationships (QSAR) are used for getting adequate information on the physical -chemical properties of this chemical. And hydrolysis in water, acute toxicity to aquatic and terrestrial organisms for benzoyl peroxide were studied. The physical -chemical properties of benzoyl peroxide were estimated as followed; vapor pressure=0.00929 Pa, Log $K_{ow}$ = 3.43, Henry's Law constant=3.54${\times}$10$^{-6}$ atm-㎥/mole at $25^{\circ}C$, the half-life of photodegradation=3 days and bioconcentration factor (BCF)=92. Hydrolysis half-life of benzoyl peroxide in water was 5.2 hr at pH 7 at $25^{\circ}C$ and according to the structure of this substance hydrolysis product was expected to benzoic acid. Benzoyl peroxide has toxic effects on the aquatic organisms. 72 hr-Er $C_{50}$ (growth rate) for algae was 0.44 mg/1.,48 hr-E $C_{50}$ for daphnia was 0.07mg/L and the 96hr-L $C_{50}$ of acute toxicity to fish was 0.24mg/L. Acute toxicity to terrestrial organisms (earth worm) of benzoyl peroxide was low (14 day-L $C_{50}$ = > 1,000 mg/kg). Although benzoyl peroxide is high toxic to aquatic organisms, the substance if not bioaccumulated because of the rapid removal by hydrolysis (half-life=5.2 hr at pH 7 at $25^{\circ}C$) and biodegradation (83% by BOD after 21 days). The toxicity observed is assumed to be due to benzoyl peroxide rather than benzoic acid, which shows much lower toxicity to aquatic organisms. One can assume that effects occur before hydrolysis takes place. From the acute toxicity value of algae, daphnia and fish, an assessment factor of 100 was used to determine the predicted no effect concentration (PNEC). The PNEC was calculated to be 0.7$\mu\textrm{g}$/L based on the 48 hr-E $C_{50}$ daphnia (0.07 mg/L). The substance shows high acute toxicity to aquatic organisms and some information indicates wide-dispersive ore of this substance. So this substance is, a candidate for further work, even if it hydrolysis rapidly and has a low bioaccumulation potential. This could lead to local concern for the aquatic environment and therefore environmental exposure assessment is recommended.

• Journal of Korean Foot and Ankle Society
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• v.7 no.1
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• pp.83-87
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• 2003

Purpose: To evaluate the factors which affect the level of the amputation for treatment of DM foot excluding arterial occlusion. Materials and Methods: We selected 30 patients (10 of major amputations, 20 of minor amputations) who were amputated from May, 1999 to April, 2001 because of DM foot. Major amputation is BK amputation, and minor amputation is amputation below ankle joint. Gender, age, size of the wound, extent of the necrosis, infectious organism, medical com orbidity, duration of DM and blood glucose level, duration of DM foot and treatment history were investigated. Results: In major amputations, male to female ratio was 9:1, average of the age was 63.8, the average of sizes of the wound was 16cm2, duration of DM was 15.0 years, duration of DM foot was 10.6 weeks, and 80% of patients had necrosis and the organisms were S. aureus, E. faecium, Streptococcus, P. vulgaris, average of the blood glucose levels was 301 and 40% of them had been treated for DM foot. In minor amputations, male to female ration was 9:1, average of the age was 56.6, the average of sizes of the wound was 4.8cm2, duration of DM was 11.2 years, duration of DM foot was 5.7 weeks, and 40% of patients had necrosis and the organisms were S. aureus, Streptococcus, M. morganini, E. faecium, average of the blood glucose levels was 257 and 20% of them had been treated for DM foot. Conclusion: In DM foot patients, extents of the necrosis, duration of DM, duration of DM foot, the infectious organism were significant factors to decide extent of the amputation level.

• Korean Journal of Weed Science
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• v.4 no.2
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• pp.211-218
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• 1984

In order to establish the chemical weed control systems in orchard, field experiments were conducted to evaluate the effects of spray methods and mixing of herbicides. The mixtured dosage of glyphosate 100cc/10a and 2,4-D 75㏄/10a showed higher control effects than mono-treatment of glyphosate and paraquat on Artemisia vulgaris var. indica and Polygonum hydropiper L. And oxyfluorfen was more effective in reducing the cover rate and dry weight of weeds than simazine and alachlor on 75th day after treatment. In the mixing experiment of land and foliar appling herbicides. The effect of glyphosate on May 17 followed by oxyfluorfen on June 12 showed the best control effect.

• Korean Journal of Organic Agriculture
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• v.13 no.4
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• pp.413-422
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• 2005

This study was carried out to investigate the effect of different mixture ratios of vermicasts on the growth of leaf beet(Beta vulgaris var. cicla), young radish (Raphanus sativus L), spinach(Spinacia oleracea) and lettuce(Lactuca sativa) The mixture of ratios of vermicast(fermented pig manure with sawdust) and peatmoss were 100%+0%, 60%+40%, 40%+60% and 0%+100%(control), respectively. The bulk density, particle density, pH, electrolytic conductivity, ash, total nitrogen, cation exchange capacity, available phosphorous and exchangeable cations increased significantly compared to those grown in the 100% of peatmoss(control). The significantly higher values of plant length, leaf area, shoot dry weight, root weight, root length and biological yield obtained were $40{\sim}100%$ and 40% of vermicast in leaf beet and lettuce, respectively. The young radish and spinach showed that significantly differences of shoot dry weight, root weight and biological yield in the mixture ratios of vermicast were $40{\sim}60%$ and 40% in young radish and spinach, respectively.

• Korean Journal of Ecology and Environment
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• v.51 no.1
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• pp.29-39
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• 2018

Long-term variation of zooplankton community and species composition was studied from 2003 to 2014 in a deep reservoir, Lake Soyang, in monsoon climate region, Korea. In addition, we examined the correlation with environmental factors. Annual precipitation of watershed showed a large variation in the $705{\sim}1,779mm\;yr^{-1}$ and more than 70% of it was being concentrated from June to September. The water quality of Lake Soyang was shown a clearly seasonal variations and particularly turbid water flowing into the lake during rainy season was the most important environmental factors. Zooplankton community in Lake Soyang showed a significant difference before and after 2006. Zooplankton biomass has shown a large increase and also showed a change in the zooplankton community structure since 2006. The of zooplankton showed positive correlation with temperature and BOD, Chl. a, TP concentration. These results are considered that nutrient and organic matter contained in the turbid water influences the increase in zooplankton biomass and species composition. However, water quality was limited to account for the increase in biomass of zooplankton. For example, increase of small zooplankton density (rotifer; Keratella cochlearis, Polyarthra vulgaris) in spring which is dominated by diatoms (large size; Melosira, Synedra etc.) is considered as a bottom-up effect by the microbial loop. And increased density of crustaceans in autumn was considered a top-down effects by the relationship between predator and prey of microzooplankton and mesozooplankton. In other words the inflow of allochthonous organic matter during rainy season also affected to zooplankton food web in Lake Soyang. In conclusion, biomass, diversity and long-term variations of zooplankton in Lake Soyang were determined by physico-chemical factors but also it is considered that biological interactions is important.

• Journal of Life Science
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• v.15 no.2 s.69
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• pp.211-214
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• 2005

The studies were conducted to obtain basic informations on inheritance of some quantitative characters in kidney bean (Phaseolus vulgaris L.). Seven parents (Felibon, Renka, Processor, Kaboom, $BO_{22}$, Local variety $\#1$ and Local variety $\#2)$ and $F_1$ hybrids of 21 crosses from a set of diallel cross among varieties were used to estimate combining ability for eight agronomic characters such as days to flowering, days to maturity, stem length, pod numbers per plant, pod length, grain numbers per plant, 100-grain weight and grain weight per plant. General combining ability (GCA) and specific combining ability (SCA) were significantly different among all characters, and values of GCA were greater than those of SCA in all characters except number of grains per plant. In effect of GCA, Felibon expressed high GCA effect for days to flowering and number of grains per plant. Local variety $\#1$ showed high GCA effect for 100-grain weight and stem length. Local variety $\#2$appeared to high GCA effect for 100-grain weight and grain weight per plant. Processor expressed high GCA effect for days to maturity and grain weight per plant. Kaboom showed high GCA effect days to flowering and days to maturity. $BO_{22}$ appeared high GCA effect for all characters except for days to flowering, days to maturity and stem length. In the SCA effect, crosses of Felibonx Renka and Local variety $\#2{\times}Processor$ exhibited in high negative effect for days to flowering. Thus, these crosses were evaluated to useful for breeding early maturing variety. Crosses of breeding high yield variety were considered of $Felibon{\times}Local$ variety $\#1$, $Felibon{\times}Renka$ and Local variety $\#2{\times}BO_{22}$.

• The Korean Journal of Mycology
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• v.40 no.1
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• pp.65-68
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• 2012

In July and August 2011, a disease suspected to be Rhizopus soft rot was observed on peach (Prunus persica var. vulgaris) at the Wholesale Market for Agricultural Products, Jinju, Korea. The first symptom of soft rot on peach is a water-soaked appearance of the affected tissue. The infected parts later disintegrated into a mushy mass of disorganized cells followed by rapid softening of the diseased tissue. The lesion on peach was rapidly softened and rotted, then became brown or dark brown. Optimum temperature for mycelial growth of the causal fungus on PDA was $30^{\circ}C$and growth was still apparent at $37^{\circ}C$Sporangiophores were 6~20 ${\mu}m$ in diameter. Sporangia were globose and 35~200 ${\mu}m$ in size. The color of sporangia was brownish-grey to blackish-grey at maturity. Sporangiospores were sub-globose, brownish- black streaked and 5~10 ${\mu}m$ in size. Columella were globose to sub-globose and 85~120 ${\mu}m$ in size. On the basis of mycological characteristics, pathogenicity test, and molecular identification, the causal fungus was identified as Rhizopus oryzae Went & Prinsen Geerligs. To our knowledge, this is the first report of soft rot caused by R. oryzae on peach in Korea.